LOCUS HUMBCAT 1895 bp mRNA linear HUM 27-APR-1993
DEFINITION Human branched chain acyltransferase mRNA, complete cds.
ACCESSION J03208 J04723
VERSION J03208.1
KEYWORDS branched chain acyltransferase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 937)
AUTHORS Hummel,K.B., Litwer,S., Bradford,A.P., Aitken,A., Danner,D.J. and
Yeaman,S.J.
TITLE Nucleotide sequence of a cDNA for branched chain acyltransferase
with analysis of the deduced protein structure
JOURNAL J. Biol. Chem. 263 (13), 6165-6168 (1988)
PUBMED 3245861
REFERENCE 2 (bases 1 to 1895)
AUTHORS Danner,D.J., Litwer,S., Herring,W.J. and Pruckler,J.
TITLE Construction and nucleotide sequence of a cDNA encoding the
full-length preprotein for human branched chain acyltransferase
JOURNAL J. Biol. Chem. 264 (13), 7742-7746 (1989)
PUBMED 2708389
COMMENT Original source text: Human liver, cDNA to mRNA, clone pSL5.
[2] revises [1].
Draft entry and computer-readable sequence for [1,2] kindly
provided by D.J.Danner, 12-FEB-1988, 22-FEB-1989.
FEATURES Location/Qualifiers
source 1..1895
/db_xref="H-InvDB:HIT000191138"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 14..1447
/note="branched chain acyltransferase precursor"
/codon_start=1
/protein_id="AAA35589.1"
/translation="MLRTWSRNAGKLICVRYFQTCGNVHVLKPNYVCFFGYPSFKYSH
PHHFLKTTAALRGQVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKAS
VTITSRYDGVIKKLYYNLDDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQE
IKGRKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKV
EIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMVKTMSAALKIPHFGYCDE
IDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYK
ASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFT
LSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVI
DGATMSRFSNLWKSYLENPAFMLLDLK"
sig_peptide 14..175
/note="branched chain acyltransferase signal peptide"
mat_peptide 176..1444
/product="branched chain acyltransferase"
BASE COUNT 571 a 370 c 413 g 541 t
ORIGIN 7 bp upstream of PstI site.
1 cgctgcagtc cgtatgctga gaacctggag caggaatgcg gggaagctga tttgtgttcg
61 ctattttcaa acatgtggta atgttcatgt tttgaagcca aattatgtgt gtttctttgg
121 ttatccttca ttcaagtata gtcatccaca tcacttcctg aaaacaactg ctgctctccg
181 tggacaggtt gttcagttca agctctcaga cattggagaa gggattagag aagtaactgt
241 taaagaatgg tatgtaaaag aaggagatac agtgtctcag tttgatagca tctgtgaagt
301 tcaaagtgat aaagcttctg ttaccatcac tagtcgttat gatggagtca ttaaaaaact
361 ctattataat ctagacgata ttgcctatgt ggggaagcca ttagtagaca tagaaacgga
421 agctttaaaa gattcagaag aagatgttgt tgaaactcct gcagtgtctc atgatgaaca
481 tacacaccaa gagataaagg gccgaaaaac actggcaact cctgcagttc gccgtctggc
541 aatggaaaac aatattaagc tgagtgaagt tgttggctca ggaaaagatg gcagaatact
601 taaagaagat atcctcaact atttggaaaa gcagacagga gctatattgc ctccttcacc
661 caaagttgaa attatgccac ctccaccaaa gccaaaagac atgactgttc ctatactagt
721 atcaaaacct ccggtattca caggcaaaga caaaacagaa cccataaaag gctttcaaaa
781 agcaatggtc aagactatgt ctgcagccct gaagatacct cattttggtt attgtgatga
841 gattgacctt actgaactgg ttaagctccg agaagaatta aaacccattg catttgctcg
901 tggaattaaa ctctccttta tgcctttctt cttaaaggct gcttccttgg gattactaca
961 gtttcctatc cttaacgctt ctgtggatga aaactgccag aatataacat ataaggcttc
1021 tcataacatt gggatagcaa tggatactga gcagggtttg attgtcccta atgtgaaaaa
1081 tgttcagatc tgctctatat ttgacatcgc cactgaactg aaccgcctcc agaaattggg
1141 ctctgtgggt cagctcagca ccactgatct tacaggagga acatttactc tttccaacat
1201 tggatcaatt ggtggtacct ttgccaaacc agtgataatg ccacctgaag tagccattgg
1261 ggcccttgga tcaattaagg ccattccccg atttaaccag aaaggagaag tatataaggc
1321 acagataatg aatgtgagct ggtcagctga tcacagagtt attgatggtg ctacaatgtc
1381 acgcttctcc aatttgtgga aatcctattt agaaaaccca gcttttatgc tactagatct
1441 gaaatgaaga ctgataagac attcttgaac tttttgagct tccaaagagt atgtaaaccc
1501 tagctgtgcc agcacatgtt catctttaca atttatattg taaacgattt gtatcgtatg
1561 attaaggatc taaggcacaa tatttgtcac tgttctatta gactttttac tgaaaatgaa
1621 taatggtgta atggttctcc tggggctgtc acattttata ggtcagagtg tgacttctta
1681 atatggtgct gatgtttttg tgtcaatggc ttgaaactgg caagattaac aaaattaggc
1741 cgggcatggt ggctcacgcc tgtaatccag cactttggga ggcccaggtg gggcgatcac
1801 ctgaggttag aagtttgaga ccagcctggc caacatggtg aaacctggcc tctacctaaa
1861 aaatacaaaa ttgaccgggt gtggtggtgg gtacc
//