LOCUS HUMDMP 5259 bp mRNA linear HUM 27-APR-1993
DEFINITION Human desmoplakin mRNA, 3' end.
ACCESSION J05211
VERSION J05211.1
KEYWORDS desmoplakin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5259)
AUTHORS Green,K.J., Parry,D.A., Steinert,P.M., Virata,M.L., Wagner,R.M.,
Angst,B.D. and Nilles,L.A.
TITLE Structure of the human desmoplakins. Implications for function in
the desmosomal plaque
JOURNAL J. Biol. Chem. 265 (5), 2603-2612 (1990)
PUBMED 1689290
REFERENCE 2 (sites)
AUTHORS Green,K.J., Parry,D.A., Steinert,P.M., Virata,M.L., Wagner,R.M.,
Angst,B.D. and Nilles,L.A.
TITLE Structure of the human desmoplakins. Implications for function in
the desmosomal plaque
JOURNAL J. Biol. Chem. 265 (19), 11406-11407 (1990)
PUBMED 2391353
COMMENT Original source text: Human foreskin keratinocyte, cDNA to mRNA.
[2] revises [1].
Draft entry and computer-readable sequence for [1] kindly submitted
by K.J.Green, 12-JAN-1990.
FEATURES Location/Qualifiers
source 1..5259
/db_xref="H-InvDB:HIT000191319"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS <1..5259
/note="desmoplakin"
/codon_start=1
/protein_id="AAA35766.1"
/translation="REKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKA
IKEKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTI
KEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKA
CGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEE
AKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQI
DNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQ
VTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQ
YDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQ
KQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKK
RSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHF
QKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADS
DKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQES
KNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQ
IQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKL
EDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKV
TAMQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVE
AKRKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEK
AITGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVAL
ARGLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRS
MSFQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYN
ETTKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGI
EFKEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPK
ESHRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEET
GLCLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELC
EQECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLT
QFADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRSSSFSDTL
EESSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSL
QDAVSQGVIDQDMATSVKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEF
QYLTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKD
AINRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGS
RRGSFDATGNSSYSYSYSFSSSSIGH"
BASE COUNT 1714 a 1100 c 1432 g 1013 t
ORIGIN
1 cgtgaaaaga gaagaagaaa atctgtggaa gacagatttg accaacagaa gaatgactat
61 gaccaactgc agaaagcaag gcaatgtgaa aaggagaacc ttggttggca gaaattagag
121 tctgagaaag ccatcaagga gaaggagtac gagattgaaa ggttgagggt tctactgcag
181 gaagaaggca cccggaagag agaatatgaa aatgagctgg caaaggtaag aaaccactat
241 aatgaggaga tgagtaattt aaggaacaag tatgaaacag agattaacat tacgaagacc
301 accatcaagg agatatccat gcaaaaagag gatgattcca aaaatcttag aaaccagctt
361 gatagacttt caagggaaaa tcgagatctg aaggatgaaa ttgtcaggct caatgacagc
421 atcttgcagg ccactgagca gcgaaggcga gctgaagaaa acgcccttca gcaaaaggcc
481 tgtggctctg agataatgca gaagaagcag catctggaga tagaactgaa gcaggtcatg
541 cagcagcgct ctgaggacaa tgcccggcac aagcagtccc tggaggaggc tgccaagacc
601 attcaggaca aaaataagga gatcgagaga ctcaaagctg agtttcagga ggaggccaag
661 cgccgctggg aatatgaaaa tgaactgagt aaggtaagaa acaattatga tgaggagatc
721 attagcttaa aaaatcagtt tgagaccgag atcaacatca ccaagaccac catccaccag
781 ctcaccatgc agaaggaaga ggataccagt ggctaccggg ctcagataga caatctcacc
841 cgagaaaaca ggagcttatc tgaagaaata aagaggctga agaacactct aacccagacc
901 acagagaatc tcaggagggt ggaagaagac atccaacagc aaaaggccac tggctctgag
961 gtgtctcaga ggaaacagca gctggaggtt gagctgagac aagtcactca gatgcgaaca
1021 gaggagagcg taagatataa gcaatctctt gatgatgctg ccaaaaccat ccaggataaa
1081 aacaaggaga tagaaaggtt aaaacaactg atcgacaaag aaacaaatga ccggaaatgc
1141 ctggaagatg aaaacgcgag attacaaagg gtccagtatg acctgcagaa agcaaacagt
1201 agtgcgacgg agacaataaa caaactgaag gttcaggagc aagaactgac acgcctgagg
1261 atcgactatg aaagggtttc ccaggagagg actgtgaagg accaggatat cacgcggttc
1321 cagaactctc tgaaagagct gcagctgcag aagcagaagg tggaagagga gctgaatcgg
1381 ctgaagagga ccgcgtcaga agactcctgc aagaggaaga agctggagga agagctggaa
1441 ggcatgagga ggtcgctgaa ggagcaagcc atcaaaatca ccaacctgac ccagcagctg
1501 gagcaggcat ccattgttaa gaagaggagt gaggatgacc tccggcagca gagggacgtg
1561 ctggatggcc acctgaggga aaagcagagg acccaggaag agctgaggag gctctcttct
1621 gaggtcgagg ccctgaggcg gcagttactc caggaacagg aaagtgtcaa acaagctcac
1681 ttgaggaatg agcatttcca gaaggcgata gaagataaaa gcagaagctt aaatgaaagc
1741 aaaatagaaa ttgagaggct gcagtctctc acagagaacc tgaccaagga gcacttgatg
1801 ttagaagaag aactgcggaa cctgaggctg gagtacgatg acctgaggag aggacgaagc
1861 gaagcggaca gtgataaaaa tgcaaccatc ttggaactaa ggagccagct gcagatcagc
1921 aacaaccgga ccctggaact gcaggggctg attaatgatt tacagagaga gagggaaaat
1981 ttgagacagg aaattgagaa attccaaaag caggctttag aggcatctaa taggattcag
2041 gaatcaaaga atcagtgtac tcaggtggta caggaaagag agagccttct ggtgaaaatc
2101 aaagtcctgg agcaagacaa ggcaaggctg cagaggctgg aggatgagct gaatcgtgca
2161 aaatcaactc tagaggcaga aaccagggtg aaacagcgcc tggagtgtga gaaacagcaa
2221 attcagaatg acctgaatca gtggaagact caatattccc gcaaggagga ggctattagg
2281 aagatagaat cggaaagaga aaagagtgag agagagaaga acagtcttag gagtgagatc
2341 gaaagactcc aagcagagat caagagaatt gaagagaggt gcaggcgtaa gctggaggat
2401 tctaccaggg agacacagtc acagttagaa acagaacgct cccgatatca gagggagatt
2461 gataaactca gacagcgccc atatgggtcc catcgagaga cccagactga gtgtgagtgg
2521 accgttgaca cctccaagct ggtgtttgat gggctgagga agaaggtgac agcaatgcag
2581 ctctatgagt gtcagctgat cgacaaaaca accttggaca aactattgaa ggggaagaag
2641 tcagtggaag aagttgcttc tgaaatccag ccattccttc ggggtgcagg atctatcgct
2701 ggagcatctg cttctcctaa ggaaaaatac tctttggtag aggccaagag aaagaaatta
2761 atcagcccag aatccacagt catgcttctg gaggcccagg cagctacagg tggtataatt
2821 gatccccatc ggaatgagaa gctgactgtc gacagtgcca tagctcggga cctcattgac
2881 ttcgatgacc gtcagcagat atatgcagca gaaaaagcta tcactggttt tgatgatcca
2941 ttttcaggca agacagtatc tgtttcagaa gccatcaaga aaaatttgat tgatagagaa
3001 accggaatgc gcctgctgga agcccagatt gcttcagggg gtgtagtaga ccctgtgaac
3061 agtgtctttt tgccaaaaga tgtcgccttg gcccgggggc tgattgatag agatttgtat
3121 cgatccctga atgatccccg agatagtcag aaaaactttg tggatccagt caccaaaaag
3181 aaggtcagtt acgtgcagct gaaggaacgg tgcagaatcg aaccacatac tggtctgctc
3241 ttgctttcag tacagaagag aagcatgtcc ttccaaggaa tcagacaacc tgtgaccgtc
3301 actgagctag tagattctgg tatattgaga ccgtccactg tcaatgaact ggaatctggt
3361 cagatttctt atgacgaggt tggtgagaga attaaggact tcctccaggg ttcaagctgc
3421 atagcaggca tatacaatga gaccacaaaa cagaagcttg gcatttatga ggccatgaaa
3481 attggcttag tccgacctgg tactgctctg gagttgctgg aagcccaagc agctactggc
3541 tttatagtgg atcctgttag caacttgagg ttaccagtgg aggaagccta caagagaggt
3601 ctggtgggca ttgagttcaa agagaagctc ctgtctgcag aacgagctgt cactgggtat
3661 aatgatcctg aaacaggaaa catcatctct ttgttccaag ccatgaataa ggaactcatc
3721 gaaaagggcc acggtattcg cttattagaa gcacagatcg caaccggggg gatcattgac
3781 ccaaaggaga gccatcgttt accagttgac atagcatata agaggggcta tttcaatgag
3841 gaactcagtg agattctctc agatccaagt gatgatacca aaggattttt tgaccccaac
3901 actgaagaaa atcttaccta tctgcaacta aaagaaagat gcattaagga tgaggaaaca
3961 gggctctgtc ttctgcctct gaaagaaaag aagaaacagg tgcagacatc acaaaagaat
4021 accctcagga agcgtagagt ggtcatagtt gacccagaaa ccaataaaga aatgtctgtt
4081 caggaggcct acaagaaggg cctaattgat tatgaaacct tcaaagaact gtgtgagcag
4141 gaatgtgaat gggaagaaat aaccatcacg ggatcagatg gctccaccag ggtggtcctg
4201 gtagatagaa agacaggcag tcagtatgat attcaagatg ctattgacaa gggccttgtt
4261 gacaggaagt tctttgatca gtaccgatcc ggcagcctca gcctcactca atttgctgac
4321 atgatctcct tgaaaaatgg tgtcggcacc agcagcagca tgggcagtgg tgtcagcgat
4381 gatgttttta gcagctcccg acatgaatca gtaagtaaga tttccaccat atccagcgtc
4441 aggaatttaa ccataaggag cagctctttt tcagacaccc tggaagaatc gagccccatt
4501 gcagccatct ttgacacaga aaacctggag aaaatctcca ttacagaagg tatagagcgg
4561 ggcatcgttg acagcatcac gggtcagagg cttctggagg ctcaggcctg cacaggtggc
4621 atcatccacc caaccacggg ccagaagctg tcacttcagg acgcagtctc ccagggtgtg
4681 attgaccaag acatggccac cagcgtgaag cctgctcaga aagccttcat aggcttcgag
4741 ggtgtgaagg gaaagaagaa gatgtcagca gcagaggcag tgaaagaaaa atggctcccg
4801 tatgaggctg gccagcgctt cctggagttc cagtacctca cgggaggtct tgttgacccg
4861 gaagtgcatg ggaggataag caccgaagaa gccatccgga aggggttcat agatggccgc
4921 gccgcacaga ggctgcaaga caccagcagc tatgccaaaa tcctgacctg ccccaaaacc
4981 aaattaaaaa tatcctataa ggatgccata aatcgctcca tggtagaaga tatcactggg
5041 ctgcgccttc tggaagccgc ctccgtgtcg tccaagggct tacccagccc ttacaacatg
5101 tcttcggctc cggggtcccg ctccggctcc cgctcgggat ctcgctccgg atctcgctcc
5161 gggtcccgca gtgggtcccg gagaggaagc tttgacgcca cagggaattc ttcctactct
5221 tattcctact catttagcag tagttctatt gggcactag
//