LOCUS HM068881 1606 bp mRNA linear HUM 03-SEP-2010
DEFINITION Homo sapiens neuregulin 3 variant 10 (NRG3) mRNA, complete cds,
alternatively spliced.
ACCESSION HM068881
VERSION HM068881.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1606)
AUTHORS Kao,W.T., Wang,Y., Kleinman,J.E., Lipska,B.K., Hyde,T.M.,
Weinberger,D.R. and Law,A.J.
TITLE Common genetic variation in Neuregulin 3 (NRG3) influences risk for
schizophrenia and impacts NRG3 expression in human brain
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 107 (35), 15619-15624 (2010)
PUBMED 20713722
REFERENCE 2 (bases 1 to 1606)
AUTHORS Kao,W.T.K. and Law,A.J.
TITLE Direct Submission
JOURNAL Submitted (08-APR-2010) Clinical Brain Disorders Branch, NIMH/NIH,
10 Center Drive, Building 10, Room 3C-105, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..1606
/db_xref="H-InvDB:HIT000649175"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q22"
/clone="WKCBDA51F"
/tissue_type="brain"
/dev_stage="adult"
gene 1..1606
/gene="NRG3"
CDS 1..231
/gene="NRG3"
/note="growth factor; alternatively spliced"
/codon_start=1
/product="neuregulin 3 variant 10"
/protein_id="ADK90028.1"
/translation="MECGIPPTLVCVGRGGGLHTVGVFHVLSQLISLCTIPEVFKEKP
KIRRHIPQSDPSTSNPAETRTLHTVSMMASAL"
BASE COUNT 488 a 373 c 379 g 366 t
ORIGIN
1 atggagtgtg gtatacctcc aacccttgta tgcgttggga gaggaggggg actacacacg
61 gtaggggtat ttcatgttct ttctcaattg atttccttgt gtaccattcc ggaggtcttt
121 aaagaaaagc ccaagatacg acgacatatt ccacagagcg atccgagcac ttcaaaccct
181 gccgagacaa ggaccttgca tactgtctca atgatggcga gtgctttgtg atcgaaaccc
241 tgaccggatc ccataaacac tgtcggtgca aagaaggcta ccaaggagtc cgttgtgatc
301 aatttctgcc gaaaactgat tccatcttat cggatccaaa gacggggttt caccgtgtta
361 accaggatgg tctcaatttc ctgacctcgt gatccgccta cctcggcctc ccaaagtgct
421 gggattacag accacttggg gattgaattc atggagagtg aagaagttta tcaaaggcag
481 gtgctgtcaa tttcatgtat catctttgga attgtcatcg tgggcatgtt ctgtgcagca
541 ttctacttca aaagcaaaag gaatattaca gcaaattctg tgtctgagga aagatggaag
601 gaaacaagct aaacaaatcc aagagcagct gaaagtgcca caaaatggta aaagctacag
661 tctcaaagca tccagcacaa tggcaaagtc agagaacttg gtgaagagcc atgtccagct
721 gcaaaattat tcaaaggtgg aaaggcatcc tgtgactgca ttggagaaaa tgatggagtc
781 aagttttgtc ggcccccagt cattccctga ggtcccttct cctgacagag gaagccagtc
841 tgtcaaacac cacaggagtc tatcctcttg ctgcagccca gggcaaagaa gtggcatgct
901 ccataggaat gccttcagaa ggacaccccc gtcaccccga agtaggctag gtggaattgt
961 gggaccagca tatcagcaac tcgaagaatc aaggatccca gaccaggata cgataccttg
1021 ccaagggata gaggtcagga agactatatc ccacctgcct atacagctgt ggtgtgttga
1081 aagacccctg gacttaaagt attcatccag tggtttaaaa acccaacgaa atacatcaat
1141 aaatatgcaa ctgccttcaa gagagacaaa cccctatttt aatagcttgg agcaaaagga
1201 cctggtgggc tattcatcca caagggccag ttctgtgccc atcatccctt cagtgggttt
1261 agaggaaacc tgcctgcaaa tgccagggat ttctgaagtc aaaagcatca aatggtgcaa
1321 aaactcctat tcagctgacg ttgtcaatgt gagtattcca gtcagcgatt gtcttatagc
1381 agaacaacaa gaagtgaaaa tattgctaga aactgtccag gagcagatcc gaattctgac
1441 tgatgccaga cggtcagaag actacgaact ggccagcgta gaaaccgagg acagtgcaag
1501 cgaaaacaca gcctttctcc ccctgagtcc cacagccaaa tcagaacgag aggcgcaatt
1561 tgtcttaaga aatgaaatac aaagagactc tgcattgacc aagtga
//