LOCUS FJ588507 2230 bp mRNA linear HUM 31-DEC-2011
DEFINITION Homo sapiens metabotropic glutamate receptor 5 variant H (GRM5)
mRNA, complete cds, alternatively spliced.
ACCESSION FJ588507
VERSION FJ588507.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2230)
AUTHORS Cheng,H. and Feng,Y.-H.
TITLE A naturally occurring splicing variant of mGluR5
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2230)
AUTHORS Cheng,H. and Feng,Y.-H.
TITLE Direct Submission
JOURNAL Submitted (19-DEC-2008) Pharmacology, Uniformed Services University
of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814,
USA
FEATURES Location/Qualifiers
source 1..2230
/db_xref="H-InvDB:HIT000714747"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/note="PCR_primers=fwd_name: mGluR5+, rev_name: mGluR5-"
gene 1..2230
/gene="GRM5"
CDS 1..2184
/gene="GRM5"
/note="mGluR5h; alternatively spliced"
/codon_start=1
/product="metabotropic glutamate receptor 5 variant H"
/protein_id="ACU31024.1"
/translation="MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVH
HQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHS
AVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQN
LLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVH
TEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVAC
FCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDV
KWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKTHHV
QDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNFTGVS
GDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVWSKKSNIIR
SVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCD
LIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAG
ICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICT
KKPRPGGAGGSHPAVPLQRLGGLGEHNPQLASVRVGPLYPVVSQI"
BASE COUNT 573 a 520 c 580 g 557 t
ORIGIN
1 atggtccttc tgttgatcct gtcagtctta cttttgaaag aagatgtccg tgggagtgca
61 cagtccagtg agaggagggt ggtggctcac atgccgggtg acatcattat tggagctctc
121 ttttctgttc atcaccagcc tactgtggac aaagttcatg agaggaagtg tggggcggtc
181 cgtgaacagt atggcattca gagagtggag gccatgctgc ataccctgga aaggatcaat
241 tcagacccca cactcttgcc caacatcaca ctgggctgtg agataaggga ctcctgctgg
301 cattcggctg tggccctaga gcagagcatt gagttcataa gagattccct catttcttca
361 gaagaggaag aaggcttggt acgctgtgtg gatggctcct cctcttcctt ccgctccaag
421 aagcccatag taggggtcat tgggcctggc tccagttctg tagccattca ggtccagaat
481 ttgctccagc ttttcaacat acctcagatt gcttactcag caaccagcat ggatctgagt
541 gacaagactc tgttcaaata tttcatgagg gttgtgcctt cagatgctca gcaggcaagg
601 gccatggtgg acatagtgaa gaggtacaac tggacctatg tatcagccgt gcacacagaa
661 ggcaactatg gagaaagtgg gatggaagcc ttcaaagata tgtcagcgaa ggaagggatt
721 tgcatcgccc actcttacaa aatctacagt aatgcagggg agcagagctt tgataagctg
781 ctgaagaagc tcacaagtca cttgcccaag gcccgggtgg tggcctgctt ctgtgagggc
841 atgacggtga gaggtctgct gatggccatg aggcgcctgg gtctagcggg agaatttctg
901 cttctgggca gtgatggctg ggctgacagg tatgatgtga cagatggata tcagcgagaa
961 gctgttggtg gcatcacaat caagctccaa tctcccgatg tcaagtggtt tgatgattat
1021 tatctgaagc tccggccaga aacaaaccac cgaaaccctt ggtttcaaga attttggcag
1081 catcgttttc agtgccgact ggaagggttt ccacaggaga acagcaaata caacaagact
1141 tgcaatagtt ctctgactct gaaaacacat catgttcagg attccaaaat gggatttgtg
1201 atcaacgcca tctattcgat ggcctatggg ctccacaaca tgcagatgtc cctctgccca
1261 ggctatgcag gactctgtga tgccatgaag ccaattgatg gacggaaact tttggagtcc
1321 ctgatgaaaa ccaattttac tggggtttct ggagatacga tcctattcga tgagaatgga
1381 gactctccag gaaggtatga aataatgaat ttcaaggaaa tgggaaaaga ttactttgat
1441 tatatcaacg ttggaagttg ggacaatgga gaattaaaaa tggatgatga tgaagtatgg
1501 tccaagaaaa gcaacatcat cagatctgtg tgcagtgaac catgtgagaa aggccagatc
1561 aaggtgatcc gaaagggaga agtcagctgt tgttggacct gtacaccttg taaggagaat
1621 gagtatgtct ttgatgagta cacatgcaag gcatgccaac tggggtcttg gcccactgat
1681 gatctcacag gttgtgactt gatcccagta cagtatcttc gatggggtga ccctgaaccc
1741 attgcagctg tggtgtttgc ctgccttggc ctcctggcca ccctgtttgt tactgtagtc
1801 ttcatcattt accgtgatac accagtagtc aagtcctcaa gcagggaact ctgctacatt
1861 atccttgctg gcatctgcct gggctactta tgtaccttct gcctcattgc gaagcccaaa
1921 cagatttact gctaccttca gagaattggc attggtctct ccccagccat gagctactca
1981 gcccttgtaa caaagaccaa ccgtattgca aggatcctgg ctggcagcaa gaagaagatc
2041 tgtaccaaaa agcccagacc tggaggagct ggtggctctc accccgccgt cccccttcag
2101 agactcggtg gactcgggga gcacaacccc caactcgcca gtgtccgagt cggccctctg
2161 tatcccgtcg tctcccaaat atgacactct tatcataaga gattacactc agagctcctc
2221 gtcgttgtga
//