LOCUS RATPIT1A 2327 bp mRNA linear ROD 27-APR-1993
DEFINITION Rattus norvegicus PIT-1-alpha (PIT-1) mRNA, complete cds.
ACCESSION L01506
VERSION L01506.1
KEYWORDS DNA-dependent dimerization; POU-homeodomain protein; nuclear
protein; pituitary specific; splice variant; transcriptional
activator.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 2327)
AUTHORS Konzak,K.E. and Moore,D.D.
TITLE Functional isoforms of Pit-1 generated by alternative messenger RNA
splicing
JOURNAL Mol. Endocrinol. 6 (2), 241-247 (1992)
PUBMED 1569967
COMMENT Original source text: Rattus norvegicus (strain Sprague-Dawley)
female pituitary cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..2327
/organism="Rattus norvegicus"
/mol_type="mRNA"
/strain="Sprague-Dawley"
/db_xref="taxon:10116"
/sex="female"
/cell_line="GC3"
/tissue_type="pituitary"
gene 85..960
/gene="PIT-1"
CDS 85..960
/gene="PIT-1"
/codon_start=1
/product="PIT-1-alpha"
/protein_id="AAA41850.1"
/translation="MSCQPFTSADTFIPLNSDASAALPLRMHHSAAEGLPASNHATNV
MSTATGLHYSVPSCHYGNQPSTYGVMAGTLTPCLYKFPDHTLSHGFPPLHQPLLAEDP
TASEFKQELRRKSKLVEEPIDMDSPEIRELEQFANEFKVRRIKLGYTQTNVGEALAAV
HGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRR
TTISIAAKDALERHFGEHSKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSL
NQSLFSISKEHLECR"
CDS 163..960
/gene="PIT-1"
/note="alternate start"
/codon_start=1
/product="PIT-1-alpha"
/protein_id="AAA41851.1"
/translation="MHHSAAEGLPASNHATNVMSTATGLHYSVPSCHYGNQPSTYGVM
AGTLTPCLYKFPDHTLSHGFPPLHQPLLAEDPTASEFKQELRRKSKLVEEPIDMDSPE
IRELEQFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKL
KAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEHSKPSSQEI
MRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR"
BASE COUNT 698 a 480 c 487 g 662 t
ORIGIN
1 gccgtgaatc ggccctttga tacagtaata taataaaagc ggactggcaa gcggtgcgtc
61 ttagttctct actctcttgt gggaatgagt tgccaacctt tcacctcggc tgataccttt
121 atacctctga attctgacgc ttctgctgcc ctgcctctga gaatgcacca cagtgccgct
181 gagggtctcc cagcctccaa ccacgccacc aacgtgatgt ccacagcgac aggacttcat
241 tattctgtgc cttcctgtca ttatggaaac cagccatcca cctacggagt gatggcaggc
301 actttaaccc cttgtcttta caagtttcca gaccacaccc tgagtcatgg gtttcctccc
361 ctgcaccaac ctctgctggc ggaggaccca acagcctctg aatttaagca ggaactcagg
421 cggaaaagta aattggtgga agagccaata gacatggact ccccggaaat ccgagaactg
481 gagcagtttg ccaacgaatt taaagtgaga agaattaagt taggatacac ccagacaaac
541 gtgggcgaag ctctggccgc tgtccacggc tccgaattca gtcaaacaac catctgccga
601 tttgaaaact tgcagctcag tttcaaaaat gcttgcaaac tgaaagcaat tttatccaag
661 tggctggagg aagctgagca ggtcggagct ttgtacaatg aaaaagtggg agcaaacgaa
721 aggaagagga aacggaggac aactatcagt atcgccgcta aggatgcttt ggagagacac
781 tttggagagc acagcaaacc ttcttcgcag gagatcatgc ggatggctga agaattgaat
841 ctcgagaaag aagtagtaag agtgtggttt tgcaaccgaa ggcagagaga aaaacgggtg
901 aaaacgagtc tcaatcaaag tctgttctct atttcaaagg agcatcttga gtgcagataa
961 gacttgcctg tggtagccat gtgtggtagc ctttccattc ctttctgatt tcaagaaaaa
1021 tcagaagtta cttagcttca taaactagat taaatcagca acccctgcag tttttgtttc
1081 actttcttct ttctttccct tttagatcca atgatttaaa acaagacgtt ttatttagtt
1141 gttctcagaa ttcatagcat tgcctttact cctaaatcat caccaagaat gctcacaata
1201 cctcttccaa ttctgccttt atacctaata cacagagagg tggggataac tgggagagag
1261 gccatcatat atgtgaatat tttgagttta aaattacctt ttgtaagtca atttattgtt
1321 ctttaaattt taatcagtaa ggacaaatat ttaccgacta ttaaccaggg atggctcaag
1381 gttgataatc tattgacttg gccagagaga tgtctcagtg gttaagagca tctgttgctc
1441 ttccagagga tgtgggttcc atcacctata cagctcacaa ctgtctgtca cactatttcc
1501 agaggaaatc caaggagtct cctgggttcc attgacactc ggcctgaaaa tgagcacaga
1561 catacatgta gacaaaatac tcatacatat acagtaaaaa taataaatct ataaacaaaa
1621 agaaaatata ttggtttata ctcagtatgc ccctagcact atgttttgtt ttgttttgtt
1681 ttggagtaag gtttgacaat ccagaggtga ctagagacaa ctaagaattt tattaattgc
1741 cttcagaaat aatcttcagt cagaatctat tgatatcttt gacattaaca cttaggacac
1801 gttttttgaa caatttgtag gagcatttag gcatgacatc tgggcgtatt cttttataca
1861 cattagcttt ctgaggctct gctacagaaa acatgtgagc tgcaagctaa acttgctgac
1921 ccaaataatc cttcagtttt ggctttgttt tgttttgttt ggtagtgagt tcaatcctga
1981 gcacaagtga aatttaaaaa tgaaaaatat ggtttaggga tccctaacct atatcataaa
2041 tctgtgtgga agctgcacta gggcgaggct acgtggctta cttgctgtta tgtttccagt
2101 gactgaaaaa gcactggctc ctagtaggta tgtatagacc atgctaaaag gaatgggccc
2161 aatggtgaac aaccgctaca aatatgaagg gtaccaggca acctgaaaaa tctaacttgt
2221 ttttgaagtc tcattgtaga aactcactga ggttccttaa caaagtgtca attttggtct
2281 cactggtcac attttgattt attaataaaa attggaaata tgaaaaa
//