LOCUS HUMAPOBA 14070 bp mRNA linear HUM 27-APR-1993
DEFINITION Human apolipoprotein B-100 mRNA, complete cds.
ACCESSION J02610
VERSION J02610.1
KEYWORDS apolipoprotein B-100.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 14070)
AUTHORS Chen,S.H., Yang,C.Y., Chen,P.F., Setzer,D., Tanimura,M., Li,W.H.,
Gotto,A.M. Jr. and Chan,L.
TITLE The complete cDNA and amino acid sequence of human apolipoprotein
B-100
JOURNAL J. Biol. Chem. 261 (28), 12918-12921 (1986)
PUBMED 3759943
COMMENT Original source text: Human liver, cDNA to mRNA, 30 overlapping
clones.
Computer-readable sequence of [1] kindly provided by L.Chan
(03-SEP-1986). A polyadenylation signal can be found at positions
14043-14048.
FEATURES Location/Qualifiers
source 1..14070
/db_xref="H-InvDB:HIT000191071"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
mRNA <1..14070
/product="apoB-100 mRNA"
CDS 79..13770
/note="apolipoprotein B-100 precursor"
/codon_start=1
/protein_id="AAA35549.1"
/translation="MDPPRPALLALLALPALLLLLLAGARAEEEMLENVSLVCPKDAT
RFKHLRKYTYNYEAESSSGVPGTADSRSATRINCKVELEVPQLCSFILKTSQCILKEV
YGFNPEGKALLKKTKNSEEFAAAMSRYELKLAIPEGKQVFLYPEKDEPTYILNIKRGI
ISALLVPPETEEAKQVLFLDTVYGNCSTHFTVKTRKGNVATEISTERDLGQCDRFKPI
RTGISPLALIKGMTRPLSTLISSSQSCQYTLDAKRKHVAEAICKEQHLFLPFSYKNKY
GMVAQVTQTLKLEDTPKINSRFFGEGTKKMGLAFESTKSTSPPKQAEAVLKTVQELKK
LTISEQNIQRANLFNKLVTELRGLSDEAVTSLLPQLIEVSSPITLQALVQCGQPQCST
HILQWLKRVHANPLLIDVVTYLVALIPEPSAQQLREIFNMARDQRSRATLYALSHAVN
NYHKTNPTGTQELLDIANYLMEQIQDDCTGDEDYTYLILRVIGNMGQTMEQLTPELKS
SILKCVQSTKPSLMIQKAAIQALRKMEPKDKDQEVLLQTFLDDASPGDKRLAAYLMLM
RSPSQADINKIVQILPWEQNEQVKNFVASHIANILNSEELDIQDLKKLVKEVLKESQL
PTVMDFRKFSRNYQLYKSVSIPSLDPASAKIEGNLIFDPNNYLPKESMLKTTLTAFGF
ASADLIEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVNGQVPDGVSKVLVDHFGY
TKDDKHEQDMVNGIMLSVEKLIKDLKSKEVPEARAYLRILGEELGFASLHDLQLLGKL
LLMGARTLQGIPQMIGEVIRKGSKNDFFLHYIFMENAFELPTGAGLQLQISSSGVIAP
GAKAGVKLEVANMQAELVAKPSVSVEFVTNMGIIIPDFARSGVQMNTNFFHESGLEAH
VALKPGKLKFIIPSPKRPVKLLSGGNTLHLVSTTKTEVIPPLIENRQSWSVCKQVFPG
LNYCTSGAYSNASSTDSASYYPLTGDTRLELELRPTGEIEQYSVSATYELQREDRALV
DTLKFVTQAEGAKQTEATMTFKYNRQSMTLSSEVQIPDFDVDLGTILRVNDESTEGKT
SYRLTLDIQNKKITEVALMGHLSCDTKEERKIKGVISIPRLQAEARSEILAHWSPAKL
LLQMDSSATAYGSTVSKRVAWHYDEEKIEFEWNTGTNVDTKKMTSNFPVDLSDYPKSL
HMYANRLLDHRVPQTDMTFRHVGSKLIVAMSSWLQKASGSLPYTQTLQDHLNSLKEFN
LQNMGLPDFHIPENLFLKSDGRVKYTLNKNSLKIEIPLPFGGKSSRDLKMLETVRTPA
LHFKSVGFHLPSREFQVPTFTIPKLYQLQVPLLGVLDLSTNVYSNLYNWSASYSGGNT
STDHFSLRARYHMKADSVVDLLSYNVQGSGETTYDHKNTFTLSCDGSLRHKFLDSNIK
FSHVEKLGNNPVSKGLLIFDASSSWGPQMSASVHLDSKKKQHLFVKEVKIDGQFRVSS
FYAKGTYGLSCQRDPNTGRLNGESNLRFNSSYLQGTNQITGRYEDGTLSLTSTSDLQS
GIIKNTASLKYENYELTLKSDTNGKYKNFATSNKMDMTFSKQNALLRSEYQADYESLR
FFSLLSGSLNSHGLELNADILGTDKINSGAHKATLRIGQDGISTSATTNLKCSLLVLE
NELNAELGLSGASMKLTTNGRFREHNAKFSLDGKAALTELSLGSAYQAMILGVDSKNI
FNFKVSQEGLKLSNDMMGSYAEMKFDHTNSLNIAGLSLDFSSKLDNIYSSDKFYKQTV
NLQLQPYSLVTTLNSDLKYNALDLTNNGKLRLEPLKLHVAGNLKGAYQNNEIKHIYAI
SSAALSASYKADTVAKVQGVEFSHRLNTDIAGLASAIDMSTNYNSDSLHFSNVFRSVM
APFTMTIDAHTNGNGKLALWGEHTGQLYSKFLLKAEPLAFTFSHDYKGSTSHHLVSRK
SISAALEHKVSALLTPAEQTGTWKLKTQFNNNEYSQDLDAYNTKDKIGVELTGRTLAD
LTLLDSPIKVPLLLSEPINIIDALEMRDAVEKPQEFTIVAFVKYDKNQDVHSINLPFF
ETLQEYFERNRQTIIVVLENVQRNLKHINIDQFVRKYRAALGKLPQQANDYLNSFNWE
RQVSHAKEKLTALTKKYRITENDIQIALDDAKINFNEKLSQLQTYMIQFDQYIKDSYD
LHDLKIAIANIIDEIIEKLKSLDEHYHIRVNLVKTIHDLHLFIENIDFNKSGSSTASW
IQNVDTKYQIRIQIQEKLQQLKRHIQNIDIQHLAGKLKQHIEAIDVRVLLDQLGTTIS
FERINDVLEHVKHFVINLIGDFEVAEKINAFRAKVHELIERYEVDQQIQVLMDKLVEL
AHQYKLKETIQKLSNVLQQVKIKDYFEKLVGFIDDAVKKLNELSFKTFIEDVNKFLDM
LIKKLKSFDYHQFVDETNDKIREVTQRLNGEIQALELPQKAEALKLFLEETKATVAVY
LESLQDTKITLIINWLQEALSSASLAHMKAKFRETLEDTRDRMYQMDIQQELQRYLSL
VGQVYSTLVTYISDWWTLAAKNLTDFAEQYSIQDWAKRMKALVEQGFTVPEIKTILGT
MPAFEVSLQALQKATFQTPDFIVPLTDLRIPSVQINFKDLKNIKIPSRFSTPEFTILN
TFHIPSFTIDFVEMKVKIIRTIDQMLNSELQWPVPDIYLRDLKVEDIPLARITLPDFR
LPEIAIPEFIIPTLNLNDFQVPDLHIPEFQLPHISHTIEVPTFGKLYSILKIQSPLFT
LDANADIGNGTTSANEAGIAASITAKGESKLEVLNFDFQANAQLSNPKINPLALKESV
KFSSKYLRTEHGSEMLFFGNAIEGKSNTVASLHTEKNTLELSNGVIVKINNQLTLDSN
TKYFHKLNIPKLDFSSQADLRNEIKTLLKAGHIAWTSSGKGSWKWACPRFSDEGTHES
QISFTIEGPLTSFGLSNKINSKHLRVNQNLVYESGSLNFSKLEIQSQVDSQHVGHSVL
TAKGMALFGEGKAEFTGRHDAHLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVRF
PLRLTGKIDFLNNYALFLSPSAQQASWQVSARFNQYKYNQNFSAGNNENIMEAHVGIN
GEANLDFLNIPLTIPEMRLPYTIITTPPLKDFSLWEKTGLKEFLKTTKQSFDLSVKAQ
YKKNKHRHSITNPLAVLCEFISQSIKSFDRHFEKNRNNALDFVTKSYNETKIKFDKYK
AEKSHDELPRTFQIPGYTVPVVNVEVSPFTIEMSAFGYVFPKAVSMPSFSILGSDVRV
PSYTLILPSLELPVLHVPRNLKLSLPDFKELCTISHIFIPAMGNITYDFSFKSSVITL
NTNAELFNQSDIVAHLLSSSSSVIDALQYKLEGTTRLTRKRGLKLATALSLSNKFVEG
SHNSTVSLTTKNMEVSVATTTKAQIPILRMNFKQELNGNTKSKPTVSSSMEFKYDFNS
SMLYSTAKGAVDHKLSLESLTSYFSIESSTKGDVKGSVLSREYSGTIASEANTYLNSK
STRSSVKLQGTSKIDDIWNLEVKENFAGEATLQRIYSLWEHSTKNHLQLEGLFFTNGE
HTSKATLELSPWQMSALVQVHASQPSSFHDFPDLGQEVALNANTKNQKIRWKNEVRIH
SGSFQSQVELSNDQEKAHLDIAGSLEGHLRFLKNIILPVYDKSLWDFLKLDVTTSIGR
RQHLRVSTAFVYTKNPNGYSFSIPVKVLADKFIIPGLKLNDLNSVLVMPTFHVPFTDL
QVPSCKLDFREIQIYKKLRTSSFALNLPTLPEVKFPEVDVLTKYSQPEDSLIPFFEIT
VPESQLTVSQFTLPKSVSDGIAALDLNAVANKIADFELPTIIVPEQTIEIPSIKFSVP
AGIAIPSFQALTARFEVDSPVYNATWSASLKNKADYVETVLDSTCSSTVQFLEYELNV
LGTHKIEDGTLASKTKGTFAHRDFSAEYEEDGKYEGLQEWEGKAHLNIKSPAFTDLHL
RYQKDKKGISTSAASPAVGTVGMDMDEDDDFSKWNFYYSPQSSPDKKLTIFKTELRVR
ESDEETQIKVNWEEEAASGLLTSLKDNVPKATGVLYDYVNKYHWEHTGLTLREVSSKL
RRNLQDHAEWVYQGAIREIDDIDERFQKGASGTTGTYQEWKDKAQNLYQELLTQEGQA
SFQGLKDNVFDGLVRVTQEFHMKVKHLIDSLIDFLNFPRFQFPGKPGIYTREELCTMF
IREVGTVLSQVYSKVHNGSEILFSYFQDLVITLPFELRKHKLIDVISMYRELLKDLSK
EAQEVFKAIQSLKTTEVLRNLQDLLQFIFQLIEDNIKQLKEMKFTYLINYIQDEINTI
FNDYIPYVFKLLKENLCLNLHKFNEFIQNELQEASQELQQIHQYIMALREEYFDPSIV
GWTVKYYELEEKIVSLIKNLLVALKDFHSEYIVSASNFTSQLSSQVEQFLHRNIQEYL
SILTDPDGKGKEKIAELSATAQEIIKSQAIATKKIISDYHQQFRYKLQDFSDQLSDYY
EKFIAESKRLIDLSIQNYHTFLIYITELLKKLQSTTVMNPYMKLAPGELTIIL"
sig_peptide 79..159
/note="apolipoprotein B-100 signal pept"
mat_peptide 160..13767
/product="apolipoprotein B-100"
BASE COUNT 4363 a 3217 c 2892 g 3598 t
ORIGIN
1 gaggagcccg cccagccagc cagggccgcg aggccgaggc caggccgcag cccaggagcc
61 gccccaccgc agctggcgat ggacccgccg aggcccgcgc tgctggcgct gctggcgctg
121 cctgcgctgc tgctgctgct gctggcgggc gccagggccg aagaggaaat gctggaaaat
181 gtcagcctgg tctgtccaaa agatgcgacc cgattcaagc acctccggaa gtacacatac
241 aactatgagg ctgagagttc cagtggagtc cctgggactg ctgattcaag aagtgccacc
301 aggatcaact gcaaggttga gctggaggtt ccccagctct gcagcttcat cctgaagacc
361 agccagtgca tcctgaaaga ggtgtatggc ttcaaccctg agggcaaagc cttgctgaag
421 aaaaccaaga actctgagga gtttgctgca gccatgtcca ggtatgagct caagctggcc
481 attccagaag ggaagcaggt tttcctttac ccggagaaag atgaacctac ttacatcctg
541 aacatcaaga ggggcatcat ttctgccctc ctggttcccc cagagacaga agaagccaag
601 caagtgttgt ttctggatac cgtgtatgga aactgctcca ctcactttac cgtcaagacg
661 aggaagggca atgtggcaac agaaatatcc actgaaagag acctggggca gtgtgatcgc
721 ttcaagccca tccgcacagg catcagccca cttgctctca tcaaaggcat gacccgcccc
781 ttgtcaactc tgatcagcag cagccagtcc tgtcagtaca cactggacgc taagaggaag
841 catgtggcag aagccatctg caaggagcaa cacctcttcc tgcctttctc ctacaagaat
901 aagtatggga tggtagcaca agtgacacag actttgaaac ttgaagacac accaaagatc
961 aacagccgct tctttggtga aggtactaag aagatgggcc tcgcatttga gagcaccaaa
1021 tccacatcac ctccaaagca ggccgaagct gttttgaaga ctgtccagga actgaaaaaa
1081 ctaaccatct ctgagcaaaa tatccagaga gctaatctct tcaataagct ggttactgag
1141 ctgagaggcc tcagtgatga agcagtcaca tctctcttgc cacagctgat tgaggtgtcc
1201 agccccatca ctttacaagc cttggttcag tgtggacagc ctcagtgctc cactcacatc
1261 ctccagtggc tgaaacgtgt gcatgccaac ccccttctga tagatgtggt cacctacctg
1321 gtggccctga tccccgagcc ctcagcacag cagctgcgag agatcttcaa catggcgagg
1381 gatcagcgca gccgagccac cttgtatgcg ctgagccacg cggtcaacaa ctatcataag
1441 acaaacccta cagggaccca ggagctgctg gacattgcta attacctgat ggaacagatt
1501 caagatgact gcactgggga tgaagattac acctatttga ttctgcgggt cattggaaat
1561 atgggccaaa ccatggagca gttaactcca gaactcaagt cttcaatcct gaaatgtgtc
1621 caaagtacaa agccatcact gatgatccag aaagctgcca tccaggctct gcggaaaatg
1681 gagcctaaag acaaggacca ggaggttctt cttcagactt tccttgatga tgcttctccg
1741 ggagataagc gactggctgc ctatcttatg ttgatgagga gtccttcaca ggcagatatt
1801 aacaaaattg tccaaattct accatgggaa cagaatgagc aagtgaagaa ctttgtggct
1861 tcccatattg ccaatatctt gaactcagaa gaattggata tccaagatct gaaaaagtta
1921 gtgaaagaag ttctgaaaga atctcaactt ccaactgtca tggacttcag aaaattctct
1981 cggaactatc aactctacaa atctgtttct attccatcac ttgacccagc ctcagccaaa
2041 atagaaggga atcttatatt tgatccaaat aactaccttc ctaaagaaag catgctgaaa
2101 actaccctca ctgcctttgg atttgcttca gctgacctca tcgagattgg cttggaagga
2161 aaaggctttg agccaacatt ggaagctctt tttgggaagc aaggattttt cccagacagt
2221 gtcaacaaag ctttgtactg ggttaatggt caagttcctg atggtgtctc taaggtctta
2281 gtggaccact ttggctatac caaagatgat aaacatgagc aggatatggt aaatggaata
2341 atgctcagtg ttgagaagct gattaaagat ttgaaatcca aagaagtccc ggaagccaga
2401 gcctacctcc gcatcttggg agaggagctt ggttttgcca gtctccatga cctccagctc
2461 ctgggaaagc tgcttctgat gggtgcccgc actctgcagg ggatccccca gatgattgga
2521 gaggtcatca ggaagggctc aaagaatgac ttttttcttc actacatctt catggagaat
2581 gcctttgaac tccccactgg agctggatta cagttgcaaa tatcttcatc tggagtcatt
2641 gctcccggag ccaaggctgg agtaaaactg gaagtagcca acatgcaggc tgaactggtg
2701 gcaaaaccct ccgtgtctgt ggagtttgtg acaaatatgg gcatcatcat tccggacttc
2761 gctaggagtg gggtccagat gaacaccaac ttcttccacg agtcgggtct ggaggctcat
2821 gttgccctaa aacctgggaa gctgaagttt atcattcctt ccccaaagag accagtcaag
2881 ctgctcagtg gaggcaacac attacatttg gtctctacca ccaaaacgga ggtgatccca
2941 cctctcattg agaacaggca gtcctggtca gtttgcaagc aagtctttcc tggcctgaat
3001 tactgcacct caggcgctta ctccaacgcc agctccacag actccgcctc ctactatccg
3061 ctgaccgggg acaccagatt agagctggaa ctgaggccta caggagagat tgagcagtat
3121 tctgtcagcg caacctatga gctccagaga gaggacagag ccttggtgga taccctgaag
3181 tttgtaactc aagcagaagg tgcgaagcag actgaggcta ccatgacatt caaatataat
3241 cggcagagta tgaccttgtc cagtgaagtc caaattccgg attttgatgt tgacctcgga
3301 acaatcctca gagttaatga tgaatctact gagggcaaaa cgtcttacag actcaccctg
3361 gacattcaga acaagaaaat tactgaggtc gccctcatgg gccacctaag ttgtgacaca
3421 aaggaagaaa gaaaaatcaa gggtgttatt tccatacccc gtttgcaagc agaagccaga
3481 agtgagatcc tcgcccactg gtcgcctgcc aaactgcttc tccaaatgga ctcatctgct
3541 acagcttatg gctccacagt ttccaagagg gtggcatggc attatgatga agagaagatt
3601 gaatttgaat ggaacacagg caccaatgta gataccaaaa aaatgacttc caatttccct
3661 gtggatctct ccgattatcc taagagcttg catatgtatg ctaatagact cctggatcac
3721 agagtccctc aaacagacat gactttccgg cacgtgggtt ccaaattaat agttgcaatg
3781 agctcatggc ttcagaaggc atctgggagt cttccttata cccagacttt gcaagaccac
3841 ctcaatagcc tgaaggagtt caacctccag aacatgggat tgccagactt ccacatccca
3901 gaaaacctct tcttaaaaag cgatggccgg gtcaaatata ccttgaacaa gaacagtttg
3961 aaaattgaga ttcctttgcc ttttggtggc aaatcctcca gagatctaaa gatgttagag
4021 actgttagga caccagccct ccacttcaag tctgtgggat tccatctgcc atctcgagag
4081 ttccaagtcc ctacttttac cattcccaag ttgtatcaac tgcaagtgcc tctcctgggt
4141 gttctagacc tctccacgaa tgtctacagc aacttgtaca actggtccgc ctcctacagt
4201 ggtggcaaca ccagcacaga ccatttcagc cttcgggctc gttaccacat gaaggctgac
4261 tctgtggttg acctgctttc ctacaatgtg caaggatctg gagaaacaac atatgaccac
4321 aagaatacgt tcacactatc atgtgatggg tctctacgcc acaaatttct agattcgaat
4381 atcaaattca gtcatgtaga aaaacttgga aacaacccag tctcaaaagg tttactaata
4441 ttcgatgcat ctagttcctg gggaccacag atgtctgctt cagttcattt ggactccaaa
4501 aagaaacagc atttgtttgt caaagaagtc aagattgatg ggcagttcag agtctcttcg
4561 ttctatgcta aaggcacata tggcctgtct tgtcagaggg atcctaacac tggccggctc
4621 aatggagagt ccaacctgag gtttaactcc tcctacctcc aaggcaccaa ccagataaca
4681 ggaagatatg aagatggaac cctctccctc acctccacct ctgatctgca aagtggcatc
4741 attaaaaata ctgcttccct aaagtatgag aactacgagc tgactttaaa atctgacacc
4801 aatgggaagt ataagaactt tgccacttct aacaagatgg atatgacctt ctctaagcaa
4861 aatgcactgc tgcgttctga atatcaggct gattacgagt cattgaggtt cttcagcctg
4921 ctttctggat cactaaattc ccatggtctt gagttaaatg ctgacatctt aggcactgac
4981 aaaattaata gtggtgctca caaggcgaca ctaaggattg gccaagatgg aatatctacc
5041 agtgcaacga ccaacttgaa gtgtagtctc ctggtgctgg agaatgagct gaatgcagag
5101 cttggcctct ctggggcatc tatgaaatta acaacaaatg gccgcttcag ggaacacaat
5161 gcaaaattca gtctggatgg gaaagccgcc ctcacagagc tatcactggg aagtgcttat
5221 caggccatga ttctgggtgt cgacagcaaa aacattttca acttcaaggt cagtcaagaa
5281 ggacttaagc tctcaaatga catgatgggc tcatatgctg aaatgaaatt tgaccacaca
5341 aacagtctga acattgcagg cttatcactg gacttctctt caaaacttga caacatttac
5401 agctctgaca agttttataa gcaaactgtt aatttacagc tacagcccta ttctctggta
5461 actactttaa acagtgacct gaaatacaat gctctggatc tcaccaacaa tgggaaacta
5521 cggctagaac ccctgaagct gcatgtggct ggtaacctaa aaggagccta ccaaaataat
5581 gaaataaaac acatctatgc catctcttct gctgccttat cagcaagcta taaagcagac
5641 actgttgcta aggttcaggg tgtggagttt agccatcggc tcaacacaga catcgctggg
5701 ctggcttcag ccattgacat gagcacaaac tataattcag actcactgca tttcagcaat
5761 gtcttccgtt ctgtaatggc cccgtttacc atgaccatcg atgcacatac aaatggcaat
5821 gggaaactcg ctctctgggg agaacatact gggcagctgt atagcaaatt cctgttgaaa
5881 gcagaacctc tggcatttac tttctctcat gattacaaag gctccacaag tcatcatctc
5941 gtgtctagga aaagcatcag tgcagctctt gaacacaaag tcagtgccct gcttactcca
6001 gctgagcaga caggcacctg gaaactcaag acccaattta acaacaatga atacagccag
6061 gacttggatg cttacaacac taaagataaa attggcgtgg agcttactgg acgaactctg
6121 gctgacctaa ctctactaga ctccccaatt aaagtgccac ttttactcag tgagcccatc
6181 aatatcattg atgctttaga gatgagagat gccgttgaga agccccaaga atttacaatt
6241 gttgcttttg taaagtatga taaaaaccaa gatgttcact ccattaacct cccatttttt
6301 gagaccttgc aagaatattt tgagaggaat cgacaaacca ttatagttgt actggaaaac
6361 gtacagagaa acctgaagca catcaatatt gatcaatttg taagaaaata cagagcagcc
6421 ctgggaaaac tcccacagca agctaatgat tatctgaatt cattcaattg ggagagacaa
6481 gtttcacatg ccaaggagaa actgactgct ctcacaaaaa agtatagaat tacagaaaat
6541 gatatacaaa ttgcattaga tgatgccaaa atcaacttta atgaaaaact atctcaactg
6601 cagacatata tgatacaatt tgatcagtat attaaagata gttatgattt acatgatttg
6661 aaaatagcta ttgctaatat tattgatgaa atcattgaaa aattaaaaag tcttgatgag
6721 cactatcata tccgtgtaaa tttagtaaaa acaatccatg atctacattt gtttattgaa
6781 aatattgatt ttaacaaaag tggaagtagt actgcatcct ggattcaaaa tgtggatact
6841 aagtaccaaa tcagaatcca gatacaagaa aaactgcagc agcttaagag acacatacag
6901 aatatagaca tccagcacct agctggaaag ttaaaacaac acattgaggc tattgatgtt
6961 agagtgcttt tagatcaatt gggaactaca atttcatttg aaagaataaa tgatgttctt
7021 gagcatgtca aacactttgt tataaatctt attggggatt ttgaagtagc tgagaaaatc
7081 aatgccttca gagccaaagt ccatgagtta atcgagaggt atgaagtaga ccaacaaatc
7141 caggttttaa tggataaatt agtagagttg gcccaccaat acaagttgaa ggagactatt
7201 cagaagctaa gcaatgtcct acaacaagtt aagataaaag attactttga gaaattggtt
7261 ggatttattg atgatgctgt caagaagctt aatgaattat cttttaaaac attcattgaa
7321 gatgttaaca aattccttga catgttgata aagaaattaa agtcatttga ttaccaccag
7381 tttgtagatg aaaccaatga caaaatccgt gaggtgactc agagactcaa tggtgaaatt
7441 caggctctgg aactaccaca aaaagctgaa gcattaaaac tgtttttaga ggaaaccaag
7501 gccacagttg cagtgtatct ggaaagccta caggacacca aaataacctt aatcatcaat
7561 tggttacagg aggctttaag ttcagcatct ttggctcaca tgaaggccaa attccgagag
7621 actctagaag atacacgaga ccgaatgtat caaatggaca ttcagcagga acttcaacga
7681 tacctgtctc tggtaggcca ggtttatagc acacttgtca cctacatttc tgattggtgg
7741 actcttgctg ctaagaacct tactgacttt gcagagcaat attctatcca agattgggct
7801 aaacgtatga aagcattggt agagcaaggg ttcactgttc ctgaaatcaa gaccatcctt
7861 gggaccatgc ctgcctttga agtcagtctt caggctcttc agaaagctac cttccagaca
7921 cctgatttta tagtccccct aacagatttg aggattccat cagttcagat aaacttcaaa
7981 gacttaaaaa atataaaaat cccatccagg ttttccacac cagaatttac catccttaac
8041 accttccaca ttccttcctt tacaattgac tttgtagaaa tgaaagtaaa gatcatcaga
8101 accattgacc agatgctgaa cagtgagctg cagtggcccg ttccagatat atatctcagg
8161 gatctgaagg tggaggacat tcctctagcg agaatcaccc tgccagactt ccgtttacca
8221 gaaatcgcaa ttccagaatt cataatccca actctcaacc ttaatgattt tcaagttcct
8281 gaccttcaca taccagaatt ccagcttccc cacatctcac acacaattga agtacctact
8341 tttggcaagc tatacagtat tctgaaaatc caatctcctc ttttcacatt agatgcaaat
8401 gctgacatag ggaatggaac cacctcagca aacgaagcag gtatcgcagc ttccatcact
8461 gccaaaggag agtccaaatt agaagttctc aattttgatt ttcaagcaaa tgcacaactc
8521 tcaaacccta agattaatcc gctggctctg aaggagtcag tgaagttctc cagcaagtac
8581 ctgagaacgg agcatgggag tgaaatgctg ttttttggaa atgctattga gggaaaatca
8641 aacacagtgg caagtttaca cacagaaaaa aatacactgg agcttagtaa tggagtgatt
8701 gtcaagataa acaatcagct taccctggat agcaacacta aatacttcca caaattgaac
8761 atccccaaac tggacttctc tagtcaggct gacctgcgca acgagatcaa gacactgttg
8821 aaagctggcc acatagcatg gacttcttct ggaaaagggt catggaaatg ggcctgcccc
8881 agattctcag atgagggaac acatgaatca caaattagtt tcaccataga aggacccctc
8941 acttcctttg gactgtccaa taagatcaat agcaaacacc taagagtaaa ccaaaacttg
9001 gtttatgaat ctggctccct caacttttct aaacttgaaa ttcaatcaca agtcgattcc
9061 cagcatgtgg gccacagtgt tctaactgct aaaggcatgg cactgtttgg agaagggaag
9121 gcagagttta ctgggaggca tgatgctcat ttaaatggaa aggttattgg aactttgaaa
9181 aattctcttt tcttttcagc ccagccattt gagatcacgg catccacaaa caatgaaggg
9241 aatttgaaag ttcgttttcc attaaggtta acagggaaga tagacttcct gaataactat
9301 gcactgtttc tgagtcccag tgcccagcaa gcaagttggc aagtaagtgc taggttcaat
9361 cagtataagt acaaccaaaa tttctctgct ggaaacaacg agaacattat ggaggcccat
9421 gtaggaataa atggagaagc aaatctggat ttcttaaaca ttcctttaac aattcctgaa
9481 atgcgtctac cttacacaat aatcacaact cctccactga aagatttctc tctatgggaa
9541 aaaacaggct tgaaggaatt cttgaaaacg acaaagcaat catttgattt aagtgtaaaa
9601 gctcagtata agaaaaacaa acacaggcat tccatcacaa atcctttggc tgtgctttgt
9661 gagtttatca gtcagagcat caaatccttt gacaggcatt ttgaaaaaaa cagaaacaat
9721 gcattagatt ttgtcaccaa atcctataat gaaacaaaaa ttaagtttga taagtacaaa
9781 gctgaaaaat ctcacgacga gctccccagg acctttcaaa ttcctggata cactgttcca
9841 gttgtcaatg ttgaagtgtc tccattcacc atagagatgt cggcattcgg ctatgtgttc
9901 ccaaaagcag tcagcatgcc tagtttctcc atcctaggtt ctgacgtccg tgtgccttca
9961 tacacattaa tcctgccatc attagagctg ccagtccttc atgtccctag aaatctcaag
10021 ctttctcttc cagatttcaa ggaattgtgt accataagcc atatttttat tcctgccatg
10081 ggcaatatta cctatgattt ctcctttaaa tcaagtgtca tcacactgaa taccaatgct
10141 gaacttttta accagtcaga tattgttgct catctccttt cttcatcttc atctgtcatt
10201 gatgcactgc agtacaaatt agagggcacc acaagattga caagaaaaag gggattgaag
10261 ttagccacag ctctgtctct gagcaacaaa tttgtggagg gtagtcataa cagtactgtg
10321 agcttaacca cgaaaaatat ggaagtgtca gtggcaacaa ccacaaaagc ccaaattcca
10381 attttgagaa tgaatttcaa gcaagaactt aatggaaata ccaagtcaaa acctactgtc
10441 tcttcctcca tggaatttaa gtatgatttc aattcttcaa tgctgtactc taccgctaaa
10501 ggagcagttg accacaagct tagcttggaa agcctcacct cttacttttc cattgagtca
10561 tctaccaaag gagatgtcaa gggttcggtt ctttctcggg aatattcagg aactattgct
10621 agtgaggcca acacttactt gaattccaag agcacacggt cttcagtgaa gctgcagggc
10681 acttccaaaa ttgatgatat ctggaacctt gaagtaaaag aaaattttgc tggagaagcc
10741 acactccaac gcatatattc cctctgggag cacagtacga aaaaccactt acagctagag
10801 ggcctctttt tcaccaacgg agaacataca agcaaagcca ccctggaact ctctccatgg
10861 caaatgtcag ctcttgttca ggtccatgca agtcagccca gttccttcca tgatttccct
10921 gaccttggcc aggaagtggc cctgaatgct aacactaaga accagaagat cagatggaaa
10981 aatgaagtcc ggattcattc tgggtctttc cagagccagg tcgagctttc caatgaccaa
11041 gaaaaggcac accttgacat tgcaggatcc ttagaaggac acctaaggtt cctcaaaaat
11101 atcatcctac cagtctatga caagagctta tgggatttcc taaagctgga tgtaaccacc
11161 agcattggta ggagacagca tcttcgtgtt tcaactgcct ttgtgtacac caaaaacccc
11221 aatggctatt cattctccat ccctgtaaaa gttttggctg ataaattcat tattcctggg
11281 ctgaaactaa atgatctaaa ttcagttctt gtcatgccta cgttccatgt cccatttaca
11341 gatcttcagg ttccatcgtg caaacttgac ttcagagaaa tacaaatcta taagaagctg
11401 agaacttcat catttgccct caacctacca acactccccg aggtaaaatt ccctgaagtt
11461 gatgtgttaa caaaatattc tcaaccagaa gactccttga ttcccttttt tgagataacc
11521 gtgcctgaat ctcagttaac tgtgtcccag ttcacgcttc caaaaagtgt ttcagatggc
11581 attgctgctt tggatctaaa tgcagtagcc aacaagatcg cagactttga gttgcccacc
11641 atcatcgtgc ctgagcagac cattgagatt ccctccatta agttctctgt acctgctgga
11701 attgccattc cttcctttca agcactgact gcacgctttg aggtagactc tcccgtgtat
11761 aatgccactt ggagtgccag tttgaaaaac aaagcagatt atgttgaaac agtcctggat
11821 tccacatgca gctcaaccgt acagttccta gaatatgaac ttaatgtttt gggaacacac
11881 aaaatcgaag atggtacgtt agcctctaag actaaaggaa catttgcaca ccgtgacttc
11941 agtgcagaat atgaagaaga tggcaaatat gaaggacttc aggaatggga aggaaaagcg
12001 cacctcaata tcaaaagccc agcgttcacc gatctccatc tgcgctacca gaaagacaag
12061 aaaggcatct ccacctcagc agcctcccca gccgtaggca ccgtgggcat ggatatggat
12121 gaagatgacg acttttctaa atggaacttc tactacagcc ctcagtcctc tccagataaa
12181 aaactcacca tattcaaaac tgagttgagg gtccgggaat ctgatgagga aactcagatc
12241 aaagttaatt gggaagaaga ggcagcttct ggcttgctaa cctctctgaa agacaacgtg
12301 cccaaggcca caggggtcct ttatgattat gtcaacaagt accactggga acacacaggg
12361 ctcaccctga gagaagtgtc ttcaaagctg agaagaaatc tgcaggacca tgctgagtgg
12421 gtttatcaag gggccattag ggaaattgat gatatcgacg agaggttcca gaaaggagcc
12481 agtgggacca ctgggaccta ccaagagtgg aaggacaagg cccagaatct gtaccaggaa
12541 ctgttgactc aggaaggcca agccagtttc cagggactca aggataacgt gtttgatggc
12601 ttggtacgag ttactcaaga attccatatg aaagtcaagc atctgattga ctcactcatt
12661 gattttctga acttccccag attccagttt ccggggaaac ctgggatata cactagggag
12721 gaactttgca ctatgttcat aagggaggta gggacggtac tgtcccaggt atattcgaaa
12781 gtccataatg gttcagaaat actgttttcc tatttccaag acctagtgat tacacttcct
12841 ttcgagttaa ggaaacataa actaatagat gtaatctcga tgtataggga actgttgaaa
12901 gatttatcaa aagaagccca agaggtattt aaagccattc agtctctcaa gaccacagag
12961 gtgctacgta atcttcagga ccttttacaa ttcattttcc aactaataga agataacatt
13021 aaacagctga aagagatgaa atttacttat cttattaatt atatccaaga tgagatcaac
13081 acaatcttca atgattatat cccatatgtt tttaaattgt tgaaagaaaa cctatgcctt
13141 aatcttcata agttcaatga atttattcaa aacgagcttc aggaagcttc tcaagagtta
13201 cagcagatcc atcaatacat tatggccctt cgtgaagaat attttgatcc aagtatagtt
13261 ggctggacag tgaaatatta tgaacttgaa gaaaagatag tcagtctgat caagaacctg
13321 ttagttgctc ttaaggactt ccattctgaa tatattgtca gtgcctctaa ctttacttcc
13381 caactctcaa gtcaagttga gcaatttctg cacagaaata ttcaggaata tcttagcatc
13441 cttaccgatc cagatggaaa agggaaagag aagattgcag agctttctgc cactgctcag
13501 gaaataatta aaagccaggc cattgcgacg aagaaaataa tttctgatta ccaccagcag
13561 tttagatata aactgcaaga tttttcagac caactctctg attactatga aaaatttatt
13621 gctgaatcca aaagattgat tgacctgtcc attcaaaact accacacatt tctgatatac
13681 atcacggagt tactgaaaaa gctgcaatca accacagtca tgaaccccta catgaagctt
13741 gctccaggag aacttactat catcctctaa ttttttaaaa gaaatcttca tttattcttc
13801 ttttccaatt gaactttcac atagcacaga aaaaattcaa aatgcctata ttgatcaaac
13861 catacagtga gccagccttg cagtaggcag tagactataa gcagaagcac atatgaactg
13921 gacctgcacc aaagctggca ccagggctcg gaaggtctct gaactcagaa ggatggcatt
13981 ttttgcaagt taaagaaaat caggatctga gttattttgc taaacttggg ggaggaggaa
14041 caaataaatg gagtctttat tgtgtatcat
//