LOCUS HUMAPE6ONC 2625 bp mRNA linear HUM 27-APR-1993
DEFINITION Homo sapiens papillomavirus E6 oncogenic protein-associated protein
(E6-AP) mRNA, 3' end.
ACCESSION L07557
VERSION L07557.1
KEYWORDS oncogenic protein-associated protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2625)
AUTHORS Huibregtse,J.M., Scheffner,M. and Howley,P.M.
TITLE Cloning and expression of the cDNA for E6-AP, a protein that
mediates the interaction of the human papillomavirus E6 oncoprotein
with p53
JOURNAL Mol. Cell. Biol. 13 (2), 775-784 (1993)
PUBMED 8380895
COMMENT Original source text: Homo sapiens foreskin cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2625
/db_xref="H-InvDB:HIT000191841"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="keratinocyte"
/tissue_type="foreskin"
CDS <1..2625
/codon_start=1
/product="oncogenic protein-associated protein"
/protein_id="AAA35542.1"
/translation="SGEPQSDDIEASRMKRAAAKHLIERYYHQLTEGCGNEACTNEFC
ASCPTFLRMDNNAAAIKALELYKINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIK
MNKKGARIDFKDVTYLTEEKVYEILELCREREDYSPLIRVIGRVFSSAEALVQSFRKV
KQHTKEELKSLQAKDEDKDEDEKEKAACSAAAMEEDSEASSSRIGDSSQGDNNLQKLG
PDDVSVDIDAIRRVYTRLLSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNL
FIIGMENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQ
QLITYKVISNEFNSRNLVNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHN
EEDDEEPIPESSELTLQELLGEERRNKKGLRVDPLETELGVKTLDCRKPLIPFEEFIN
EPLNEVLEMDKDYTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITV
LYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDE
GGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYN
NCILDVHFPMVVYRKLMGKKGLFVDLGDSHPVLYQSLKDLLEYVGNVEDDMMITFQIS
QTNLFGNPMMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVT
NESPLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTD
EQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEK
LKERLLKAITYAKGFGML"
BASE COUNT 875 a 457 c 569 g 724 t
ORIGIN
1 tcaggagaac ctcagtctga cgacattgaa gctagccgaa tgaagcgagc agctgcaaag
61 catctaatag aacgctacta ccaccagtta actgagggct gtggaaatga agcctgcacg
121 aatgagtttt gtgcttcctg tccaactttt cttcgtatgg ataataatgc agcagctatt
181 aaagccctcg agctttataa gattaatgca aaactctgtg atcctcatcc ctccaagaaa
241 ggagcaagct cagcttacct tgagaactcg aaaggtgccc ccaacaactc ctgctctgag
301 ataaaaatga acaagaaagg cgctagaatt gattttaaag atgtgactta cttaacagaa
361 gagaaggtat atgaaattct tgaattatgt agagaaagag aggattattc ccctttaatc
421 cgtgttattg gaagagtttt ttctagtgct gaggcattgg tacagagctt ccggaaagtt
481 aaacaacaca ccaaggaaga actgaaatct cttcaagcaa aagatgaaga caaagatgaa
541 gatgaaaagg aaaaagctgc atgttctgct gctgctatgg aagaagactc agaagcatct
601 tcctcaagga taggtgatag ctcacaggga gacaacaatt tgcaaaaatt aggccctgat
661 gatgtgtctg tggatattga tgccattaga agggtctaca ccagattgct ctctaatgaa
721 aaaattgaaa ctgcctttct caatgcactt gtatatttgt cacctaacgt ggaatgtgac
781 ttgacgtatc acaatgtata ctctcgagat cctaattatc tgaatttgtt cattatcgga
841 atggagaata gaaatctcca cagtcctgaa tatctggaaa tggctttgcc attattttgc
901 aaagcgatga gcaagctacc ccttgcagcc caaggaaaac tgatcagact gtggtctaaa
961 tacaatgcag accagattcg gagaatgatg gagacatttc agcaacttat tacttataaa
1021 gtcataagca atgaatttaa cagtcgaaat ctagtgaatg aatttaacag tcgaaatcta
1081 gtgaatgatg atgatgccat tgttgctgct tcgaagtgct tgaaaatggt ttactatgca
1141 aatgtagtgg gaggggaagt ggacacaaat cacaatgaag aagatgatga agagcccatc
1201 cctgagtcca gcgagctgac acttcaggaa cttttgggag aagaaagaag aaacaagaaa
1261 ggtcttcgag tggaccccct ggaaactgaa cttggtgtta aaaccctgga ttgtcgaaaa
1321 ccacttatcc cttttgaaga gtttattaat gaaccactga atgaggttct agaaatggat
1381 aaagattata cttttttcaa agtagaaaca gagaacaaat tctcttttat gacatgtccc
1441 tttatattga atgctgtcac aaagaatttg ggattatatt atgacaatag aattcgcatg
1501 tacagtgaac gaagaatcac tgttctctac agcttagttc aaggacagca gttgaatcca
1561 tatttgagac tcaaagttag acgtgaccat atcatagatg atgcacttgt ccggctagag
1621 atgatcgcta tggaaaatcc tgcagacttg aagaagcagt tgtatgtgga atttgaagga
1681 gaacaaggag ttgatgaggg aggtgtttcc aaagaatttt ttcagctggt tgtggaggaa
1741 atcttcaatc cagatattgg tatgttcaca tacgatgaat ctacaaaatt gttttggttt
1801 aatccatctt cttttgaaac agagggtcag tttactctga ttggcatagt actgggtctg
1861 gctatttaca ataactgtat actggatgta cattttccca tggttgtcta caggaagcta
1921 atggggaaaa aaggactttt cgtcgacttg ggagactctc acccagttct atatcagagt
1981 ttaaaagatt tattggagta tgttgggaat gtggaagatg acatgatgat cactttccag
2041 atatcacaga caaatctttt tggtaaccca atgatgtatg atctaaagga aaatggtgat
2101 aaaattccaa ttacaaatga aaacaggaag gaatttgtca atctttattc tgactacatt
2161 ctcaataaat cagtagaaaa acagttcaag gcttttcgga gaggttttca tatggtgacc
2221 aatgaatctc ccttaaagta cttattcaga ccagaagaaa ttgaattgct tatatgtgga
2281 agccgcaatc tagatttcca agcactagaa gaaactacag aatatgacgg tggctatacc
2341 agggactctg ttctgattag ggagttctgg gaaatcgttc attcatttac agatgaacag
2401 aaaagactct tcttgcagtt tacaacgggc acagacagag cacctgtggg aggactagga
2461 aaattaaaga tgattatagc caaaaatggc ccagacacag aaaggttacc tacatctcat
2521 acttgcttta atgtgctttt acttccggaa tactcaagca aagaaaaact taaagagaga
2581 ttgttgaagg ccatcacgta tgccaaagga tttggcatgc tgtaa
//