LOCUS HUMELI 2677 bp mRNA linear HUM 27-APR-1993
DEFINITION Human erythroid isoform protein 4.1 mRNA, complete cds.
ACCESSION J03796
VERSION J03796.1
KEYWORDS erythroid protein 4.1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2677)
AUTHORS Tang,T.K., Leto,T.L., Correas,I., Alonso,M.A., Marchesi,V.T. and
Benz,E.J. Jr.
TITLE Selective expression of an erythroid-specific isoform of protein
4.1
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85 (11), 3713-3717 (1988)
PUBMED 3375238
COMMENT Original source text: Human T-cell leukemia line MOLT-4, cDNA to
mRNA, clones pTM-[1,2].
Draft entry and printed copy of sequence for [1] kindly provided by
T.K.Tang, 26-APR-1988.
FEATURES Location/Qualifiers
source 1..2677
/db_xref="H-InvDB:HIT000191200"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 47..2374
/note="erythroid protein 4.1 isoform A"
/codon_start=1
/protein_id="AAA35793.1"
/translation="MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAE
GDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEV
ESDKEKGEGGQKEIEFGTSLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQPAQE
ELREDPDFEIKEGEGLEECSKIEVKEESPQSKAETELKASQKPIRKHRNMHCKVSLLD
DTVYECVVETWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQ
DIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVME
LHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKL
RINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHT
FFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSL
DGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDE
PPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSP
FRTLNINGQIPTGEGPPLVKTQTVTISDNANAVKSEIPTKDVPIVHTETKTITYEAAQ
TDDNSGDLDPGVLLTAQTITSETPSSTTTTKITKTVKGGISETRIEKRIVITGDADID
HDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE"
CDS 674..2374
/note="erythroid protein 4.1 isoform B"
/codon_start=1
/protein_id="AAA35794.1"
/translation="MHCKVSLLDDTVYECVVETWLDSAKEIKKQVRGVPWNFTFNVKF
YPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHG
VDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAK
DLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYEST
IGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQA
SALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDAS
AKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKK
NFMESVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGPPLVKTQTVTISDNANAVKS
EIPTKDVPIVHTETKTITYEAAQTDDNSGDLDPGVLLTAQTITSETPSSTTTTKITKT
VKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEIADE
"
BASE COUNT 873 a 604 c 603 g 597 t
ORIGIN 828 bp upstream of HincII site; chromosome 1p32-1pter.
1 agaacgcggt cggcccggtc cccgccgcac ccagcccagc aacatcatga caacagagaa
61 gagtttagtg actgaggccg aaaattcaca gcaccaacag aaggaagagg gtgaggaagc
121 cataaactca ggccaacaag aacctcagca ggaggaatct tgtcaaacag cagctgaagg
181 agataattgg tgtgaacaga agctgaaagc ttctaatgga gacactccta cacatgaaga
241 cttgaccaag aacaaggagc ggacatcaga aagcagagga ctttcacgac tattctcctc
301 gtttctcaaa aggcccaaat ctcaggtgtc cgaggaagaa ggcaaagaag tagagtcaga
361 taaagaaaaa ggtgaaggag gtcagaaaga gatagaattt ggaaccagtc ttgatgaaga
421 gatcatttta aaggccccaa ttgcagctcc tgaaccggaa ctcaaaacag acccatcttt
481 ggatcttcat tcattaagca gtgcagaaac acagcctgct caggaagaac tcagagaaga
541 tccagatttt gaaattaagg aaggagaagg acttgaagag tgctccaaaa tagaagtaaa
601 agaagaaagc cctcaatcaa aagcagaaac agaattaaaa gcttcccaaa aaccaatcag
661 aaaacacagg aacatgcact gcaaggtttc tttgttggat gacacagttt atgaatgtgt
721 tgtggagaca tggctggatt ccgccaaaga aataaaaaag caggttcgtg gtgtcccttg
781 gaattttaca tttaatgtaa agttttatcc acctgaccca gcacagttaa cagaagacat
841 aacaagatat tatttatgtc ttcagcttcg gcaggacata gttgcaggac gtctgccctg
901 ttcctttgca accttagcat tattaggttc ttacaccatc cagtctgaac tgggagacta
961 cgacccagaa ctccatggcg tggattatgt tagtgatttt aaactggccc cgaatcagac
1021 caaggaactt gaagagaagg tcatggaact gcataagtca tacaggtcca tgactccagc
1081 tcaggctgac ttggagtttc ttgagaatgc caaaaagttg tctatgtatg gagttgatct
1141 tcataaagca aaggacttgg aaggagtaga tatcatccta ggtgtctgct ctagtggcct
1201 tctggtttac aaagataagc tgagaattaa ccgcttccct tggcccaaag tgctgaagat
1261 ttcttataaa cgtagtagct ttttcatcaa gattcggcct ggagagcaag agcagtatga
1321 aagtaccatc ggattcaaac ttcccagtta ccgagcagct aagaaattat ggaaagtctg
1381 tgtagaacat cacacgtttt tcagattgac atctacagac accattccca aaagcaaatt
1441 tcttgcgcta ggatccaaat ttcgatacag tggccggact caagctcaga ccaggcaagc
1501 tagtgctcta attgacaggc ctgccccaca cttcgagcgt acagcaagta aacgggcgtc
1561 ccggagcctc gatggagcag cagctgtcga ttcggcagac cgaagtcctc ggcccacttc
1621 tgcacctgcc attactcagg gtcaggttgc agaaggtggc gtcctagatg cctctgctaa
1681 aaaaacagtg gtccctaaag cacagaagga aacagtgaag gctgaagtga aaaaggaaga
1741 cgagccacct gagcaagctg agccagagcc cacagaagca tggaaggatt tagacaagag
1801 tcaagaggag atcaaaaaac atcatgccag catcagtgag ctgaaaaaga acttcatgga
1861 gtctgtacca gaaccacggc ctagtgaatg ggataaacgc ttatccactc actcaccctt
1921 ccgaactctt aacatcaatg ggcaaatccc cacaggagaa ggacctcccc tggtgaagac
1981 acaaactgtc accatctcag ataatgccaa tgctgtgaaa agtgaaatcc caaccaaaga
2041 cgtccctatt gtccacactg agaccaagac catcacttat gaggctgccc agactgacga
2101 caacagtgga gacttggacc caggagtctt gctgacagct caaactatca catctgagac
2161 cccaagcagc accaccacaa ctaaaattac caagactgta aaaggtggga tttcagagac
2221 acgtattgaa aagagaattg tgatcacagg agatgctgat attgaccatg atcaggtcct
2281 tgtacaagcc atcaaggagg caaaggagca gcacccagac atgtcagtga ccaaggtggt
2341 cgtccaccag gagaccgaga ttgctgatga gtgagctcag gaactaacct accccaactc
2401 tgcccttctc ccatccaaga gaaaccagca aaatgataaa gaagctaacc tgccatagtc
2461 agacttcaga ctttcaagat tattctaaat caccagaaaa ttaatttcag tttctattgg
2521 gagtttatac caagagattc ttctagatct cattgatcct tttgaagagc tttttctata
2581 ttaggatatc agaattgttc aacttttcac tctatagact gttttaagag ttttggggtt
2641 ttttttaatt gggtggtttg taaccccttc agcctag
//