LOCUS FJ542286 3177 bp mRNA linear HUM 22-DEC-2008
DEFINITION Homo sapiens Abl2 isoform 1BSCTS mRNA, complete cds, alternatively
spliced.
ACCESSION FJ542286
VERSION FJ542286.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3177)
AUTHORS Perego,R.A., Corizzato,M., Bianchi,C., Eroini,B. and Bosari,S.
TITLE N- and C-terminal isoforms of Arg quantified by real-time PCR are
specifically expressed in human normal and neoplastic cells, in
neoplastic cell lines, and in HL-60 cell differentiation
JOURNAL Mol. Carcinog. 42 (4), 229-239 (2005)
PUBMED 15765532
REFERENCE 2 (bases 1 to 3177)
AUTHORS Bianchi,C., Torsello,B., Angeloni,V., Bombelli,S., Soldi,M.,
Invernizzi,L., Brambilla,P. and Perego,R.A.
TITLE Eight full-length abelson related gene (Arg) isoforms are
constitutively expressed in caki-1 cell line and cell distribution
of two isoforms has been analyzed after transfection
JOURNAL J. Cell. Biochem. 105 (5), 1219-1227 (2008)
PUBMED 18810762
REFERENCE 3 (bases 1 to 3177)
AUTHORS Perego,R., Bianchi,C., Torsello,B., Angeloni,V., Brambilla,P.,
Bombelli,S. and Invernizzi,L.
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2008) Experimental Medicine, Milano-Bicocca
University, Via Cadore, 48, Monza, MI 20052, Italy
FEATURES Location/Qualifiers
source 1..3177
/db_xref="H-InvDB:HIT000558722"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q24-q25"
/cell_line="renal clear cell carcinoma Caki-1"
CDS 1..3177
/note="lacks the second exon (63 bp) and 309 bp in the 3'
end that involves the internal actin binding domain;
alternatively spliced; Arg isoform 1BSCTS"
/codon_start=1
/product="Abl2 isoform 1BSCTS"
/protein_id="ACK76604.1"
/translation="MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTET
GFNIFTQHEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGD
NTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRS
AAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFS
TLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGG
QYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEP
PFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAAR
NCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAF
GVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADR
PSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVE
NKENIEGAQDATENSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFT
RDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYELTGLPEQDRMAMTLPRNCQ
RSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPLRT
PSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPV
LPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKP
KCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGR
PVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLL
SSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSS
AAAGVPGTNPVLNNLLSCVQEISDVVQR"
BASE COUNT 871 a 823 c 828 g 655 t
ORIGIN
1 atggggcagc aggtgggccg cgtcggggaa gctccggggc tccagcagcc tcagccccgc
61 gggatccggg gcagcagtgc agccaggccc tccggccgca ggcgggaccc ggcggggcgc
121 accacagaga ccggcttcaa tatcttcacc cagcatgaag ctttgcatcg tccctatggt
181 tgtgatgttg aaccccaggc actaaatgag gctatcaggt ggagctccaa ggagaacttg
241 ctcggagcca ctgagagtga ccctaatctc ttcgttgcac tttatgattt tgtagcaagt
301 ggtgataaca cactcagcat cactaaaggt gaaaagctac gagtccttgg ttacaaccag
361 aatggtgagt ggagtgaagt tcgctctaag aatgggcagg gctgggtgcc aagcaactac
421 atcaccccag tgaacagcct ggaaaaacac tcctggtacc atggacctgt gtcacgcagt
481 gcagctgagt atctgctcag cagtctaatc aatggcagct tcctggtgcg agaaagtgag
541 agtagccctg ggcagctgtc catctcgctc aggtacgagg gacgtgtgta tcactacagg
601 atcaatacca ctgcagatgg caaggtgtat gtgactgctg agagccgctt cagcaccttg
661 gcagagcttg tacaccatca ctccacagtg gctgatgggc tggtgacaac attacactac
721 ccagcaccca agtgtaataa gcctacagtc tatggtgtgt cccccatcca cgacaaatgg
781 gaaatggagc gaacagatat taccatgaag cacaaacttg ggggcggtca gtatggagag
841 gtttacgttg gcgtctggaa gaaatacagc cttacagttg ctgtgaaaac attgaaggaa
901 gataccatgg aggtagaaga attcctgaaa gaagctgcag taatgaagga aatcaagcat
961 cctaatctgg tacaactttt aggtgtgtgt actttggagc caccatttta cattgtgact
1021 gaatacatgc catacgggaa tttgctggat tacctccgag aatgcaaccg agaagaggtg
1081 actgcagttg tgctgctcta catggccact cagatttctt ctgcaatgga gtacttagag
1141 aagaagaatt tcatccatag agatcttgca gctcgtaact gcctagtggg agaaaaccat
1201 gtggtaaaag tggctgactt tggcttaagt agattgatga ctggagacac ttatactgct
1261 catgctggag ccaaatttcc tattaagtgg acagcaccag agagtcttgc ctacaatacc
1321 ttctcaatta aatctgacgt ctgggctttt ggggtattgt tgtgggaaat tgctacctat
1381 ggaatgtcac catatccagg tattgacctg tctcaggtct atgacctact agaaaaagga
1441 tatcgaatgg aacagcctga gggatgcccc cctaaggttt atgaacttat gagagcatgc
1501 tggaagtgga gccctgccga taggccctct tttgctgaaa cacaccaagc ttttgaaacc
1561 atgttccatg actccagcat ttctgaagag gtagctgagg agcttgggag agccgcctcc
1621 tcgtcatctg ttgttccata cctgccccgg ctacctatac ttccttccaa gactcggaca
1681 ctgaagaaac aggtggagaa caaggagaac attgaagggg cacaagatgc cacagaaaat
1741 tctgcttcca gtttagcacc agggttcatc agaggtgcac aggcctctag tggatcccca
1801 gcactgcctc gaaagcaaag agacaagtca cccagcagcc tcttggaaga tgccaaagag
1861 acatgcttca ccagggatag gaaggggggc ttcttcagct ccttcatgaa gaagagaaat
1921 gctcctacac cccccaaacg cagcagctcc ttccgagaaa tggagaatca gccccataag
1981 aaatacgaac tcacggggct tccagagcag gataggatgg caatgaccct tcccaggaac
2041 tgccagaggt ccaaactcca gctggaaagg acagtgtcca cctcttctca gccagaagag
2101 aatgtggaca gggccaatga catgcttcca aaaaaatcag aggaaagtgc tgctccaagc
2161 agggagagac caaaagccaa gttattgccc agaggagcca cagctcttcc tctcagaaca
2221 ccctctgggg atctagccat tacagagaag gaccctccag gggtgggagt ggctggagtg
2281 gcagctgccc ccaagggtaa agagaagaat ggtggggcac gacttgggat ggctggagtt
2341 ccagaggatg gagagcagcc gggctggcct tctccagcca aggctgcccc cgtcctccca
2401 accactcaca accacaaagt gccagtcctt atctcaccca ctctgaaaca cactccagct
2461 gacgtgcagc tcattggcac agactctcag gggaataaat tcaagctctt atctgagcat
2521 caggtcacat cctctggaga caaggaccga ccccgacggg taaaaccaaa gtgtgcccca
2581 cccccaccac cagtgatgag actactgcag catccgtcca tctgctcaga ccctacagaa
2641 gagccaactg ccctaactgc aggacagtcc acatcagaaa cacaggaagg aggaaagaag
2701 gcagctctgg gcgcagtgcc catcagtggg aaagctggga ggccagtgat gcctccacct
2761 caagtgcctc tgcccacatc ttccatctcg ccagccaaaa tggccaatgg cacagcaggt
2821 actaaagtgg ctctgagaaa aaccaaacag gccgctgaga aaatctcagc agacaaaatc
2881 agcaaagagg ccctgctgga atgtgctgac ctactgtcca gtgcactcac ggaacctgtg
2941 cccaacagcc agctggtaga cactggacac cagctgcttg actactgctc aggctatgtg
3001 gactgcatcc ctcaaactcg caacaaattt gccttccgag aggctgtgag caaactggaa
3061 ctcagcctgc aggagctaca ggtttcttca gcagctgctg gtgtgcccgg gacaaaccct
3121 gtccttaata acttattgtc atgtgtacag gaaatcagtg atgtggtgca gaggtag
//