LOCUS HM369361 4266 bp mRNA linear HUM 09-AUG-2011
DEFINITION Homo sapiens ras responsive element binding protein 1 isoform delta
(RREB1) mRNA, complete cds, alternatively spliced.
ACCESSION HM369361
VERSION HM369361.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4266)
AUTHORS Nitz,M.D., Harding,M.A., Smith,S.C., Thomas,S. and Theodorescu,D.
TITLE RREB1 Transcription Factor Splice Variants in Urologic Cancer
JOURNAL Am. J. Pathol. 179 (1), 477-486 (2011)
PUBMED 21703425
REFERENCE 2 (bases 1 to 4266)
AUTHORS Nitz,M.D., Harding,M.A., Smith,S.C., Thomas,S. and Theodorescu,D.
TITLE Direct Submission
JOURNAL Submitted (30-MAY-2010) Molecular Physiology and Biological
Physics, University of Virginia, PO Box 800422, Charlottesville, VA
22908-0422, USA
FEATURES Location/Qualifiers
source 1..4266
/db_xref="H-InvDB:HIT000649706"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="UMUC3"
/PCR_primers="fwd_name: RREB1delta F, fwd_seq:
ggtctatataagcagagctcgt, rev_name: RREB1delta R, rev_seq:
tattaggacaaggctggtgggcac"
/PCR_primers="fwd_seq: agctgatgaagtctttcactg, rev_seq:
cgtcggcggccagcacgtagc"
/PCR_primers="fwd_seq: gaagatggcagcctcggctcc, rev_seq:
caggggctgtgctgggggttc"
/PCR_primers="fwd_seq: cgctgagcatggaggccaaga, rev_seq:
cgcagcaaggctgtgccactc"
/PCR_primers="fwd_seq: gcagcgccgcgttcgcggcca, rev_seq:
ggagctggcccaagggaaaac"
gene 1..4266
/gene="RREB1"
CDS 1..4266
/gene="RREB1"
/note="alternatively spliced; RREB1delta"
/codon_start=1
/product="ras responsive element binding protein 1 isoform
delta"
/protein_id="ADO14469.1"
/translation="MTSSSPAGLEGSDLSSINTMMSAVMSVGKVTENGGSPQGIKSPS
KPPGPNRIGRRNQETKEEKSSYNCPLCEKICTTQHQLTMHIRQHNTDTGGADHSCSIC
GKSLSSASSLDRHMLVHSGERPYKCTVCGQSFTTNGNMHRHMKIHEKDPNSATATAPP
SPLKRRRLSSKRKLSHDAESEREDPAPAKKMVEDRQSGDLEKKADEVFHCPVCFKEFV
CKYGLETHMETHSDNPLRCDICCVTFRTHRGLLRHNALVHKQLPRDAMGRPFIQNNPS
IPAGFHDLGFTDFSCRKFPRISQAWCETNLRRCISEQHRFVCDTCDKAFPMLCSLALH
KQTHVAADQGQEKPQATPLPGDALDQKGFLALLGLQHTKDVRPAPAEEPLPDDNQAIQ
LQTLKCQLPQDPGCTNLLSLSPFEAASLGGSLTVLPATKDSIKHLSLQPFQKGFIIQP
DSSIVVKPISGESAIELADIQQILKMAASAPPQISLPPFSKAPAAPLQAIFKHMPPLK
PKPLVTPRTVVATSTPPPLINAQQASPGCISPSLPPPPLKLLKGSVEAASNAHLLQSK
SGTQPHATTRLSLQQPRAELPGQPEMKTQLEQDSIIEALLPLSMEAKIKQEITEGELK
AFMTAPGGKKTPAMRKVLYPCRFCNQVFAFSGVLRAHVRSHLGISPYQCNICDYIAAD
KAALIRHLRTHSGERPYICKICHYPFTVKANCERHLRKKHLKATRKDIEKNIEYVSSS
AAELVDAFCAPDTVCRLCGEDLKHYRALRIHMRTHCGRGLGGVHKGRKPFECKECSAA
FAAKRNCIHHILKQHLHVPEQDIESYVLAADGLGPAEAPAAEASGRGEDSGCAALGDC
KPLTAFLEPQNGFLHRGPTQPPPPHVSIKLEPASSFAVDFNEPLDFSQKGLALVQVKQ
ENISFLSPSSLVPYDCSMEPIDLSIPKNFRKGDKDLATPSEAKKPEEEAGSSEQPSPC
PAPGPSLPVTLGPSGILESPMVPAPAATPEPPAQPLQGPVQLAVPIYSSALVSSPPLV
GSSALLSGTALLRPLRPKPPLLLPKPPVTEELPPLASIAQIISSVSSAPTLLKTKVAD
PGPASTGSNTTASDSLGGSVPKAATTATPAATTSPKESSEPPAPASSPEAASPTEQGP
AGTSKKRGRKRGMRSRPRANSGGVDLDSSGEFASIEKMLATTDTNKFSPFLQTAEDNT
QDEVAGAPADHHGPSDEEQGSPPEDKLLRAKRNSYTNCLQKITCPHCPRVFPWASSLQ
RHMLTHTGERPYKCQTCERTFTLKHSLVRHQRIHQKARHAKHHGKDSDKEERGEEDSE
NESTHSGNNAVSENEAELAPNASNHMAVTRSRKEGLASATKDCSHREEKVTAGWPSEP
GQGDLNPESPAALGQDLLEPRSKRPAHPILATADGASQLVGME"
BASE COUNT 950 a 1459 c 1177 g 680 t
ORIGIN
1 atgacgtcaa gttcgcccgc tggcttggaa ggttcagacc tatcttccat caacaccatg
61 atgtcggcgg tcatgagtgt agggaaggtc acagagaatg gcgggagccc ccaggggatc
121 aagtccccct cgaagcctcc aggaccaaat cggattggca gaaggaacca ggaaacgaaa
181 gaggagaagt cttcctataa ctgccccctg tgtgagaaga tttgcactac ccagcaccag
241 ctgaccatgc acattcgcca gcacaacaca gacactggag gagccgacca ctcatgcagc
301 atctgcggaa agtcactgag ctcggccagc tccctcgatc gccacatgct ggtgcactct
361 ggcgagaggc cttacaagtg cactgtgtgt ggccagtcat ttaccaccaa tgggaacatg
421 cacagacata tgaagatcca tgagaaggac cctaacagtg ccacagccac agcccctcca
481 tctcctctga aacgtaggcg attgtcctcc aagaggaaac tgagtcacga tgccgagtca
541 gagagagaag acccagcacc agctaaaaag atggtagaag acaggcagtc aggtgacttg
601 gagaagaaag ctgatgaagt ctttcactgc ccagtatgtt tcaaggagtt tgtttgcaag
661 tatggactgg agacccacat ggagacccat tcagataacc cactaagatg tgacatttgt
721 tgtgtcacct ttcgaacaca tcgaggactg ctgcgtcaca acgcgcttgt ccacaaacaa
781 cttcccaggg atgcaatggg cagacctttc atacagaaca acccttcaat tcctgctggc
841 ttccacgact taggattcac ggacttctcc tgtaggaagt ttcctcgcat ttctcaggcc
901 tggtgcgaaa caaacctgcg gaggtgcatc agcgagcaac accgttttgt ctgcgacacc
961 tgtgacaagg cgttccccat gctctgctca ctggctctgc acaagcagac ccatgtggcg
1021 gcagaccagg gtcaagaaaa gccgcaggcc acgcccctgc ctggtgacgc cctggaccag
1081 aagggcttcc tggccttgct tggcctgcag cacaccaaag acgtcaggcc tgcccccgcc
1141 gaggagcccc tgccggatga caaccaggca attcagctcc agacactcaa gtgtcagcta
1201 cctcaggacc ccggctgcac caacctgctg agcctgtcac ctttcgaagc tgcttcccta
1261 ggcggttctc tcacagttct ccccgcgacc aaggacagca taaagcacct gtccctgcag
1321 cccttccaga agggcttcat catccagcct gacagcagca ttgtggtcaa gcccatctct
1381 ggcgagtcgg ccatcgagct ggcagacatc cagcaaattc tgaagatggc agcctcggct
1441 ccccctcaga tcagtcttcc gcccttctcc aaggcccctg ccgccccact gcaggcgatc
1501 ttcaagcaca tgccccctct gaagccaaag cccctggtca caccacggac ggtggtggcc
1561 acctccacgc ccccgcctct catcaacgcc cagcaggctt ccccgggctg tatcagcccc
1621 agcctgccgc caccgcccct gaagctcctc aaaggctcag tggaggcggc ctccaacgcc
1681 cacctgctgc agtccaagtc cgggacccag ccccacgcga ccacgcggct ctccctgcag
1741 cagccgcggg cggagctgcc gggccagcct gagatgaaga cgcagctgga gcaggacagc
1801 atcatcgagg ccctgctgcc gctgagcatg gaggccaaga tcaagcagga gatcacagag
1861 ggggaactca aggccttcat gacagcgccc ggcggcaaga agacgcccgc catgcgcaag
1921 gtgctctacc cctgccgctt ctgcaaccag gtgtttgcct tctcgggggt cttgcgtgcc
1981 cacgtgcgct cccacctggg catctcgcca taccagtgca acatctgcga ctacatcgcc
2041 gccgacaagg ccgcgctcat ccgccacctg cgcacgcaca gtggggagcg gccctacatt
2101 tgcaagatct gccactaccc cttcactgtc aaagccaact gcgagcggca cctgcgcaag
2161 aagcacctca aggccacccg caaggatatc gagaagaaca tcgagtatgt gagtagcagc
2221 gcggccgagc tggtggacgc cttctgcgcc ccggacaccg tgtgccggct gtgcggcgag
2281 gacctcaagc actatcgtgc cctgcgcatc cacatgcgca cgcactgcgg ccgcggcctg
2341 ggcggggtcc acaagggccg caagcccttc gagtgcaagg agtgcagcgc cgcgttcgcg
2401 gccaagcgca actgcatcca ccacatcctc aagcagcacc tgcacgtgcc cgagcaggac
2461 atcgagagct acgtgctggc cgccgacggc ctgggccccg cagaggcgcc ggccgctgag
2521 gcgtcggggc gcggggagga cagtggctgc gctgcccttg gtgactgcaa gcccctcact
2581 gccttcctgg aaccccagaa cggctttctt cacaggggcc ccacccagcc tccacctccc
2641 catgtctcga tcaagttgga gcccgccagt agctttgcgg tggacttcaa tgagcccctg
2701 gacttctcgc agaagggcct ggccctggtc caagtgaagc aggaaaacat ctcctttctg
2761 agcccttctt ccctggtccc ctatgactgc tccatggagc ccatcgacct gtccatcccc
2821 aagaacttca ggaaagggga caaggatttg gccactccca gcgaagccaa gaagcctgag
2881 gaggaggcgg ggagcagcga gcagccctct ccctgcccag cacccggccc ttctcttcct
2941 gtaactttgg ggcccagcgg aatcctggaa agccccatgg tccctgctcc ggcggccacc
3001 ccggaacccc cagcacagcc cctgcagggc cctgttcagc tggcggtccc aatctactcc
3061 tcagccctgg tcagcagccc tccactcgtg ggcagctcag ccctcctgag tggcacagcc
3121 ttgctgcgtc cactgcggcc caagcccccg ctgcttttgc caaagccccc cgtgacagaa
3181 gagctgcccc cgctggcctc cattgcccag atcatctcat ctgtatcctc ggcccccacc
3241 ctgctgaaaa ccaaggtggc ggacccaggg cccgcaagca ctggcagtaa caccacggct
3301 tcagacagct taggaggttc tgtccccaaa gccgccacca ccgccacccc cgctgccacc
3361 accagcccaa aagagtctag tgagcctccc gctccagcca gcagcccaga ggctgcctct
3421 cccaccgagc agggcccagc gggcacgtcg aagaagaggg gccggaaaag ggggatgagg
3481 agccgacccc gcgccaacag cggcggggtg gacctggact ccagcgggga gtttgccagc
3541 atcgagaaga tgctggccac cacagacacc aacaagttca gtccgtttct gcagacagcg
3601 gaggacaaca ctcaggatga ggtggccgga gcccctgccg accaccatgg gcccagtgat
3661 gaagagcagg gcagtccccc agaagacaag ctgctgaggg ccaagcggaa ctcgtacacc
3721 aactgcctgc agaagatcac ctgtccccac tgtccccggg ttttcccttg ggccagctcc
3781 ctacagaggc acatgctcac acacactggg gaaaggccat acaaatgtca gacctgcgag
3841 cgaaccttca ccttgaagca cagcctggtt cgccaccagc ggatccacca gaaagccagg
3901 catgccaaac accacgggaa ggacagcgac aaggaagagc ggggtgagga ggacagcgag
3961 aatgagtcca cccacagcgg caacaacgcc gtctcagaga acgaggctga gctggctccc
4021 aatgccagca accacatggc tgtcacccgg agccggaagg agggcttggc cagtgccacc
4081 aaggactgca gccacaggga ggagaaggtc acggcagggt ggccgtctga gcctggccag
4141 ggtgacctta acccagagag cccggcggcc ctggggcagg acctgctgga gccgcgcagc
4201 aagaggcctg cccacccaat cctggccaca gctgatggcg cctcccagct cgtggggatg
4261 gagtga
//