LOCUS HF584702 1913 bp mRNA linear HUM 12-APR-2013
DEFINITION Homo sapiens partial mRNA for splice variant RANK-e5a (TNFRSF11A
gene).
ACCESSION HF584702
VERSION HF584702.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1913)
AUTHORS Papanastasiou A.
JOURNAL Submitted (12-JAN-2013) to the INSDC. Medical School, University of
Patras, Rion, Panepistimioupolis, 26500, GREECE.
REFERENCE 2
AUTHORS Papanastasiou A.D., Sirinian H., Zarkadis I.K., Kalofonos H.P.
TITLE Alternative splicing generates a truncated isoform of human
TNFRSF11A (RANK) with an altered capacity to activate NF-kB
JOURNAL Unpublished.
FEATURES Location/Qualifiers
source 1..1913
/db_xref="H-InvDB:HIT000714965"
/organism="Homo sapiens"
/mol_type="mRNA"
/tissue_type="blood"
/db_xref="taxon:9606"
CDS 39..1847
/transl_table=1
/gene="TNFRSF11A"
/product="tumor necrosis factor receptor superfamily,
member 11a, NFKB activator"
/note="splice variant RANK-e5a"
/db_xref="GOA:Q9Y6Q6"
/db_xref="HGNC:HGNC:11908"
/db_xref="InterPro:IPR001368"
/db_xref="InterPro:IPR022323"
/db_xref="InterPro:IPR022361"
/db_xref="InterPro:IPR034040"
/db_xref="InterPro:IPR041648"
/db_xref="PDB:1LB5"
/db_xref="UniProtKB/Swiss-Prot:Q9Y6Q6"
/protein_id="CCQ44072.1"
/translation="MAPRARRRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLG
RCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVV
AGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPCYFSDAFSSTDKCRPWTN
CTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFG
VCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTL
EEKTFPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDE
YMDRPSQPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTE
PLCRTDWTPMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPPGEDCEPLVGSP
KRGPLPQCAYGMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPAS
GNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGAAAAAEPMGRPVQEETLARRDS
FAGNGPRFPDPCGGPEGLREPEKASRPVQEQGGAKA"
BASE COUNT 411 a 561 c 588 g 353 t
ORIGIN
1 ccgctgaggc cgcggcgccc gccagcctgt cccgcgccat ggccccgcgc gcccggcggc
61 gccgcccgct gttcgcgctg ctgctgctct gcgcgctgct cgcccggctg caggtggctt
121 tgcagatcgc tcctccatgt accagtgaga agcattatga gcatctggga cggtgctgta
181 acaaatgtga accaggaaag tacatgtctt ctaaatgcac tactacctct gacagtgtat
241 gtctgccctg tggcccggat gaatacttgg atagctggaa tgaagaagat aaatgcttgc
301 tgcataaagt ttgtgataca ggcaaggccc tggtggccgt ggtcgccggc aacagcacga
361 ccccccggcg ctgcgcgtgc acggctgggt accactggag ccaggactgc gagtgctgcc
421 gccgcaacac cgagtgcgcg ccgggcctgg gcgcccagca cccgtgctac ttctctgatg
481 ccttttcctc cacggacaaa tgcagaccct ggaccaactg taccttcctt ggaaagagag
541 tagaacatca tgggacagag aaatccgatg cggtttgcag ttcttctctg ccagctagaa
601 aaccaccaaa tgaaccccat gtttacttgc ccggtttaat aattctgctt ctcttcgcgt
661 ctgtggccct ggtggctgcc atcatctttg gcgtttgcta taggaaaaaa gggaaagcac
721 tcacagctaa tttgtggcac tggatcaatg aggcttgtgg ccgcctaagt ggagataagg
781 agtcctcagg tgacagttgt gtcagtacac acacggcaaa ctttggtcag cagggagcat
841 gtgaaggtgt cttactgctg actctggagg agaagacatt tccagaagat atgtgctacc
901 cagatcaagg tggtgtctgt cagggcacat gtgtaggagg tggtccctac gcacaaggcg
961 aagatgccag gatgctctca ttggtcagca agaccgagat agaggaagac agcttcagac
1021 agatgcccac agaagatgaa tacatggaca ggccctccca gcccacagac cagttactgt
1081 tcctcactga gcctggaagc aaatccacac ctcctttctc tgaacccctg gaggtggggg
1141 agaatgacag tttaagccag tgcttcacgg ggacacagag cacagtgggt tcagaaagct
1201 gcaactgcac tgagcccctg tgcaggactg attggactcc catgtcctct gaaaactact
1261 tgcaaaaaga ggtggacagt ggccattgcc cgcactgggc agccagcccc agccccaact
1321 gggcagatgt ctgcacaggc tgccggaacc ctcctgggga ggactgtgaa cccctcgtgg
1381 gttccccaaa acgtggaccc ttgccccagt gcgcctatgg catgggcctt ccccctgaag
1441 aagaagccag caggacggag gccagagacc agcccgagga tggggctgat gggaggctcc
1501 caagctcagc gagggcaggt gccgggtctg gaagctcccc tggtggccag tcccctgcat
1561 ctggaaatgt gactggaaac agtaactcca cgttcatctc cagcgggcag gtgatgaact
1621 tcaagggcga catcatcgtg gtctacgtca gccagacctc gcaggagggc gcggcggcgg
1681 ctgcggagcc catgggccgc ccggtgcagg aggagaccct ggcgcgccga gactccttcg
1741 cggggaacgg cccgcgcttc ccggacccgt gcggcggccc cgaggggctg cgggagccgg
1801 agaaggcctc gaggccggtg caggagcaag gcggggccaa ggcttgagcg ccccccatgg
1861 ctgggagccc gaagctcgga gccagggctc gcgagggcag caccgcagcc tct
//