LOCUS HUMSEROTON 1554 bp DNA linear HUM 26-JUL-1993
DEFINITION Human serotonin receptor gene, complete cds.
ACCESSION L05597
VERSION L05597.1
KEYWORDS 5-hydroxytryptamine receptor; serotonin receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1554)
AUTHORS Lovenberg,T.W., Erlander,M.G., Baron,B.M., Racke,M., Slone,A.L.,
Siegel,B.W., Craft,C.M., Burns,J.E., Danielson,P.E. and
Sutcliffe,J.G.
TITLE Molecular cloning and functional expression of 5-HT1E-like rat and
human 5-hydroxytryptamine receptor genes
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 90 (6), 2184-2188 (1993)
PUBMED 8384716
COMMENT Original source text: Homo sapiens male DNA.
FEATURES Location/Qualifiers
source 1..1554
/db_xref="H-InvDB:HIT000397384"
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
/sex="male"
CDS 225..1325
/function="inhibits adenylate cyclase"
/standard_name="5-HT1E receptor"
/note="putative"
/codon_start=1
/product="serotonin receptor"
/protein_id="AAA36605.1"
/translation="MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLV
IAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSV
DITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLF
WRHQGTSRDDECIIKHDHIVSTIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQAS
RIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEK
SWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVNVCDKCKISEEMSNFLAW
LGYLNSLINPLIYTIFNEDFKKAFQKLVRCRC"
BASE COUNT 493 a 276 c 293 g 492 t
ORIGIN
1 actgttctca ttaaatttct taaataaaaa ggaaaactaa aaccttcaat ctgaacctca
61 tttttttaat ctatagaata ttctgggtaa acataacata cactttttaa aaattattct
121 gaaaggaaga gaaaagttct tgaagccttc tctgaactgt tttttctctt cccttgttac
181 aggtatccat ttttcagcta tattaatctt ttaaaacaaa gaaaatggat ttcttaaatt
241 catctgatca aaacttgacc tcagaggaac tgttaaacag aatgccatcc aaaattctgg
301 tgtccctcac tctgtctggg ctggcactga tgacaacaac tatcaactcc cttgtgatcg
361 ctgcaattat tgtgacccgg aagctgcacc atccagccaa ttatttaatt tgttcccttg
421 cagtcacaga ttttcttgtg gctgtcctgg tgatgccctt cagcattgtg tatattgtga
481 gagagagctg gattatgggg caagtggtct gtgacatttg gctgagtgtt gacattacct
541 gctgcacgtg ctccatcttg catctctcag ctatagcttt ggatcggtat cgagcaatca
601 cagatgctgt tgagtatgcc aggaaaagga ctccaaagca tgctggcatt atgattacaa
661 tagtttggat tatatctgtt tttatctcta tgcctcctct attctggagg caccaaggaa
721 ctagcagaga tgatgaatgc atcatcaagc acgaccacat tgtttccacc atttactcaa
781 catttggagc tttctacatc ccactggcat tgattttgat cctttactac aaaatatata
841 gagcagcaaa gacattatac cacaagagac aagcaagtag gattgcaaag gaggaggtga
901 atggccaagt ccttttggag agtggtgaga aaagcactaa atcagtttcc acatcctatg
961 tactagaaaa gtctttatct gacccatcaa cagactttga taaaattcat agcacagtga
1021 gaagtctcag gtctgaattc aagcatgaga aatcttggag aaggcaaaag atctcaggta
1081 caagagaacg gaaagcagcc actaccctgg gattaatctt gggtgcattt gtaatatgtt
1141 ggcttccttt ttttgtaaaa gaattagttg ttaatgtctg tgacaaatgt aaaatttctg
1201 aagaaatgtc caattttttg gcatggcttg ggtatctcaa ttcccttata aatccactga
1261 tttacacaat ctttaatgaa gacttcaaga aagcattcca aaagcttgtg cgatgtcgat
1321 gttagtttta aaaatgttta ttattgaagg atgggggttt ttgaggggag gaataactag
1381 atgaatgcca aataataaaa cacttaagct tttagaggga aatacatgaa aactgctaaa
1441 ttgataaggc tataatttat attttaatag caatgtgaat ataaaagtta ttgatcacca
1501 ctattctagg gtattcaaaa ttagaaaata atttatgtag gttataacat attt
//