LOCUS JQ511983 1633 bp mRNA linear HUM 04-DEC-2012
DEFINITION Homo sapiens cell-line L-540 preferentially expressed antigen in
melanoma mRNA, complete cds.
ACCESSION JQ511983
VERSION JQ511983.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1633)
AUTHORS Winkler,C., Steingrube,D.S., Altermann,W., Schlaf,G., Max,D.,
Kewitz,S., Emmer,A., Kornhuber,M., Banning-Eichenseer,U. and
Staege,M.S.
TITLE Hodgkin's lymphoma RNA-transfected dendritic cells induce
cancer/testis antigen-specific immune responses
JOURNAL Cancer Immunol. Immunother. 61 (10), 1769-1779 (2012)
PUBMED 22419371
REFERENCE 2 (bases 1 to 1633)
AUTHORS Kewitz,S. and Staege,M.S.
TITLE Direct Submission
JOURNAL Submitted (26-JAN-2012) Department of Pediatrics,
Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40,
Halle, Sachsen-Anhalt 06120, Germany
FEATURES Location/Qualifiers
source 1..1633
/db_xref="H-InvDB:HIT000721399"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="L-540"
/cell_type="Hodgkin's lymphoma"
/note="treated with 5AzaC"
CDS 58..1587
/note="PRAME"
/codon_start=1
/product="preferentially expressed antigen in melanoma"
/protein_id="AFX65485.1"
/translation="MERRRLRGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAA
LELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLD
GLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRK
VDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAM
PMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYI
SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRL
SEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITD
DQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLYPVPLESYED
IHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPILCPCFMP
N"
BASE COUNT 363 a 451 c 424 g 395 t
ORIGIN
1 ctgagaccta gaaatccaag cgttggaggt cctgaggcca gcctaagtcg cttcaaaatg
61 gaacgaaggc gtttgcgggg ttccattcag agccgataca tcagcatgag tgtgtggaca
121 agcccacgga gacttgtgga gctggcaggg cagagcctgc tgaaggatga ggccctggcc
181 attgccgccc tggagttgct gcccagggag ctcttcccgc cactcttcat ggcagccttt
241 gacgggagac acagccagac cctgaaggca atggtgcagg cctggccctt cacctgcctc
301 cctctgggag tgctgatgaa gggacaacat cttcacctgg agaccttcaa agctgtgctt
361 gatggacttg atgtgctcct tgcccaggag gttcgcccca ggaggtggaa acttcaagtg
421 ctggatttac ggaagaactc tcatcaggac ttctggactg tatggtctgg aaacagggcc
481 agtctgtact catttccaga gccagaagca gctcagccca tgacaaagaa gcgaaaagta
541 gatggtttga gcacagaggc agagcagccc ttcattccag tagaggtgct cgtagacctg
601 ttcctcaagg aaggtgcctg tgatgaattg ttctcctacc tcattgagaa agtgaagcga
661 aagaaaaatg tactacgcct gtgctgtaag aagctgaaga tttttgcaat gcccatgcag
721 gatatcaaga tgatcctgaa aatggtgcag ctggactcta ttgaagattt ggaagtgact
781 tgtacctgga agctacccac cttggcgaaa ttttctcctt acctgggcca gatgattaat
841 ctgcgtagac tcctcctctc ccacatccat gcatcttcct acatttcccc ggagaaggaa
901 gagcagtata tcgcccagtt cacctctcag ttcctcagtc tgcagtgcct gcaggctctc
961 tatgtggact ctttattttt ccttagaggc cgcctggatc agttgctcag gcacgtgatg
1021 aaccccttgg aaaccctctc aataactaac tgccggcttt cggaagggga tgtgatgcat
1081 ctgtcccaga gtcccagcgt cagtcagcta agtgtcctga gtctaagtgg ggtcatgctg
1141 accgatgtaa gtcccgagcc cctccaagct ctgctggaga gagcctctgc caccctccag
1201 gacctggtct ttgatgagtg tgggatcacg gatgatcagc tccttgccct cctgccttcc
1261 ctgagccact gctcccagct tacaacctta agcttctacg ggaattccat ctccatatct
1321 gccttgcaga gtctcctgca gcacctcatc gggctgagca atctgaccca cgtgctgtat
1381 cctgtccccc tggagagtta tgaggacatc catggtaccc tccacctgga gaggcttgcc
1441 tatctgcatg ccaggctcag ggagttgctg tgtgagttgg ggcggcccag catggtctgg
1501 cttagtgcca acccctgtcc tcactgtggg gacagaacct tctatgaccc ggagcccatc
1561 ctgtgcccct gtttcatgcc taactagctg ggtgcacata tcaaatgctt cattctgcat
1621 acttggacac taa
//