LOCUS HUMPAI2A 1854 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human plasminogen activator inhibitor mRNA, complete cds.
ACCESSION J03603
VERSION J03603.1
KEYWORDS plasminogen activator inhibitor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1854)
AUTHORS Antalis,T.M., Clark,M.A., Barnes,T., Lehrbach,P.R., Devine,P.L.,
Schevzov,G., Goss,N.H., Stephens,R.W. and Tolstoshev,P.
TITLE Cloning and expression of a cDNA coding for a human
monocyte-derived plasminogen activator inhibitor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85 (4), 985-989 (1988)
PUBMED 3257578
COMMENT Original source text: Human monocyte cell line U937, cDNA to mRNA,
clone BTA1445.
Draft entry and printed copy of sequence for [1] kindly provided by
T.M.Antalis, 01/19/88. Polyadenylation signals are located at
positions 1432-1437, 1637-1642, 1678-1683 and 1741-1746.
FEATURES Location/Qualifiers
source 1..1854
/db_xref="H-InvDB:HIT000191186"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="1q23"
gene 1..1854
/gene="FCER1A"
CDS 49..1296
/gene="FCER1A"
/note="plasminogen activator inhibitor precursor"
/codon_start=1
/protein_id="AAA60004.1"
/db_xref="GDB:G00-119-902"
/translation="MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYM
GSRGSTEDQMAKVLQFNEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADK
IHSSFRSLSSAINASTGNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLE
CAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNG
LYPFRVNSAQRTPVQMMYLREKLNIGYIEDLKAQILELPYAGDVSMFLLLPDEIADVS
TGLELLESEITYDKLNKWTSKDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFN
KGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADH
PFLFLIMHKITNCILFFGRFSSP"
mat_peptide 52..1293
/gene="FCER1A"
/product="plasminogen activator inhibitor"
BASE COUNT 574 a 378 c 374 g 528 t
ORIGIN 13 bp upstream of DdeI site.
1 gtcagacagc aactcagaga ataaccagag aacaaccaga ttgaaacaat ggaggatctt
61 tgtgtggcaa acacactctt tgccctcaat ttattcaagc atctggcaaa agcaagcccc
121 acccagaacc tcttcctctc cccatggagc atctcgtcca ccatggccat ggtctacatg
181 ggctccaggg gcagcaccga agaccagatg gccaaggtgc ttcagtttaa tgaagtggga
241 gccaatgcag ttacccccat gactccagag aactttacca gctgtgggtt catgcagcag
301 atccagaagg gtagttatcc tgatgcgatt ttgcaggcac aagctgcaga taaaatccat
361 tcatccttcc gctctctcag ctctgcaatc aatgcatcca cagggaatta tttactggaa
421 agtgtcaata agctgtttgg tgagaagtct gcgagcttcc gggaagaata tattcgactc
481 tgtcagaaat attactcctc agaaccccag gcagtagact tcctagaatg tgcagaagaa
541 gctagaaaaa agattaattc ctgggtcaag actcaaacca aaggcaaaat cccaaacttg
601 ttacctgaag gttctgtaga tggggatacc aggatggtcc tggtgaatgc tgtctacttc
661 aaaggaaagt ggaaaactcc atttgagaag aaactaaatg ggctttatcc tttccgtgta
721 aactcggctc agcgcacacc tgtacagatg atgtacttgc gtgaaaagct aaacattgga
781 tacatagaag acctaaaggc tcagattcta gaactcccat atgctggaga tgttagcatg
841 ttcttgttgc ttccagatga aattgccgat gtgtccactg gcttggagct gctggaaagt
901 gaaataacct atgacaaact caacaagtgg accagcaaag acaaaatggc tgaagatgaa
961 gttgaggtat acatacccca gttcaaatta gaagagcatt atgaactcag atccattctg
1021 agaagcatgg gcatggagga cgccttcaac aagggacggg ccaatttctc agggatgtcg
1081 gagaggaatg acctgtttct ttctgaagtg ttccaccaag ccatggtgga tgtgaatgag
1141 gagggcactg aagcagccgc tggcacagga ggtgttatga cagggagaac tggacatgga
1201 ggcccacagt ttgtggcaga tcatcctttt ctttttctta ttatgcataa gataaccaac
1261 tgcattttat ttttcggcag attttcctca ccctaaaact aagcgtgctg cttctgcaaa
1321 agatttttgt agatgagctg tgtgcctcag aattgctatt tcaaattgcc aaaaatttag
1381 agatgttttc tacatatttc tgctcttctg aacaacttct gctacccact aaataaaaac
1441 acagaaataa ttagacaatt gtctattata acatgacaac cctattaatc atttggtctt
1501 ctaaaatggg atcatgccca tttagatttt ccttactatc agtttatttt tataacatta
1561 acttttactt tgttatttat tattttatat aatggtgagt ttttaaatta ttgctcactg
1621 cctatttaat gtagctaata aagttataga agcagatgat ctgttaattt cctatctaat
1681 aaatgccttt aattgttctc ataatgaaga ataagtaggt atccctccat gcccttctgt
1741 aataaatatc tggaaaaaac attaaacaat aggcaaatat atgttatgtg catttctaga
1801 aatacataac acatatatat gtctgtatct tatattcaat tgcaagtata taat
//