LOCUS JQ511984 1615 bp mRNA linear HUM 04-DEC-2012
DEFINITION Homo sapiens cell-line KM-H2 preferentially expressed antigen in
melanoma mRNA, complete cds.
ACCESSION JQ511984
VERSION JQ511984.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1615)
AUTHORS Winkler,C., Steingrube,D.S., Altermann,W., Schlaf,G., Max,D.,
Kewitz,S., Emmer,A., Kornhuber,M., Banning-Eichenseer,U. and
Staege,M.S.
TITLE Hodgkin's lymphoma RNA-transfected dendritic cells induce
cancer/testis antigen-specific immune responses
JOURNAL Cancer Immunol. Immunother. 61 (10), 1769-1779 (2012)
PUBMED 22419371
REFERENCE 2 (bases 1 to 1615)
AUTHORS Kewitz,S. and Staege,M.S.
TITLE Direct Submission
JOURNAL Submitted (26-JAN-2012) Department of Pediatrics,
Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40,
Halle, Sachsen-Anhalt 06120, Germany
FEATURES Location/Qualifiers
source 1..1615
/db_xref="H-InvDB:HIT000721400"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="KM-H2"
/cell_type="Hodgkin's lymphoma"
/note="untreated"
CDS 51..1580
/note="PRAME"
/codon_start=1
/product="preferentially expressed antigen in melanoma"
/protein_id="AFX65486.1"
/translation="MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAA
LELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLD
GLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRK
VDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAM
PMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYI
SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRL
SEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITD
DQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLYPVPLESYED
IHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPILCPCFMP
N"
BASE COUNT 357 a 447 c 420 g 391 t
ORIGIN
1 ctagaaatcc aagcgttgga ggtcctgagg ccagcctaag tcgcttcaaa atggaacgaa
61 ggcgtttgcg gggttccatt cagagccgat acatcagcat gagtgtgtgg acaagcccac
121 ggagacttgt ggagctggca gggcagagcc tgctgaagga tgaggccctg gccattgccg
181 ccctggagtt gctgcccagg gagctcttcc cgccactctt catggcagcc tttgacggga
241 gacacagcca gaccctgaag gcaatggtgc aggcctggcc cttcacctgc ctccctctgg
301 gagtgctgat gaagggacaa catcttcacc tggagacctt caaagctgtg cttgatggac
361 ttgatgtgct ccttgcccag gaggttcgcc ccaggaggtg gaaacttcaa gtgctggatt
421 tacggaagaa ctctcatcag gacttctgga ctgtatggtc tggaaacagg gccagtctgt
481 actcatttcc agagccagaa gcagctcagc ccatgacaaa gaagcgaaaa gtagatggtt
541 tgagcacaga ggcagagcag cccttcattc cagtagaggt gctcgtagac ctgttcctca
601 aggaaggtgc ctgtgatgaa ttgttctcct acctcattga gaaagtgaag cgaaagaaaa
661 atgtactacg cctgtgctgt aagaagctga agatttttgc aatgcccatg caggatatca
721 agatgatcct gaaaatggtg cagctggact ctattgaaga tttggaagtg acttgtacct
781 ggaagctacc caccttggcg aaattttctc cttacctggg ccagatgatt aatctgcgta
841 gactcctcct ctcccacatc catgcatctt cctacatttc cccggagaag gaagagcagt
901 atatcgccca gttcacctct cagttcctca gtctgcagtg cctgcaggct ctctatgtgg
961 actctttatt tttccttaga ggccgcctgg atcagttgct caggcacgtg atgaacccct
1021 tggaaaccct ctcaataact aactgccggc tttcggaagg ggatgtgatg catctgtccc
1081 agagtcccag cgtcagtcag ctaagtgtcc tgagtctaag tggggtcatg ctgaccgatg
1141 taagtcccga gcccctccaa gctctgctgg agagagcctc tgccaccctc caggacctgg
1201 tctttgatga gtgtgggatc acggatgatc agctccttgc cctcctgcct tccctgagcc
1261 actgctccca gcttacaacc ttaagcttct acgggaattc catctccata tctgccttgc
1321 agagtctcct gcagcacctc atcgggctga gcaatctgac ccacgtgctg tatcctgtcc
1381 ccctggagag ttatgaggac atccatggta ccctccacct ggagaggctt gcctatctgc
1441 atgccaggct cagggagttg ctgtgtgagt tggggcggcc cagcatggtc tggcttagtg
1501 ccaacccctg tcctcactgt ggggacagaa ccttctatga cccggagccc atcctgtgcc
1561 cctgtttcat gcctaactag ctgggtgcac atatcaaatg cttcattctg catac
//