LOCUS HUMCALREC 3588 bp mRNA linear HUM 27-APR-1993
DEFINITION Human calcitonin receptor mRNA, complete cds.
ACCESSION L00587
VERSION L00587.1
KEYWORDS calcitonin; calcitonin receptor; carcinoma; receptor; transmembrane
protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3588)
AUTHORS Gorn,A.H., Lin,H.Y., Yamin,M., Auron,P.E., Flannery,M.R.,
Tapp,D.R., Manning,C.A., Lodish,H.F., Krane,S.M. and Goldring,S.R.
TITLE Cloning, characterization, and expression of a human calcitonin
receptor from an ovarian carcinoma cell line
JOURNAL J. Clin. Invest. 90 (5), 1726-1735 (1992)
PUBMED 1331173
COMMENT Original source text: Homo sapiens cDNA to mRNA.
FEATURES Location/Qualifiers
source 1..3588
/db_xref="H-InvDB:HIT000191433"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="BIN-67"
/cell_type="Ovarian Carcinoma"
mRNA 1..3588
5'UTR 1..247
CDS 248..1720
/codon_start=1
/product="calcitonin receptor"
/protein_id="AAA35640.1"
/translation="MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVG
RKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDF
DPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSI
FTLVISLGIFVFFRKLTTIFPLNWKYRKALSLGCQRVTLHKNMFLTYILNSMIIIIHL
VEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLR
WYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLN
IVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVM
HSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAAAAAE
AGDIPIYICHQEPRNEPANNQGEESAEIIPLNIIEQESSA"
3'UTR 1718..3588
BASE COUNT 1058 a 726 c 720 g 1084 t
ORIGIN
1 gtgcgcacgt ccgcacctca ccctgcggct gacatctcct gcccaggaga tgggcgctga
61 agcttgagcg cctgagtccc tggagccaca cctgcgaaca ccctttgctt ctattgagct
121 gtgcccagcc gcccagtgac agaattccag aataaatgat tcccactgat ccacccactt
181 ttgccacccc aggatgcaat tttctggaga gaagattagt ggacaaagag atcttcaaaa
241 atcaaaaatg aggttcacat ttacaagccg gtgcttggca ctgtttcttc ttctaaatca
301 cccaacccca attcttcctg ccttttcaaa tcaaacctat ccaacaatag agcccaagcc
361 atttctttac gtcgtaggac gaaagaagat gatggatgca cagtacaaat gctatgaccg
421 aatgcagcag ttacccgcat accaaggaga aggtccatat tgcaatcgca cctgggatgg
481 atggctgtgc tgggatgaca caccggctgg agtattgtcc tatcagttct gcccagatta
541 ttttccggat tttgatccat cagaaaaggt tacaaaatac tgtgatgaaa aaggtgtttg
601 gtttaaacat cctgaaaaca atcgaacctg gtccaactat actatgtgca atgctttcac
661 tcctgagaaa ctgaagaatg catatgttct gtactatttg gctattgtgg gtcattcttt
721 gtcaattttc accctagtga tttccctggg gattttcgtg tttttcagaa aattgacaac
781 tatttttcct ttgaattgga aatataggaa ggcattgagc cttggctgcc aaagggtaac
841 cctgcacaag aacatgtttc ttacttacat tctgaattct atgattatca tcatccacct
901 ggttgaagta gtacccaatg gagagctcgt gcgaagggac ccggtgagct gcaagatttt
961 gcattttttc caccagtaca tgatggcctg caactatttc tggatgctct gtgaagggat
1021 ctatcttcat acactcattg tcgtggctgt gtttactgag aagcaacgct tgcggtggta
1081 ttatctcttg ggctgggggt tcccgctggt gccaaccact atccatgcta ttaccagggc
1141 cgtgtacttc aatgacaact gctggctgag tgtggaaacc catttgcttt acataatcca
1201 tggacctgtc atggcggcac ttgtggtcaa tttcttcttt ttgctcaaca ttgtccgggt
1261 gcttgtgacc aaaatgaggg aaacccatga ggcggaatcc cacatgtacc tgaaggctgt
1321 gaaggccacc atgatccttg tgcccctgct gggaatccag tttgtcgtct ttccctggag
1381 accttccaac aagatgcttg ggaagatata tgattacgtg atgcactctc tgattcattt
1441 ccagggcttc tttgttgcga ccatctactg cttctgcaac aatgaggtcc aaaccaccgt
1501 gaagcgccaa tgggcccaat tcaaaattca gtggaaccag cgttggggga ggcgcccctc
1561 caaccgctct gctcgcgctg cagccgctgc tgcggaggct ggcgacatcc caatttacat
1621 ctgccatcag gagccgagga atgaaccagc caacaaccaa ggcgaggaga gtgctgagat
1681 catccctttg aatatcatag agcaagagtc atctgcttga atgtgaagca aacacagtat
1741 cgtgatcact gagccatcat ttcctgggag aaagaccatg catttaaagt attctccatc
1801 ctcccaggaa ccgaacatat catttgtgaa gaattattca gtgaatttgt ccattgtaaa
1861 tctgaagaaa gttattcttg gtactgttgc tttgggagac agtctaggaa tggagtctcc
1921 cactgcaact tgtgaactcc atcattcatc caggactgag atgcaaatgt cacagtaatg
1981 caagcaaagt atcaaagaaa aacaatgaaa ttgacctagt tcagatacag ggtgctcctt
2041 gtcaatactg agccatttat acctttgaaa tattaaaatc actgtcaata tttttatttt
2101 taactctgga ttttgaatta gattatttct gtatttggct atggatctga tttttaattt
2161 ttttaaattt cagtcaattc tgatgttact gagatgtttt accatcctta caatgtaaac
2221 cacatgaact acgtgacctc tgcaagacaa agcggctttc taatagagag attagtaaat
2281 atgtgaagaa aaagacctgc atttggcagg aagatgtatg ctttgaatgc aaaagaaatt
2341 tagagtcaat ttgctgaaaa cattacatgc tcagcttggt tttggacaag cctgtccatt
2401 gggcaggacc tagctgttgt aaagaattgg tcttaatgtt gaatgtattt tggttgctga
2461 tgtttataaa ctgagaggtc acaaagaatc tatcactaaa aatttttaca aaactgccaa
2521 aaatataatt cttagtggaa gacaatactc cctttaaaga aagagagttt gccactcccc
2581 taaactccag gatttataaa gcaaattact ccaaggttta taaagcagat tacctcttgc
2641 ccttgggtgc tatctagcag taaaagataa atttgttgaa tattggtaat taaaagactc
2701 cacataagtc cattaactgc tttccaccca gcttcaaagc ttaaaaagag ctcaggcttt
2761 tccaggaaga tccaggaggg ctaattagaa atcaacttgt ggttgaccgc ttgtttcttg
2821 ttattaccaa aacaggaggg gaaaaaatta actgctccaa atttaaccat aaatcaattc
2881 atgtttaacg tttctcatta aaatccagta ttatattatc atatctctct ttacttccca
2941 gtataagatt tttgaaaatc ctgaataaac cagtatcgtt actggcacct gaaattaatt
3001 tgtgaatttg caacagtaat cagagttacc attatttaat ttgtatgcta aatgaggagg
3061 tacattgaaa ccctccaaat ctccagtctc atctatgtca tattttgcca ctgcctttca
3121 gaagtgattt agttgtggaa agataataaa ttgatttgtt atggttacat attcagcgca
3181 cccagagaaa attaattata tttctacaga gaaaatgaat ttgggatact aaagtagttt
3241 aagtctcctt tactgaatgt aaggggggga tcgaaaagaa ggtatttttc caatcacagt
3301 gttatgtagt attgttctat ttttgtttac aaacatggaa aacagagtat ttctggcagc
3361 tgtggtacaa atgtgataat atattgctaa aatattttag atgttattat gctaatatag
3421 taggggttga agaaaacaaa atagcttatt atagaattgc acatagttct gcccaaatta
3481 tgtgaaatgc ttatgcttgt gtatatgtat aaattaatac agagtacgtt aaaagcaaaa
3541 agatgtatat ttgcatattt ttctaaagaa atatattatt catctttt
//