LOCUS HUMPMPCA 4398 bp mRNA linear HUM 19-AUG-1995
DEFINITION Human plasma membrane Ca2+ pumping ATPase mRNA, complete cds.
ACCESSION J04027
VERSION J04027.1
KEYWORDS plasma membrane Ca pumping ATPase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4398)
AUTHORS Verma,A.K., Filoteo,A.G., Stanford,D.R., Wieben,E.D.,
Penniston,J.T., Strehler,E.E., Fischer,R., Heim,R., Vogel,G.,
Mathews,S., Strehler-Page,M.-A., James,P., Vorherr,T., Krebs,J. and
Carafoli,E.
TITLE Complete primary structure of a human plasma membrane Ca2+ pump
JOURNAL J. Biol. Chem. 263 (28), 14152-14159 (1988)
PUBMED 2844759
COMMENT On Aug 22, 1995 this sequence version replaced gi:190132.
Original source text: Homo sapiens (clone: t[6,8.1,19c].) teratoma
cDNA to mRNA.
Draft entry and computer-readable sequence for [J. Biol. Chem.
(1988) In press] kindly provided
by J.Penniston, 22-JUL-1988.
FEATURES Location/Qualifiers
source 1..4398
/db_xref="H-InvDB:HIT000191223"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="12q21-q23"
/clone="t[6,8.1,19c]."
/cell_line="NTera2D1"
/tissue_type="teratoma"
gene 1..4398
/gene="ATP2B1"
CDS 182..3844
/gene="ATP2B1"
/codon_start=1
/product="plasma membrane Ca2+ pumping ATPase"
/protein_id="AAA74511.1"
/db_xref="GDB:G00-127-283"
/translation="MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTD
ALRKIQESYGDVYGICTKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLV
WEALQDVTLIILEIAAIVSLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAIL
LSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQV
KYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSGTHVREGSGRMVVT
AVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQ
PLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYF
VIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKM
MKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIPP
NILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNE
IPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVF
RPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGI
EDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFN
RRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDG
TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL
QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR
KPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHY
TIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKP
FSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAE
DVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSSIHNFMT
HPEFRIEDSEPHIPLIDDTDAEDDAPTKRNSSPPPSPNKNNNAVDSGIHLTIEMNKSA
TSSSPGSPLHSLETSL"
polyA_site 4398
/gene="ATP2B1"
/note="G00-127-283"
BASE COUNT 1412 a 744 c 991 g 1251 t
ORIGIN 2 bp upstream of HaeIII site.
1 ggccaaaggt caagatactt ctctgggaaa tgttgctgct gatgctgctt tacaaagtca
61 tacaatgagt gtttggttta agaaagattt tcatacttaa aagattttca tcttggaaat
121 acatcaagtg aaaattaaat tcttttggga aacattttcc ttctgatata ttatacttgt
181 aatgggcgac atggcaaaca actcagttgc ttacagtggt gtgaaaaact ctttgaagga
241 agctaatcat gatggagact ttggaattac gctcgcagag ctgcgggctc tcatggagct
301 caggtccaca gatgcattac gaaaaataca ggaaagctat ggagatgtct atggaatttg
361 caccaaattg aaaacatctc ccaatgaagg tttaagtgga aaccctgcag atttagaaag
421 aagagaagca gtgtttggaa agaattttat acctcctaaa aagccaaaaa cctttcttca
481 attagtatgg gaagcattac aagatgtcac tttaattata ttagaaattg cagccatagt
541 atcattgggc ctttcttttt atcagcctcc agaaggggat aatgcacttt gtggagaagt
601 ttctgttggg gaggaagaag gtgaaggtga aactgggtgg attgaaggag ctgcaatcct
661 cttgtctgta gtgtgtgtgg tgttagtaac agctttcaat gactggagta aggagaaaca
721 gtttagaggt ttgcagagcc gaattgaaca agaacagaag ttcactgtca tcaggggtgg
781 tcaggtcatt cagatacctg tagctgacat tactgttgga gatattgctc aagtgaaata
841 tggtgatctt cttccagctg acggcatact tattcaaggc aacgatctta aaattgatga
901 aagctcattg actggtgaat cagatcatgt taaaaagtct ttagataagg atcccttact
961 tctatcaggt actcatgtaa gggaaggctc tggaagaatg gtagttacag ctgtaggtgt
1021 aaattctcaa actggaatta tctttacctt acttggagct ggaggtgaag aggaagagaa
1081 gaaagatgag aagaaaaagg aaaagaaaaa taagaaacaa gatggagcta ttgagaatcg
1141 caacaaagca aaagcccagg atggtgcagc catggaaatg cagccattga agagtgaaga
1201 aggtggagat ggtgatgaaa aagataaaaa gaaagcaaat ttgccaaaaa aggaaaaatc
1261 tgttttacaa gggaaactta caaaactggc tgttcagatt ggcaaagcag gtctgttgat
1321 gtctgccatc acagttatca ttctagtatt atattttgtc attgacacct tctgggttca
1381 gaaaagacca tggcttgctg agtgcacacc aatttatata caatactttg tgaagttctt
1441 cattattgga gttacagttt tagtggtcgc agtgccagaa ggtcttccac ttgcagtcac
1501 gatctcactg gcttattcag tcaaaaaaat gatgaaagat aataacttag taaggcatct
1561 ggatgcttgt gaaaccatgg gaaatgctac agctatttgt tcagataaaa caggaacttt
1621 gacaatgaac agaatgacag tcgttcaagc ttacataaat gaaaaacatt ataaaaaggt
1681 tcctgaacca gaagctattc caccaaatat tttgtcctat cttgtaacag gaatttctgt
1741 gaattgtgct tatacatcaa aaatattgcc accagagaaa gagggtggat tacctcgtca
1801 cgttggtaat aaaactgaat gtgccttgtt gggacttctt ttggatttaa aacgggatta
1861 tcaggatgtt agaaatgaaa taccagaaga agcactgtac aaagtctaca ccttcaattc
1921 tgttaggaag tccatgagta ctgtcctgaa aaattcagat ggaagttatc gaatattcag
1981 caagggtgca tctgagataa ttctgaaaaa gtgtttcaaa atcttgagtg ctaatggtga
2041 ggcaaaagta ttcagaccaa gggaccgtga tgatattgta aaaactgtga ttgaaccgat
2101 ggcatcagaa ggcttgagaa ccatatgtct tgcattcaga gattttccag caggagaacc
2161 agaaccagag tgggataatg aaaatgatat tgtcaccggc cttacatgca ttgctgttgt
2221 ggggattgaa gatcctgtga gacctgaggt gccagatgca attaaaaagt gtcagagggc
2281 tggaattact gtgcggatgg tcactggtga taatattaat actgctcggg ccattgctac
2341 caaatgtggt attttacatc ctggggaaga ttttctgtgc ctagaaggta aagattttaa
2401 cagaagaata cgaaatgaaa aaggagagat tgagcaagag aggatagaca agatttggcc
2461 aaaacttcga gtacttgcaa gatcatctcc tactgataag catacactgg ttaaaggtat
2521 aattgacagc actgtctcag accaacgcca ggttgtagct gtaactggtg atggtacaaa
2581 tgatggccca gcactaaaga aagcagatgt tggatttgca atgggtattg ctggaactga
2641 tgtagctaaa gaagcatccg atattattct cacagatgac aactttacaa gcattgttaa
2701 agcagttatg tggggacgaa atgtctatga cagcatctca aaattccttc agttccaact
2761 tactgttaat gtagtagcag tgattgttgc ttttacgggc gcctgcatta ctcaagactc
2821 accgcttaag gctgtgcaga tgctgtgggt aaacctcata atggatacac tcgcttccct
2881 ggctctggca acggaaccac ccactgagtc tctcttgctt cggaaacctt atggtagaaa
2941 taagcctctc atctcacgta caatgatgaa gaatattttg ggtcatgcat tctatcaact
3001 tgtagtagtc tttacactct tatttgctgg agaaaagttt tttgacattg atagtggaag
3061 aaatgctcct ttgcatgctc ctccttcaga acattatact attgttttta atacctttgt
3121 gctgatgcaa cttttcaacg aaataaatgc ccggaaaatt catggtgaaa gaaatgtatt
3181 cgaaggaatc tttaacaatg ccatcttctg cacaattgtt ttaggcactt ttgtggtaca
3241 gataataatt gtgcagtttg gtggaaaacc tttcagttgt tcagaacttt caatagaaca
3301 gtggctatgg tcaatattcc taggaatggg aacattactc tggggccagc ttatttcaac
3361 aattccaact agccgtttaa aattcctcaa agaagctggt catggaacac aaaaggaaga
3421 aatacctgag gaggaattag cagaggatgt tgaagagatt gatcacgctg aaagggagtt
3481 gcggcgtggc caaatcttgt ggtttagagg tctgaacaga atccaaacac agattcgagt
3541 ggtgaatgca tttcgtagtt ctttatatga agggttagaa aaaccggaat caagaagttc
3601 gattcacaac tttatgacac atcctgagtt taggatagaa gattcagagc ctcatatccc
3661 ccttattgat gacactgatg ccgaagatga tgctcctaca aaacgtaact ccagtcctcc
3721 accctctccc aacaaaaata acaatgctgt tgacagtgga attcacctta caatagaaat
3781 gaacaagtct gctacctctt catccccagg aagcccacta catagtttgg aaacatcact
3841 ctgattgtaa gctgaatgtt aacacactag ctgcattgta aagaaacaaa ttgaaactgg
3901 gtcttttcac atattgtgat ggacaagcta gtattcttgt ctttggactt caacagaaga
3961 cacacttgta cgaatgtaga tttatttttt taaaaaaaaa aaagcaaagc tttctgccag
4021 actgagggtg ctttttgggg ggtgggagaa atgaactgac agataaacag taactcagcg
4081 taagtgacct gtggatcatc agtagtaccc aagcatggtc ctgaacagtg tattagcaga
4141 gctttagttt atctcagtcc tggatgggag agagagggag gagtaaaact gggcaagaca
4201 aagagccctg gatcgttgaa ttgatagttt aatttctgct gttggctgtt aataatttgg
4261 attatttatg tttataaatg atacagatct gtttacaagg tttgtagata ctttttttgt
4321 tcctgttcat agatgggaag cttccttata actgatgcag agaaaaatta gtccttcaaa
4381 tactgctgta ttttcagg
//