LOCUS FR748214 2056 bp mRNA linear HUM 18-JUL-2011
DEFINITION Homo sapiens mRNA for transcription factor 4 isoform C- (TCF4
gene).
ACCESSION FR748214
VERSION FR748214.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2056)
AUTHORS Sepp M.
JOURNAL Submitted (02-DEC-2010) to the INSDC. Sepp M., Department of Gene
Technolgy, Tallinn University of Technology, Akadeemia tee 15,
12618 Tallinn, ESTONIA.
REFERENCE 2
AUTHORS Sepp M., Kannike K., Eesmaa A., Urb M., Timmusk T.
TITLE functional diversity of human basic helix-loop-helix transcription
factor TCF4 isoforms generated by alternative 5' exon usage and
splicing
JOURNAL PLoS One 6(7), e22138-e22138(2011).
PUBMED 21789225
FEATURES Location/Qualifiers
source 1..2056
/db_xref="H-InvDB:HIT000714776"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 1..1932
/gene="TCF4"
/product="transcription factor 4, isoform C-"
/note="exons 4-20"
/db_xref="GOA:P15884"
/db_xref="HGNC:HGNC:11634"
/db_xref="InterPro:IPR011598"
/db_xref="InterPro:IPR036638"
/db_xref="PDB:2KWF"
/db_xref="PDB:6OD3"
/db_xref="PDB:6OD4"
/db_xref="PDB:6OD5"
/db_xref="UniProtKB/Swiss-Prot:P15884"
/protein_id="CBY80193.1"
/translation="MFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGNGGHPSPS
RNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSL
LGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHSSAMEVQTKKVRKVPPGLPSSV
YAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQDGHHSSDPWSSSSGMNQPGYAGML
GNSSHIPQSSSYCSLHPHERLSYPSHSSADINSSLPPMSTFHRSGTNHYSTSSCTPPA
NGTDSIMANRGSGAAGSSQTGDALGKALASIYSPDHTNNSFSSNPSTPVGSPPSLSAG
TAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLERLDDAIHVLRNHAVGPSTAMPGGHG
DMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLMVGTHREDGVALRGSHSLLPNQVPV
PQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSSGSSEIKSDDEGDENLQDTKSSEDK
KLDDDKKDIKSITSNNDDEDLTPEQKAEREKERRMANNARERLRVRDINEAFKELGRM
VQLHLKSDKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSSEPPPL
SLAGPHPGMGDASNHMGQM"
variation 1857
/replace="a"
/note="SNP rs8766"
BASE COUNT 555 a 566 c 484 g 451 t
ORIGIN
1 atgttttcac ctcctgtgag cagtgggaaa aatggaccaa cttctttggc aagtggacat
61 tttactggct caaatgtaga agacagaagt agctcagggt cctgggggaa tggaggacat
121 ccaagcccgt ccaggaacta tggagatggg actccctatg accacatgac cagcagggac
181 cttgggtcac atgacaatct ctctccacct tttgtcaatt ccagaataca aagtaaaaca
241 gaaaggggct catactcatc ttatgggaga gaatcaaact tacagggttg ccaccagcag
301 agtctccttg gaggtgacat ggatatgggc aacccaggaa ccctttcgcc caccaaacct
361 ggttcccagt actatcagta ttctagcaat aatccccgaa ggaggcctct tcacagtagt
421 gccatggagg tacagacaaa gaaagttcga aaagttcctc caggtttgcc atcttcagtc
481 tatgctccat cagcaagcac tgccgactac aatagggact cgccaggcta tccttcctcc
541 aaaccagcaa ccagcacttt ccctagctcc ttcttcatgc aagatggcca tcacagcagt
601 gacccttgga gctcctccag tgggatgaat cagcctggct atgcaggaat gttgggcaac
661 tcttctcata ttccacagtc cagcagctac tgtagcctgc atccacatga acgtttgagc
721 tatccatcac actcctcagc agacatcaat tccagtcttc ctccgatgtc cactttccat
781 cgtagtggta caaaccatta cagcacctct tcctgtacgc ctcctgccaa cgggacagac
841 agtataatgg caaatagagg aagcggggca gccggcagct cccagactgg agatgctctg
901 gggaaagcac ttgcttcgat ctattctcca gatcacacta acaacagctt ttcatcaaac
961 ccttcaactc ctgttggctc tcctccatct ctctcagcag gcacagctgt ttggtctaga
1021 aatggaggac aggcctcatc gtctcctaat tatgaaggac ccttacactc tttgcaaagc
1081 cgaattgaag atcgtttaga aagactggat gatgctattc atgttctccg gaaccatgca
1141 gtgggcccat ccacagctat gcctggtggt catggggaca tgcatggaat cattggacct
1201 tctcataatg gagccatggg tggtctgggc tcagggtatg gaaccggcct tctttcagcc
1261 aacagacatt cactcatggt ggggacccat cgtgaagatg gcgtggccct gagaggcagc
1321 cattctcttc tgccaaacca ggttccggtt ccacagcttc ctgtccagtc tgcgacttcc
1381 cctgacctga acccacccca ggacccttac agaggcatgc caccaggact acaggggcag
1441 agtgtctcct ctggcagctc tgagatcaaa tccgatgacg agggtgatga gaacctgcaa
1501 gacacgaaat cttcggagga caagaaatta gatgacgaca agaaggatat caaatcaatt
1561 actagcaata atgacgatga ggacctgaca ccagagcaga aggcagagcg tgagaaggag
1621 cggaggatgg ccaacaatgc ccgagagcgt ctgcgggtcc gtgacatcaa cgaggctttc
1681 aaagagctcg gccgcatggt gcagctccac ctcaagagtg acaagcccca gaccaagctc
1741 ctgatcctcc accaggcggt ggccgtcatc ctcagtctgg agcagcaagt ccgagaaagg
1801 aatctgaatc cgaaagctgc gtgtctgaaa agaagggagg aagagaaggt gtcctcggag
1861 cctccccctc tctccttggc cggcccacac cctggaatgg gagacgcatc gaatcacatg
1921 ggacagatgt aaaagggtcc aagttgccac attgcttcat taaaacaaga gaccacttcc
1981 ttaacagctg tattatctta aacccacata aacacttctc cttaaccccc atttttgtaa
2041 tataagacaa gtctga
//