LOCUS JN790819 8375 bp mRNA linear HUM 19-MAR-2013
DEFINITION Homo sapiens PIEZO2 (PIEZO2) mRNA, complete cds.
ACCESSION JN790819
VERSION JN790819.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 8375)
AUTHORS Eijkelkamp,N., Cox,J., Torres,J.M., Sang,H.G. and Wood,J.N.
TITLE A role for Fam38b in mechanical hypersensitivity
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 8375)
AUTHORS Eijkelkamp,N., Cox,J., Torres,J.M., Sang,H.G. and Wood,J.N.
TITLE Direct Submission
JOURNAL Submitted (27-SEP-2011) Wolfson Institute for Biomedical Research,
University College London, Gower Street, London WC1E 6BT, UK
FEATURES Location/Qualifiers
source 1..8375
/db_xref="H-InvDB:HIT000721253"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="dorsal root ganglia"
/PCR_primers="fwd_name: fam38b part 1 fwd, fwd_seq:
ccgacgcgatggcctcagaagt, rev_name: fam38b part 1 rev,
rev_seq: ctgtttgatgggcacatagatctcc"
/PCR_primers="fwd_name: fam38b part 2 fwd, fwd_seq:
ctcctgcttcccatcctcatcttc, rev_name: fam38b part 2 rev,
rev_seq: gaaacaaaccatttccgtcgaactag"
gene 1..8375
/gene="PIEZO2"
CDS 9..8267
/gene="PIEZO2"
/codon_start=1
/product="PIEZO2"
/protein_id="AFC88283.1"
/translation="MASEVVCGLIFRLLLPICLAVACAFRYNGLSFVYLIYLLLIPLF
SEPTKTTMQGHTGRLLKSLCFISLSFLLLHIIFHITLVSLEAQHRIAPGYNCSTWEKT
FRQIGFESLKGADAGNGIRVFVPDIGMFIASLTIWLLCRNIVQKPVTDEAAQSNPEFE
NEELAEGEKIDSEEALIYEEDFNGGDGVEGELEESTKLKMFRRLASVASKLKEFIGNM
ITTAGKVVVTILLGSSGMMLPSLTSSVYFFVFLGLCTWWSWCRTFDPLLFSCLCVLLA
IFTAGHLIGLYLYQFQFFQEAVPPNDYYARLFGIKSVIQTDCSSTWKIIVNPDLSWYH
HANPILLLVMYYTLATLIRIWLQEPLVQDEGTKEEDKALACSPIQITAGRRRSLWYAT
HYPTDERKLLSMTQDDYKPSDGLLVTVNGNPVDYHTIHPSLPMENGPGKADLYSTPQY
RWEPSDESSEKREEEEEEKEEFEEERSREEKRSIKVHAMVSVFQFIMKQSYICALIAM
MAWSITYHSWLTFVLLIWSCTLWMIRNRRKYAMISSPFMVVYGNLLLILQYIWSFELP
EIKKVPGFLEKKEPGELASKILFTITFWLLLRQHLTEQKALQEKEALLSEVKIGSQEN
EEKDEELQDIQVEGEPKEEEEEEAKEEKQERKKVEQEEAEEEDEQDIMKVLGNLVVAM
FIKYWIYVCGGMFFFVSFEGKIVMYKIIYMVLFLFCVALYQVHYEWWRKILKYFWMSV
VIYTMLVLIFIYTYQFENFPGLWQNMTGLKKEKLEDLGLKQFTVAELFTRIFIPTSFL
LVCILHLHYFHDRFLELTDLKSIPSKEDNTIYRLAHPEGSLPDLTMMHLTASLEKPEV
RKLAEPGEEKLEGYSEKAQKGDLGKDSEESEEDGEEEEESEEEEETSDLRNKWHLVID
RLTVLFLKFLEYFHKLQVFMWWILELHIIKIVSSYIIWVSVKEVSLFNYVFLISWAFA
LPYAKLRRLASSVCTVWTCVIIVCKMLYQLQTIKPENFSVNCSLPNENQTNIPFNELN
KSLLYSAPIDPTEWVGLRKSSPLLVYLRNNLLMLAILAFEVTIYRHQEYYRGRNNLTA
PVSRTIFHDITRLHLDDGLINCAKYFINYFFYKFGLETCFLMSVNVIGQRMDFYAMIH
ACWLIAVLYRRRRKAIAEIWPKYCCFLACIITFQYFICIGIPPAPCRDYPWRFKGASF
NDNIIKWLYFPDFIVRPNPVFLVYDFMLLLCASLQRQIFEDENKAAVRIMAGDNVEIC
MNLDAASFSQHNPVPDFIHCRSYLDMSKVIIFSYLFWFVLTIIFITGTTRISIFCMGY
LVACFYFLLFGGDLLLKPIKSILRYWDWLIAYNIFVITMKNILSIGACGYIGTLVHNS
CWLIQAFSLACTVKGYQMPAANSPCTLPSGEAGIIWDSICFAFLLLQRRVFMSYYFLH
VVADIKASQILASRGAELFQATIVKAVKARIEEEKKSMDQLKRQMDRIKARQQKYKKG
KERMLSLTQEPGEGQDMQKLSEEDDEREADKQKAKGKKKQWWRPWVDHASMVRSGDYY
LFETDSEEEEEEELKKEDEEPPRRSAFQFVYQAWITDPKTALRQRHKEKKRSAREERK
RRRKGSKEGPVEWEDREDEPIKKKSDGPDNIIKRIFNILKFTWVLFLATVDSFTTWLN
SISREHIDISTVLRIERCMLTREIKKGNVPTRESIHMYYQNHIMNLSRESGLDTIDEH
PGAASGAQTAHRMDSLDSHDSISSEPTQCTMLYSRQGTTETIEEVEAEQEEEAGSTAP
EPREAKEYEATGYDVGAMGAEEASLTPEEELTQFSTLDGDVEAPPSYSKAVSFEHLSF
GSQDDSAGKNRMAVSPDDSRTDKLGSSILPPLTHELTASELLLKKMFHDDELEESEKF
YVGQPRFLLLFYAMYNTLVARSEMVCYFVIILNHMVSASMITLLLPILIFLWAMLSVP
RPSRRFWMMAIVYTEVAIVVKYFFQFGFFPWNKNVEVNKDKPYHPPNIIGVEKKEGYV
LYDLIQLLALFFHRSILKCHGLWDEDDMTESGMAREESDDELSLGHGRRDSSDSLKSI
NLAASVESVHVTFPEQQTAVRRKRSGSSSEPSQRSSFSSNRSQRGSTSTRNSSQKGSS
VLSIKQKGKRELYMEKLQEHLIKAKAFTIKKTLEIYVPIKQFFYNLIHPEYSAVTDVY
VLMFLADTVDFIIIVFGFWAFGKHSAAADITSSLSEDQVPGPFLVMVLIQFGTMVVDR
ALYLRKTVLGKVIFQVILVFGIHFWMFFILPGVTERKFSQNLVAQLWYFVKCVYFGLS
AYQIRCGYPTRVLGNFLTKSYNYVNLFLFQGFRLVPFLTELRAVMDWVWTDTTLSLSS
WICVEDIYAHIFILKCWRESEKRYPQPRGQKKKKVVKYGMGGMIIVLLICIVWFPLLF
MSLIKSVAGVINQPLDVSVTITLGGYQPIFTMSAQQSQLKIMDQQSFNKFIQAFSRDT
GAMQFLENYEKEDITVAELEGNSNSLWTISPPSKQKMIHELLDPNSSFSVVFSWSIQR
NLSLGAKSEIATDKLSFPLKNITRKNIAKMIAGNSTESSKTPVTIEKIYPYYVKAPSD
SNSKPIKQLLSENNFMDITIILSRDNTTKYNSEWWVLNLTGNRIYNPNSQALELVVFN
DKVSPPSLGFLAGYGIMGLYASVVLVIGKFVREFFSGISHSIMFEELPNVDRILKLCT
DIFLVRETGELELEEDLYAKLIFLYRSPETMIKWTREKTN"
BASE COUNT 2302 a 1907 c 2032 g 2134 t
ORIGIN
1 ccgacgcgat ggcctcagaa gtggtgtgcg ggctcatctt caggctgctg ctgcccatct
61 gcctggcagt agcatgtgca ttccgataca atgggctctc ctttgtctac cttatctacc
121 tcttgctcat tcctctgttc tcagaaccaa caaaaacgac gatgcaagga catacgggac
181 ggttattaaa gtctctgtgc ttcatcagtc tttccttcct gttgctgcac atcattttcc
241 acatcacgtt ggtgagcctt gaagctcaac atcgtattgc acctggctac aactgctcaa
301 catgggaaaa gacattccgg cagatcggct ttgaaagctt aaagggagct gatgctggca
361 atgggatcag agtgtttgta cctgacatcg ggatgttcat tgctagtctg accatctggc
421 tcctctgtag aaacattgtt cagaaacctg tgacagacga agcagcacag agtaacccgg
481 agtttgaaaa tgaagaattg gctgaaggag aaaaaattga ttcagaagag gcactgatct
541 atgaagagga tttcaatgga ggagatggtg ttgaaggcga gttggaagaa agcacgaagt
601 taaaaatgtt ccgcaggctt gcctctgtgg cctctaagct caaggagttc attggcaaca
661 tgatcaccac tgctgggaaa gtcgttgtta ccatcttact gggctcctcg ggcatgatgt
721 tgccatcttt gacatcatct gtgtattttt ttgtattttt gggtctgtgc acctggtggt
781 cctggtgccg gacgttcgac ccattgctgt tcagctgtct ctgtgttctg ctggctattt
841 tcactgctgg acatttgatt ggactttatt tataccagtt ccaattcttt caagaggcag
901 ttccacccaa tgactactat gcaaggttgt ttggtatcaa gtcagtaatt caaacggact
961 gttcaagtac ttggaagatc atagtgaacc cggacctgtc gtggtaccac cacgccaacc
1021 ctatcctcct gctggtgatg tactacactc tggccactct gatccgcatc tggctgcaag
1081 agccccttgt gcaggatgag gggaccaaag aagaggacaa agccctggct tgtagcccca
1141 tccaaataac agcggggagg aggcggagcc tgtggtacgc aacccattac cccactgatg
1201 agagaaaact tttatccatg acccaggatg actacaaacc atctgatggc ctgctggtga
1261 ctgtgaacgg caaccccgtg gattaccaca ccatccaccc aagcctgccc atggagaacg
1321 gccctggcaa agccgacctc tactccaccc ctcagtaccg gtgggagccc tctgatgaat
1381 cctcagaaaa gcgagaggag gaagaggaag agaaagaaga atttgaagaa gaaaggagcc
1441 gtgaggaaaa aagaagtatc aaagttcatg ccatggtctc cgtattccaa tttattatga
1501 aacaaagtta catctgtgcc ctcatagcta tgatggcctg gagcatcacc tatcacagct
1561 ggctgacctt cgtgctgctg atctggtcgt gcactctttg gatgattcgc aacagaagaa
1621 aatatgccat gatcagctct cccttcatgg tggtttatgg aaacctattg ttgatattac
1681 agtatatatg gagttttgaa cttcctgaaa ttaaaaaagt tccaggattt ttagaaaaga
1741 aagagccagg agaacttgct tccaaaatcc ttttcaccat tactttttgg ctactgctga
1801 ggcagcacct cacagagcaa aaagctctgc aagaaaagga agctctttta tcggaagtca
1861 aaattggcag tcaggaaaat gaagaaaaag atgaggaact tcaagatata caagtggaag
1921 gagagcccaa agaggaggaa gaagaggaag cgaaggaaga gaagcaagag agaaagaagg
1981 tagagcaaga ggaagctgaa gaagaagatg agcaggacat catgaaagtc ctgggcaatc
2041 tggtggtggc catgttcatc aagtactgga tctacgtctg cggaggcatg ttcttcttcg
2101 tcagcttcga gggtaaaatc gtaatgtaca aaatcatcta catggtgctg ttcctgttct
2161 gtgtggccct ataccaggtg cactatgaat ggtggaggaa aattctaaaa tatttttgga
2221 tgtcagtggt tatttacact atgctggtgc ttatctttat atacacatat cagtttgaga
2281 acttcccagg cctgtggcaa aatatgactg gattgaaaaa agaaaagctt gaggatcttg
2341 gcttaaagca gtttactgtg gctgaactat tcactcgcat attcatccca acctcctttc
2401 tgctggtgtg cattttacac ctgcactact tccatgaccg gttccttgaa ctcacagacc
2461 tcaagtccat tcccagcaaa gaagacaaca ccatctacag actggcccac ccggaaggaa
2521 gcctcccgga cctcaccatg atgcatctga ctgccagcct ggagaagccg gaggtgagga
2581 agttggctga gcctggggag gagaagcttg agggctactc tgaaaaagcc cagaagggtg
2641 atcttgggaa agacagcgag gagtcagagg aggacggaga ggaagaggag gaatccgagg
2701 aggaggaaga aacatcagac ttaaggaaca aatggcacct ggtgattgac cgcctcactg
2761 tgctcttctt aaaattcctg gagtattttc acaagctgca ggtgttcatg tggtggattt
2821 tggagttgca catcatcaaa atcgtttcct cttacattat ctgggtttct gtgaaagagg
2881 tgtctctgtt caactatgta tttttgattt cttgggcttt tgctctgccg tacgccaagc
2941 tgcgccgtct ggcttcaagt gtctgcacgg tctggacgtg tgtgatcatc gtctgcaaaa
3001 tgttgtacca gcttcaaacc attaagcctg agaacttctc tgttaactgt tccttgccaa
3061 atgaaaatca aacaaacatc ccctttaatg agttgaacaa gtctctgctc tacagcgctc
3121 ctatcgatcc tacagagtgg gtcggcctgc ggaagtcttc gcctctgcta gtctacctga
3181 ggaataacct cctgatgctg gctatcctgg cctttgaagt caccatttac cgccatcagg
3241 aatactatcg aggtcgaaat aacctgacgg cccctgtgtc tagaactatc tttcatgaca
3301 ttacaagact acatctagat gatggactta ttaattgtgc caaatatttc attaattact
3361 tcttttacaa gtttggtctg gagacctgtt tcctaatgtc agttaacgtc attggccagc
3421 gaatggattt ctatgccatg atccacgcct gctggctgat cgctgtctta tatagacgca
3481 gaaggaaagc catcgcagag atctggccca agtactgctg cttcctggca tgcatcatca
3541 ccttccagta tttcatctgc attggcatcc cacctgctcc ttgccgagat tacccgtgga
3601 gattcaaggg tgccagcttc aatgacaaca tcataaagtg gctgtacttc ccagatttca
3661 ttgtgcggcc caaccctgtg tttctcgtct atgacttcat gctgcttctg tgtgcctcct
3721 tacaacggca gatttttgag gatgagaaca aggctgcagt gcgaatcatg gcaggtgaca
3781 atgtcgagat ctgcatgaat cttgatgcgg cctccttcag ccaacataac cctgtgccag
3841 attttattca ctgcagatct tacttagaca tgtccaaagt gatcatcttc agctacctct
3901 tctggtttgt gctcaccatc atcttcatca ctgggaccac caggatcagc atcttttgca
3961 tggggtacct ggtggcctgt ttctacttcc tgctctttgg gggcgatttg ctgttgaaac
4021 ccatcaagag catcctgcgc tactgggact ggctgatcgc atacaacatt tttgtgatta
4081 cgatgaaaaa tatcctgtca ataggagcat gtggatacat tggaacattg gtgcacaata
4141 gttgttggtt gatccaggct ttcagcctgg cctgcacagt caaaggctat caaatgcctg
4201 ctgctaattc accctgtaca ctacccagtg gggaagcagg aatcatttgg gacagcatat
4261 gttttgcctt cctcctgctg caaagaagag ttttcatgag ttattatttt ctacatgttg
4321 tggctgatat aaaagcttcc cagattctgg catcaagagg agctgaactt ttccaggcca
4381 caattgtaaa agctgtaaag gcaagaattg aggaagagaa gaagtccatg gaccagctga
4441 agcgacagat ggatcgcatc aaggccaggc aacagaaata taaaaagggt aaggagagga
4501 tgctgagctt gacccaggag ccaggggaag gccaggacat gcaaaaactc tctgaagagg
4561 atgatgaaag agaagcagac aaacagaaag ccaagggcaa aaaaaagcag tggtggcggc
4621 cttgggttga tcatgcttcc atggtcagga gtggagatta ttatttgttt gaaacggata
4681 gtgaagagga ggaagaggaa gaattaaaga aggaagatga agaacctcca cgaaggtcag
4741 cattccagtt tgtttatcaa gcctggatta ctgatcctaa aacagcactc cgacaaagac
4801 acaaagagaa aaaaaggtct gcaagagaag aacggaaacg aaggcggaaa ggatccaagg
4861 agggtcctgt ggaatgggaa gaccgggagg atgaaccaat caaaaagaaa tccgatggac
4921 cagataatat catcaagagg atatttaata ttttgaaatt tacctgggtc ctatttctgg
4981 caacagtgga cagtttcact acttggctta actccatttc aagggagcat attgatatat
5041 ctacagttct gagaattgaa cgatgcatgc tgaccagaga aattaagaag ggcaatgttc
5101 caactcggga gagcatccac atgtactatc agaaccacat catgaacctt tccagagagt
5161 cgggactgga caccattgac gagcatcccg gagctgcttc aggtgcacag acagcccaca
5221 ggatggatag tttagattca catgacagta tctccagcga gcccacgcag tgtaccatgc
5281 tgtactcacg ccaggggacc actgagacca tcgaggaggt ggaggctgag caggaggagg
5341 aggcagggag cacggcgcct gagcccaggg aggccaagga gtacgaggcc actgggtacg
5401 atgtgggagc catgggtgcc gaggaggcca gcctcacccc agaggaagag ctgacacagt
5461 tctccacctt ggacggggat gtggaggccc caccctccta cagcaaggct gtgagcttcg
5521 agcatctgtc cttcggctcg caggacgact ctgcaggcaa gaaccgtatg gcagtcagcc
5581 cggacgacag ccgcaccgac aagctggggt ccagcatctt acctcccctg acccatgagc
5641 tgacggccag cgagctgctg ctgaaaaaga tgtttcacga cgatgagctt gaagagtcag
5701 agaaattcta cgtggggcag ccccgatttc tgctgctctt ctatgccatg tacaataccc
5761 tggtggcccg ctcggagatg gtgtgctact tcgtgatcat cctcaaccac atggtctctg
5821 cctccatgat cacgctcctg cttcccatcc tcatcttcct ctgggccatg ttgtccgtcc
5881 ccaggcccag ccgccggttc tggatgatgg ccatcgtcta tactgaggtg gcaattgtag
5941 tcaagtattt cttccaattt gggttctttc cctggaataa gaatgtggag gtgaacaaag
6001 ataaaccgta tcacccccca aacatcatag gagtggaaaa gaaggaaggt tatgttctct
6061 atgacctcat ccagctcctg gctctgttct ttcatcgatc aattttgaag tgccatggct
6121 tatgggatga agatgacatg actgaaagtg gcatggccag ggaggaatca gatgatgagc
6181 tctccctcgg tcatggcagg agggactcct ccgattctct caagtccatc aacctggccg
6241 cgtctgtgga gtcagtgcat gtgacctttc cggagcagca gacagctgtc cggaggaagc
6301 gctccggcag cagctccgag ccatcccaga gatccagctt ttcttcaaac agatcccaaa
6361 gaggcagcac aagcacccga aacagcagtc aaaaaggaag cagtgttttg agtattaagc
6421 aaaaaggcaa aagggaactt tatatggaaa agcttcaaga acatttaatc aaagcaaaag
6481 cctttaccat aaagaagacg ctggagatct atgtgcccat caaacagttc ttttacaacc
6541 tcatccaccc ggagtatagc gccgtgactg acgtgtatgt actcatgttc ctggctgaca
6601 ctgtggactt catcatcatt gtcttcggct tttgggcctt tgggaaacac tcagcagctg
6661 cagacatcac ctcttcactg tcagaggacc aggtcccggg gccgtttttg gtgatggtcc
6721 tcattcagtt tggaaccatg gtggtggacc gagccctcta cctcaggaag actgtactgg
6781 gaaaggtcat cttccaggtc attcttgtgt tcggaattca cttctggatg ttcttcatct
6841 tacctggtgt gactgagagg aaattcagcc agaacctggt tgcccagctt tggtactttg
6901 tgaaatgtgt ttacttcggg ttgtctgctt accagatccg ttgtggctac ccaacgcgag
6961 tcctggggaa cttcctcacc aagagctaca attacgtcaa cctcttctta ttccaagggt
7021 ttcgcctcgt gccctttttg actgagctga gggcagtgat ggactgggtg tggacggaca
7081 caactttgag cctgtccagc tggatctgtg tggaggacat ctatgctcac atattcatcc
7141 tgaagtgttg gcgggagtcg gagaagagat accctcagcc acggggccag aagaagaaga
7201 aagtggtgaa gtatggcatg ggaggaatga tcatcgtcct gctcatctgc attgtctggt
7261 ttcctcttct cttcatgtct ttgatcaaat ctgtggctgg ggtcatcaac cagcccctgg
7321 acgtctccgt cacaattacc ctgggagggt atcagcctat tttcacaatg agtgcccaac
7381 aaagccagtt gaaaattatg gaccagcaga gctttaacaa atttatacaa gctttttcta
7441 gggacaccgg tgctatgcaa tttctggaaa attatgaaaa agaagacata acagtagcag
7501 aactggaagg aaactcaaat tctttgtgga ccatcagccc acccagtaag cagaaaatga
7561 tacacgaact cctggacccc aatagtagct tctctgttgt tttttcatgg agtattcaga
7621 gaaacttaag tctgggtgca aaatcggaaa tagcaacaga taagctttct tttcctctta
7681 aaaatattac tcgaaagaat atcgctaaaa tgatagcagg caacagcaca gaaagttcaa
7741 aaacaccagt gaccatagaa aagatttatc catattatgt gaaagcacct agtgattcta
7801 actcaaaacc tataaagcaa cttttatctg aaaataattt catggatatt accatcattt
7861 tgtccagaga caatacaact aaatataaca gtgagtggtg ggttctcaac ctgactggaa
7921 acagaatata caatccgaac tctcaggccc tggaactggt ggtcttcaat gacaaagtca
7981 gtcccccaag tctggggttc ctggctggct atggtattat gggattatat gcttcagttg
8041 tccttgtgat tgggaaattt gtccgtgaat tcttcagtgg gatttctcac tccatcatgt
8101 ttgaagagct tccaaatgtg gatcgaattt tgaagttgtg cacagatatt tttttagttc
8161 gagagacagg agaactggag ctagaagaag atctctatgc caaattaata ttcctatatc
8221 gctcaccaga gacaatgatc aaatggacta gagaaaaaac aaattgaaac cttagaacac
8281 agactgcaaa taatgttaac atttgaattt tttttaaaag cacaatattc tcataagagc
8341 taagcatttc tagttcgacg gaaatggttt gtttc
//