LOCUS HUMCAIIA 1551 bp mRNA linear HUM 31-OCT-1994
DEFINITION Human carbonic anhydrase II mRNA, complete cds.
ACCESSION J03037
VERSION J03037.1
KEYWORDS carbonic anhydrase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1551)
AUTHORS Murakami,H., Marelich,G.P., Grubb,J.H., Kyle,J.W. and Sly,W.S.
TITLE Cloning, expression, and sequence homologies of cDNA for human
carbonic anhydrase II
JOURNAL Genomics 1 (2), 159-166 (1987)
PUBMED 3121496
COMMENT Original source text: Human kidney, cDNA to mRNA, (library of
G.I.Bell), clone lambda-HM3.
Draft entry and computer-readable sequence for [1] kindly provided
by R.D.Miller, 24-SEP-1987.
FEATURES Location/Qualifiers
source 1..1551
/db_xref="H-InvDB:HIT000191121"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="8q13-q22"
gene 1..1551
/gene="CA2"
mRNA <1..1551
/gene="CA2"
/product="CA II mRNA"
CDS 66..848
/gene="CA2"
/note="carbonic anhydrase II"
/codon_start=1
/protein_id="AAA51908.1"
/db_xref="GDB:G00-119-739"
/translation="MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSL
KPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDG
QGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVV
DVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVS
SEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK"
BASE COUNT 460 a 322 c 329 g 440 t
ORIGIN 238 bp upstream of BamHI site; chromosome 8q22.
1 ggcgcccaag ccgccgccgc cagatcggtg ccgattcctg ccctgccccg accgccagcg
61 cgaccatgtc ccatcactgg gggtacggca aacacaacgg acctgagcac tggcataagg
121 acttccccat tgccaaggga gagcgccagt cccctgttga catcgacact catacagcca
181 agtatgaccc ttccctgaag cccctgtctg tttcctatga tcaagcaact tccctgagga
241 tcctcaacaa tggtcatgct ttcaacgtgg agtttgatga ctctcaggac aaagcagtgc
301 tcaagggagg acccctggat ggcacttaca gattgattca gtttcacttt cactggggtt
361 cacttgatgg acaaggttca gagcatactg tggataaaaa gaaatatgct gcagaacttc
421 acttggttca ctggaacacc aaatatgggg attttgggaa agctgtgcag caacctgatg
481 gactggccgt tctaggtatt tttttgaagg ttggcagcgc taaaccgggc cttcagaaag
541 ttgttgatgt gctggattcc attaaaacaa agggcaagag tgctgacttc actaacttcg
601 atcctcgtgg cctccttcct gaatccctgg attactggac ctacccaggc tcactgacca
661 cccctcctct tctggaatgt gtgacctgga ttgtgctcaa ggaacccatc agcgtcagca
721 gcgagcaggt gttgaaattc cgtaaactta acttcaatgg ggagggtgaa cccgaagaac
781 tgatggtgga caactggcgc ccagctcagc cactgaagaa caggcaaatc aaagcttcct
841 tcaaataaga tggtcccata gtctgtatcc aaataatgaa tcttcgggtg tttcccttta
901 gctaagcaca gatctacctt ggtgatttgg accctggttg ctttgtgtct agttttctag
961 acccttcatc tcttacttga tagacttact aataaaatgt gaagactaga ccaattgtca
1021 tgcttgacac aactgctgtg gctggttggt gctttgttta tggtagtagt ttttctgtaa
1081 cacagaatat aggataagaa ataagaataa agtaccttga ctttgttcac agcatgtagg
1141 gtgatgagca ctcacaattg ttgactaaaa tgctgctttt aaaacatagg aaagtagaat
1201 ggttgagtgc aaatccatag cacaagataa attgagctag ttaaggcaaa tcaggtaaaa
1261 tagtcatgat tctatgtaat gtaaaccaga aaaaataaat gttcatgatt tcaagatgtt
1321 atattaaaga aaaactttaa aaattattat atatttatag caaagttatc ttaaatatga
1381 attctgttgt aatttaatga cttttgaatt acagagatat aaatgaagta ttatctgtaa
1441 aaattgttat aattagagtt gtgatacaga gtatatttcc attcagacaa tatatcataa
1501 cttaataaat attgtatttt agatatattc tctaataaaa ttcagaattc t
//