LOCUS HUMMRA 5185 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human mannose receptor mRNA, complete cds.
ACCESSION J05550
VERSION J05550.1
KEYWORDS mannose receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5185)
AUTHORS Taylor,M.E., Conary,J.T., Lennartz,M.R., Stahl,P.D. and
Drickamer,K.
TITLE Primary structure of the mannose receptor contains multiple motifs
resembling carbohydrate-recognition domains
JOURNAL J. Biol. Chem. 265 (21), 12156-12162 (1990)
PUBMED 2373685
COMMENT Original source text: Human placenta, cDNA to mRNA.
Draft entry and computer-readable sequence for [1] kindly submitted
by K.Drickamer, 18-MAY-1990.
FEATURES Location/Qualifiers
source 1..5185
/db_xref="H-InvDB:HIT000191339"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="12"
gene 1..5185
/gene="M6PR"
CDS 104..4474
/gene="M6PR"
/note="mannose receptor precursor"
/codon_start=1
/protein_id="AAA59868.1"
/db_xref="GDB:G00-120-162"
/translation="MRLPLLLVFASVIPGAVLLLDTRQFLIYNEDHKRCVDAVSPSAV
QTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWEC
KNDTLLGIKGEDLFFNYGNRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLL
GNANGATCAFPFKFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSES
LWNKDPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSG
LWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQ
KLGYICKKGNTTLNSFVIPSESDVPTHCPSQWWPYAGHCYKIHRDEKKIQRDALTTCR
KEGGDLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLR
GEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMKSRSQGPEIVEVEKGCRKGW
KKHHFYCYMIGHTLSTFAEANQTCNNENAYLTTIEDRYEQAFLTSFVGLRPEKYFWTG
LSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGCVAMRTGIAGGLWDVLKCDEKAKFV
CKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRA
LGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWA
YGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQDNPP
VTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQSESEKKFLWKYVNRNDA
QSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINC
GYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKNWQE
ARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTFLWTDGRGVHY
TNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQTRSDPSLT
NPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWLQM
ETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWKTAHC
NESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQASLE
CLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNW
NTGDPSGERNDCVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLTTKADTRK
MDPSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNSQSSP
GTSDMKDLVGNIEQNEHSVI"
sig_peptide 104..157
/gene="M6PR"
/note="mannose receptor signal peptide"
mat_peptide 158..4471
/gene="M6PR"
/product="mannose receptor"
BASE COUNT 1602 a 999 c 1198 g 1386 t
ORIGIN
1 gggaacttgg attaggtgga gaggcagttg gggggcctcg ttgttttgcg tcttagttcc
61 gccctcctgt ccatcaggag aaggaaagga taaaccctgg gccatgaggc tacccctgct
121 cctggttttt gcctctgtca ttccgggtgc tgttctccta ctggacacca ggcaattttt
181 aatctataat gaagatcaca agcgctgcgt ggatgcagtg agtcccagtg ccgtccaaac
241 cgcagcttgc aaccaggatg ccgaatcaca gaaattccga tgggtgtccg aatctcagat
301 tatgagtgtt gcatttaaat tatgcctggg agtgccatca aaaacagact gggttgctat
361 cactctctat gcctgtgact caaaaagtga atttcagaaa tgggagtgca aaaatgacac
421 acttttgggg atcaaaggag aagatttatt ttttaactac ggcaacagac aagaaaagaa
481 tattatgctc tacaagggat cgggtttatg gagcaggtgg aagatctatg gaaccacaga
541 caatctgtgc tccagaggtt atgaagccat gtatacgcta ctaggcaatg ccaatggagc
601 aacctgtgca ttcccgttca agtttgaaaa caagtggtac gcagattgca cgagtgctgg
661 gcggtcggat ggatggctct ggtgcggaac cactactgac tatgacacag acaagctatt
721 tggatattgt ccattgaaat ttgagggcag tgaaagctta tggaataaag acccgctgac
781 cagcgtttcc taccagataa actccaaatc cgctttaacg tggcaccaag cgaggaaaag
841 ctgccaacaa cagaacgctg agctcctgag catcacagag atacatgagc aaacatacct
901 gacaggatta accagttcct tgacctcagg actctggatt ggacttaaca gtctgagctt
961 caacagcggt tggcagtgga gtgaccgcag tcctttccga tatttgaact ggttaccagg
1021 aagtccatca gctgaacctg gaaaaagctg tgtgtcacta aatcctggaa aaaatgctaa
1081 atgggaaaat ctggaatgtg ttcagaaact gggctatatt tgcaaaaagg gcaacaccac
1141 tttaaattct tttgttattc cctcagaaag tgatgtgcct actcactgtc ctagtcagtg
1201 gtggccgtat gccggtcact gttacaagat tcacagagat gagaaaaaaa tccagaggga
1261 tgctctgacc acctgcagga aggaaggcgg tgacctcaca agtatccaca ccatcgagga
1321 attggacttt attatctccc agctaggata tgagccaaat gacgaattgt ggatcggctt
1381 aaatgacatt aagattcaaa tgtactttga gtggagtgat gggacccctg taacgtttac
1441 caaatggctt cgtggagaac caagccatga aaacaacaga caggaggatt gtgtggtgat
1501 gaaaggcaag gatgggtact gggcagatcg gggctgtgag tggcctcttg gctacatctg
1561 caagatgaaa tcacgaagcc aaggtccaga aatagtggaa gtcgaaaaag gctgcaggaa
1621 aggctggaaa aaacatcact tttactgcta tatgattgga catacgcttt caacatttgc
1681 agaagcaaac caaacctgta ataatgagaa tgcttattta acaactattg aagacagata
1741 tgaacaagcc ttcctgacta gtttcgttgg cttaaggcct gaaaaatatt tctggacagg
1801 actttcagat atacaaacca aagggacttt tcagtggacc atcgaggaag aggttcggtt
1861 cacccactgg aattcagata tgccagggcg aaagccaggg tgtgttgcca tgagaaccgg
1921 gattgcaggg ggcttatggg atgttttgaa atgtgatgaa aaggcaaaat ttgtgtgcaa
1981 gcactgggca gaaggagtaa cccacccacc gaagcccacg acgactcccg aacccaaatg
2041 tccggaggat tggggcgcca gcagtagaac aagcttgtgt ttcaagctgt atgcaaaagg
2101 aaaacatgag aagaaaacgt ggtttgaatc tcgagatttt tgtcgagctc tgggtggaga
2161 cttagctagc atcaataaca aagaggaaca gcaaacaata tggcgattaa taacagctag
2221 tggaagctac cacaaactgt tttggttggg attgacatat ggaagccctt cagaaggttt
2281 tacttggagt gatggttctc ctgtttcata tgaaaactgg gcttatggag aacctaataa
2341 ttatcaaaat gttgaatact gtggtgagct gaaaggtgac cctactatgt cttggaatga
2401 tattaattgt gaacacctta acaactggat ttgccagata caaaaaggac aaacaccaaa
2461 acctgagcca acaccagctc ctcaagacaa tccaccagtt actgaagatg ggtgggttat
2521 ttacaaagac taccagtatt atttcagcaa agagaaggaa accatggaca atgcgcgagc
2581 gttttgcaag aggaattttg gtgatcttgt ttctattcaa agtgaaagtg aaaagaagtt
2641 tctatggaaa tatgtaaaca gaaatgatgc acagtctgca tattttattg gtttattgat
2701 cagcttggat aaaaagtttg cttggatgga tggaagcaaa gtggattacg tgtcttgggc
2761 cacaggtgaa cccaattttg caaatgaaga tgaaaactgt gtgaccatgt attcaaattc
2821 agggttttgg aatgacatta actgtggcta tccaaacgcc ttcatttgcc agcgacataa
2881 cagtagtatc aatgctacca cagttatgcc taccatgccc tcggtcccat cagggtgcaa
2941 ggaaggttgg aatttctaca gcaacaagtg tttcaaaatc tttggattta tggaagaaga
3001 aagaaaaaat tggcaagagg cacgaaaagc ttgtataggc tttggaggga atctggtctc
3061 catacaaaat gaaaaagagc aagcatttct tacctatcac atgaaggact ccactttcag
3121 tgcctggact gggctgaatg atgtcaattc agaacacacg ttcctttgga cggatggacg
3181 aggagtccat tacacaaact gggggaaagg ttaccctggt ggaagaagaa gcagtctttc
3241 ttatgaagat gctgactgtg ttgttattat tggaggtgca tcaaatgaag caggaaaatg
3301 gatggatgat acctgcgaca gtaaacgagg ctacatatgc cagacacgat ccgacccttc
3361 cttgactaat cctccagcaa cgattcaaac agatggcttt gttaaatatg gcaaaagcag
3421 ctattcactc atgagacaaa aatttcaatg gcatgaagcg gagacatact gcaagcttca
3481 caattccctt atagccagca ttctggatcc ctacagtaat gcatttgcgt ggctgcagat
3541 ggaaacatct aatgaacgtg tgtggatcgc cctgaacagt aacttgactg ataatcaata
3601 cacttggact gataagtgga gggtgaggta cactaactgg gctgctgatg agcccaaatt
3661 gaaatcagca tgtgtttatc tggatcttga tggctactgg aagacagcac attgcaatga
3721 aagtttttac tttctctgta aaagatcaga tgaaatccct gctactgaac ccccacaact
3781 gcctggcaga tgcccggagt cagatcacac agcatggatt cctttccatg gtcactgtta
3841 ctatattgag tcctcatata caagaaactg gggccaagct tctctggaat gtcttcgaat
3901 gggttcctct ctggtttcca ttgaaagtgc tgcagaatcc agttttctgt catatcgggt
3961 tgagccactt aaaagtaaaa ccaatttttg gataggattg ttcagaaatg ttgaagggac
4021 gtggctgtgg ataaataaca gtccggtctc ctttgtcaac tggaacacag gagatccctc
4081 tggtgaacgg aatgattgtg tagctttaca tgcgtcttct gggttttgga gtaatattca
4141 ctgttcttcc tacaaaggat atatttgtaa aagaccaaaa attattgatg ctaaacctac
4201 tcatgaatta cttacaacaa aagctgacac aaggaagatg gacccttcta aaccgtcttc
4261 caacgtggcc ggagtagtca tcattgtgat cctcctgatt ttaacgggtg ctggccttgc
4321 cgcctatttc ttttataaga aaagacgtgt gcacctacct caagagggcg cctttgaaaa
4381 cactctgtat tttaacagtc agtcaagccc aggaactagt gatatgaaag atctcgtggg
4441 caatattgaa cagaatgaac actcggtcat ctagtacctc aatgcgattc tgagatattt
4501 gaatttcata aaattgtaac tgaaatttaa aatttttagt tcaatgtgat tgttttcttt
4561 aaaatgagta ctgaattgta ctggtctgtc cttttttcct ttgcctaatt gaagaaataa
4621 ttgcttgttt tctagcctgg caagatattt tcataaaaga gggataacaa tgctgattac
4681 taccttttaa aatattttag ataaatgcac agcaccacag caccacatct aagcattagt
4741 gatgggtagc tgatgtcagc ttcatgtgga ttttaagcac tctagaaaca atgaagcttc
4801 ttggcatatt ttaaggagct cccaaaatgt gttacctatt aaattgtaac tcagcaagta
4861 gaagaccatt tgaaaagtca ggtacaaatt tcctcaagtg gcataaaaat gtagtcagtt
4921 ttctctttta ccagttttta tttccactcc aattatttag aactttattt gtacatgtgc
4981 agaagaataa ggcagctgag aatcttgttt cccccaagag agttttacag gctgagtgtt
5041 gcaaatgtgt tctttgtcct gttatatgta tatcaggaat acaaggatgt gaaataaaac
5101 tgtaaatttg cataactgga tgtacttaga taatgtgaaa taaacattaa agacaaggtc
5161 tatttttaat aaaaaaaaaa aaaaa
//