LOCUS HUMHPAB 1397 bp mRNA linear HUM 08-NOV-1994
DEFINITION Human haptoglobin Hp-alpha-2 mRNA, complete cds.
ACCESSION K00422
VERSION K00422.1
KEYWORDS glycoprotein; haptoglobin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1397)
AUTHORS Yang,F., Brune,J.L., Baldwin,W.D., Barnett,D.R. and Bowman,B.H.
TITLE Identification and characterization of human haptoglobin cDNA
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 80 (19), 5875-5879 (1983)
PUBMED 6310599
COMMENT Original source text: Human adult liver, cDNA to mRNA (library of
K.Matteson and A.Beaudet), clone L6-18.
FEATURES Location/Qualifiers
source 1..1397
/db_xref="H-InvDB:HIT000191350"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="16q22.1"
gene 1..1397
/gene="HP"
mRNA <1..1397
/gene="HP"
/product="hp mRNA"
CDS 13..1233
/gene="HP"
/note="haptoglobin precursor"
/codon_start=1
/protein_id="AAA52687.1"
/db_xref="GDB:G00-119-314"
/translation="MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYV
EHSVRYQCKNYYKLRTEGDGVYTLNNKKQWINKAVGDKLPECEADDGCPKPPEIAHGY
VEHSVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQ
RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIA
PTLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERVMPICLPSKDYAEVG
RVGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPIL
NEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVKV
TSIQDWVQKTIAEN"
sig_peptide 13..66
/gene="HP"
/note="haptoglobin signal peptide"
mat_peptide 67..492
/gene="HP"
/product="haptoglobin alpha-2-chain"
mat_peptide 496..1230
/gene="HP"
/product="haptoglobin beta-chain"
BASE COUNT 395 a 314 c 379 g 309 t
ORIGIN 72 bp upstream of DdeI site.
1 agaccaacca agatgagtgc cctgggagct gtcattgccc tcctgctctg gggacagctt
61 tttgcagtgg actcaggcaa tgatgtcacg gatatcgcag atgacggctg cccgaagccc
121 cccgagattg cacatggcta tgtggagcac tcggttcgct accagtgtaa gaactactac
181 aaactgcgca cagaaggaga tggagtatac accttaaata ataagaagca gtggataaat
241 aaggctgttg gagataaact tcctgaatgt gaagcagatg acggctgccc gaagcccccc
301 gagattgcac atggctatgt ggagcactcg gtccgctacc agtgtaagaa ctactacaaa
361 ctgcgcacag aaggagatgg agtgtacacc ttaaacaatg agaagcagtg gataaataag
421 gctgttggag ataaacttcc tgaatgtgaa gcagtatgtg ggaagcccaa gaatccggca
481 aacccagtgc agcggatcct aggtggacac cttgatgcca aaggcagctt tccctggcag
541 gctaagatgg tttcccacca taatctcacc acaggtgcca cgctgatcaa tgaacaatgg
601 ctgctgacca cggctaaaaa tctcttcctg aaccattcag aaaatgcaac agcgaaagac
661 attgccccta ctttaacact ctatgtgggg aaaaagcagc ttgtagagat tgagaaggtt
721 gttctacacc ctaactactc ccaggtagat attgggctca tcaaactcaa acagaaggtg
781 tctgttaatg agagagtgat gcccatctgc ctaccttcaa aggattatgc agaagtaggg
841 cgtgtgggtt atgtttctgg ctgggggcga aatgccaatt ttaaatttac tgaccatctg
901 aagtatgtca tgctgcctgt ggctgaccaa gaccaatgca taaggcatta tgaaggcagc
961 acagtccccg aaaagaagac accgaagagc cctgtagggg tgcagcccat actgaatgaa
1021 cacaccttct gtgctggcat gtctaagtac caagaagaca cctgctatgg cgatgcgggc
1081 agtgcctttg ccgttcacga cctggaggag gacacctggt atgcgactgg gatcttaagc
1141 tttgataaga gctgtgctgt ggctgagtat ggtgtgtatg tgaaggtgac ttccatccag
1201 gactgggttc agaagaccat agctgagaac taatgcaagg ctggccggaa gcccttgcct
1261 gaaagcaaga tttcagcctg gaagagggca aagtggacgg gagtggacag gagtggatgc
1321 gataagatgt ggtttgaagc tgatgggtgc cagccctgca ttgctgagtc aatcaataaa
1381 gagctttctt ttgaccc
//