LOCUS HUMPLG2B 3303 bp mRNA linear HUM 07-JAN-1995
DEFINITION Human platelet membrane glycoprotein IIb (ITGA2B) mRNA, complete
cds.
ACCESSION J02764
VERSION J02764.1
KEYWORDS membrane adhesive protein; platelet membrane glycoprotein; platelet
receptor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3303)
AUTHORS Poncz,M., Eisman,R., Heidenreich,R., Silver,S.M., Vilaire,G.,
Surrey,S., Schwartz,E. and Bennett,J.S.
TITLE Structure of the platelet membrane glycoprotein IIb. Homology to
the alpha subunits of the vitronectin and fibronectin membrane
receptors
JOURNAL J. Biol. Chem. 262 (18), 8476-8482 (1987)
PUBMED 2439501
COMMENT Original source text: Human HEL cell, cDNA to mRNA.
Draft entry and computer-readable sequence [1] kindly provided by
M.Poncz, 15-APR-1987.
FEATURES Location/Qualifiers
source 1..3303
/db_xref="H-InvDB:HIT000191085"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/map="17q21.32"
gene 1..3303
/gene="ITGA2B"
mRNA <1..3303
/gene="ITGA2B"
/note="G00-120-012"
CDS 2..3121
/gene="ITGA2B"
/codon_start=1
/product="platelet membrane glycoprotein IIb"
/protein_id="AAA60114.1"
/db_xref="GDB:G00-120-012"
/translation="MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAG
PNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFD
LRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGS
CFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPG
GYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFD
GDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRAEQMASYFGHSVAVTDVNGDGR
HDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIA
PLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGF
SLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQ
TKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNL
DLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQ
EQTRIVLDSGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAV
HLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGN
LEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGE
REQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQ
CFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSA
PCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPP
LSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPP
LEEDDEEGE"
sig_peptide 2..94
/gene="ITGA2B"
/note="G00-120-012"
mat_peptide 95..3118
/gene="ITGA2B"
/product="platelet membrane glycoprotein IIb"
/note="G00-120-012"
BASE COUNT 618 a 997 c 1026 g 662 t
ORIGIN Unreported.
1 gatggccaga gctttgtgtc cactgcaagc cctctggctt ctggagtggg tgctgctgct
61 cttgggacct tgtgctgccc ctccagcctg ggccttgaac ctggacccag tgcagctcac
121 cttctatgca ggccccaatg gcagccagtt tggattttca ctggacttcc acaaggacag
181 ccatgggaga gtggccatcg tggtgggcgc cccgcggacc ctgggcccca gccaggagga
241 gacgggcggc gtgttcctgt gcccctggag ggccgagggc ggccagtgcc cctcgctgct
301 ctttgacctc cgtgatgaga cccgaaatgt aggctcccaa actttacaaa ccttcaaggc
361 ccgccaagga ctgggggcgt cggtcgtcag ctggagcgac gtcattgtgg cctgcgcccc
421 ctggcagcac tggaacgtcc tagaaaagac tgaggaggct gagaagacgc ccgtaggtag
481 ctgctttttg gctcagccag agagcggccg ccgcgccgag tactccccct gtcgcgggaa
541 caccctgagc cgcatttacg tggaaaatga ttttagctgg gacaagcgtt actgtgaagc
601 gggcttcagc tccgtggtca ctcaggccgg agagctggtg cttggggctc ctggcggcta
661 ttatttctta ggtctcctgg cccaggctcc agttgcggat attttctcga gttaccgccc
721 aggcatcctt ttgtggcacg tgtcctccca gagcctctcc tttgactcca gcaacccaga
781 gtacttcgac ggctactggg ggtactcggt ggccgtgggc gagttcgacg gggatctcaa
841 cactacagaa tatgtcgtcg gtgcccccac ttggagctgg accctgggag cggtggaaat
901 tttggattcc tactaccaga ggctgcatcg gctgcgcgca gagcagatgg cgtcgtattt
961 tgggcattca gtggctgtca ctgacgtcaa cggggatggg aggcatgatc tgctggtggg
1021 cgctccactg tatatggaga gccgggcaga ccgaaaactg gccgaagtgg ggcgtgtgta
1081 tttgttcctg cagccgcgag gcccccacgc gctgggtgcc cccagcctcc tgctgactgg
1141 cacacagctc tatgggcgat tcggctctgc catcgcaccc ctgggcgacc tcgaccggga
1201 tggctacaat gacattgcag tggctgcccc ctacgggggt cccagtggcc ggggccaagt
1261 gctggtgttc ctgggtcaga gtgaggggct gaggtcacgt ccctcccagg tcctggacag
1321 ccccttcccc acaggctctg cctttggctt ctcccttcga ggtgccgtag acatcgatga
1381 caacggatac ccagacctga tcgtgggagc ttacggggcc aaccaggtgg ctgtgtacag
1441 agctcagcca gtggtgaagg cctctgtcca gctactggtg caagattcac tgaatcctgc
1501 tgtgaagagc tgtgtcctac ctcagaccaa gacacccgtg agctgcttca acatccagat
1561 gtgtgttgga gccactgggc acaacattcc tcagaagcta tccctaaatg ccgagctgca
1621 gctggaccgg cagaagcccc gccagggccg gcgggtgctg ctgctgggct ctcaacaggc
1681 aggcaccacc ctgaacctgg atctgggcgg aaagcacagc cccatctgcc acaccaccat
1741 ggccttcctt cgagatgagg cagacttccg ggacaagctg agccccattg tgctcagcct
1801 caatgtgtcc ctaccgccca cggaggctgg aatggcccct gctgtcgtgc tgcatggaga
1861 cacccatgtg caggagcaga cacgaatcgt cctggactct ggggaagatg acgtatgtgt
1921 gccccagctt cagctcactg ccagcgtgac gggctccccg ctcctagttg gggcagataa
1981 tgtcctggag ctgcagatgg acgcagccaa cgagggcgag ggggcctatg aagcagagct
2041 ggccgtgcac ctgccccagg gcgcccacta catgcgggcc ctaagcaatg tcgagggctt
2101 tgagagactc atctgtaatc agaagaagga gaatgagacc agggtggtgc tgtgtgagct
2161 gggcaacccc atgaagaaga acgcccagat aggaatcgcg atgttggtga gcgtggggaa
2221 tctggaagag gctggggagt ctgtgtcctt ccagctgcag atacggagca agaacagcca
2281 gaatccaaac agcaagattg tgctgctgga cgtgccggtc cgggcagagg cccaagtgga
2341 gctgcgaggg aactcctttc cagcctccct ggtggtggca gcagaagaag gtgagaggga
2401 gcagaacagc ttggacagct ggggacccaa agtggagcac acctatgagc tccacaacaa
2461 tggccctggg actgtgaatg gtcttcacct cagcatccac cttccgggac agtcccagcc
2521 ctccgacctg ctctacatcc tggatataca gccccagggg ggccttcagt gcttcccaca
2581 gcctcctgtc aaccctctca aggtggactg ggggctgccc atccccagcc cctcccccat
2641 tcacccggcc catcacaagc gggatcgcag acagatcttc ctgccagagc ccgagcagcc
2701 ctcgaggctt caggatccag ttctcgtaag ctgcgactcg gcgccctgta ctgtggtgca
2761 gtgtgacctg caggagatgg cgcgcgggca gcgggccatg gtcacggtgc tggccttcct
2821 gtggctgccc agcctctacc agaggcctct ggatcagttt gtgctgcagt cgcacgcatg
2881 gttcaacgtg tcctccctcc cctatgcggt gcccccgctc agcctgcccc gaggggaagc
2941 tcaggtgtgg acacagctgc tccgggcctt ggaggagagg gccattccaa tctggtgggt
3001 gctggtgggt gtgctgggtg gcctgctgct gctcaccatc ctggtcctgg ccatgtggaa
3061 ggtcggcttc ttcaagcgga accggccacc cctggaagaa gatgatgaag agggggagtg
3121 atggtgcagc ctacactatt ctagcaggag ggttgggcgt gctacctgca ccgccccttc
3181 tccaacaagt tgcctccaag ctttgggttg gagctgttcc attgggtcct cttggtgtcg
3241 tttccctccc aacagagctg ggctaccccc cctcctgctg cctaataaag agactgagcc
3301 ctg
//