LOCUS HUMMUCAB 1804 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human polymorphic epithelial mucin (PEM) mRNA, complete cds.
ACCESSION J05581
VERSION J05581.1
KEYWORDS polymorphic epithelial mucin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1804)
AUTHORS Gendler,S.J., Lancaster,C.A., Taylor-Papadimitriou,J., Duhig,T.,
Peat,N., Burchell,J., Pemberton,L., Lalani,E.N. and Wilson,D.
TITLE Molecular cloning and expression of human tumor-associated
polymorphic epithelial mucin
JOURNAL J. Biol. Chem. 265 (25), 15286-15293 (1990)
PUBMED 1697589
COMMENT Original source text: Homo sapiens adult adenocarcinoma cDNA to
mRNA.
Draft entry and computer-readable sequence for [J. Biol. Chem.
(1990) In press] kindly submitted
by S.J.Gendler, 26-JUN-1990.
FEATURES Location/Qualifiers
source 1..1804
/db_xref="H-InvDB:HIT000191341"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="Xq26.3-q27.1"
/cell_line="BT20"
/tissue_type="adenocarcinoma"
/dev_stage="adult"
gene 1..1804
/gene="MCNAA"
mRNA <1..1804
/gene="MCNAA"
/product="PEM mRNA"
CDS 73..1500
/gene="MCNAA"
/codon_start=1
/product="polymorphic epithelial mucin"
/protein_id="AAA59876.1"
/translation="MTPGTQSPFFLLLLLTVLTVVTGSGHASSTPGGEKETSATQRSS
VPSSTEKNAVSMTSSVLSSHSPGSGSSTTQGQDVTLAPATEPASGSAATWGQDVTSVP
VTRPALGSTTPPAHDVTSAPDNKPAPGSTAPPAHGVTSAPDTRPAPGSTAPPAHGVTS
APDNRPALGSTAPPVHNVTSASGSASGSASTLVHNGTSARATTTPASKSTPFSIPSHH
SDTPTTLASHSTKTDASSTHHSTVPPLTSSNHSTSPQLSTGVSFFFLSFHISNLQFNS
SLEDPSTDYYQELQRDISEMFLQIYKQGGFLGLSNIKFRPGSVVVQLTLAFREGTINV
HDVETQFNQYKTEAASRYNLTISDVSVSDVPFPFSAQSGAGVPGWGIALLVLVCVLVA
LAIVYLIALAVCQCRRKNYGQLDIFPARDTYHPMSEYPTYHTHGRYVPPSSTDRSPYE
KVSAGNGGSSLSYTNPAVAATSANL"
sig_peptide 73..135
/gene="MCNAA"
mat_peptide 136..1497
/gene="MCNAA"
/product="polymorphic epithelial mucin"
regulatory 1783..1788
/regulatory_class="polyA_signal_sequence"
/gene="MCNAA"
BASE COUNT 361 a 622 c 434 g 387 t
ORIGIN
1 cgctccacct ctcaagcagc cagcgcctgc ctgaatctgt tctgccccct ccccacccat
61 ttcaccacca ccatgacacc gggcacccag tctcctttct tcctgctgct gctcctcaca
121 gtgcttacag ttgttacagg ttctggtcat gcaagctcta ccccaggtgg agaaaaggag
181 acttcggcta cccagagaag ttcagtgccc agctctactg agaagaatgc tgtgagtatg
241 accagcagcg tactctccag ccacagcccc ggttcaggct cctccaccac tcagggacag
301 gatgtcactc tggccccggc cacggaacca gcttcaggtt cagctgccac ctggggacag
361 gatgtcacct cggtcccagt caccaggcca gccctgggct ccaccacccc gccagcccac
421 gatgtcacct cagccccgga caacaagcca gccccgggct ccaccgcccc cccagcccac
481 ggtgtcacct cggccccgga caccaggccg gccccgggct ccaccgcccc cccagcccat
541 ggtgtcacct cggccccgga caacaggccc gccttgggct ccaccgcccc tccagtccac
601 aatgtcacct cggcctcagg ctctgcatca ggctcagctt ctactctggt gcacaacggc
661 acctctgcca gggctaccac aaccccagcc agcaagagca ctccattctc aattcccagc
721 caccactctg atactcctac cacccttgcc agccatagca ccaagactga tgccagtagc
781 actcaccata gcacggtacc tcctctcacc tcctccaatc acagcacttc tccccagttg
841 tctactgggg tctctttctt tttcctgtct tttcacattt caaacctcca gtttaattcc
901 tctctggaag atcccagcac cgactactac caagagctgc agagagacat ttctgaaatg
961 tttttgcaga tttataaaca agggggtttt ctgggcctct ccaatattaa gttcaggcca
1021 ggatctgtgg tggtacaatt gactctggcc ttccgagaag gtaccatcaa tgtccacgac
1081 gtggagacac agttcaatca gtataaaacg gaagcagcct ctcgatataa cctgacgatc
1141 tcagacgtca gcgtgagtga tgtgccattt cctttctctg cccagtctgg ggctggggtg
1201 ccaggctggg gcatcgcgct gctggtgctg gtctgtgttc tggttgcgct ggccattgtc
1261 tatctcattg ccttggctgt ctgtcagtgc cgccgaaaga actacgggca gctggacatc
1321 tttccagccc gggataccta ccatcctatg agcgagtacc ccacctacca cacccatggg
1381 cgctatgtgc cccctagcag taccgatcgt agcccctatg agaaggtttc tgcaggtaat
1441 ggtggcagca gcctctctta cacaaaccca gcagtggcag ccacttctgc caacttgtag
1501 gggcacgtcg cccgctgagc tgagtggcca gccagtgcca ttccactcca ctcaggttct
1561 tcagggccag agcccctgca ccctgtttgg gctggtgagc tgggagttca ggtgggctgc
1621 tcacaccgtc cttcagaggc cccaccaatt tctcggacac ttctcagtgt gtggaagctc
1681 atgtgggccc ctgaggctca tgcctgggaa gtgttgtggt gggggctccc aggaggactg
1741 gcccagagag ccctgagata gcggggatcc tgaactggac tgaataaaac gtggtctccc
1801 actg
//