LOCUS HUMNARIA 4124 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human neutrophil adherence receptor alpha-M subunit mRNA.
ACCESSION J04145
VERSION J04145.1
KEYWORDS integrin; neutrophil adherence receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4124)
AUTHORS Hickstein,D.D.
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4124)
AUTHORS Hickstein,D.D., Hickey,M.J., Ozols,J., Baker,D.M., Back,A.L. and
Roth,G.J.
TITLE cDNA sequence for the alpha M subunit of the human neutrophil
adherence receptor indicates homology to integrin alpha subunits
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86 (1), 257-261 (1989)
PUBMED 2563162
COMMENT Original source text: Human cell line HL-60 cDNA to mRNA.
Draft entry and computer readable copy of sequence [1] kindly
submitted by D.Hickstein 27-MAR-1989.
FEATURES Location/Qualifiers
source 1..4124
/db_xref="H-InvDB:HIT000191245"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="16p11.2"
gene 1..4124
/gene="ITGAM"
CDS <1..3438
/gene="ITGAM"
/note="neutrophil adherence receptor alpha-M subunit"
/codon_start=1
/protein_id="AAA59903.1"
/db_xref="GDB:G00-120-599"
/translation="TALTLCHGFNLDTENAMTFQENARGFGQSVVQLQGSRVVVGAPQ
EIVAANQRGSLYQCDYSTGSCEPIRLQVPVEAVNMSLGLSLAATTSPPQLLACGPTVH
QTCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRR
MKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGRTH
TATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYV
IGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGS
SSSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMN
DAYLGYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFG
ASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQ
PWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAG
SKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPREV
ARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSGRPHSRA
VFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFGN
LRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVT
VRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTS
CSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPV
KYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVFLVPVRLNQ
TVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFF
GIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTET
KVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSEGGPPGAEPQ"
sig_peptide <1..24
/gene="ITGAM"
/note="neutrophil adherence receptor alpha-M subunit
signal peptide"
mat_peptide 25..3435
/gene="ITGAM"
/product="neutrophil adherence receptor alpha-M subunit
mature peptide"
BASE COUNT 906 a 1146 c 1197 g 875 t
ORIGIN Unreported.
1 acagccttga ccttatgtca tgggttcaac ttggacactg aaaacgcaat gaccttccaa
61 gagaacgcaa ggggcttcgg gcagagcgtg gtccagcttc agggatccag ggtggtggtt
121 ggagcccccc aggagatagt ggctgccaac caaaggggca gcctctacca gtgcgactac
181 agcacaggct catgcgagcc catccgcctg caggtccccg tggaggccgt gaacatgtcc
241 ctgggcctgt ccctggcagc caccaccagc ccccctcagc tgctggcctg tggtcccacc
301 gtgcaccaga cttgcagtga gaacacgtat gtgaaagggc tctgcttcct gtttggatcc
361 aacctacggc agcagcccca gaagttccca gaggccctcc gagggtgtcc tcaagaggat
421 agtgacattg ccttcttgat tgatggctct ggtagcatca tcccacatga ctttcggcgg
481 atgaaggagt ttgtctcaac tgtgatggag caattaaaaa agtccaaaac cttgttctct
541 ttgatgcagt actctgaaga attccggatt cactttacct tcaaagagtt ccagaacaac
601 cctaacccaa gatcactggt gaagccaata acgcagctgc ttgggcggac acacacggcc
661 acgggcatcc gcaaagtggt acgagagctg tttaacatca ccaacggagc ccgaaagaat
721 gcctttaaga tcctagttgt catcacggat ggagaaaagt ttggcgatcc cttgggatat
781 gaggatgtca tccctgaggc agacagagag ggagtcattc gctacgtcat tggggtggga
841 gatgccttcc gcagtgagaa atcccgccaa gagcttaata ccatcgcatc caagccgcct
901 cgtgatcacg tgttccaggt gaataacttt gaggctctga agaccattca gaaccagctt
961 cgggagaaga tctttgcgat cgagggtact cagacaggaa gtagcagctc ctttgagcat
1021 gagatgtctc aggaaggctt cagcgctgcc atcacctcta atggcccctt gctgagcact
1081 gtggggagct atgactgggc tggtggagtc tttctatata catcaaagga gaaaagcacc
1141 ttcatcaaca tgaccagagt ggattcagac atgaatgatg cttacttggg ttatgctgcc
1201 gccatcatct tacggaaccg ggtgcaaagc ctggttctgg gggcacctcg atatcagcac
1261 atcggcctgg tagcgatgtt caggcagaac actggcatgt gggagtccaa cgctaatgtc
1321 aagggcaccc agatcggcgc ctacttcggg gcctccctct gctccgtgga cgtggacagc
1381 aacggcagca ccgacctggt cctcatcggg gccccccatt actacgagca gacccgaggg
1441 ggccaggtgt ccgtgtgccc cttgcccagg gggcagaggg ctcggtggca gtgtgatgct
1501 gttctctacg gggagcaggg ccaaccctgg ggccgctttg gggcagccct aacagtgctg
1561 ggggacgtaa atggggacaa gctgacggac gtggccattg gggccccagg agaggaggac
1621 aaccggggtg ctgtttacct gtttcacgga acctcaggat ctggcatcag cccctcccat
1681 agccagcgga tagcaggctc caagctctct cccaggctcc agtattttgg tcagtcactg
1741 agtgggggcc aggacctcac aatggatgga ctggtagacc tgactgtagg agcccagggg
1801 cacgtgctgc tgctcaggtc ccagccagta ctgagagtca aggcaatcat ggagttcaat
1861 cccagggaag tggcaaggaa tgtatttgag tgtaatgatc aggtggtgaa aggcaaggaa
1921 gccggagagg tcagagtctg cctccatgtc cagaagagca cacgggatcg gctaagagaa
1981 ggacagatcc agagtgttgt gacttatgac ctggctctgg actccggccg cccacattcc
2041 cgcgccgtct tcaatgagac aaagaacagc acacgcagac agacacaggt cttggggctg
2101 acccagactt gtgagaccct gaaactacag ttgccgaatt gcatcgagga cccagtgagc
2161 cccattgtgc tgcgcctgaa cttctctctg gtgggaacgc cattgtctgc tttcgggaac
2221 ctccggccag tgctggcgga ggatgctcag agactcttca cagccttgtt tccctttgag
2281 aagaattgtg gcaatgacaa catctgccag gatgacctca gcatcacctt cagtttcatg
2341 agcctggact gcctcgtggt gggtgggccc cgggagttca acgtgacagt gactgtgaga
2401 aatgatggtg aggactccta caggacacag gtcaccttct tcttcccgct tgacctgtcc
2461 taccggaagg tgtccacgct ccagaaccag cgctcacagc gatcctggcg cctggcctgt
2521 gagtctgcct cctccaccga agtgtctggg gccttgaaga gcaccagctg cagcataaac
2581 caccccatct tcccggaaaa ctcagaggtc acctttaata tcacgtttga tgtagactct
2641 aaggcttccc ttggaaacaa actgctcctc aaggccaatg tgaccagtga gaacaacatg
2701 cccagaacca acaaaaccga attccaactg gagctgccgg tgaaatatgc tgtctacatg
2761 gtggtcacca gccatggggt ctccactaaa tatctcaact tcacggcctc agagaatacc
2821 agtcgggtca tgcagcatca atatcaggtc agcaacctgg ggcagaggag cctccccatc
2881 agcctggtgt tcttggtgcc cgtccggctg aaccagactg tcatatggga ccgcccccag
2941 gtcaccttct ccgagaacct ctcgagtacg tgccacacca aggagcgctt gccctctcac
3001 tccgactttc tggctgagct tcggaaggcc cccgtggtga actgctccat cgctgtctgc
3061 cagagaatcc agtgtgacat cccgttcttt ggcatccagg aagaattcaa tgctaccctc
3121 aaaggcaacc tctcgtttga ctggtacatc aagacctcgc ataaccacct cctgatcgtg
3181 agcacagctg agatcttgtt taacgattcc gtgttcaccc tgctgccggg acagggggcg
3241 tttgtgaggt cccagacgga gaccaaagtg gagccgttcg aggtccccaa ccccctgccg
3301 ctcatcgtgg gcagctctgt cgggggactg ctgctcctgg ccctcatcac cgccgcgctg
3361 tacaagctcg gcttcttcaa gcggcaatac aaggacatga tgagtgaagg gggtcccccg
3421 ggggccgaac cccagtagcg gctccttccc gacagagctg cctctcggtg gccagcagga
3481 ctctgcccag accacacgta gcccccaggc tgctggacac gtcggacagc gaagtatccc
3541 cgacaggacg ggcttgggct tccatttgtg tgtgtgcaag tgtgtatgtg cgtgtgtgcg
3601 agtgtgtgca agtgtctgtg tgcaagtgtg tgcacgtgtc ggtgtgcgtg catgtgcact
3661 cgcacgccca tgtgtgagtg tgtgcaagta tgtgagtgtg tccaagtgtg tgtgcgtgtg
3721 tccatgtgtg tgcaagtgtg tgcatgtgtg cgagtgtgtg catgtgtgtg ctcaggggcg
3781 tgtggctcac gtgtgtgact cagatgtctc tggcgtgtgg gtaggtgacg gccagcgtag
3841 cctctccggc agaagggaac tgcctgggct cccttgtgcg tgggtgaagc cgctgctggg
3901 ttttcctccg ggagagggga cggtcaatcc tgtgggtgaa gacagaggga aacacagcag
3961 cttctctcca ctgaaagaag tgggacttcc cgtcgcctgc agcctgcggc ctgctggagc
4021 ctgcgcagct tggatggaga ctccatgaga agccgtgggt ggaaccagga gcctcctcca
4081 caccagcgct gatgcccaat aaagatgccc actgaggaat gatg
//