LOCUS FJ542285 3486 bp mRNA linear HUM 22-DEC-2008
DEFINITION Homo sapiens Abl2 isoform 1BSCTL mRNA, complete cds, alternatively
spliced.
ACCESSION FJ542285
VERSION FJ542285.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3486)
AUTHORS Perego,R.A., Corizzato,M., Bianchi,C., Eroini,B. and Bosari,S.
TITLE N- and C-terminal isoforms of Arg quantified by real-time PCR are
specifically expressed in human normal and neoplastic cells, in
neoplastic cell lines, and in HL-60 cell differentiation
JOURNAL Mol. Carcinog. 42 (4), 229-239 (2005)
PUBMED 15765532
REFERENCE 2 (bases 1 to 3486)
AUTHORS Bianchi,C., Torsello,B., Angeloni,V., Bombelli,S., Soldi,M.,
Invernizzi,L., Brambilla,P. and Perego,R.A.
TITLE Eight full-length abelson related gene (Arg) isoforms are
constitutively expressed in caki-1 cell line and cell distribution
of two isoforms has been analyzed after transfection
JOURNAL J. Cell. Biochem. 105 (5), 1219-1227 (2008)
PUBMED 18810762
REFERENCE 3 (bases 1 to 3486)
AUTHORS Perego,R., Bianchi,C., Torsello,B., Angeloni,V., Brambilla,P.,
Bombelli,S. and Invernizzi,L.
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2008) Experimental Medicine, Milano-Bicocca
University, Via Cadore, 48, Monza, MI 20052, Italy
FEATURES Location/Qualifiers
source 1..3486
/db_xref="H-InvDB:HIT000558721"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q24-q25"
/cell_line="renal clear cell carcinoma Caki-1"
CDS 1..3486
/note="lacks the second exon (63 bp); alternatively
spliced; Arg isoform 1BSCTL"
/codon_start=1
/product="Abl2 isoform 1BSCTL"
/protein_id="ACK76603.1"
/translation="MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTET
GFNIFTQHEALHRPYGCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGD
NTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRS
AAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFS
TLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGG
QYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEP
PFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAAR
NCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAF
GVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADR
PSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVE
NKENIEGAQDATENSASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFT
RDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKKYELTGNFSSVASLQHADGFSF
TPAQQEANLVPPKCYGGSFAQRNLCNDDGGGGGGSGTAGGGWSGITGFFTPRLIKKTL
GLRAGKPTASDDTSKPFPRSNSTSSMSSGLPEQDRMAMTLPRNCQRSKLQLERTVSTS
SQPEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPP
GVGVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLI
SPTLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLL
QHPSICSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMPPPQVPLPTS
SISPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSALTEPVPNSQL
VDTGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGTNPVLN
NLLSCVQEISDVVQR"
BASE COUNT 939 a 904 c 912 g 731 t
ORIGIN
1 atggggcagc aggtgggccg cgtcggggaa gctccggggc tccagcagcc tcagccccgc
61 gggatccggg gcagcagtgc agccaggccc tccggccgca ggcgggaccc ggcggggcgc
121 accacagaga ccggcttcaa tatcttcacc cagcatgaag ctttgcatcg tccctatggt
181 tgtgatgttg aaccccaggc actaaatgag gctatcaggt ggagctccaa ggagaacttg
241 ctcggagcca ctgagagtga ccctaatctc ttcgttgcac tttatgattt tgtagcaagt
301 ggtgataaca cactcagcat cactaaaggt gaaaagctac gagtccttgg ttacaaccag
361 aatggtgagt ggagtgaagt tcgctctaag aatgggcagg gctgggtgcc aagcaactac
421 atcaccccag tgaacagcct ggaaaaacac tcctggtacc atggacctgt gtcacgcagt
481 gcagctgagt atctgctcag cagtctaatc aatggcagct tcctggtgcg agaaagtgag
541 agtagccctg ggcagctgtc catctcgctc aggtacgagg gacgtgtgta tcactacagg
601 atcaatacca ctgcagatgg caaggtgtat gtgactgctg agagccgctt cagcaccttg
661 gcagagcttg tacaccatca ctccacagtg gctgatgggc tggtgacaac attacactac
721 ccagcaccca agtgtaataa gcctacagtc tatggtgtgt cccccatcca cgacaaatgg
781 gaaatggagc gaacagatat taccatgaag cacaaacttg ggggcggtca gtatggagag
841 gtttacgttg gcgtctggaa gaaatacagc cttacagttg ctgtgaaaac attgaaggaa
901 gataccatgg aggtagaaga attcctgaaa gaagctgcag taatgaagga aatcaagcat
961 cctaatctgg tacaactttt aggtgtgtgt actttggagc caccatttta cattgtgact
1021 gaatacatgc catacgggaa tttgctggat tacctccgag aatgcaaccg agaagaggtg
1081 actgcagttg tgctgctcta catggccact cagatttctt ctgcaatgga gtacttagag
1141 aagaagaatt tcatccatag agatcttgca gctcgtaact gcctagtggg agaaaaccat
1201 gtggtaaaag tggctgactt tggcttaagt agattgatga ctggagacac ttatactgct
1261 catgctggag ccaaatttcc tattaagtgg acagcaccag agagtcttgc ctacaatacc
1321 ttctcaatta aatctgacgt ctgggctttt ggggtattgt tgtgggaaat tgctacctat
1381 ggaatgtcac catatccagg tattgacctg tctcaggtct atgacctact agaaaaagga
1441 tatcgaatgg aacagcctga gggatgcccc cctaaggttt atgaacttat gagagcatgc
1501 tggaagtgga gccctgccga taggccctct tttgctgaaa cacaccaagc ttttgaaacc
1561 atgttccatg actccagcat ttctgaagag gtagctgagg agcttgggag agccgcctcc
1621 tcgtcatctg ttgttccata cctgccccgg ctacctatac ttccttccaa gactcggaca
1681 ctgaagaaac aggtggagaa caaggagaac attgaagggg cacaagatgc cacagaaaat
1741 tctgcttcca gtttagcacc agggttcatc agaggtgcac aggcctctag tggatcccca
1801 gcactgcctc gaaagcaaag agacaagtca cccagcagcc tcttggaaga tgccaaagag
1861 acatgcttca ccagggatag gaaggggggc ttcttcagct ccttcatgaa gaagagaaat
1921 gctcctacac cccccaaacg cagcagctcc ttccgagaaa tggagaatca gccccataag
1981 aaatacgaac tcacgggtaa cttctcatct gttgcttctc tacagcatgc tgatgggttc
2041 tctttcactc ctgcccagca agaggcgaat ctggtgccac ccaagtgcta tggggggagc
2101 tttgcacaga ggaacctctg taatgacgac ggtggtgggg gtgggggcag tggcactgct
2161 gggggtgggt ggtctggcat cacaggcttc tttacaccac gcttaatcaa aaagacactg
2221 ggcttacgag caggtaaacc cacagccagt gatgacactt ccaagccttt tccaaggtca
2281 aactctacat cttccatgtc ctcagggctt ccagagcagg ataggatggc aatgaccctt
2341 cccaggaact gccagaggtc caaactccag ctggaaagga cagtgtccac ctcttctcag
2401 ccagaagaga atgtggacag ggccaatgac atgcttccaa aaaaatcaga ggaaagtgct
2461 gctccaagca gggagagacc aaaagccaag ttattgccca gaggagccac agctcttcct
2521 ctcagaacac cctctgggga tctagccatt acagagaagg accctccagg ggtgggagtg
2581 gctggagtgg cagctgcccc caagggtaaa gagaagaatg gtggggcacg acttgggatg
2641 gctggagttc cagaggatgg agagcagccg ggctggcctt ctccagccaa ggctgccccc
2701 gtcctcccaa ccactcacaa ccacaaagtg ccagtcctta tctcacccac tctgaaacac
2761 actccagctg acgtgcagct cattggcaca gactctcagg ggaataaatt caagctctta
2821 tctgagcatc aggtcacatc ctctggagac aaggaccgac cccgacgggt aaaaccaaag
2881 tgtgccccac ccccaccacc agtgatgaga ctactgcagc atccgtccat ctgctcagac
2941 cctacagaag agccaactgc cctaactgca ggacagtcca catcagaaac acaggaagga
3001 ggaaagaagg cagctctggg cgcagtgccc atcagtggga aagctgggag gccagtgatg
3061 cctccacctc aagtgcctct gcccacatct tccatctcgc cagccaaaat ggccaatggc
3121 acagcaggta ctaaagtggc tctgagaaaa accaaacagg ccgctgagaa aatctcagca
3181 gacaaaatca gcaaagaggc cctgctggaa tgtgctgacc tactgtccag tgcactcacg
3241 gaacctgtgc ccaacagcca gctggtagac actggacacc agctgcttga ctactgctca
3301 ggctatgtgg actgcatccc tcaaactcgc aacaaatttg ccttccgaga ggctgtgagc
3361 aaactggaac tcagcctgca ggagctacag gtttcttcag cagctgctgg tgtgcccggg
3421 acaaaccctg tccttaataa cttattgtca tgtgtacagg aaatcagtga tgtggtgcag
3481 aggtag
//