LOCUS HUMVDR 4604 bp mRNA linear HUM 14-JAN-1995
DEFINITION Human vitamin D receptor mRNA, complete cds.
ACCESSION J03258
VERSION J03258.1
KEYWORDS vitamin D receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4604)
AUTHORS Baker,A.R., McDonnell,D.P., Hughes,M., Crisp,T.M.,
Mangelsdorf,D.J., Haussler,M.R., Pike,J.W., Shine,J. and
O'Malley,B.W.
TITLE Cloning and expression of full-length cDNA encoding human vitamin D
receptor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85 (10), 3294-3298 (1988)
PUBMED 2835767
COMMENT Original source text: Human jejunum, cDNA to mRNA, clones
lambda-VDR-[1,2] and VDR-3.
FEATURES Location/Qualifiers
source 1..4604
/db_xref="H-InvDB:HIT000191149"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="12q12-q14"
gene 1..4604
/gene="VDR"
mRNA <1..4604
/gene="VDR"
/product="VDR mRNA"
CDS 116..1399
/gene="VDR"
/note="vitamin D receptor"
/codon_start=1
/protein_id="AAA61273.1"
/db_xref="GDB:G00-120-487"
/translation="MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGC
KGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQR
KREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVN
DGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVT
LELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSN
ESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLM
AICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRS
LNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS"
BASE COUNT 1114 a 1278 c 1197 g 1015 t
ORIGIN 347 bp upstream of StuI site.
1 ggaacagctt gtccacccgc cggccggacc agaagccttt gggtctgaag tgtctgtgag
61 acctcacaga agagcacccc tgggctccac ttacctgccc cctgctcctt cagggatgga
121 ggcaatggcg gccagcactt ccctgcctga ccctggagac tttgaccgga acgtgccccg
181 gatctgtggg gtgtgtggag accgagccac tggctttcac ttcaatgcta tgacctgtga
241 aggctgcaaa ggcttcttca ggcgaagcat gaagcggaag gcactattca cctgcccctt
301 caacggggac tgccgcatca ccaaggacaa ccgacgccac tgccaggcct gccggctcaa
361 acgctgtgtg gacatcggca tgatgaagga gttcattctg acagatgagg aagtgcagag
421 gaagcgggag atgatcctga agcggaagga ggaggaggcc ttgaaggaca gtctgcggcc
481 caagctgtct gaggagcagc agcgcatcat tgccatactg ctggacgccc accataagac
541 ctacgacccc acctactccg acttctgcca gttccggcct ccagttcgtg tgaatgatgg
601 tggagggagc catccttcca ggcccaactc cagacacact cccagcttct ctggggactc
661 ctcctcctcc tgctcagatc actgtatcac ctcttcagac atgatggact cgtccagctt
721 ctccaatctg gatctgagtg aagaagattc agatgaccct tctgtgaccc tagagctgtc
781 ccagctctcc atgctgcccc acctggctga cctggtcagt tacagcatcc aaaaggtcat
841 tggctttgct aagatgatac caggattcag agacctcacc tctgaggacc agatcgtact
901 gctgaagtca agtgccattg aggtcatcat gttgcgctcc aatgagtcct tcaccatgga
961 cgacatgtcc tggacctgtg gcaaccaaga ctacaagtac cgcgtcagtg acgtgaccaa
1021 agccggacac agcctggagc tgattgagcc cctcatcaag ttccaggtgg gactgaagaa
1081 gctgaacttg catgaggagg agcatgtcct gctcatggcc atctgcatcg tctccccaga
1141 tcgtcctggg gtgcaggacg ccgcgctgat tgaggccatc caggaccgcc tgtccaacac
1201 actgcagacg tacatccgct gccgccaccc gcccccgggc agccacctgc tctatgccaa
1261 gatgatccag aagctagccg acctgcgcag cctcaatgag gagcactcca agcagtaccg
1321 ctgcctctcc ttccagcctg agtgcagcat gaagctaacg ccccttgtgc tcgaagtgtt
1381 tggcaatgag atctcctgac taggacagcc tgtgcggtgc ctgggtgggg ctgctcctcc
1441 agggccacgt gccaggcccg gggctggcgg ctactcagca gccctcctca cccgtctggg
1501 gttcagcccc tcctctgcca cctcccctat ccacccagcc cattctctct cctgtccaac
1561 ctaacccctt tcctgcgggc ttttccccgg tcccttgaga cctcagccat gaggagttgc
1621 tgtttgtttg acaaagaaac ccaagtgggg gcagagggca gaggctggag gcaggccttg
1681 cccagagatg cctccaccgc tgcctaagtg gctgctgact gatgttgagg gaacagacag
1741 gagaaatgca tccattcctc agggacagag acacctgcac ctccccccac tgcaggcccc
1801 gcttgtccag cgcctagtgg ggtctccctc tcctgcctta ctcacgataa ataatcggcc
1861 cacagctccc accccacccc cttcagtgcc caccaacatc ccattgccct ggttatattc
1921 tcacgggcag tagctgtggt gaggtgggtt ttcttcccat cactggagca ccaggcacga
1981 acccacctgc tgagagaccc aaggaggaaa aacagacaaa aacagcctca cagaagaata
2041 tgacagctgt ccctgtcacc aagctcacag ttcctcgccc tgggtctaag gggttggttg
2101 aggtggaagc cctccttcca cggatccatg tagcaggact gaattgtccc cagtttgcag
2161 aaaagcacct gccgacctcg tcctccccct gccagtgcct tacctcctgc ccaggagagc
2221 cagccctccc tgtcctcctc ggatcaccga gagtagccga gagcctgctc ccccaccccc
2281 tccccagggg agagggtctg gagaagcagt gagccgcatc ttctccatct ggcagggtgg
2341 gatggaggag aagaattttc agaccccagc ggctgagtca tgatctccct gccgcctcaa
2401 tgtggttgca aggccgctgt tcaccacagg gctaagagct aggctgccgc accccagagt
2461 gtgggaaggg agagcggggc agtctcgggt ggctagtcag agagagtgtt tgggggttcc
2521 gtgatgtagg gtaaggtgcc ttcttattct cactccacca cccaaaagtc aaaaggtgcc
2581 tgtgaggcag gggcggagtg atacaacttc aagtgcatgc tctctgcagg tcgagcccag
2641 cccagctggt gggaagcgtc tgtccgttta ctccaaggtg ggtctttgtg agagtgagct
2701 gtaggtgtgc gggaccggta cagaaaggcg ttcttcgagg tggatcacag aggcttcttc
2761 agatcaatgc ttgagtttgg aatcggccgc attccctgag tcaccaggaa tgttaaagtc
2821 agtgggaacg tgactgcccc aactcctgga agctgtgtcc ttgcacctgc atccgtagtt
2881 ccctgaaaac ccagagagga atcagacttc acactgcaag agccttggtg tccacctggc
2941 cccatgtctc tcagaattct tcaggtggaa aaacatctga aagccacgtt ccttactgca
3001 gaatagcata tatatcgctt aatcttaaat ttattagata tgagttgttt tcagactcag
3061 actccatttg tattatagtc taatatacag ggtagcaggt accactgatt tggagatatt
3121 tatgggggga gaacttacat tgtgaaactt ctgtacatta attattattg ctgttgttat
3181 tttacaaggg tctagggaga gacccttgtt tgattttagc tgcagaactg tattggtcca
3241 gcttgctctt cagtgggaga aaaacacttg taagttgcta aacgagtcaa tcccctcatt
3301 caggaaaact gacagaggag ggcgtgactc acccaagcca tatataacta gctagaagtg
3361 ggccaggaca ggccgggcgc ggtggctcac gcctgtaatc ccagcagttt gggaggtcga
3421 ggtaggtgga tcacctgagg tcgggagttc gagaccaacc tgaccaacat ggagaaaccc
3481 tgtctctatt aaaaatacaa aaaaaaaaaa aaaaaaaaat agccgggcat ggtggcgcaa
3541 gcctgtaatc ccagctactc aggaggctga ggcagaagaa ttgaacccag gaggtggagg
3601 ttgcagtgag ctgagatcgt gccgttactc tccaacctgg acaacaagag cgaaactccg
3661 tcttagaagt ggaccaggac aggaccagat tttggagtca tggtccggtg tccttttcac
3721 tacaccatgt ttgagctcag acccccactc tcattcccca ggtggctgac ccagtccctg
3781 ggggaagccc tggatttcag aaagagccaa gtctggatct gggacccttt ccttccttcc
3841 ctggcttgta actccaccaa gcccatcaga aggagaagga aggagactca cctctgcctc
3901 aatgtgaatc agaccctacc ccaccacgat gtgccctggc tgctgggctc tccacctcag
3961 gccttggata atgctgttgc ctcatctata acatgcattt gtctttgtaa tgtcaccacc
4021 ttcccagctc tccctctggc cctgcttctt cggggaactc ctgaaatatc agttactcag
4081 ccctgggccc caccacctag gccactcctc caaaggaagt ctaggagctg ggaggaaaag
4141 aaaagagggg aaaatgagtt tttatggggc tgaacgggga gaaaaggtca tcatcgattc
4201 tactttagaa tgagagtgtg aaatagacat ttgtaaatgt aaaactttta aggtatatca
4261 ttataactga aggagaaggt gccccaaaat gcaagatttt ccacaagatt cccagagaca
4321 ggaaaatcct ctggctggct aactggaagc atgtaggaga atccaagcga ggtcaacaga
4381 gaaggcagga atgtgtggca gatttagtga aagctagaga tatggcagcg aaaggatgta
4441 aacagtgcct gctgaatgat ttccaaagag aaaaaaagtt tgccagaagt ttgtcaagtc
4501 aaccaatgta gaaagctttg cttatggtaa taaaaatggc tcatacttat atagcactta
4561 ctttgtttgc aagtactgct gtaaataaat gctttatgca aacc
//