LOCUS HUM5HTTCS 2508 bp mRNA linear HUM 12-JUN-1993
DEFINITION Human Na+/Cl- dependent serotonin transporter mRNA, complete cds.
ACCESSION L05568
VERSION L05568.1
KEYWORDS serotonin transporter.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2508)
AUTHORS Ramamoorthy,S., Bauman,A.L., Moore,K.R., Han,H., Yang-Feng,T.,
Chang,A.S., Ganapathy,V. and Blakely,R.D.
TITLE Antidepressant- and cocaine-sensitive human serotonin transporter:
molecular cloning, expression, and chromosomal localization
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 90 (6), 2542-2546 (1993)
PUBMED 7681602
COMMENT Original source text: Homo sapiens placenta cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2508
/db_xref="H-InvDB:HIT000191681"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="placenta"
CDS 73..1965
/codon_start=1
/product="Na+/Cl- dependent serotonin transporter"
/protein_id="AAA35492.1"
/translation="METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQIS
NGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNV
WRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKG
IGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNI
TWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKT
SGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIF
FSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNE
DVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAV
LDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIE
AVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLF
QYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPETPTEIPCGD
IRLNAV"
BASE COUNT 572 a 652 c 631 g 653 t
ORIGIN
1 caaatccaag cacccagaga tcaattggga tccttggcag atggacatca gtgtcattta
61 ctaaccagca ggatggagac gacgcccttg aattctcaga agcagctatc agcgtgtgaa
121 gatggagaag attgtcagga aaacggagtt ctacagaagg ttgttcccac cccaggggac
181 aaagtggagt ccgggcaaat atccaatggg tactcagcag ttccaagtcc tggtgcggga
241 gatgacacac ggcactctat cccagcgacc accaccaccc tagtggctga gcttcatcaa
301 ggggaacggg agacctgggg caagaaggtg gatttccttc tctcagtgat tggctatgct
361 gtggacctgg gcaatgtctg gcgcttcccc tacatatgtt accagaatgg agggggggca
421 ttcctcctcc cctacaccat catggccatt tttgggggaa tcccgctctt ttacatggag
481 ctcgcactgg gacagtacca ccgaaatgga tgcatttcaa tatggaggaa aatctgcccg
541 attttcaaag ggattggtta tgccatctgc atcattgcct tttacattgc ttcctactac
601 aacaccatca tggcctgggc gctatactac ctcatctcct ccttcacgga ccagctgccc
661 tggaccagct gcaagaactc ctggaacact ggcaactgca ccaattactt ctccgaggac
721 aacatcacct ggaccctcca ttccacgtcc cctgctgaag aattttacac gcgccacgtc
781 ctgcagatcc accggtctaa ggggctccag gacctggggg gcatcagctg gcagctggcc
841 ctctgcatca tgctgatctt cactgttatc tacttcagca tctggaaagg cgtcaagacc
901 tctggcaagg tggtgtgggt gacagccacc ttcccttata tcatcctttc tgtcctgctg
961 gtgaggggtg ccaccctccc tggagcctgg aggggtgttc tcttctactt gaaacccaat
1021 tggcagaaac tcctggagac aggggtgtgg atagatgcag ccgctcagat cttcttctct
1081 cttggtccgg gctttggggt cctgctggct tttgctagct acaacaagtt caacaacaac
1141 tgctaccaag atgccctggt gaccagcgtg gtgaactgca tgacgagctt cgtttcggga
1201 tttgtcatct tcacagtgct cggttacatg gctgagatga ggaatgaaga tgtgtctgag
1261 gtggccaaag acgcaggtcc cagcctcctc ttcatcacgt atgcagaagc gatagccaac
1321 atgccagcgt ccactttctt tgccatcatc ttctttctga tgttaatcac gctgggcttg
1381 gacagcacgt ttgcaggctt ggagggggtg atcacggctg tgctggatga gttcccacac
1441 gtctgggcca agcgccggga gcggttcgtg ctcgccgtgg tcatcacctg cttctttgga
1501 tccctggtca ccctgacttt tggaggggcc tacgtggtga agctgctgga ggagtatgcc
1561 acggggcccg cagtgctcac tgtcgcgctg atcgaagcag tcgctgtgtc ttggttctat
1621 ggcatcactc agttctgcag ggacgtgaag gaaatgctcg gcttcagccc ggggtggttc
1681 tggaggatct gctgggtggc catcagccct ctgtttctcc tgttcatcat ttgcagtttt
1741 ctgatgagcc cgccacaact acgacttttc caatataatt atccttactg gagtatcatc
1801 ttgggttact gcataggaac ctcatctttc atttgcatcc ccacatatat agcttatcgg
1861 ttgatcatca ctccagggac atttaaagag cgtattatta aaagtattac cccagaaaca
1921 ccaacagaaa ttccttgtgg ggacatccgc ttgaatgctg tgtaacacac tcaccgagag
1981 gaaaaaggct tctccacaac ctcctcctcc agttctgatg aggcacgcct gccttctccc
2041 ctccaagtga atgagtttcc agctaagcct gatgatggaa gggccttctc cacagggaca
2101 cagtctggtg cccagactca aggcctccag ccacttattt ccatggattc ccctggacat
2161 attcccatgg tagactgtga cacagctgag ctggcctatt ttggacgtgt gaggatgtgg
2221 atggaggtga tgaaaaccac cctatcatca gttaggatta ggtttagaat caagtctgtg
2281 aaagtctcct gtatcatttc ttggtatgat cattggtatc tgatatctgt ttgcttctaa
2341 aggtttcact gttcatgaat acgtaaactg cgtaggagag aacagggatg ctatctcgct
2401 agccatatat tttctgagta gcatatagaa ttttattgct ggaatctact agaaccttct
2461 aatccatgtg ctgctgtggc atcaggaaag gaagatgtaa gaagctaa
//