LOCUS HUMC7A 3890 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human complement protein component C7 mRNA, complete cds.
ACCESSION J03507
VERSION J03507.1
KEYWORDS complement component C2; complement protein C7.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3890)
AUTHORS DiScipio,R.G., Chakravarti,D.N., Muller-Eberhard,H.J. and Fey,G.H.
TITLE The structure of human complement component C7 and the C5b-7
complex
JOURNAL J. Biol. Chem. 263 (1), 549-560 (1988)
PUBMED 3335508
COMMENT Original source text: Human liver, cDNA to mRNA, clone lambda-GT11.
Draft entry and computer-readable copy of sequence [1] kindly
provided by R.G.DiScipio 06-JAN-1988.
FEATURES Location/Qualifiers
source 1..3890
/db_xref="H-InvDB:HIT000191163"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="5p14-p12"
gene 1..3890
/gene="C7"
CDS 1..2532
/gene="C7"
/note="complement protein C7 precursor"
/codon_start=1
/protein_id="AAA51861.1"
/db_xref="GDB:G00-119-046"
/translation="MKVISLFILVGFIGEFQSFSSASSPVNCQWDFYAPWSECNGCTK
TQTRRRSVAVYGQYGGQPCVGNAFETQSCEPTRGCPTEEGCGERFRCFSGQCISKSLV
CNGDSDCDEDSADEDRCEDSERRPSCDIDKPPPNIELTGNGYNELTGQFRNRVINTKS
FGGQCRKVFSGDGKDFYRLSGNVLSYTFQVKINNDFNYEFYNSTWSYVKHTSTEHTSS
SRKRSFFRSSSSSSRSYTSHTNEIHKGKSYQLLVVENTVEVAQFINNNPEFLQLAEPF
WKELSHLPSLYDYSAYRRLIDQYGTHYLQSGSLGGEYRVLFYVDSEKLKQNDFNSVEE
KKCKSSGWHFVVKFSSHGCKELENALKAASGTQNNVLRGEPFIRGGGAGFISGLSYLE
LDNPAGNKRRYSAWAESVTNLPQVIKQKLTPLYELVKEVPCASVKKLYLKWALEEYLD
EFDPCHCRPCQNGGLATVEGTHCLCHCKPYTFGAACEQGVLVGNQAGGVDGGWSCWSS
WSPCVQGKKTRSRECNNPPPSGGGRSCVGETTESTQCEDEELEHLRLLEPHCFPLSLV
PTEFCPSPPALKDGFVQDEGPMFPVGKNVVYTCNEGYSLIGNPVARCGEDLRWLVGEM
HCQKIACVLPVLMDGIQSHPQKPFYTVGEKVTVSCSGGMSLEGPSAFLCGSSLKWSPE
MKNARCVQKENPLTQAVPKCQRWEKLQNSRCVCKMPYECGPSLDVCAQDERSKRILPL
TVCKMHVLHCQGRNYTLTGRDSCTLPASAEKACGACPLWGKCDAESSKCVCREASECE
EEGFSICVEVNGKEQTMSECEAGALRCRGQSISVTSIRPCAAETQ"
sig_peptide 1..66
/gene="C7"
/note="complement protein C7 signal peptide"
mat_peptide 67..2529
/gene="C7"
/product="complement protein C7"
BASE COUNT 1073 a 799 c 931 g 1087 t
ORIGIN 1707 bp upstream of EcoRI site; Linkage group 2.
1 atgaaggtga taagcttatt cattttggtg ggatttatag gagagttcca aagtttttca
61 agtgcctcct ctccagtcaa ctgccagtgg gacttctatg ccccttggtc agaatgcaat
121 ggctgtacca agactcagac tcgcaggcgg tcagttgctg tgtatgggca gtatggaggc
181 cagccttgtg ttggaaatgc ttttgaaaca cagtcctgtg aacctacaag aggatgtcca
241 acagaggagg gatgtggaga gcgtttcagg tgcttttcag gtcagtgcat cagcaaatca
301 ttggtttgca atggggattc tgactgtgat gaagacagtg ctgatgaaga cagatgtgag
361 gactcagaaa ggagaccttc ctgtgatatc gataaacctc ctcctaacat agaacttact
421 ggaaatggtt acaatgaact cactggccag tttaggaaca gagtcatcaa taccaaaagt
481 tttggtggtc aatgtagaaa ggtgtttagt ggggatggaa aagatttcta caggctgagt
541 ggaaatgtcc tgtcctatac attccaggtg aaaataaata atgattttaa ttatgaattt
601 tacaatagta cttggtctta tgtaaaacat acgtcgacag aacacacatc atctagtcgg
661 aagcgctcct tttttagatc ttcatcatct tcttcacgca gttatacttc acataccaat
721 gaaatccata aaggaaagag ttaccaactg ctggttgttg agaacactgt tgaagtggct
781 cagttcatta ataacaatcc agaattttta caacttgctg agccattctg gaaggagctt
841 tcccacctcc cctctctgta tgactacagt gcctaccgaa gattaatcga ccagtacggg
901 acacattatc tgcaatctgg gtcgttagga ggagaataca gagttctatt ttatgtggac
961 tcagaaaaat taaaacaaaa tgattttaat tcagtcgaag aaaagaaatg taaatcctca
1021 ggttggcatt ttgtcgttaa attttcaagt catggatgca aggaactgga aaacgcttta
1081 aaagctgctt caggaaccca gaacaatgta ttgcgaggag aaccgttcat cagaggggga
1141 ggtgcaggct tcatatctgg ccttagttac ctagagctgg acaatcctgc tggaaacaaa
1201 aggcgatatt ctgcctgggc agaatctgtg actaatcttc ctcaagtcat aaaacaaaag
1261 ctgacacctt tatatgagct ggtaaaggaa gtaccttgtg cctctgtgaa aaaactatac
1321 ctgaaatggg ctcttgaaga gtatctggat gaatttgacc cctgtcattg ccggccttgt
1381 caaaatggtg gtttggctac tgttgagggg acccattgtc tgtgccattg caaaccgtac
1441 acatttggtg cggcgtgtga gcaaggagtc ctcgtaggga atcaagcagg aggggttgat
1501 ggaggttgga gttgctggtc ctcttggagc ccctgtgtcc aagggaagaa aacaagaagc
1561 cgtgaatgca ataacccacc tcccagtggg ggtgggagat cctgcgttgg agaaacgaca
1621 gaaagcacac aatgcgaaga tgaggagctg gagcacttga ggttgcttga accacattgc
1681 tttcctttgt ctttggttcc aacagaattc tgtccatcac ctcctgcctt gaaagatgga
1741 tttgttcaag atgaaggtcc aatgtttcct gtggggaaaa atgtagtgta cacttgcaat
1801 gaaggatact ctcttattgg aaacccagtg gccagatgtg gagaagattt acggtggctt
1861 gttggggaaa tgcattgtca gaaaattgcc tgtgttctac ctgtactgat ggatggcata
1921 cagagtcacc cccaaaaacc tttctacaca gttggtgaga aggtgactgt ttcctgttca
1981 ggtggcatgt ccttagaagg tccttcagca tttctctgtg gctccagcct taagtggagt
2041 cctgagatga agaatgcccg ctgtgtacaa aaagaaaatc cgttaacaca ggcagtgcct
2101 aaatgtcagc gctgggagaa actgcagaat tcaagatgtg tttgtaaaat gccctacgaa
2161 tgtggacctt ccttggatgt atgtgctcaa gatgagagaa gcaaaaggat actgcctctg
2221 acagtttgca agatgcatgt tctccactgt cagggtagaa attacaccct tactggtagg
2281 gacagctgta ctctgcctgc ctcagctgag aaagcttgtg gtgcctgccc actgtgggga
2341 aaatgtgatg ctgagagcag caaatgtgtc tgccgagaag catcggagtg cgaggaagaa
2401 gggtttagca tttgtgtgga agtgaacggc aaggagcaga cgatgtctga gtgtgaggcg
2461 ggcgctctga gatgcagagg gcagagcatc tctgtcacca gcataaggcc ttgtgctgcg
2521 gaaacccagt aggctcctgg aggccatggt cagcttgctt ggaatccagc aggcagctgg
2581 ggctgagtga aaacatctgc acaactgggc actggacagc ttttccttct tctccagtgt
2641 ctaccttcct cctcaactcc cagccatctg tataaacaca atcctttgtt ctcccaaatc
2701 tgaatcgaat tactcttttg cctccttttt aatgtcagta aggatatgag cctttgcaca
2761 ggctggctgc gtgttcttga aataggtgtt accttctctg ggccttggtt ttttaaaatc
2821 tgtaaaatta gaggattgca ctagagaaac ttgaatgctc cattcaggcc tatcatttta
2881 ttaagtatga ttgacacagc ccatgggcca gaacacactc tacaaaatga ctaggataac
2941 agaaagaacg tgatctcctg attagagagg gtggttttcc tcaatggaac caaatataaa
3001 gaggacttga acaaaaatga cagatacaaa ctatttctat cctgagtagt aatctcacac
3061 ttcatcctat agagtcaacc accacagata ggaattcctt attctttttt taattttttt
3121 aagacagagt ctcactttgt tgcccaggct ggagcgcagt ggggtgatct catctccctg
3181 caacctccgc ctcctgggtt gaagcgattc ttgtgcctca gcttcccaag cagctgggat
3241 tacaggtgcc cgccaccacg cccagctaat ttttgcattt ttagtagaga tgggtttcac
3301 catgttggcc atgctcgtct ccaactcctg acctcaggta atccgtctgc cttggcctcc
3361 caaatgctgg gattacagac atgaaccacc acgcctggct ggaatactta ctcttgtcgg
3421 gagattgaac cactaaaatg ttagagcaga attcattatg ctgtggtcac aggggtgtct
3481 tgtctgagaa caaatacaat tcagtcttct ctttggggtt ttagtatgtg tcaaacatag
3541 gactggaagt ttgcccctgt tcttttttct tttgaaagaa catcagttca tgcctgaggc
3601 atgagtgact gtgcatttga gatagttttc cctattctgt ggatacagtc ccagagtttt
3661 cagggagtac acaggtagat tagtttgaag cattgacctt ttatttattc cttatttctc
3721 tttcatcaaa acaaaacagc agctgtggga ggagaaatga gagggcttaa atgaaattta
3781 aaataagcta tattatacaa atactatctc tgtattgttc tgaccctggt aaatatattt
3841 caaaacttca gatgacaagg attagaacac tcattaagat gctattcttc
//