LOCUS HUMTFSP1 2655 bp mRNA linear HUM 14-JAN-1995
DEFINITION Human transcription factor SP1 mRNA, 3' end.
ACCESSION J03133
VERSION J03133.1
KEYWORDS transcription factor SP1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2655)
AUTHORS Kadonaga,J.T., Carner,K.R., Masiarz,F.R. and Tjian,R.
JOURNAL Unpublished
REFERENCE 2 (sites)
AUTHORS Kadonaga,J.T., Carner,K.R., Masiarz,F.R. and Tjian,R.
TITLE Isolation of cDNA encoding transcription factor Sp1 and functional
analysis of the DNA binding domain
JOURNAL Cell 51 (6), 1079-1090 (1987)
PUBMED 3319186
COMMENT Original source text: Human HeLa cell, cDNA to mRNA, (library of
C.Hauser), clone Sp1-1.
[2] sites; binding domains.
Draft entry and computer-readable sequence for [1] kindly provided
by J.T.Kadonaga, 17-NOV-1987.
FEATURES Location/Qualifiers
source 1..2655
/db_xref="H-InvDB:HIT000191130"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="12q"
gene 1..2655
/gene="SP1"
CDS <1..2091
/gene="SP1"
/note="transcription factor Sp-1"
/codon_start=1
/protein_id="AAA61154.1"
/db_xref="GDB:G00-127-453"
/translation="TGELDLTATQLSQGANGWQIISSSSGATPTSKEQSGSSTNGSNG
SESSKNRTVSGGQYVVAAAPNLQNQQVLTGLPGVMPNIQYQVIPQFQTVDGQQLQFAA
TGAQVQQDGSGQIQIIPGANQQIITNRGSGGNIIAAMPNLLQQAVPLQGLANNVLSGQ
TQYVTNVPVALNGNITLLPVNSVSAATLTPSSQAVTISSSGSQESGSQPVTSGTTISS
ASLVSSQASSSSFFTNANSYSTTTTTSNMGIMNFTTSGSSGTNSQGQTPQRVSGLQGS
DALNIQQNQTSGGSLQAGQQKEGEQNQQTQQQQILIQPQLVQGGQALQALQAAPLSGQ
TFTTQAISQETLQNLQLQAVPNSGPIIIRTPTVGPNGQVSWQTLQLQNLQVQNPQAQT
ITLAPMQGVSLGQTSSSNTTLTPIASAASIPAGTVTVNAAQLSSMPGLQTINLSALGT
SGIQVHPIQGLPLAIANAPGDHGAQLGLHGAGGDGIHDDTAGGEEGENSPDAQPQAGR
RTRREACTCPYCKDSEGRGSGDPGKKKQHICHIQGCGKVYGKTSHLRAHLRWHTGERP
FMCTWSYCGKRFTRSDELQRHKRTHTGEKKFACPECPKRFMRSDHLSKHIKTHQNKKG
GPGVALSVGTLPLDSGAGSEGSGTATPSALITTNMVAMEAICPEGIARLANSGINVMQ
VADLQSINISGNGF"
BASE COUNT 717 a 726 c 630 g 582 t
ORIGIN 540 bp upstream of HincII site.
1 acaggtgagc ttgacctcac agccacacaa ctttcacagg gtgccaatgg ctggcagatc
61 atctcttcct cctctggggc tacccctacc tcaaaggaac agagtggcag cagtaccaat
121 ggcagcaatg gcagtgagtc ttccaagaat cgcacagtct ctggtgggca gtatgttgtg
181 gctgccgctc ccaacttaca gaaccagcaa gttctgacag gactacctgg agtgatgcct
241 aatattcagt atcaagtaat cccacagttc cagaccgttg atgggcaaca gctgcagttt
301 gctgccactg gggcccaagt gcagcaggat ggttctggtc aaatacagat cataccaggt
361 gcaaaccaac agattatcac aaatcgagga agtggaggca acatcattgc tgctatgcca
421 aacctactcc agcaggctgt ccccctccaa ggcctggcta ataatgtact ctcaggacag
481 actcagtatg tgaccaatgt accagtggcc ctgaatggga acatcacctt gctacctgtc
541 aacagcgttt ctgcagctac cttgactccc agctctcagg cagtcacgat cagcagctct
601 gggtcccagg agagtggctc acagcctgtc acctcaggga ctaccatcag ttctgccagc
661 ttggtatcat cacaagccag ttccagctcc tttttcacca atgccaatag ctactcaact
721 actactacca ccagcaacat gggaattatg aactttacta ccagtggatc atcagggacc
781 aactctcaag gccagacacc ccagagggtc agtgggctac aggggtctga tgctctgaac
841 atccagcaaa accagacatc tggaggctca ttgcaagcag gccagcaaaa agaaggagag
901 caaaaccagc agacacagca gcaacaaatt cttatccagc ctcagctagt tcaaggggga
961 caggccctcc aggccctcca agcagcacca ttgtcagggc agacctttac aactcaagcc
1021 atctcccagg aaaccctcca gaacctccag cttcaggctg ttccaaactc tggtcccatc
1081 atcatccgga caccaacagt ggggcccaat ggacaggtca gttggcagac tctacagctg
1141 cagaacctcc aagttcagaa cccacaagcc caaacaatca ccttagcccc aatgcagggt
1201 gtttccttgg ggcagaccag cagcagcaac accactctca cacccattgc ctcagctgct
1261 tccattcctg ctggcacagt cactgtgaat gctgctcaac tctcctccat gccaggcctc
1321 cagaccatta acctcagtgc attgggtact tcaggaatcc aggtgcaccc aattcaaggc
1381 ctgccgttgg ctatagcaaa tgccccaggt gatcatggag ctcagcttgg tctccatggg
1441 gctggtggtg atggaataca tgatgacaca gcaggtggag aggaaggaga aaacagccca
1501 gatgcccaac cccaagccgg tcggaggacc cggcgggaag catgcacctg cccctactgt
1561 aaagacagtg aaggaagggg ctcgggggat cctggcaaaa agaaacagca tatttgccac
1621 atccaaggct gtgggaaagt gtatggcaag acctctcacc tgcgggcaca cttgcgctgg
1681 catacaggcg agaggccatt tatgtgtacc tggtcatact gtgggaaacg cttcacacgt
1741 tcggatgagc tacagaggca caaacgtaca cacacaggtg agaagaaatt tgcctgccct
1801 gagtgtccta agcgcttcat gaggagtgac cacctgtcaa aacatatcaa gacccaccag
1861 aataagaagg gaggcccagg tgtagctctg agtgtgggca ctttgcccct ggacagtggg
1921 gcaggttcag aaggcagtgg cactgccact ccttcagccc ttattaccac caatatggta
1981 gccatggagg ccatctgtcc agagggcatt gcccgtcttg ccaacagtgg catcaacgtc
2041 atgcaggtgg cagatctgca gtccattaat atcagtggca atggcttctg agatcaggca
2101 cccggggcca gagacatatg ggccataccc cttaaccccg ggatgcaagg tagcatgggt
2161 ccaagagaca tggaagagag agccatgaag cattaaaatg catggtgttg agaagaatca
2221 ggagagggat acaagagagg agatggggtc ccggcaccca tctgtatcat cagtgcctct
2281 ttgaaggtgg gaaacattag tgaaaattct gttggtgcca cgctttgatg agcatttgtt
2341 tgaccccagt ttcttcttac acttcttacc ccagcctacc cttcctgcat ttctcttctc
2401 agctcttcca tgatggattc cccccccttt cctaaagcca tcatgccttg ataaatatat
2461 atgatcattg aaatactttt taacaaaaaa cagattctat attattatat atatatatat
2521 atataaagat atatagagat gcattcacag ggttggctgg agaggaagac cattctgtga
2581 ccaaaatacc ttggtcattt tttttatatt gccttatttc cctatggctg agccttgttg
2641 tgacacatca agctt
//