LOCUS HUMEGR2A 2700 bp mRNA linear HUM 07-NOV-1994
DEFINITION Human early growth response 2 protein (EGR2) mRNA, complete cds.
ACCESSION J04076
VERSION J04076.1
KEYWORDS EGR2 gene; early growth response protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2700)
AUTHORS Joseph,L.J., Le Beau,M.M., Jamieson,G.A. Jr., Acharya,S.,
Shows,T.B., Rowley,J.D. and Sukhatme,V.P.
TITLE Molecular cloning, sequencing, and mapping of EGR2, a human early
growth response gene encoding a protein with 'zinc-binding finger'
structure
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85 (19), 7164-7168 (1988)
PUBMED 3140236
COMMENT Original source text: Human foreskin fibroblast cell line 303
(lambdaZap 303), cDNA to mRNA, clones Zap [2,8,32].
Draft entry and computer-readable sequence for [1] kindly provided
by V.P.Sukhatme, 31-AUG-1988.
FEATURES Location/Qualifiers
source 1..2700
/db_xref="H-InvDB:HIT000191231"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="10q21.1"
gene 1..2700
/gene="EGR2"
mRNA <1..2700
/gene="EGR2"
/product="EGR2 mRNA"
CDS 204..1424
/gene="EGR2"
/note="early growth response 2 protein"
/codon_start=1
/protein_id="AAA52372.1"
/db_xref="GDB:G00-120-611"
/translation="MNGVAGDGMINIDMTGEKRSLDLPYPSSFAPVSAPRNQTFTYMG
KFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASPNPLATGPLGVC
TMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLAYPPPPSYPS
PKPATDPGLFPMIPDYPGFFPSQCQRDLHGTAGPDRKPFPCPLDTLRVPPPLTPLSTI
RNFTLGGPSAGMTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRPILRPRKY
PNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDH
LTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSSAPSASVPAPSTAS
CSGGVQAWGYPVQQ"
BASE COUNT 638 a 763 c 635 g 664 t
ORIGIN 357 bp upstream of RsaI site; Chromosome 10q21-q22.
1 tctgacactc caggtagcga gggagttggg tctccaggtt gtgcgaggag caaatgatga
61 ccgccaaggc cgtagacaaa atcccagtaa ctctcagtgg ttttgtgcac cagctgtctg
121 acaacatcta cccggtggag gacctcgccg ccacgtcggt gaccatcttt cccaatgccg
181 aactgggagg cccctttgac cagatgaacg gagtggccgg agatggcatg atcaacattg
241 acatgactgg agagaagagg tcgttggatc tcccatatcc cagcagcttt gctcccgtct
301 ctgcacctag aaaccagacc ttcacttaca tgggcaagtt ctccattgac ccacagtacc
361 ctggtgccag ctgctaccca gaaggcataa tcaatattgt gagtgcaggc atcttgcaag
421 gggtcacttc cccagcttca accacagcct catccagcgt cacctctgcc tcccccaacc
481 cactggccac aggacccctg ggtgtgtgca ccatgtccca gacccagcct gacctggacc
541 acctgtactc tccgccaccg cctcctcctc cttattctgg ctgtgcagga gacctctacc
601 aggacccttc tgcgttcctg tcagcagcca ccacctccac ctcttcctct ctggcctacc
661 caccacctcc ttcctatcca tcccccaagc cagccacgga cccaggtctc ttcccaatga
721 tcccagacta tcctggattc tttccatctc agtgccagag agacctacat ggtacagctg
781 gcccagaccg taagcccttt ccctgcccac tggacaccct gcgggtgccc cctccactca
841 ctccactctc tacaatccgt aactttaccc tggggggccc cagtgctggg atgaccggac
901 caggggccag tggaggcagc gagggacccc ggctgcctgg tagcagctca gcagcagcag
961 cagccgccgc cgccgccgcc tataacccac accacctgcc actgcggccc attctgaggc
1021 ctcgcaagta ccccaacaga cccagcaaga cgccggtgca cgagaggccc tacccgtgcc
1081 cagcagaagg ctgcgaccgg cggttctccc gctctgacga gctgacacgg cacatccgaa
1141 tccacactgg gcataagccc ttccagtgtc ggatctgcat gcgcaacttc agccgcagtg
1201 accacctcac cacccatatc cgcacccaca ccggtgagaa gcccttcgcc tgtgactact
1261 gtggccgaaa gtttgcccgg agtgatgaga ggaagcgcca caccaagatc cacctgagac
1321 agaaagagcg gaaaagcagt gccccctctg catcggtgcc agccccctct acagcctcct
1381 gctctggggg cgtgcaggcc tgggggtacc ctgtgcagca gtaacagcag cagtcttggc
1441 ggagggccgc tcgccccttg ctcctctcgg acccggacac cttgagatga gactcaggct
1501 gatacaccag ctcccaaagg tcccggaggc cctttgtcca ctggagctgc acaacaaaca
1561 ctaccaccct ttcctgtccc tctctccctt tgttgggcaa agggctttgg tggagctagc
1621 actgccccct ttccacctag aagcaggttc ttcctaaaac ttagcccatt ctagtctctc
1681 ttaggtgagt tgactatcaa cccaaggcaa aggggaggct cagaaggagg tggtgtgggg
1741 atcccctggc caagagggct gaggtctgac cctgctttaa agggttgttt gactaggttt
1801 tgctacccca cttcccctta ttttgaccca tcacaggttt ttgaccctgg atgtcagagt
1861 tgatctaaga cgttttctac aataggttgg gagatgctga tcccttcaag tggggacagc
1921 aaaaagacaa gcaaaactga tgtgcacttt atggcttggg actgatttgg gggacattgt
1981 acagtgagtg aagtatagcc tttatgccac actctgtggc cctaaaatgg tgaatcagag
2041 catatctagt tgtctcaacc cttgaagcaa tatgtattat atactcagag aacagaagtg
2101 caatgtgatg ggaggaacgt agcaatatct gctccttttc gagttgtttg agaaatgtag
2161 gctatttttt cagtgtatat ccactcagat tttgtgtatt tttgatgtac ccacactgtt
2221 ctctaaattc tgaatctttg ggaaaaaatg taaagcattt atgatctcag aggttaactt
2281 atttaagggg gatgtacata ttctctgaaa ctaggatgca tgcaattgtg ttggaagtgt
2341 ccttggtcgc cttgtgtgat gtagacaaat gttacaaggc tgcatgtaaa tgggttgcct
2401 tattatggag aaaaaaatca ctccctgagt ttagtatggc tgtatattta tgcctattaa
2461 tatttggaat tttttttaga aagtatattt ttgtatgctt tgttttgtga cttaaaagtg
2521 ttacctttgt agtcaaattt cagataagaa tgtacataat gttaccggag ctgatttgtt
2581 tggtcattag ctcttaatag ttgtgaaaaa ataaatctat tctaacgcaa aaccactaac
2641 tgaagttcag atataatgga tggtttgtga ctatagtgta aataaatact tttcaacaat
//