LOCUS HUMGIAA 1664 bp mRNA linear HUM 08-NOV-1994
DEFINITION Human guanine nucleotide-binding regulatory protein (G)
alpha-inhibitory-subunit mRNA, complete cds.
ACCESSION J03004
VERSION J03004.1
KEYWORDS guanine nucleotide-binding regulatory protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1664)
AUTHORS Beals,C.R., Wilson,C.B. and Perlmutter,R.M.
TITLE A small multigene family encodes Gi signal-transduction proteins
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 84 (22), 7886-7890 (1987)
PUBMED 3120178
COMMENT Original source text: Human fetal liver mononuclear cell, and
peripheral blood T-lymphocyte cell line PEER, cDNA to mRNA, clones
BT-12 and PR-15.
FEATURES Location/Qualifiers
source 1..1664
/db_xref="H-InvDB:HIT000191116"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="7q21-q22"
gene 1..1664
/gene="GNAI1"
mRNA <1..1664
/gene="GNAI1"
/product="GNAI1 mRNA"
CDS 78..1145
/gene="GNAI1"
/note="guanine nucleotide-binding regulatory protein
alpha-inhibitory subunit"
/codon_start=1
/protein_id="AAA52556.1"
/db_xref="GDB:G00-120-001"
/translation="MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGES
GKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRAD
DARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDL
ERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEG
VTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFE
EKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQ
FVFDAVTDXIIKNNLKDCGLF"
BASE COUNT 362 a 496 c 481 g 324 t
ORIGIN 1 bp upstream of EcoRI site; chromosome 7q21-q22.
1 gaattcgggt gggtcgggcg gggccgagcc gggccgtggg ccgtgtgggg gccgggcggc
61 ggccggcgga cggcgggatg ggctgcaccg tgagcgccga ggacaaggcg gcggccgagc
121 gctctaagat gatcgacaag aacctgcggg aggacggaga gaaggcggcg cgggaggtga
181 agttgctgct gttgggtgct ggggagtcag ggaagagcac catcgtcaag cagatgaaga
241 tcatccacga ggatggctac tccgaggagg aatgccggca gtaccgggcg gttgtctaca
301 gcaacaccat ccagtccatc atggccattg tcaaagccat gggcaacctg cagatcgact
361 ttgccgaccc ctccagagcg gacgacgcca ggcagctatt tgcactgtcc tgcaccgccg
421 aggagcaagg cgtgctccct gatgacctgt ccggcgtcat ccggaggctc tgggctgacc
481 atggtgtgca ggcctgcttt ggccgctcaa gggaatacca gctcaacgac tcagctgcct
541 actacctgaa cgacctggag cgtattgcac agagtgacta catccccaca cagcaagatg
601 tgctacggac ccgcgtaaag accacgggga tcgtggagac acacttcacc ttcaaggacc
661 tacacttcaa gatgtttgat gtgggtggtc agcggtctga gcggaagaag tggatccact
721 gctttgaggg cgtcacagcc atcatcttct gcgtagcctt gagcgcctat gacttggtgc
781 tagctgagga cgaggagatg aaccgcatgc atgagagcat gaagctattc gatagcatct
841 gcaacaacaa gtggttcaca gacacgtcca tcatcctctt cctcaacaag aaggacctgt
901 ttgaggagaa gatcacacac agtcccctga ccatctgctt ccctgagtac acaggggcca
961 acaaatatga tgaggcagcc agctacatcc agagtaagtt tgaggacctg aataagcgca
1021 aagacaccaa ggagatctac acgcacttca cgtgcgccac cgacaccaag aacgtgcagt
1081 tcgtgtttga cgccgtcacc gatgncatca tcaagaacaa cctgaaggac tgcggcctct
1141 tctgaggggc agcggggcct ggcgggtatg gccaccgccg actttgtacc ccccaacccc
1201 taggaagatg ggcaagaaga tcacgctccc cgcctgttcc cccgccgctt ttctcctctt
1261 tcctctcttt gttctcagct ccccctgtcc cctcagctcc agacgtaggg gaggggttcg
1321 cacaggcctc cctgtttgaa gcctgccctt gtctgagatg ctggtaatgg ccatggtacc
1381 cttctggctt atgttctggt ttttaacatt gtcttgtctg tgtatgaggg aggggcacat
1441 gctgtgatct ccaaggctgc gtctggaggg gcccctgctt ctccagcctg gacccccagc
1501 tttgcccaac accagcccct gccccagcca agtccaaatg tttacaggga gcctcctgcc
1561 cagtccccca ccccgccgcg cgggccccaa ggaaaaagca caagaacgtg agacgccacc
1621 attcctggaa accacagtcc acctgctcat tctcgtagct tttt
//