LOCUS HUMGNAZ 2679 bp mRNA linear HUM 08-NOV-1994
DEFINITION Human transducin alpha-subunit (GNAZ) mRNA, complete cds.
ACCESSION J03260
VERSION J03260.1
KEYWORDS guanine nucleotide-binding regulatory protein; transducin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2679)
AUTHORS Fong,H.K., Yoshimoto,K.K., Eversole-Cire,P. and Simon,M.I.
TITLE Identification of a GTP-binding protein alpha subunit that lacks an
apparent ADP-ribosylation site for pertussis toxin
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85 (9), 3066-3070 (1988)
PUBMED 3129724
COMMENT Original source text: Human retina, cDNA to mRNA, clone
lambda-alpha-161.
Draft entry and printed copy of sequence for [1] kindly provided by
H.K.W.Fong, 07-APR-1988.
FEATURES Location/Qualifiers
source 1..2679
/db_xref="H-InvDB:HIT000191151"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="22q11.1-q11.2"
gene 1..2679
/gene="GNAZ"
mRNA <1..2679
/gene="GNAZ"
/product="GNAZ mRNA"
CDS 13..1080
/gene="GNAZ"
/note="transducin alpha-subunit"
/codon_start=1
/protein_id="AAA52580.1"
/db_xref="GDB:G00-120-003"
/translation="MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNS
GKSTIVKQMKIIHSGGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAY
DAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDL
ERIAAADYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEG
VTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLA
EKIRRIPLTICFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQ
FVFDAVTDVIIQNNLKYIGLC"
BASE COUNT 650 a 728 c 700 g 601 t
ORIGIN 647 bp upstream of BamHI site.
1 gagaccagga ccatgggatg tcggcaaagc tcagaggaaa aagaagcagc ccggcggtcc
61 cggagaattg accgccacct gcgctcagag agccagcggc aacgccgcga aatcaagctg
121 ctcctgctgg gcaccagcaa ctcaggcaag agcaccatcg tcaaacagat gaagatcatc
181 cacagcggcg gcttcaacct ggaggcctgc aaggagtaca agcccctcat catctacaat
241 gccatcgact cgctgacccg catcatccgg gccctggccg ccctcaggat cgacttccac
301 aaccccgacc gcgcctacga cgctgtgcag ctctttgcgc tgacgggccc cgctgagagc
361 aagggcgaga tcacacccga gctgctgggt gtcatgcgac ggctctgggc cgacccaggg
421 gcacaggcct gcttcagccg ctccagcgag taccacctgg aggacaacgc ggcctactac
481 ctgaacgacc tggagcgcat cgccgcagct gactatatcc ccactgtcga ggacatcctg
541 cgctcccggg acatgaccac gggcattgtg gagaacaagt tcaccttcaa ggagctcacc
601 ttcaagatgg tggacgtggg ggggcagagg tcagagcgca aaaagtggat ccactgcttc
661 gagggcgtca cagccatcat cttctgtgtg gagctcagcg gctacgacct gaaactctac
721 gaggataacc agacaagtcg gatggcagag agcttgcgcc tctttgactc catctgcaac
781 aacaactggt tcatcaacac ctcactcatc ctcttcctga acaagaagga cctgctggca
841 gagaagatcc gccgcatccc gctcaccatc tgctttcccg agtacaaggg ccagaacacg
901 tacgaggagg ccgctgtcta catccagcgg cagtttgaag acctgaaccg caacaaggag
961 accaaggaga tctactccca cttcacctgc gccaccgaca ccagtaacat ccagtttgtc
1021 ttcgacgcgg tgacagacgt catcatacag aacaatctca agtacattgg cctttgctga
1081 ggagctgggc ccggggcgcc tgcctatggt gaaacccacg gggtgtcatg ccccaacgcg
1141 tgctagagag gcccaatcca ggggcagaaa acagggggcc taaagaatgt cccccacccc
1201 ttggcctctg cctccttggc cccacatttc tgcaaacata aatatttacg gatagattgc
1261 taggtagata gacacacaca catgcacaca cacacatctg gagatggcaa aatcctctaa
1321 aatgtcgagg tctcttgaag acttgagaag ctgtcacaag gtcactacaa gcccaacctg
1381 ccccttcact ttgccttcct gagttggccc cactccactt gggggtctgc attggattgt
1441 tagggatagg cagcagggct gaggcaaggt aggccaactg cacccctgtc acctggagga
1501 gggccggctc gctgcccgag ctctggccta gggaccttgc cgctgaccaa gagggaggac
1561 cagtgcaggg tctgtgcacc ttccctgctg gcctgcacac agctgctcag caccatttca
1621 ttctggacct gggaccttag gagccgggtg acagcactaa ccagacctcc agccactcac
1681 agctcttttt aaaaaacagc ttcaaaatat gcagcaaaaa ccaatacaac aaaacgagtg
1741 gcacgattta tttcaaacta ggccagctgg gattccagct tttcttctac tagtctgatg
1801 ttttataaat caaaacctgg ttttccttct ctggcatttt tttttgtttt ttgttttttg
1861 gttttttttt tttttttggc caaatctcgt ggtgtttcgc agaaaaaaat ccagaaaatt
1921 tcaaatgcag ttgagtattc ttttttaaat gcagattttc aaaacatatt ttttttcagg
1981 tggtcttttt tgtgtctggc ttgctgagtg taaaagttgt tatctggacg atctgtctct
2041 ctgctccaaa gaaattttgg agtgagtggc agtcctgcgc cagcctcgcg ggacacgtgt
2101 tgtacataag cctctgcagt gtcctcttgt taatggtggg gttttctgct ttgtttttat
2161 ttaagaaaat aaacacgaca tatttaaaga aggttctttc acctgggagc aaatgaacaa
2221 tagctaagtg tcttggtatt taaagagtaa attatttgtg gctttgctga gtgaaggaag
2281 gggagcaagg ggtggtgccc ctggtcccag catgccccgc gcctgagact ggctggaaat
2341 gctctgactc ctgtgaaggc acagccagcg ttgtggcctg agggaggccc tgctgggacc
2401 ctgatctggg ccttcctgtc ccagggccta tgggcaactg cgttgaaagg acgttcgcca
2461 agggccgtgt gtaaatacga actgcgccat ggagaggaga ggcactgccg gagcccttgc
2521 cagatctccc tccctctctc tgtgcagtag ctgtgtgtcc gaggtcagtg tgcggaatca
2581 cagccaagga cgtgaagaga tgtacggggg aaagagaagc tggggattgg atgaaagtca
2641 aaggttgtct actttaagaa aataaaatac cctgaatgg
//