LOCUS HUMPKCTH 2705 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human protein kinase C theta (PKC) mRNA, complete cds.
ACCESSION L07032
VERSION L07032.1
KEYWORDS protein kinase C theta.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2705)
AUTHORS Baier,G., Telford,D., Giampa,L., Coggeshall,K.M.,
Baier-Bitterlich,G., Isakov,N. and Altman,A.
TITLE Molecular cloning and characterization of PKC theta, a novel member
of the protein kinase C (PKC) gene family expressed predominantly
in hematopoietic cells
JOURNAL J. Biol. Chem. 268 (7), 4997-5004 (1993)
PUBMED 8444877
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2705
/db_xref="H-InvDB:HIT000191806"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkat"
/cell_type="hematopoietic"
gene 1..2705
/gene="PKC"
CDS 22..2142
/gene="PKC"
/codon_start=1
/product="protein kinase C-theta"
/protein_id="AAA60101.1"
/translation="MSPFLRIGLSNFDCGSCQSCQGEAVNPYCAVLVKEYVESENGQM
YIQKKPTMYPPWDSTFDAHINKGRVMQIIVKGKNVDLISETTVELYSLAERCRKNNGK
TEIWLELKPQGRMLMNARYFLEMSDTKDMNEFETEGFFALHQRRGAIKQAKVHHVKCH
EFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAINSRE
TMFHKERFKIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTK
VANLCGINQKLMAEALAMIESTQQARCLRDTEQIFREGPVEIGLPCSIKNEARPPCLP
TPGKREPQGISWESPLDEVDKMCHLPEPELNKERPSLQIKLKIEDFILHKMLGKGSFG
KVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKRVLSLAWEHPFLTHMFCTFQT
KENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEIILGLQFLHSKGIVYRDLKLD
NILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAPEILLGQKYNHSVDWWSFG
VLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWLEKEAKDLLVKLFVREPEKRLGV
RGDIRQHPLFREINWEELERKEIDPPFRPKVKSPFDCSNFDKEFLNEKPRLSFADRAL
INSMDQNMFRNFSFMNPGMERLIS"
BASE COUNT 764 a 627 c 665 g 649 t
ORIGIN
1 tgctcgctcc agggcgcaac catgtcgcca tttcttcgga ttggcttgtc caactttgac
61 tgcgggtcct gccagtcttg tcagggcgag gctgttaacc cttactgtgc tgtgctcgtc
121 aaagagtatg tcgaatcaga gaacgggcag atgtatatcc agaaaaagcc taccatgtac
181 ccaccctggg acagcacttt tgatgcccat atcaacaagg gaagagtcat gcagatcatt
241 gtgaaaggca aaaacgtgga cctcatctct gaaaccaccg tggagctcta ctcgctggct
301 gagaggtgca ggaagaacaa cgggaagaca gaaatatggt tagagctgaa acctcaaggc
361 cgaatgctaa tgaatgcaag atactttctg gaaatgagtg acacaaagga catgaatgaa
421 tttgagacgg aaggcttctt tgctttgcat cagcgccggg gtgccatcaa gcaggcaaag
481 gtccaccacg tcaagtgcca cgagttcact gccaccttct tcccacagcc cacattttgc
541 tctgtctgcc acgagtttgt ctggggcctg aacaaacagg gctaccagtg ccgacaatgc
601 aatgcagcaa ttcacaagaa gtgtattgat aaagttatag caaagtgcac aggatcagct
661 atcaatagcc gagaaaccat gttccacaag gagagattca aaattgacat gccacacaga
721 tttaaagtct acaattacaa gagcccgacc ttctgtgaac actgtgggac cctgctgtgg
781 ggactggcac ggcaaggact caagtgtgat gcatgtggca tgaatgtgca tcatagatgc
841 cagacaaagg tggccaacct ttgtggcata aaccagaagc taatggctga agcgctggcc
901 atgattgaga gcactcaaca ggctcgctgc ttaagagata ctgaacagat cttcagagaa
961 ggtccggttg aaattggtct cccatgctcc atcaaaaatg aagcaaggcc gccatgttta
1021 ccgacaccgg gaaaaagaga gcctcagggc atttcctggg agtctccgtt ggatgaggtg
1081 gataaaatgt gccatcttcc agaacctgaa ctgaacaaag aaagaccatc tctgcagatt
1141 aaactaaaaa ttgaggattt tatcttgcac aaaatgttgg ggaaaggaag ttttggcaag
1201 gtcttcctgg cagaattcaa gaaaaccaat caatttttcg caataaaggc cttaaagaaa
1261 gatgtggtct tgatggacga tgatgttgag tgcacgatgg tagagaagag agttctttcc
1321 ttggcctggg agcatccgtt tctgacgcac atgttttgta cattccagac caaggaaaac
1381 ctcttttttg tgatggagta cctcaacgga ggggacttaa tgtaccacat ccaaagctgc
1441 cacaagttcg acctttccag agcgacgttt tatgctgctg aaatcattct tggtctgcag
1501 ttccttcatt ccaaaggaat agtctacagg gacctgaagc tagataacat cctgttagac
1561 aaagatggac atatcaagat cgcggatttt ggaatgtgca aggagaacat gttaggagat
1621 gccaagacga ataccttctg tgggacacct gactacatcg ccccagagat cttgctgggt
1681 cagaaataca accactctgt ggactggtgg tccttcgggg ttctccttta tgaaatgctg
1741 attggtcagt cgcctttcca cgggcaggat gaggaggagc tcttccactc catccgcatg
1801 gacaatccct tttacccacg gtggctggag aaggaagcaa aggaccttct ggtgaagctc
1861 ttcgtgcgag aacctgagaa gaggctgggc gtgaggggag acatccgcca gcaccctttg
1921 tttcgggaga tcaactggga ggaacttgaa cggaaggaga ttgacccacc gttccggccg
1981 aaagtgaaat caccatttga ctgcagcaat ttcgacaaag aattcttaaa cgagaagccc
2041 cggctgtcat ttgccgacag agcactgatc aacagcatgg accagaatat gttcaggaac
2101 ttttccttca tgaaccccgg gatggagcgg ctgatatcct gaatcttgcc cctccagaga
2161 caggaaagaa tttgccttct ccctgggaac tggttcaaga gacactgctt gggttccttt
2221 ttcaacttgg aaaaagaaag aaacactcaa caataaagac tgagacccgt tcgcccccat
2281 gtgactttat ctgtagcaga aaccaagtct acttcactaa tgacgatgcc gtgtgtctcg
2341 tctcctgaca tgtctcacag acgctcctga agttaggtca ttactaacca tagttattta
2401 cttgaaagat gggtctccgc acttggaaag gtttcaagac ttgatactgc aataaattat
2461 ggctcttcac ctgggcgcca actgctgatc aacgaaatgc ttgttgaatc aggggcaaac
2521 ggagtacaga cgtctcaaga ctgaaacggc cccattgcct ggtctagtag cggatctcac
2581 tcagccgcag acaagtaatc actaacccgt tttattctat cctatctgtg gatgtataaa
2641 tgctgggggc cagccctgga taggttttta tgggaattct ttacaataaa catagcttgt
2701 acttg
//