LOCUS GQ231534 2954 bp mRNA linear HUM 11-JAN-2010
DEFINITION Homo sapiens neurogenic locus notch-like protein 2 (NOTCH2) mRNA,
complete cds.
ACCESSION GQ231534
VERSION GQ231534.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2954)
AUTHORS Arhancet,J.P. Jr. and Prokunina-Olsson,L.
TITLE Identification of Alternative Splicing Form of NOTCH2 Gene
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2954)
AUTHORS Arhancet,J.P. Jr. and Prokunina-Olsson,L.
TITLE Direct Submission
JOURNAL Submitted (01-JUN-2009) LTG/DCEG, NCI/NIH, 8717 Grovemont Circle,
Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..2954
/db_xref="H-InvDB:HIT000647763"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p11.2"
gene 1..2954
/gene="NOTCH2"
CDS 277..2868
/gene="NOTCH2"
/note="membrane bound receptor; lacks intracellular
domain; expressed from alternative promoter"
/codon_start=1
/product="neurogenic locus notch-like protein 2"
/protein_id="ADB12482.1"
/translation="MCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQA
MLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE
CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCL
NLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC
ERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTC
ANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLC
HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPCEHAG
KCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGV
HCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC
IDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICS
DQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGI
NRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQV
NECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGY
RCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGGSWRYQQGPE
GILDLALSVPESQCPGLWGCNAPPRAHSSVVLPAFTDWILSFEETLWPPKMQVVDSHL
PTLYFSI"
BASE COUNT 708 a 698 c 787 g 759 t
ORIGIN
1 tcaacaaaat gccaagtgga tcattttgac tctcacagca atccaactgg acatttgacc
61 atgccccgtg gtcagtggag agcttcttct ctgaaggcca cttttatcta gcacatcaag
121 gctatacacc tctttcacta agaagaattt ggcactttta tgttgtgaga gctgagattc
181 accattctcc accatcctga gaagagcttt gataganggg ctactcctga ggcattgcng
241 tgtcgagatg gctatgaacc ctgtgtaaat gaaggaatgt gtgttaccta ccacaatggc
301 acaggatact gcaaatgtcc agaaggcttc ttgggggaat attgtcaaca tcgagacccc
361 tgtgagaaga accgctgcca gaatggtggg acttgtgtgg cccaggccat gctggggaaa
421 gccacgtgcc gatgtgcctc agggtttaca ggagaggact gccagtactc aacatctcat
481 ccatgctttg tgtctcgacc ctgcctgaat ggcggcacat gccatatgct cagccgggat
541 acctatgagt gcacctgtca agtcgggttt acaggtaagg agtgccaatg gacggatgcc
601 tgcctgtctc atccctgtgc aaatggaagt acctgtacca ctgtggccaa ccagttctcc
661 tgcaaatgcc tcacaggctt cacagggcag aaatgtgaga ctgatgtcaa tgagtgtgac
721 attccaggac actgccagca tggtggcacc tgcctcaacc tgcctggttc ctaccagtgc
781 cagtgccctc agggcttcac aggccagtac tgtgacagcc tgtatgtgcc ctgtgcaccc
841 tcaccttgtg tcaatggagg cacctgtcgg cagactggtg acttcacttt tgagtgcaac
901 tgccttccag gttttgaagg gagcacctgt gagaggaata ttgatgactg ccctaaccac
961 aggtgtcaga atggaggggt ttgtgtggat ggggtcaaca cttacaactg ccgctgtccc
1021 ccacaatgga caggacagtt ctgcacagag gatgtggatg aatgcctgct gcagcccaat
1081 gcctgtcaaa atgggggcac ctgtgccaac cgcaatggag gctatggctg tgtatgtgtc
1141 aacggctgga gtggagatga ctgcagtgag aacattgatg attgtgcctt cgcctcctgt
1201 actccaggct ccacctgcat cgaccgtgtg gcctccttct cttgcatgtg cccagagggg
1261 aaggcaggtc tcctgtgtca tctggatgat gcatgcatca gcaatccttg ccacaagggg
1321 gcactgtgtg acaccaaccc cctaaatggg caatatattt gcacctgccc acaaggctac
1381 aaaggggctg actgcacaga agatgtggat gaatgtgcca tggccaatag caatccttgt
1441 gagcatgcag gaaaatgtgt gaacacggat ggcgccttcc actgtgagtg tctgaagggt
1501 tatgcaggac ctcgttgtga gatggacatc aatgagtgcc attcagaccc ctgccagaat
1561 gatgctacct gtctggataa gattggaggc ttcacatgtc tgtgcatgcc aggtttcaaa
1621 ggtgtgcatt gtgaattaga aataaatgaa tgtcagagca acccttgtgt gaacaatggg
1681 cagtgtgtgg ataaagtcaa tcgtttccag tgcctgtgtc ctcctggttt cactgggcca
1741 gtttgccaga ttgatattga tgactgttcc agtactccgt gtctgaatgg ggcaaagtgt
1801 atcgatcacc cgaatggcta tgaatgccag tgtgccacag gtttcactgg tgtgttgtgt
1861 gaggagaaca ttgacaactg tgaccccgat ccttgccacc atggtcagtg tcaggatggt
1921 attgattcct acacctgcat ctgcaatccc gggtacatgg gcgccatctg cagtgaccag
1981 attgatgaat gttacagcag cccttgcctg aacgatggtc gctgcattga cctggtcaat
2041 ggctaccagt gcaactgcca gccaggcacg tcaggggtta attgtgaaat taattttgat
2101 gactgtgcaa gtaacccttg tatccatgga atctgtatgg atggcattaa tcgctacagt
2161 tgtgtctgct caccaggatt cacagggcag agatgtaaca ttgacattga tgagtgtgcc
2221 tccaatccct gtcgcaaggg tgcaacatgt atcaacggtg tgaatggttt ccgctgtata
2281 tgccccgagg gaccccatca ccccagctgc tactcacagg tgaacgaatg cctgagcaat
2341 ccctgcatcc atggaaactg tactggaggt ctcagtggat ataagtgtct ctgtgatgca
2401 ggctgggttg gcatcaactg tgaagtggac aaaaatgaat gcctttcgaa tccatgccag
2461 aatggaggaa cttgtgacaa tctggtgaat ggatacaggt gtacttgcaa gaagggcttt
2521 aaaggctata actgccaggt gaatattgat gaatgtgcct caaatccatg cctgaaccaa
2581 ggaacctgct ttgatgacat aagtggctac acttgccact gtgtgctgcc atacacaggt
2641 gggtcctgga ggtaccagca gggaccagag gggatacttg accttgcttt gtcagtgcct
2701 gagtctcagt gcccaggtct gtggggctgt aatgctcctc cgagggctca ctcctcagtt
2761 gtccttcctg cctttactga ctggatcttg agctttgagg aaacattgtg gcctcctaag
2821 atgcaagtgg tggacagtca tttgcctaca ttgtacttta gtatttgaaa gaaatttttt
2881 tttaattgta tgtggctgga accaggcaca tagatgatgg ttgtctatca tttgaatgtt
2941 tccaggacat tagc
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