LOCUS HUMPPAR 1854 bp mRNA linear HUM 26-JUL-1993
DEFINITION Human peroxisome proliferator activated receptor mRNA, complete
cds.
ACCESSION L02932
VERSION L02932.1
KEYWORDS peroxisome proliferator-activated receptor; steroid receptor
superfamily.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1854)
AUTHORS Sher,T., Yi,H.F., McBride,O.W. and Gonzalez,F.J.
TITLE cDNA cloning, chromosomal mapping, and functional characterization
of the human peroxisome proliferator activated receptor
JOURNAL Biochemistry 32 (21), 5598-5604 (1993)
PUBMED 7684926
COMMENT Original source text: Homo sapiens (library: K19 lambda gt 11)
liver cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..1854
/db_xref="H-InvDB:HIT000191505"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="22q11.2-qter"
/tissue_type="liver"
/tissue_lib="K19 lambda gt 11"
CDS 217..1623
/standard_name="PPAR"
/codon_start=1
/product="peroxisome proliferator activated receptor"
/protein_id="AAA36468.1"
/translation="MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGED
SSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIEC
RICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHK
CLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNF
NMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEVEVRIFHCC
QCTSVETVTELTEFAKAIPAFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAY
GNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLL
NVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKT
ESDAALHPLLQEIYRDMY"
BASE COUNT 499 a 449 c 480 g 426 t
ORIGIN
1 ggcccaggct gaagctcagg gccctgtctg ctctgtggac tcaacagttt gtggcaagac
61 aagctcagaa ctgagaagct gtcaccacag ttctggaggc tgggaagttc aagatcaaag
121 tgccagcaga ttcagtgtca tgtgaggacg tgcttcctgc ttcatagata agagtagctt
181 ggagctcggc ggcacaacca gcaccatctg gtcgcgatgg tggacacgga aagcccactc
241 tgccccctct ccccactcga ggccggcgat ctagagagcc cgttatctga agagttcctg
301 caagaaatgg gaaacatcca agagatttcg caatccatcg gcgaggatag ttctggaagc
361 tttggcttta cggaatacca gtatttagga agctgtcctg gctcagatgg ctcggtcatc
421 acggacacgc tttcaccagc ttcgagcccc tcctcggtga cttatcctgt ggtccccggc
481 agcgtggacg agtctcccag tggagcattg aacatcgaat gtagaatctg cggggacaag
541 gcctcaggct atcattacgg agtccacgcg tgtgaaggct gcaagggctt ctttcggcga
601 acgattcgac tcaagctggt gtatgacaag tgcgaccgca gctgcaagat ccagaaaaag
661 aacagaaaca aatgccagta ttgtcgattt cacaagtgcc tttctgtcgg gatgtcacac
721 aacgcgattc gttttggacg aatgccaaga tctgagaaag caaaactgaa agcagaaatt
781 cttacctgtg aacatgacat agaagattct gaaactgcag atctcaaatc tctggccaag
841 agaatctacg aggcctactt gaagaacttc aacatgaaca aggtcaaagc ccgggtcatc
901 ctctcaggaa aggccagtaa caatccacct tttgtcatac atgatatgga gacactgtgt
961 atggctgaga agacgctggt ggccaagctg gtggccaatg gcatccagaa caaggaggtg
1021 gaggtccgca tctttcactg ctgccagtgc acgtcagtgg agaccgtcac ggagctcacg
1081 gaattcgcca aggccatccc agcgttcgca aacttggacc tgaacgatca agtgacattg
1141 ctaaaatacg gagtttatga ggccatattc gccatgctgt cttctgtgat gaacaaagac
1201 gggatgctgg tagcgtatgg aaatgggttt ataactcgtg aattcctaaa aagcctaagg
1261 aaaccgttct gtgatatcat ggaacccaag tttgattttg ccatgaagtt caatgcactg
1321 gaactggatg acagtgatat ctcccttttt gtggctgcta tcatttgctg tggagatcgt
1381 cctggccttc taaacgtagg acacattgaa aaaatgcagg agggtattgt acatgtgctc
1441 agactccacc tgcagagcaa ccacccggac gatatctttc tcttcccaaa acttcttcaa
1501 aaaatggcag acctccggca gctggtgacg gagcatgcgc agctggtgca gatcatcaag
1561 aagacggagt cggatgctgc gctgcacccg ctactgcagg agatctacag ggacatgtac
1621 tgagttcctt cagatcagcc acaccttttc caggagttct gaagctgaca gcactacaaa
1681 ggagacgggg gagcagcacg attttgcaca aatatccacc actttaacct tagagcttgg
1741 acagtctgag ctgtaggtaa ccggcatatt attccatatc tttgttttaa ccagtacttc
1801 taagagcata gaactcaaat gctgggggag gtggctaatc tcaggactgg gaag
//