LOCUS HUMLPDH 2314 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human lipoamide dehydrogenase mRNA, complete cds.
ACCESSION J03490
VERSION J03490.1
KEYWORDS lipoamide dehydrogenase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2314)
AUTHORS Otulakowski,G. and Robinson,B.H.
TITLE Isolation and sequence determination of cDNA clones for porcine and
human lipoamide dehydrogenase. Homology to other disulfide
oxidoreductases
JOURNAL J. Biol. Chem. 262 (36), 17313-17318 (1987)
PUBMED 3693355
COMMENT Original source text: Human lung small cell, cDNA to mRNA, clone
LD24.
Draft entry and computer readable sequence for [1] kindly by G.
Otulakowski, 08-MAR-1988.
FEATURES Location/Qualifiers
source 1..2314
/db_xref="H-InvDB:HIT000191161"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="7"
gene 1..2314
/gene="ZP3"
CDS 77..1606
/gene="ZP3"
/note="lipoamide dehydrogenase precursor old gene name
'LAD'"
/codon_start=1
/protein_id="AAA59527.1"
/db_xref="GDB:G00-128-007"
/translation="MQSWSRVYCSLAKRGHFNRISHGLQGLSAVPLRTYADQPIDADV
TVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHMAH
GTDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGKN
QVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVV
IGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNT
KVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPR
GRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSV
IYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRV
LGAHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSIN
F"
sig_peptide 77..184
/gene="ZP3"
/note="lipoamide dehydrogenase signal protein"
mat_peptide 182..1603
/gene="ZP3"
/product="lipoamide dehydrogenase"
BASE COUNT 712 a 372 c 532 g 698 t
ORIGIN 163 bp upstream of PstI site; chromosome 7.
1 ggaggggaga ccttggcgga cggcggagcc ccagcggagg tgaaagtatt ggcggaaagg
61 aaaatacagc ggaaaaatgc agagctggag tcgtgtgtac tgctccttgg ccaagagagg
121 ccatttcaat cgaatatctc atggcctaca gggactttct gcagtgcctc tgagaactta
181 cgcagatcag ccgattgatg ctgatgtaac agttataggt tctggtcctg gaggatatgt
241 tgctgctatt aaagctgccc agttaggctt caagacagtc tgcattgaga aaaatgaaac
301 acttggtgga acatgcttga atgttggttg tattccttct aaggctttat tgaacaactc
361 tcattattac catatggccc atggaacaga ttttgcatct agaggaattg aaatgtccga
421 agttcgcttg aatttagaca agatgatgga gcagaagagt actgcagtaa aagctttaac
481 aggtggaatt gcccacttat tcaaacagaa taaggttgtt catgtcaatg gatatggaaa
541 gataactggc aaaaatcaag tcactgctac gaaagctgat ggcggcactc aggttattga
601 tacaaagaac attcttatag ccacgggttc agaagttact ccttttcctg gaatcacgat
661 agatgaagat acaatagtgt catctacagg tgctttatct ttaaaaaaag ttccagaaaa
721 gatggttgtt attggtgcag gagtaatagg tgtagaattg ggttcagttt ggcaaagact
781 tggtgcagat gtgacagcag ttgaattttt aggtcatgta ggtggagttg gaattgatat
841 ggagatatct aaaaactttc aacgcatcct tcaaaaacag gggtttaaat ttaaattgaa
901 tacaaaggtt actggtgcta ccaagaagtc agatggaaaa attgatgttt ctattgaagc
961 tgcttctggt ggtaaagctg aagttatcac ttgtgatgta ctcttggttt gcattggccg
1021 acgacccttt actaagaatt tgggactaga agagctggga attgaactag atcctagagg
1081 tagaattcca gtcaatacca gatttcaaac taaaattcca aatatctatg ccattggtga
1141 tgtagttgct ggtccaatgc tggctcacaa agcagaggat gaaggcatta tctgtgttga
1201 aggaatggct ggtggtgctg tgcacattga ctacaattgt gtgccatcag tgatttacac
1261 acaccctgaa gttgcttggg ttggcaaatc agaagagcag ttgaaagaag agggtattga
1321 gtacaaagtt gggaaattcc catttgctgc taacagcaga gctaagacaa atgctgacac
1381 agatggcatg gtgaagatcc ttgggcagaa atcgacagac agagtactgg gagcacatat
1441 tcttggacca ggtgctggag aaatggtaaa tgaagctgct cttgctttgg aatatggagc
1501 atcctgtgaa gatatagcta gagtctgtca tgcacatccg accttatcag aagcttttag
1561 agaagcaaat cttgctgcgt catttggcaa atcaatcaac ttttgaatta gaagattata
1621 tatttttttt tctgaaattt cctgggagct tttgtagaag tcacattcct gaacaggata
1681 ttctcacagc tccaagaatt tctaggactg aattatgaaa cttttggaag gtatttaata
1741 ggtttggaca aaatggaata ctcttatatc tatattttac ataaatttag tattttgttt
1801 cagtgcacta atatgtaaga caaaaaggac tacttattgt agtcatcctg gaatatctcc
1861 gtcaactcat attttcatgc tgttcatgaa agattcaatg cccctgaatt taaatagctc
1921 ttttctctga tacagaaaag ttgaatttta catggctgga gctagaattt gatatgtgaa
1981 cagttgtgtt tgaagcacag tgatcaagtt atttttaatt tggttttcac attggaaaca
2041 agtcagtcat tcagatatga ttcaaatgtc tataaaccaa actgatgtaa gtaaatggtc
2101 tctcacttgt tttatttaac ctctaaattc tttcatttta ggggtagcat ttgtgttgaa
2161 gaggttttaa agcttccatt gttgtctgca actctgaagg gtaattatat agttacccaa
2221 attaagagag tctatttacg gaactcaaat acgtgggcat tcaaatgtat tacagtgggg
2281 aatgaagata ctgaaataaa cgtcttaaat attc
//