LOCUS FR748211 2128 bp mRNA linear HUM 18-JUL-2011
DEFINITION Homo sapiens mRNA for transcription factor 4 isoform B- (TCF4
gene).
ACCESSION FR748211
VERSION FR748211.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2128)
AUTHORS Sepp M.
JOURNAL Submitted (02-DEC-2010) to the INSDC. Sepp M., Department of Gene
Technolgy, Tallinn University of Technology, Akadeemia tee 15,
12618 Tallinn, ESTONIA.
REFERENCE 2
AUTHORS Sepp M., Kannike K., Eesmaa A., Urb M., Timmusk T.
TITLE functional diversity of human basic helix-loop-helix transcription
factor TCF4 isoforms generated by alternative 5' exon usage and
splicing
JOURNAL PLoS One 6(7), e22138-e22138(2011).
PUBMED 21789225
FEATURES Location/Qualifiers
source 1..2128
/db_xref="H-InvDB:HIT000714773"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 1..2004
/gene="TCF4"
/product="transcription factor 4, isoform B-"
/note="exons 3-20"
/db_xref="GOA:P15884"
/db_xref="HGNC:HGNC:11634"
/db_xref="InterPro:IPR011598"
/db_xref="InterPro:IPR036638"
/db_xref="PDB:2KWF"
/db_xref="PDB:6OD3"
/db_xref="PDB:6OD4"
/db_xref="PDB:6OD5"
/db_xref="UniProtKB/Swiss-Prot:P15884"
/protein_id="CBY80190.1"
/translation="MHHQQRMAALGTDKELSDLLDFSAMFSPPVSSGKNGPTSLASGH
FTGSNVEDRSSSGSWGNGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQS
KTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRP
LHSSAMEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPATSTFPSSFFMQ
DGHHSSDPWSSSSGMNQPGYAGMLGNSSHIPQSSSYCSLHPHERLSYPSHSSADINSS
LPPMSTFHRSGTNHYSTSSCTPPANGTDSIMANRGSGAAGSSQTGDALGKALASIYSP
DHTNNSFSSNPSTPVGSPPSLSAGTAVWSRNGGQASSSPNYEGPLHSLQSRIEDRLER
LDDAIHVLRNHAVGPSTAMPGGHGDMHGIIGPSHNGAMGGLGSGYGTGLLSANRHSLM
VGTHREDGVALRGSHSLLPNQVPVPQLPVQSATSPDLNPPQDPYRGMPPGLQGQSVSS
GSSEIKSDDEGDENLQDTKSSEDKKLDDDKKDIKSITSNNDDEDLTPEQKAEREKERR
MANNARERLRVRDINEAFKELGRMVQLHLKSDKPQTKLLILHQAVAVILSLEQQVRER
NLNPKAACLKRREEEKVSSEPPPLSLAGPHPGMGDASNHMGQM"
variation 1849
/replace="a"
/note="SNP rs8766"
BASE COUNT 575 a 581 c 505 g 467 t
ORIGIN
1 atgcatcacc aacagcgaat ggctgcctta gggacggaca aagagctgag tgatttactg
61 gatttcagtg cgatgttttc acctcctgtg agcagtggga aaaatggacc aacttctttg
121 gcaagtggac attttactgg ctcaaatgta gaagacagaa gtagctcagg gtcctggggg
181 aatggaggac atccaagccc gtccaggaac tatggagatg ggactcccta tgaccacatg
241 accagcaggg accttgggtc acatgacaat ctctctccac cttttgtcaa ttccagaata
301 caaagtaaaa cagaaagggg ctcatactca tcttatggga gagaatcaaa cttacagggt
361 tgccaccagc agagtctcct tggaggtgac atggatatgg gcaacccagg aaccctttcg
421 cccaccaaac ctggttccca gtactatcag tattctagca ataatccccg aaggaggcct
481 cttcacagta gtgccatgga ggtacagaca aagaaagttc gaaaagttcc tccaggtttg
541 ccatcttcag tctatgctcc atcagcaagc actgccgact acaataggga ctcgccaggc
601 tatccttcct ccaaaccagc aaccagcact ttccctagct ccttcttcat gcaagatggc
661 catcacagca gtgacccttg gagctcctcc agtgggatga atcagcctgg ctatgcagga
721 atgttgggca actcttctca tattccacag tccagcagct actgtagcct gcatccacat
781 gaacgtttga gctatccatc acactcctca gcagacatca attccagtct tcctccgatg
841 tccactttcc atcgtagtgg tacaaaccat tacagcacct cttcctgtac gcctcctgcc
901 aacgggacag acagtataat ggcaaataga ggaagcgggg cagccggcag ctcccagact
961 ggagatgctc tggggaaagc acttgcttcg atctattctc cagatcacac taacaacagc
1021 ttttcatcaa acccttcaac tcctgttggc tctcctccat ctctctcagc aggcacagct
1081 gtttggtcta gaaatggagg acaggcctca tcgtctccta attatgaagg acccttacac
1141 tctttgcaaa gccgaattga agatcgttta gaaagactgg atgatgctat tcatgttctc
1201 cggaaccatg cagtgggccc atccacagct atgcctggtg gtcatgggga catgcatgga
1261 atcattggac cttctcataa tggagccatg ggtggtctgg gctcagggta tggaaccggc
1321 cttctttcag ccaacagaca ttcactcatg gtggggaccc atcgtgaaga tggcgtggcc
1381 ctgagaggca gccattctct tctgccaaac caggttccgg ttccacagct tcctgtccag
1441 tctgcgactt cccctgacct gaacccaccc caggaccctt acagaggcat gccaccagga
1501 ctacaggggc agagtgtctc ctctggcagc tctgagatca aatccgatga cgagggtgat
1561 gagaacctgc aagacacgaa atcttcggag gacaagaaat tagatgacga caagaaggat
1621 atcaaatcaa ttactagcaa taatgacgat gaggacctga caccagagca gaaggcagag
1681 cgtgagaagg agcggaggat ggccaacaat gcccgagagc gtctgcgggt ccgtgacatc
1741 aacgaggctt tcaaagagct cggccgcatg gtgcagctcc acctcaagag tgacaagccc
1801 cagaccaagc tcctgatcct ccaccaggcg gtggccgtca tcctcagtct ggagcagcaa
1861 gtccgagaaa ggaatctgaa tccgaaagct gcgtgtctga aaagaaggga ggaagagaag
1921 gtgtcctcgg agcctccccc tctctccttg gccggcccac accctggaat gggagacgca
1981 tcgaatcaca tgggacagat gtaaaagggt ccaagttgcc acattgcttc attaaaacaa
2041 gagaccactt ccttaacagc tgtattatct taaacccaca taaacacttc tccttaaccc
2101 ccatttttgt aatataagac aagtctga
//