LOCUS HUMGKAS 2313 bp mRNA linear HUM 27-APR-1993
DEFINITION Human stimulatory G protein (of receptor-regulated K+ channels)
alpha subunit mRNA, complete cds.
ACCESSION J03198
VERSION J03198.1
KEYWORDS G protein; stimulatory G of adenylyl cyclase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2313)
AUTHORS Codina,J., Olate,J., Abramowitz,J., Mattera,R., Cook,R.G. and
Birnbaumer,L.
TITLE Alpha i-3 cDNA encodes the alpha subunit of Gk, the stimulatory G
protein of receptor-regulated K+ channels
JOURNAL J. Biol. Chem. 263 (14), 6746-6750 (1988)
PUBMED 2452165
COMMENT Original source text: Human liver, cDNA to mRNA, clones
lambda-a/ptx-[2.1,39].
FEATURES Location/Qualifiers
source 1..2313
/db_xref="H-InvDB:HIT000191136"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA <1..2313
/product="G as mRNA"
CDS 63..1127
/note="G protein alpha subunit"
/codon_start=1
/protein_id="AAA35896.1"
/translation="MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGES
GKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARAD
DARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLD
RISQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGV
TAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEE
KIKRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQF
VFDAVTDVIIKNNLKECGLY"
BASE COUNT 686 a 422 c 495 g 710 t
ORIGIN
1 ccgagccgca gtttccgtgt tgtgagtgag tccgggcccg tgtcccctct cccgccgccg
61 ccatgggctg cacgttgagc gccgaagaca aggcggcagt ggagcgaagc aagatgatcg
121 accgcaactt acgggaggac ggggaaaaag cggccaaaga agtgaagctg ctgctactcg
181 gtgctggaga atctggtaaa agcaccattg tgaaacagat gaaaatcatt catgaggatg
241 gctattcaga ggatgaatgt aaacaatata aagtagttgt ctacagcaat actatacagt
301 ccatcattgc aatcataaga gccatgggac ggctaaagat tgactttggg gaagctgcca
361 gggcagatga tgcccggcaa ttatttgttt tagctggcag tgctgaagaa ggagtcatga
421 ctccagaact agcaggagtg attaaacggt tatggcgaga tggtggggta caagcttgct
481 tcagcagatc cagggaatat cagctcaatg attctgcttc atattatcta aatgatctgg
541 atagaatatc ccagtctaac tacattccaa ctcagcaaga tgttcttcgg acgagagtga
601 agaccacagg cattgtagaa acacatttca ccttcaaaga cctatacttc aagatgtttg
661 atgtaggtgg ccaaagatca gaacgaaaaa agtggattca ctgttttgag ggagtgacag
721 caattatctt ctgtgtggcc ctcagtgatt atgaccttgt tctggctgag gacgaggaga
781 tgaaccgaat gcatgaaagc atgaaactgt ttgacagcat ttgtaataac aaatggttta
841 cagaaacttc aatcattctc ttccttaaca agaaagacct ttttgaggaa aaaataaaga
901 ggagtccgtt aactatctgt tatccagaat acacaggttc caatacatat gaagaggcag
961 ctgcctatat tcaatgccag tttgaagatc tgaacagaag aaaagatacc aaggagatct
1021 atactcactt cacctgtgcc acagacacga agaatgtgca gtttgttttt gatgctgtta
1081 cagatgtcat cattaaaaac aacttaaagg aatgtggact ttattgagaa gcatggatgt
1141 tagtgaaagt tactacagtg tggagtgttg agaccagaca ccttttgctg tctcatgggg
1201 cagctacaag catgaacggg accagggaat ggcagcagca tgcagaatct tagcactctt
1261 tagcacaata ttttgtatta gggaactttt aattgacatg agatgctaaa gtcagacatt
1321 ggaattggaa gaactataaa gtgtgattcg atcgtcaaga catcacttgg atttcttaat
1381 cttaaatgct tatggaagat gtgaagttga ggtgctgcat tctagaactt caatatgtag
1441 cttactcttt ttttcccccc ttcttaaacc accagtggtt catttttaag gttttttcat
1501 caagagaaga ataactttac taaattttat ttctttattt gcaaaagaat ctttattaaa
1561 acaaacaatc ttaactatgc acatgatgtg accagatcat cttgaaaata ttcctcttta
1621 gtaggaactc tttgttttta actcttggta tggtcagaat ataatacttc cataattact
1681 tataattctt tccggttact ggggctataa atacaacttt ttaaatgaaa tttatgttat
1741 tatcctgctc aaagtaccat tatggtttcc atatggtaat tacattggaa agttctgcaa
1801 taagattcta gttctctctt ttctttaagc ttatggttga aggttaacct tgtttgtgca
1861 gattaccaaa ttactgctga tgtagtatga taaagtcagc ttcttggata cagacacacc
1921 cagggcagct gccaatcaga aatgcaaatt gctaaattcc aaacagaacc agtgactttg
1981 ctgctacata tttactaaat tgaccacttt gattcttgct tgtttgtctc agttataggg
2041 agttttgtac atggtgcctc ttgttttcca tcttcatggc cttttctgtt gagaaacatc
2101 taaagtgtat taacagtgca tgcttttact ttgtaaatgt ggtgccaaat ccctgtttgc
2161 catcgttttt actgtaccga tgttaactgt agtaatcctt agccagtatg ttcttttgct
2221 gaaactgttg cattttggga cttttttcca ctttgtcatg tgtacatttt taatctgtta
2281 tagttggcgg cagtattaaa atggtgagta aag
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