LOCUS HUMICAMA1M 2986 bp mRNA linear HUM 08-NOV-1994
DEFINITION Human intercellular adhesion molecule-1 (ICAM-1) mRNA, complete
cds.
ACCESSION J03132
VERSION J03132.1
KEYWORDS intercellular adhesion molecule-1.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2986)
AUTHORS Staunton,D.E., Marlin,S.D., Stratowa,C., Dustin,M.L. and
Springer,T.A.
TITLE Primary structure of ICAM-1 demonstrates interaction between
members of the immunoglobulin and integrin supergene families
JOURNAL Cell 52 (6), 925-933 (1988)
PUBMED 3349522
COMMENT Original source text: Human (patient with hairy cell leukemia)
spleen, cDNA to mRNA, clone HL-60.
Draft entry and printed copy of sequence for [1] kindly provided by
D.E.Staunton, 25-MAR-1988.
FEATURES Location/Qualifiers
source 1..2986
/db_xref="H-InvDB:HIT000191129"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="19p13.3-p13.2"
gene 1..2986
/gene="ICAM1"
mRNA <1..2986
/gene="ICAM1"
/product="ICAM-1 mRNA"
CDS 58..1656
/gene="ICAM1"
/note="intercellular adhesion molecule-1 precursor"
/codon_start=1
/protein_id="AAA52709.1"
/db_xref="GDB:G00-120-076"
/translation="MAPSSPRPALPALLVLLGALFPGPGNAQTSVSPSKVILPRGGSV
LVTCSTSCDQPKLLGIETPLPKKELLLPGNNRKVYELSNVQEDSQPMCYSNCPDGQST
AKTFLTVYWTPERVELAPLPSWQPVGKNLTLRCQVEGGAPRANLTVVLLRGEKELKRE
PAVGEPAEVTTTVLVRRDHHGANFSCRTELDLRPQGLELFENTSAPYQLQTFVLPATP
PQLVSPRVLEVDTQGTVVCSLDGLFPVSEAQVHLALGDQRLNPTVTYGNDSFSAKASV
SVTAEDEGTQRLTCAVILGNQSQETLQTVTIYSFPAPNVILTKPEVSEGTEVTVKCEA
HPRAKVTLNGVPAQPLGPRAQLLLKATPEDNGRSFSCSATLEVAGQLIHKNQTRELRV
LYGPRLDERDCPGNWTWPENSQQTPMCQAWGNPLPELKCLKDGTFPLPIGESVTVTRD
LEGTYLCRARSTQGEVTREVTVNVLSPRYEIVIITVVAAAVIMGTAGLSTYLYNRQRK
IKKYRLQQAQKGTPMKPNTQATPP"
sig_peptide 58..138
/gene="ICAM1"
/note="put. intercellular adhesion molecule-1 signal
peptide; putative"
mat_peptide 139..1653
/gene="ICAM1"
/product="intercellular adhesion molecule-1"
BASE COUNT 684 a 873 c 804 g 625 t
ORIGIN Unreported.
1 gcgccccagt cgacgctgag ctcctctgct actcagagtt gcaacctcag cctcgctatg
61 gctcccagca gcccccggcc cgcgctgccc gcactcctgg tcctgctcgg ggctctgttc
121 ccaggacctg gcaatgccca gacatctgtg tccccctcaa aagtcatcct gccccgggga
181 ggctccgtgc tggtgacatg cagcacctcc tgtgaccagc ccaagttgtt gggcatagag
241 accccgttgc ctaaaaagga gttgctcctg cctgggaaca accggaaggt gtatgaactg
301 agcaatgtgc aagaagatag ccaaccaatg tgctattcaa actgccctga tgggcagtca
361 acagctaaaa ccttcctcac cgtgtactgg actccagaac gggtggaact ggcacccctc
421 ccctcttggc agccagtggg caagaacctt accctacgct gccaggtgga gggtggggca
481 ccccgggcca acctcaccgt ggtgctgctc cgtggggaga aggagctgaa acgggagcca
541 gctgtggggg agcccgctga ggtcacgacc acggtgctgg tgaggagaga tcaccatgga
601 gccaatttct cgtgccgcac tgaactggac ctgcggcccc aagggctgga gctgtttgag
661 aacacctcgg ccccctacca gctccagacc tttgtcctgc cagcgactcc cccacaactt
721 gtcagccccc gggtcctaga ggtggacacg caggggaccg tggtctgttc cctggacggg
781 ctgttcccag tctcggaggc ccaggtccac ctggcactgg gggaccagag gttgaacccc
841 acagtcacct atggcaacga ctccttctcg gccaaggcct cagtcagtgt gaccgcagag
901 gacgagggca cccagcggct gacgtgtgca gtaatactgg ggaaccagag ccaggagaca
961 ctgcagacag tgaccatcta cagctttccg gcgcccaacg tgattctgac gaagccagag
1021 gtctcagaag ggaccgaggt gacagtgaag tgtgaggccc accctagagc caaggtgacg
1081 ctgaatgggg ttccagccca gccactgggc ccgagggccc agctcctgct gaaggccacc
1141 ccagaggaca acgggcgcag cttctcctgc tctgcaaccc tggaggtggc cggccagctt
1201 atacacaaga accagacccg ggagcttcgt gtcctgtatg gcccccgact ggacgagagg
1261 gattgtccgg gaaactggac gtggccagaa aattcccagc agactccaat gtgccaggct
1321 tgggggaacc cattgcccga gctcaagtgt ctaaaggatg gcactttccc actgcccatc
1381 ggggaatcag tgactgtcac tcgagatctt gagggcacct acctctgtcg ggccaggagc
1441 actcaagggg aggtcacccg cgaggtgacc gtgaatgtgc tctccccccg gtatgagatt
1501 gtcatcatca ctgtggtagc agccgcagtc ataatgggca ctgcaggcct cagcacgtac
1561 ctctataacc gccagcggaa gatcaagaaa tacagactac aacaggccca aaaagggacc
1621 cccatgaaac cgaacacaca agccacgcct ccctgaacct atcccgggac agggcctctt
1681 cctcggcctt cccatattgg tggcagtggt gccacactga acagagtgga agacatatgc
1741 catgcagcta cacctaccgg ccctgggacg ccggaggaca gggcattgtc ctcagtcaga
1801 tacaacagca tttggggcca tggtacctgc acacctaaaa cactaggcca cgcatctgat
1861 ctgtagtcac atgactaagc caagaggaag gagcaagact caagacatga ttgatggatg
1921 ttaaagtcta gcctgatgag aggggaagtg gtgggggaga catagcccca ccatgaggac
1981 atacaactgg gaaatactga aacttgctgc ctattgggta tgctgaggcc cacagactta
2041 cagaagaagt ggccctccat agacatgtgt agcatcaaaa cacaaaggcc cacacttcct
2101 gacggatgcc agcttgggca ctgctgtcta ctgaccccaa cccttgatga tatgtattta
2161 ttcatttgtt attttaccag ctatttattg agtgtctttt atgtaggcta aatgaacata
2221 ggtctctggc ctcacggagc tcccagtcca tgtcacattc aaggtcacca ggtacagttg
2281 tacaggttgt acactgcagg agagtgcctg gcaaaaagat caaatggggc tgggacttct
2341 cattggccaa cctgcctttc cccagaagga gtgatttttc tatcggcaca aaagcactat
2401 atggactggt aatggttcac aggttcagag attacccagt gaggccttat tcctcccttc
2461 cccccaaaac tgacaccttt gttagccacc tccccaccca catacatttc tgccagtgtt
2521 cacaatgaca ctcagcggtc atgtctggac atgagtgccc agggaatatg cccaagctat
2581 gccttgtcct cttgtcctgt ttgcatttca ctgggagctt gcactattgc agctccagtt
2641 tcctgcagtg atcagggtcc tgcaagcagt ggggaagggg gccaaggtat tggaggactc
2701 cctcccagct ttggaagggt catccgcgtg tgtgtgtgtg tgtatgtgta gacaagctct
2761 cgctctgtca cccaggctgg agtgcagtgg tgcaatcatg gttcactgca gtcttgacct
2821 tttgggctca agtgatcctc ccacctcagc ctcctgagta gctgggacca taggctcaca
2881 acaccacacc tggcaaattt gatttttttt ttttttttca gagacggggt ctcgcaacat
2941 tgcccagact tcctttgtgt tagttaataa agctttctca actgcc
//