LOCUS FJ808773 12217 bp mRNA linear HUM 16-JUL-2015
DEFINITION Homo sapiens truncated PRUNE2 (PRUNE2) mRNA, complete cds,
alternatively spliced.
ACCESSION FJ808773
VERSION FJ808773.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 12217)
AUTHORS Salameh,A., Lee,A.K., Cardo-Vila,M., Nunes,D.N., Efstathiou,E.,
Staquicini,F.I., Dobroff,A.S., Marchio,S., Navone,N.M., Hosoya,H.,
Lauer,R.C., Wen,S., Salmeron,C.C., Hoang,A., Newsham,I., Lima,L.A.,
Carraro,D.M., Oliviero,S., Kolonin,M.G., Sidman,R.L., Do,K.A.,
Troncoso,P., Logothetis,C.J., Brentani,R.R., Calin,G.A.,
Cavenee,W.K., Dias-Neto,E., Pasqualini,R. and Arap,W.
TITLE PRUNE2 is a human prostate cancer suppressor regulated by the
intronic long noncoding RNA PCA3
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 112 (27), 8403-8408 (2015)
PUBMED 26080435
REFERENCE 2 (bases 1 to 12217)
AUTHORS Lee,A.K., Dias-Neto,E., Pasqualini,R. and Arap,W.
TITLE PRUNE2 is a new gene that prevents cellular transformation and it
is regulated by the ncRNA PCA3 in prostate cancer
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 12217)
AUTHORS Lee,A.K., Dias-Neto,E., Pasqualini,R. and Arap,W.
TITLE Direct Submission
JOURNAL Submitted (05-MAR-2009) Genitourinary Medical Oncology, UT MD
Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
FEATURES Location/Qualifiers
source 1..12217
/db_xref="H-InvDB:HIT000714753"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q21.13"
gene 1..12217
/gene="PRUNE2"
CDS 410..8611
/gene="PRUNE2"
/note="alternatively spliced"
/codon_start=1
/product="truncated PRUNE2"
/protein_id="ACY78254.1"
/translation="MESEKISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGL
SIEQTMLKDLKELSDGEIKVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFS
SYLSEEQQPRRQIAVYSENMELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDP
SVTCDQVVLVVKEVINRRCPEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQ
PSSVNFIENPPDLNDSNQAQVDANVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVRE
GAGPHHTLLPGLDSYSPIPEGAVAEEHAWSGEHGEHFDLFNFDPAPMASGQSQQSSHS
ADYSPADDFFPNSDLSEGQLPAGPEGLDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEF
VQRQDSPRDNSERNLSLTDFVGDESPSPERLKNTGKRIPPTPMNSLVESSPSTEEPAS
LYTEDMTQKATDTGHMGPPQTHARCSSWWGGLEIDSKNIADAWSSSEQESVFQSPESW
KEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNEESLPFQNLP
IEKSPLPNTSPQGTNHLIEDFASLWHSGRSPTAMPEPWGNPTDDGEPAAVAPFPAWSA
FGKEDHDEALKNTWNLHPTSSKTPSVRDPNEWAMAKSGFAFSSSELLDNSPSEINNEA
APEIWGKKNNDSRDHIFAPGNPSSDLDHTWTNSKPPKEDQNGLVDPKTRGKVYEKVDS
WNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSP
TFAGDEKETEHKPFAKEEGFGSKDGNSTAEETDIPPQSLQQSSRNRISSGPGNLDMWA
SPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQLYNETN
RQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSD
GQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSAPSEHHTLN
EKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPD
APAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHGDGQS
ESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEICIKSGK
ISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNS
GETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSLDFGDVPIDS
DVHVSSTRSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSPELNDSSVA
LSSWGQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFEKSF
DRKTPTFLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEHDISAT
VQPEDARVISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTA
DPKSENIYDYLDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTETEMQITAVEKEKRS
SPETGTTGDVAWQISPKASFPKNEDNSQLEMLGFSADSTEWWKASPQEGRLIESPFER
ELSDSSGVLEINSSVHQNASPWGVPVQGDIEPVETHYTNPFSDNHQSPFLEGNGKNSH
EQLWNIQPRQPDPDADKFSQLVKLDQIKEKDSREQTFVSAAGDELTPETPTQEQCQDT
MLPVCDHPDAAFTHAEENSCVTSNVSTNEGQETNQWEQEKSYLGEMTNSSIATENFPA
VSSPTQLIMKPGSEWDGSTPSEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDAKKPF
SLKADGENPDILTHCEHDSNSQASDSPDICHDSEAKEETEKHLSACMGPEVESSELCL
TEPEIDEEPIYEPGREFVPSNAELDSENATVLPPIGYQADIKGSSQPTSHKGSPEPSE
INGDNSTGLQVSEKGASPDMAPILEPVDRRIPRIENVATSIFVTHQEPTPEGDGSWIS
DSFSPESQPGARALFDGDPHLSTENPALVPDALLASDTCLDISEAAFDHSFSDASGLN
TSTGTIDDMSKLTLSEGHPETPVDGDLGKQDICSSEASWGDFEYDVMGQNIDEDFLRE
PEHFLYGGDPPLEEDSLKQSLAPYTPPFDLSYLTEPAQSAETIEEAGSPEDESLGCRA
AEIVLSALPDRRSEGNQAETKNRLPGSQLAVLHIREDPESVYLPVGAGSNILSPSNVD
WEVETDNSDLPAGGDIGPPNGASKEIPELEEEKTIPTKEPEQIKSEYKEERCTEKNED
RHALHMDYILVNREENSHSKPETCEERESIAELELYVGSKETGLQGTQLASFPDTCQP
ASLNERKGLSAEKMSSKGDTRSSFESPAQDQSWMFLGHSEVGDPSLDARDSGPGWSGK
TVEPFSELGLGEGPQLQILEEMKPLESLALEEASGPVSQSQKSKSRGRAGPGAVTHDN
EWEMLSPQPVQKNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGVLSPS
AADMRPEPPNSLDLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDE
LDTPDEADSFEYTGHDPTANKDSGQESESIPEYTAEEEREDNRLRRTVVIGEQEQRID
MKVIEPYRRVISHGGDSGNLL"
BASE COUNT 3608 a 2728 c 2775 g 3106 t
ORIGIN
1 accccgctcg tcttccttgg gccgagattt tccactgcgc ccctccgagt acccgggttc
61 caaaccccta gccacgacat ggaagaattt ttgcaacgcg ccaaatctaa actgaatcga
121 agcaaacgct tggagaaggt ccatgtggtt attgggccta aatcgtgtga cttggattct
181 ctcatttcta ccttcacata tgcttacttt ctagacaagt gaagacaaaa ctttagaatc
241 agcagttgtc aaagtcatta atccggttga gcagagcgat gccaacgttg agttccgaga
301 gtcttcctct tctctcgtgc taaaggagat tctccaggag gctcctgagc tcatcaccga
361 gcaactggct catcgcctca gaggtagcat tcttttcaag tggatgacca tggaatcaga
421 gaagatctca gagaagcagg aggaaattct ttctatcctg gaagaaaaat ttcctaactt
481 gcctccaaga gaggacatca tcaacgtcct acaggagacc cagttcagtg ctcagggttt
541 aagtattgaa cagacaatgt tgaaagatct aaaggagctg tcagatggag aaataaaagt
601 ggccattagt actgtgagca tgaaccttga gaattgtcta tttcacagca atattaccag
661 tgacttgaaa gcatttacag acaagtttgg ttttgatgtc ctcatcctgt tctccagcta
721 tctgtcagag gagcagcagc cgagacgaca gattgctgtg tactcagaaa acatggagct
781 gtgcagtcag atttgctgtg agctggaaga gtgtcagaac ccttgcctag aactggagcc
841 ctttgactgt ggctgtgatg agatcctggt gtaccaacaa gaggaccctt cagtgacttg
901 tgatcaggtg gttctcgttg tcaaggaagt catcaacagg aggtgtccag agatggtctc
961 caatagccgg acatcctcaa cagaagccgt ggcaggcagt gcccccctct cccaggggtc
1021 ttctgggatt atggaattgt atggttctga catagagcca caacccagct ctgtgaattt
1081 catagagaac cctccagatc tcaatgattc taaccaggct caggtggatg ccaatgtaga
1141 ccttgttagc ccagacagcg gactggctac cattaggagc agccgctcat ccaaggagag
1201 ctctgttttc ctcagtgacg acagccccgt gagagaaggt gctgggcctc accacaccct
1261 tctcccaggg cttgactcct acagccccat ccctgaaggg gcggtagcgg aggaacatgc
1321 atggtctgga gaacacggtg agcacttcga cctcttcaat tttgacccag cacccatggc
1381 ttctgggcag tcccagcaat cttctcattc tgcagactac tccccagcag atgacttctt
1441 ccccaacagc gacctgtcag aaggacagct ccccgctggg cctgaaggac ttgatggcat
1501 gggaaccaac atgtctaatt attcatccag ttcacttttg tcaggggctg gcaaagatag
1561 ccttgtggaa catgatgagg agtttgtcca gagacaagac agtcccagag ataactctga
1621 aagaaatttg agcctgacag attttgtggg agatgaatcc ccttccccag aaaggctaaa
1681 aaatactgga aagaggatcc caccaacacc catgaatagt ttagtagaaa gctcgccatc
1741 cactgaagaa ccagcctcac tctataccga agatatgacc caaaaagcaa ctgacacagg
1801 tcacatgggg ccacctcaga cccatgcacg gtgcagcagc tggtggggtg gtttggaaat
1861 tgactccaaa aatattgcag atgcgtggag ttccagtgaa caggaatctg ttttccagag
1921 ccctgaatca tggaaagagc ataagccaag ctccattgat aggagagcct cagattctgt
1981 atttcaacca aagagcctcg aatttacaaa gtcaggtccc tgggagtctg aatttggtca
2041 gcctgaactg ggtagcaatg atattcaaga caaaaatgag gaaagcttgc cgttccagaa
2101 cctgcccata gagaagtcac ctttgccaaa tacatctccc caaggaacaa accacctgat
2161 agaagacttt gcttctttgt ggcattctgg tcgctctccc acagccatgc ccgagccctg
2221 gggaaatcct acagatgatg gtgaaccagc agctgtggcg ccattcccag cctggagtgc
2281 atttggtaaa gaagatcatg atgaagcttt aaaaaatacc tggaatttgc acccaacaag
2341 cagcaagaca ccttctgtta gggacccgaa tgagtgggcc atggcaaaaa gtgggtttgc
2401 cttttcttct tcagaactac tggacaattc acccagtgag ataaacaatg aagcagctcc
2461 agaaatctgg ggcaagaaaa acaatgactc cagggatcac atctttgcac ctggaaatcc
2521 cagttctgat ctggatcaca catggactaa ttctaagcca ccaaaagaag atcagaatgg
2581 tttagtggat cctaaaacta ggggcaaggt atatgaaaag gtagactcct ggaacctttt
2641 tgaggagaat atgaagaaag gagggtcaga tgtcctagtt ccttgggaag attccttctt
2701 atcttacaaa tgttctgatt acagtgcatc caacctagga gaagattcgg tgccttcccc
2761 cttagatacc aattattcca cctcagactc ttacacatca ccaacatttg ctggagacga
2821 aaaggaaact gaacacaagc catttgctaa agaggaaggt tttgggtcaa aagatggtaa
2881 ctccacggca gaggagactg acattcctcc tcagtcactg caacagtcat ctcgaaatcg
2941 aatcagttca ggtcctggga acctagacat gtgggcttca cctcatacag ataacagttc
3001 tgaaataaat accactcaca acctggatga aaatgaactc aagacagagc acacagatgg
3061 taagaatatc tccatggagg atgacgtcgg ggaaagcagc cagtccagtt acgacgaccc
3121 cagcatgatg caactgtaca atgaaacaaa ccgacaactc acacttttgc acagcagcac
3181 caactcccgg cagacggccc ctgacagtct cgacttgtgg aacagagtga ttttggagga
3241 tactcagtcc actgcaacga tctcagatat ggacaatgat ttggactggg atgactgcag
3301 tgggggtgcg gcaatcccca gtgatggtca aacagaagga tacatggctg aaggttccga
3361 gccggaaacc cgatttacag tgagacagct ggaaccctgg ggcttggagt atcaggaagc
3421 aaatcaggta gattgggagc tccctgcctc tgatgagcat accaaggaca gtgctcccag
3481 tgaacatcac acattgaatg agaaaagtgg gcagctaatt gcaaacagta tttgggattc
3541 tgtcatgaga gataaagaca tgtcatcatt catgttacca ggctcctcac atatcacaga
3601 ttcagagcaa agggaattgc ctcctgaaat ccccagccat tcagcaaatg ttaaagacac
3661 tcattcccca gatgcgccag cagcctctgg aaccagtgaa tcagaggcac ttatatctca
3721 tcttgacaag caggacacag agagggaaac cctgcaaagt gatgcagcat ccttggcgac
3781 taggcttgag aatccagggt attttccaca cccagatcca tggaaaggtc atggcgatgg
3841 acaaagtgaa agtgagaagg aagcccaggg agccactgac agggggcacc ttgatgaaga
3901 ggaggtgatc gcctctggtg tggagaatgc ctcagggatt tctgaaaaag ggcagagtga
3961 ccaggaactg tcttctctgg ttgcatctga acatcaggaa atctgcatta aatcaggcaa
4021 aatcagctct cttgctgtca ctttcagtcc tcaaaccgag gaaccagagg aagttttaga
4081 gtatgaggag gggtcttaca atctagactc ccgtgatgtg caaacaggga tgtccgcaga
4141 taacctgcag ccaaaagata cccatgaaaa acacctcatg agtcaaagaa attcaggtga
4201 aactactgag acttcagatg ggatgaattt cacaaaatat gtatctgtac ctgaaaagga
4261 tcttgagaaa actgaagaat gtaactttct agagccagag aacgtgggtg gagggccacc
4321 tcacagagtt ccccgaagtc ttgactttgg ggacgtccct atagacagtg atgtgcatgt
4381 cagcagcaca cgttctgaga taaccaaaaa tcttgacgtt aaggggtctg aaaatagcct
4441 tccaggagcc ggttcgtctg gaaattttga cagagatact atttctagtg agtatactca
4501 ttcaagtgca tcaagtcctg agttaaatga ctcttcagtt gcactgtcct cctggggcca
4561 gcaacccagt tctgggtatc aagaagaaaa ccaaggcaac tggagtgaac agaatcacca
4621 agaatctgaa ctaattacca ctgatggcca agtagaaata gttaccaaag tgaaggattt
4681 agagaaaaac agaataaatg agtttgaaaa gagctttgat cgcaaaactc ctacattttt
4741 agagatctgg aatgactcag ttgatggtga ttccttttcc tctttatcca gtcctgaaac
4801 aggcaaatat tctgaacatt cagggacaca tcaggaaagc aatctaattg ctagctacca
4861 ggagaaaaat gaacatgaca tttctgcaac tgtgcagcca gaggatgcca gggtcatttc
4921 aacaagctca ggttctgatg atgacagtgt cggtggtgaa gagtcaatag aggaagagat
4981 ccaggtggcc aactgccacg ttgctgagga tgaatccaga gcttgggatt cattgaatga
5041 atctaataag ttcttggtca cagctgatcc taagtctgaa aatatttatg actacctaga
5101 cagctcagag ccagcagaga atgagaataa gtcaaaccca ttctgtgaca atcaacaaag
5161 cagccctgat ccctggactt tctcaccatt aacggagact gaaatgcaga ttacagcagt
5221 ggagaaggag aagagatctt ctccagaaac agggacaaca ggagatgttg catggcaaat
5281 atctcccaaa gcttcgttcc caaagaacga agataattct caactggaaa tgctgggctt
5341 ctcagctgat agcactgagt ggtggaaggc ctcaccccag gaagggagac taattgaaag
5401 tccatttgaa agggagctgt ctgactccag tggtgtgttg gagataaatt cttcagtaca
5461 ccaaaatgcc agtccctggg gagtaccagt tcagggtgat attgagcccg tggaaacaca
5521 ctatactaat ccttttagtg acaaccatca gtcacccttt ctggaaggta atgggaagaa
5581 ctcccatgag caactctgga acattcaacc aaggcagcca gacccagatg ctgacaagtt
5641 cagccagctt gtaaaattag accaaattaa agaaaaggac tcaagagagc aaacctttgt
5701 gtctgctgct ggtgatgagc tgactcctga aacacctacc caagagcagt gtcaggacac
5761 catgctgcca gtctgtgatc atccggacgc agcctttact cacgcagagg aaaatagttg
5821 tgttacatct aatgtttcaa ctaatgaagg tcaagaaaca aatcagtggg aacaagaaaa
5881 atcataccta ggtgagatga caaattcaag cattgccaca gaaaattttc ctgctgtcag
5941 ttctcccacc caactgataa tgaagccagg ctctgaatgg gatggctcta ccccaagtga
6001 ggactcccga ggtacctttg tgccagatat tttacatggc aactttcaag agggtgggca
6061 gctggcctct gccgcgcctg acttgtggat agatgctaag aagcccttca gtttgaaagc
6121 agatggtgag aatcctgata tcctgacgca ctgcgaacat gacagcaatt ctcaggcttc
6181 cgacagccct gatatatgtc acgattctga agcaaaggaa gagactgaga agcacctcag
6241 tgcttgcatg ggacctgaag tggaatccag tgagctttgt ctcactgagc cagagataga
6301 tgaagaaccc atttatgagc ctggacggga gtttgtccca tccaatgcag aactcgattc
6361 tgaaaacgca actgtgctgc ctccaattgg ctatcaagca gacataaagg gctcctctca
6421 gcccacctct cataaaggtt cacctgaacc ttctgaaata aacggtgaca acagtacagg
6481 tttacaagta tcagaaaaag gagccagccc agatatggca ccaattttgg aaccagttga
6541 cagaagaatc ccaaggattg aaaatgtggc aactagcatt tttgtaactc accaagagcc
6601 aactccagaa ggtgacggtt cttggatatc agacagcttt tctcctgaaa gtcagcctgg
6661 tgcaagagct ttgtttgatg gtgatccaca tttatccaca gagaatcctg ccttggttcc
6721 tgatgctttg ctagcctcag acacttgtct ggatataagc gaagctgcct ttgaccacag
6781 tttcagcgat gcctcaggtc tcaacacatc cacgggaaca atagatgaca tgagtaaact
6841 gacattatcc gaaggccatc cggaaacgcc agttgatggg gacctaggga agcaagatat
6901 ctgctcatct gaagcctcgt ggggtgattt tgaatatgat gtaatgggcc agaatatcga
6961 tgaagatttc ctgagagagc ctgaacactt cctgtatggt ggtgaccctc ctttggagga
7021 agattctctg aagcagtcgc tggcaccgta cacacctccc tttgatttgt cttatctcac
7081 agaacctgcc cagagtgctg aaacaataga ggaagctggg tctccagagg atgaatctct
7141 gggatgcaga gcagcagaga tagtgctttc tgcacttcct gatcgaagaa gtgagggaaa
7201 ccaggctgag accaaaaaca gactgcctgg atcccagctg gctgtgctgc atattcgtga
7261 agaccctgag tccgtttatt tgccggtagg agcaggctcc aacattttgt ctccatcaaa
7321 cgttgactgg gaagtagaaa cagataattc tgatttacca gcaggtggag acataggacc
7381 accaaatggt gccagcaagg aaataccaga attggaagaa gaaaaaacaa ttcctaccaa
7441 agagcctgag cagataaaat cagaatacaa ggaagaaaga tgtacagaga agaatgaaga
7501 tcgtcatgca ctacacatgg attacatact tgtaaaccgt gaagaaaatt cacactcaaa
7561 gccagagacc tgtgaagaaa gagaaagcat agctgaatta gaattgtatg taggctccaa
7621 agaaacaggg ctgcagggaa ctcagttagc aagcttccca gacacatgtc agccagcctc
7681 cttaaatgaa agaaaaggtc tctctgcaga gaaaatgtct tctaaaggcg atacgagatc
7741 atcttttgaa agccctgcac aagaccagag ttggatgttc ttgggccata gtgaggttgg
7801 tgatccatca ctggatgcca gggactcagg gcctgggtgg tctggcaaga ctgtggagcc
7861 gttctctgaa ctcggcttgg gtgagggtcc ccagctgcag attctggaag aaatgaagcc
7921 tctagaatct ttagcactag aggaagcctc tggtccagtc agccaatcac agaagagtaa
7981 gagccgaggc agggctggcc cgggtgcagt tacccatgac aatgaatggg aaatgctttc
8041 accacagcct gttcagaaaa acatgatccc tgacacggaa atggaggagg agacagagtt
8101 ccttgagctc ggaaccagga tatcaagacc aaatggacta ctgtcagagg atgtaggaat
8161 ggacatcccc tttgaagagg gcgtgctgag tcccagtgct gcagacatga ggcctgaacc
8221 tcctaattct ctggatctta atgacactca tcctcggaga atcaagctca cagccccaaa
8281 tatcaatctt tctctggacc aaagtgaagg atctattctc tctgatgata acttggacag
8341 tccagatgaa attgacatca atgtggatga acttgatacc cccgatgaag cagattcttt
8401 tgagtacact ggccatgatc ccacagccaa caaagattct ggccaagagt cagagtctat
8461 tccagaatat acggccgaag aggaacggga ggacaaccgg cttcggagga cagtggtcat
8521 tggagaacaa gagcagcgca ttgacatgaa ggtcatcgag ccctacagga gagtcatttc
8581 tcacggagga gattcaggta accttctctg aagtcttgct ggacaaatga ccctggaaag
8641 aatgaggaga agagttgctg gctggtgtgt gtgtgtgtat gttttggttg cgactgtgac
8701 atctttcctt ctgtctccat tccattgctg gccagcaaac ttgtgttaca tccctttcat
8761 gcctgtctgt gtcactcaga tatgtaataa gtactttaga gttgatggta gctgaagact
8821 atatgattgt gtacttgaat ggtgcaaccc caagaaggag gatgccaggg ctaggctgga
8881 tgaagaaatg ctaccagatg attgacagac ggttgaggaa gaatttgaaa tcattcatca
8941 ttgttcatcc atcttggttc atcagaacaa tccttgctgt gacacgacct tttataagtt
9001 caaaattcag cagtaaaatt aaatatgtca atagcttatc agaactcagt gggctgatcc
9061 caatggattg catccacatt ccagagagca tcatcaatat tgacttgaag ctgaaagaaa
9121 agccttagtt ggccatgctg gaagaagagg atgcttttct ggttcatggt tctgttgaaa
9181 catatctacc tgaaagagac agggctgatg ttaccttttt ccactttgca ctacctggtg
9241 ccattctaaa tttctaaggg gaaaaataga aagtttgttt actcttaaga tattttatga
9301 aattgtgtgt actttcctat tttgccaatt atgtgcctca aagattttag ttgagcctta
9361 gcaagaaagt aggaccttcc atttcaatac ttcattaaca cggtgtagtg atactttgtc
9421 ccttagactg gtgtttacca gtaagatacc tttaatccac tgttaagtat gagtggattt
9481 gtttccatag attagctgga tttccttttg gtgattgcat taggtttaaa gtacacaggt
9541 ctcaactctc cccaggaaag tttcccctgt ttgactccac ctttaaaatc ctaagcctga
9601 ctaggacagc cacaaaccac acaaggtgta aaaccatcat cagctaagtg cccgttttgt
9661 tcttgtttac cagaatctcc tttaacttct caaagggaag ccgggctttc taatccacgt
9721 caactttatt ttagttgtca aattgggcat tatattttat gtaaattggt cttttaacat
9781 cattttcctg atgaatgttg gtgaccacca cattgtgaaa tttaagaatc cgtgttgcat
9841 gtttggtagc tctctgagtt tcaggccata aactcagctc cagaggttac cttttaagtg
9901 ccaagaactc aagtgcaagg tggcctactc aaaaatcatt tggtagcatt cagttattca
9961 tgaattcctc tctcgcatgc attataaaaa gtgatctgct ttaaaacacc gtaatctgat
10021 cataggctta aaattaaata tgagtattac tttcatgtac aaaatatttc ctttatagtc
10081 ttcatatgcc ctttaaaatg ccaacaagat ttcaagtctg taggcctcta gtgaggtggg
10141 gtggcaaacc acagctaagt ctcgctcacc actgcaagct aagaatggtt tttacatttt
10201 gggttggaaa aatttttttt gaatatttca tgacacatga aaattattca aatgttagtg
10261 ccgataaata aagtggtact gaaacacagc cacacaaact tgtttttgta ctgtctacag
10321 ctactttcac actacagccg cagagctgag cagttcagca gaccgtatgt cccacaatgc
10381 ctaaaacatt gactatgttt acagaaaaag tttgctgacc cctgctctag caaacgcatc
10441 ctttcctact ccaccccaat ttgtatttag atagtttctc taacagaacg gacaaatgag
10501 gctgcaaact aatttatttt tgtcaaaaat caatgttttg acatccacag acagtgaaat
10561 aaaagaaatg gcttgctgaa aaacatgagg agtcctagcc acaaaatcac tgcttaggtt
10621 gcaattgcca aaatgaagcc ttcttagaag cacttcttta gtatatacag gtgttggctg
10681 aagtccgtgc ctcactctgg gaaccattct tagtctccag tgtctcctat tacaaagaag
10741 ctggcagaaa taaaaatgaa ggggtgagag cggttccacc ctagtctcat ggtggaaaat
10801 tcattgggga gagctgtcca ggatatttgg agtcctgggt agaaggagct tgtaactact
10861 ttaaagtcga catctttgca caggtgattg agtttctctg acctcattgc ttcacctctg
10921 tctcctcccg tccttccgca cgtgcccaca cacacgcagt tcagccctct ttcctccata
10981 agcctccatc gttttctctt ttctcttctt gatcctttca agcgagtatc ttgttgaatt
11041 gtatgttctg ttggatctcc tccttcataa catctggctt gttggacaga aaaaccctac
11101 agcccacccc ctcccacagc ccacctccac ttttgaaagc ccaaattaca cctctcccag
11161 aacacagtgt tgacgtaaat acagttaccc aatattcctg tttgttcacc tatttgctac
11221 tttcactcag tagcatccca ttttgtaaaa tgaattccat ggtcaccctg tcacaggaag
11281 taatgaaaaa tccagtgttc agtgtagtgg tgcaaacctg agggcataga gctgttcata
11341 gagggctctt gttatagcca aacagacaca gcaacaatct caccatttat atatatattt
11401 ttaacttgtc cagctcatct atggaaaact actcaggtgg tatgctgttt gaagcctcat
11461 cttcctacat gaaaattatg ggcatttgtc ccaatgattt tgtttcagct gttctgtagg
11521 ctgcataacc actctgatat ttaggtatct gctattttat tatcttaaaa gacaaattaa
11581 tttaattgca tgtgctaggg aaaagctacc atgtacattc accccaagta aatagaatcc
11641 tagatgaatc ctagaaaaat aatccctaag cagataggta gacagaggta aacattcaca
11701 tgatttagct ctctagctct tgcactctga acattcttgc tttgggtctg acttctggga
11761 actgctttgc atttctccta tagatctgta gttaagggaa ccaaggggtc attggggcaa
11821 aagcattgtt tctcaaagct ccttgattaa gagaaagaac agaaatttgc acagaagata
11881 gtgtcaagga gtgagaaagt ttgtttgagg gcagtagctc agtgtggaag aaaatcctga
11941 agtttctgtt gaagccatac aatgttctat ggggttactc tctaagacat tctctgaggt
12001 gtgtgaggaa gtcactactc ctagcctttg ttaagatgta attttaaata ttcagttatg
12061 gtactatgtt tgcaactctc gtcttatcac aatgcctcag tagtttgttc ccttagaaac
12121 atttagatgt gcacaaatta atcttttata tatctaaagg tttttctatc atgcattgga
12181 ttgctcagaa taaagtgtct gttagacttc gttttgg
//