LOCUS HM113488 2829 bp mRNA linear HUM 13-JUN-2010
DEFINITION Homo sapiens xeroderma pigmentosum complementation group C (XPC)
mRNA, complete cds.
ACCESSION HM113488
VERSION HM113488.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2829)
AUTHORS Chow,K.-C.
TITLE Elevated expression of xeroderma pigmentosum complementation group
C protein increases cisplatin resistance in lung adenocarcinoma
cells
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2829)
AUTHORS Chow,K.-C.
TITLE Direct Submission
JOURNAL Submitted (11-APR-2010) Graduate Institute of Biomedical Sciences,
National Chung Hsing University, 250 Kuo Kuang Road, Taichung,
Taiwan 40227, Taiwan, ROC
FEATURES Location/Qualifiers
source 1..2829
/db_xref="H-InvDB:HIT000649180"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p25"
/PCR_primers="fwd_seq: aaagaaagtggccaaggtga, rev_seq:
atattagcggccgctcacagcttctcaaatgg"
/PCR_primers="fwd_seq: agcaacagcaaagggaaaga, rev_seq:
gctggtctttggtttggtgt"
/PCR_primers="fwd_seq: gcgggtcgacaaatgaagaaagaagacttggag,
rev_seq: gggctctggtatggtctcaa"
gene 1..2829
/gene="XPC"
CDS 5..2827
/gene="XPC"
/note="nucleotide excision repair protein; RAD4; XP3;
XPCC"
/codon_start=1
/product="xeroderma pigmentosum complementation group C"
/protein_id="ADI50189.1"
/translation="MARKRAAGGEPRGRELRSQKSKAKSKARREEEEDDAFEDEKPPK
KSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDF
PSDLKKAHHLKRGATMNEDSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLLPV
KPVEIEIETPEQAKTRERSEMIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGF
YRNNICSQPDLHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQ
DNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKP
SKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKK
RSKPSSSEEDEGPGDKQEKATQRRPHGRERPVASRVSYKEESGSDEAGSGSDFELSSG
EASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSK
RGKKMCSDGEKAEKRSIAGIDQWLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPM
TYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETLRPYQSPFMDREKKEDLE
FQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRGEAVYSRDCVH
TLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEE
YQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLDIDCVQAITGFD
FHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLL
IRERLKRRYGPKSEAAAPHTDAGGGLSSDEEEGTSSQAEAARILAASWPQNREDEEKQ
KLKGGPKKTKREKKAAASHLFPFEQL"
BASE COUNT 803 a 675 c 829 g 522 t
ORIGIN
1 caacatggct cggaaacgcg cggccggcgg ggagccgcgg ggacgcgaac tgcgcagcca
61 gaaatccaag gccaagagca aggcccggcg tgaggaggag gaggacgatg cctttgaaga
121 tgagaaaccc ccaaagaaga gccttctctc caaagtttca caaggaaaga ggaaaagagg
181 ctgcagtcat cctgggggtt cagcagatgg tccagcaaaa aagaaagtgg ccaaggtgac
241 tgttaaatct gaaaacctca aggttataaa ggatgaagcc ctcagcgatg gggatgacct
301 cagggacttt ccaagtgacc tcaagaaggc acaccatctg aagagaggcg ctaccatgaa
361 tgaagacagc aatgaagaag aggaagaaag tgaaaatgat tgggaagagg ttgaagaact
421 tagtgagcct gtgctgggtg acgtgagaga aagtacagcc ttctctcgat ctcttctgcc
481 tgtgaagcca gtggagatag agattgaaac gccagagcag gcgaagacaa gagaaagaag
541 tgaaatgata aaactggagt ttgagacata tcttcggagg gcgatgaaac gtttcaataa
601 aggcgtccat gaggacacac acaaggttca ccttctctgc ctgctagcaa atggcttcta
661 tcgaaataac atctgcagcc agccagatct gcatgctatt ggcctgtcca tcatcccagc
721 ccgctttacc agagtgctgc ctcgagatgt ggacacctac tacctctcaa acctggtgaa
781 gtggttcatt ggaacattta cagttaatgc agaactttca gccagtgaac aagataacct
841 gcagactaca ttggaaagga gatttgctat ttactctgct cgagatgatg aggaattggt
901 ccatatattc ttactgattc tccgggctct gcagctcttg acccggctgg tattgtctct
961 acagccaatt cctctgaagt cagcaacagc aaagggaaag aaaccttcca aggaaagatt
1021 gactgcggat ccaggaggct cctcagaaac ttccagccaa gttctagaaa accacaccaa
1081 accaaagacc agcaaaggaa ccaaacaaga ggaaaccttt gctaagggca cctgcaggcc
1141 aagtgccaaa gggaagagga acaagggagg cagaaagaaa cggagcaagc cctcctccag
1201 cgaggaagat gagggcccag gagacaagca ggagaaggca acccagcgac gtccgcatgg
1261 ccgggagcgg ccggtggcct ccagggtgtc ttataaagag gagagtggga gtgatgaggc
1321 tggcagcggc tctgattttg agctctccag tggagaagcc tctgatccct ctgatgagga
1381 ttccgaacct ggccctccaa agcagaggaa agcccccgct cctcagagga caaaggctgg
1441 gtccaagagt gcctccagga cccatcgtgg gagccatcgt aaggacccaa gcttgccagc
1501 ggcatcctca agctcttcaa gcagtaaaag aggcaagaaa atgtgcagcg atggtgagaa
1561 ggcagaaaag agaagcatag ctggtataga ccagtggcta gaggtgttct gtgagcagga
1621 ggaaaagtgg gtatgtgtag actgtgtgca cggtgtggtg ggccagcctc tgacctgtta
1681 caagtacgcc accaagccca tgacctatgt ggtgggcatt gacagtgacg gctgggtccg
1741 agatgtcaca cagaggtacg acccagtctg gatgacagtg acccgcaagt gccgggttga
1801 tgctgagtgg tgggccgaga ccttgagacc ataccagagc ccatttatgg acagggagaa
1861 gaaagaagac ttggagtttc aggcaaaaca catggaccag cctttgccca ctgccattgg
1921 cttatataag aaccaccctc tgtatgccct gaagcggcat ctcctgaaat atgaggccat
1981 ctatcccgag acagctgcca tccttgggta ttgtcgtgga gaagcggtct actccaggga
2041 ttgtgtgcac actctgcatt ccagggacac gtggctgaag aaagcaagag tggtgaggct
2101 tggagaagta ccctacaaga tggtgaaagg cttttctaac cgtgctcgga aagcccgact
2161 tgctgagccc cagctgcggg aagaaaatga cctgggcctg tttggctact ggcagacaga
2221 ggagtatcag cccccagtgg ccgtggacgg gaaggtgccc cggaacgagt ttgggaatgt
2281 gtacctcttc ctgcccagca tgatgcctat tggctgtgtc cagctgaacc tgcccaatct
2341 acaccgcgtg gcccgcaagc tggacatcga ctgtgtccag gccatcactg gctttgattt
2401 ccatggcggc tactcccatc ccgtgactga tggatacatc gtctgcgagg aattcaaaga
2461 cgtgctcctg actgcctggg aaaatgagca ggcagtcatt gaaaggaagg agaaggagaa
2521 aaaggagaag cgggctctag ggaactggaa gttgctggcc aaaggtctgc tcatcaggga
2581 gaggctgaag cgtcgctacg ggcccaagag tgaggcagca gctccccaca cagatgcagg
2641 aggtggactc tcttctgatg aagaggaggg gaccagctct caagcagaag cggccaggat
2701 actggctgcc tcctggcctc aaaaccgaga agatgaagaa aagcagaagc tgaagggtgg
2761 gcccaagaag accaaaaggg aaaagaaagc agcagcttcc cacctgttcc catttgagca
2821 gctgtgagc
//