LOCUS HUMMKK 1455 bp mRNA linear HUM 27-APR-1993
DEFINITION Homo sapiens MAP kinase kinase mRNA, complete cds.
ACCESSION L05624
VERSION L05624.1
KEYWORDS MAP kinase kinase; kinase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1455)
AUTHORS Seger,R., Seger,D., Lozeman,F.J., Ahn,N.G., Graves,L.M.,
Campbell,J.S., Ericsson,L., Harrylock,M., Jensen,A.M. and
Krebs,E.G.
TITLE Human T-cell mitogen-activated protein kinase kinases are related
to yeast signal transduction kinases
JOURNAL J. Biol. Chem. 267 (36), 25628-25631 (1992)
PUBMED 1281467
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1455
/db_xref="H-InvDB:HIT000191683"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="T-cell"
CDS 34..1215
/codon_start=1
/product="MAP kinase kinase"
/protein_id="AAA36318.1"
/translation="MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDE
QQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLE
IKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGR
IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDS
MANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFG
CQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEF
QDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAG
V"
BASE COUNT 358 a 354 c 398 g 345 t
ORIGIN
1 ggcggagttg gaagcgcgtt acccgggtcc aaaatgccca agaagaagcc gacgcccatc
61 cagctgaacc cggcccccga cggctctgca gttaacggga ccagctctgc ggagaccaac
121 ttggaggcct tgcagaagaa gctggaggag ctagagcttg atgagcagca gcgaaagcgc
181 cttgaggcct ttcttaccca gaagcagaag gtgggagaac tgaaggatga cgactttgag
241 aagatcagtg agctgggggc tggcaatggc ggtgtggtgt tcaaggtctc ccacaagcct
301 tctggcctgg tcatggccag aaagctaatt catctggaga tcaaacccgc aatccggaac
361 cagatcataa gggagctgca ggttctgcat gagtgcaact ctccgtacat cgtgggcttc
421 tatggtgcgt tctacagcga tggcgagatc agtatctgca tggagcacat ggatggaggt
481 tctctggatc aagtcctgaa gaaagctgga agaattcctg aacaaatttt aggaaaagtt
541 agcattgctg taataaaagg cctgacatat ctgagggaga agcacaagat catgcacaga
601 gatgtcaagc cctccaacat cctagtcaac tcccgtgggg agatcaagct ctgtgacttt
661 ggggtcagcg ggcagctcat cgactccatg gccaactcct tcgtgggcac aaggtcctac
721 atgtcgccag aaagactcca ggggactcat tactctgtgc agtcagacat ctggagcatg
781 ggactgtctc tggtagagat ggcggttggg aggtatccca tccctcctcc agatgccaag
841 gagctggagc tgatgtttgg gtgccaggtg gaaggagatg cggctgagac cccacccagg
901 ccaaggaccc ccgggaggcc ccttagctca tacggaatgg acagccgacc tcccatggca
961 atttttgagt tgttggatta catagtcaac gagcctcctc caaaactgcc cagtggagtg
1021 ttcagtctgg aatttcaaga ttttgtgaat aaatgcttaa taaaaaaccc cgcagagaga
1081 gcagatttga agcaactcat ggttcatgct tttatcaaga gatctgatgc tgaggaagtg
1141 gattttgcag gttggctctg ctccaccatc ggccttaacc agcccagcac accaacccat
1201 gctgctggcg tctaagtgtt tgggaagcaa caaagagcga gtcccctgcc cggtggtttg
1261 ccatgtcgct tttgggcctc cttcccatgc ctgtctctgt tcagatgtgc atttcacctg
1321 tgacaaagga tgaagaacac agcatgtgcc aagattctac tcttgtcatt tttaatatta
1381 ctgtctttat tcttattact attattgttc ccctaagtgg attggctttg tgcttggggc
1441 tatttgtgtg tatcc
//