LOCUS FJ542284 3240 bp mRNA linear HUM 22-DEC-2008
DEFINITION Homo sapiens Abl2 isoform 1BLCTS mRNA, complete cds, alternatively
spliced.
ACCESSION FJ542284
VERSION FJ542284.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3240)
AUTHORS Perego,R.A., Corizzato,M., Bianchi,C., Eroini,B. and Bosari,S.
TITLE N- and C-terminal isoforms of Arg quantified by real-time PCR are
specifically expressed in human normal and neoplastic cells, in
neoplastic cell lines, and in HL-60 cell differentiation
JOURNAL Mol. Carcinog. 42 (4), 229-239 (2005)
PUBMED 15765532
REFERENCE 2 (bases 1 to 3240)
AUTHORS Bianchi,C., Torsello,B., Angeloni,V., Bombelli,S., Soldi,M.,
Invernizzi,L., Brambilla,P. and Perego,R.A.
TITLE Eight full-length abelson related gene (Arg) isoforms are
constitutively expressed in caki-1 cell line and cell distribution
of two isoforms has been analyzed after transfection
JOURNAL J. Cell. Biochem. 105 (5), 1219-1227 (2008)
PUBMED 18810762
REFERENCE 3 (bases 1 to 3240)
AUTHORS Perego,R., Bianchi,C., Torsello,B., Angeloni,V., Brambilla,P.,
Silvia,B. and Lara,I.
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2008) Experimental Medicine, Milano-Bicocca
University, Via Cadore, 48, Monza, MI 20052, Italy
FEATURES Location/Qualifiers
source 1..3240
/db_xref="H-InvDB:HIT000558720"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q24-q25"
/cell_line="renal clear cell carcinoma Caki-1"
CDS 1..3240
/note="lacks 309 bp in the 3' end that involves the
internal actin binding domain; alternatively spliced; Arg
isoform 1BLCTS"
/codon_start=1
/product="Abl2 isoform 1BLCTS"
/protein_id="ACK76602.1"
/translation="MGQQVGRVGEAPGLQQPQPRGIRGSSAARPSGRRRDPAGRTTET
GFNIFTQHDHFASCVEDGFEGDKTGGSSPEALHRPYGCDVEPQALNEAIRWSSKENLL
GATESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRSKNGQGWVPSN
YITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSISLRYEGRVY
HYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKPTVYGVSP
IHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEFLKEAA
VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQ
ISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFPIK
WTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPE
GCPPKVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAEELGRAASSSSVV
PYLPRLPILPSKTRTLKKQVENKENIEGAQDATENSASSLAPGFIRGAQASSGSPALP
RKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKRNAPTPPKRSSSFREMENQPHKK
YELTGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQPEENVDRANDMLPKKSEESAAP
SRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGVGVAGVAAAPKGKEKNGGARLGM
AGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISPTLKHTPADVQLIGTDSQGNKFK
LLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQHPSICSDPTEEPTALTAGQSTSE
TQEGGKKAALGAVPISGKAGRPVMPPPQVPLPTSSISPAKMANGTAGTKVALRKTKQA
AEKISADKISKEALLECADLLSSALTEPVPNSQLVDTGHQLLDYCSGYVDCIPQTRNK
FAFREAVSKLELSLQELQVSSAAAGVPGTNPVLNNLLSCVQEISDVVQR"
BASE COUNT 887 a 833 c 851 g 669 t
ORIGIN
1 atggggcagc aggtgggccg cgtcggggaa gctccggggc tccagcagcc tcagccccgc
61 gggatccggg gcagcagtgc agccaggccc tccggccgca ggcgggaccc ggcggggcgc
121 accacagaga ccggcttcaa tatcttcacc cagcatgatc actttgccag ctgtgtggag
181 gatggatttg agggagacaa gactggaggc agtagtccag aagctttgca tcgtccctat
241 ggttgtgatg ttgaacccca ggcactaaat gaggctatca ggtggagctc caaggagaac
301 ttgctcggag ccactgagag tgaccctaat ctcttcgttg cactttatga ttttgtagca
361 agtggtgata acacactcag catcactaaa ggtgaaaagc tacgagtcct tggttacaac
421 cagaatggtg agtggagtga agttcgctct aagaatgggc agggctgggt gccaagcaac
481 tacatcaccc cagtgaacag cctggaaaaa cactcctggt accatggacc tgtgtcacgc
541 agtgcagctg agtatctgct cagcagtcta atcaatggca gcttcctggt gcgagaaagt
601 gagagtagcc ctgggcagct gtccatctcg ctcaggtacg agggacgtgt gtatcactac
661 aggatcaata ccactgcaga tggcaaggtg tatgtgactg ctgagagccg cttcagcacc
721 ttggcagagc ttgtacacca tcactccaca gtggctgatg ggctggtgac aacattacac
781 tacccagcac ccaagtgtaa taagcctaca gtctatggtg tgtcccccat ccacgacaaa
841 tgggaaatgg agcgaacaga tattaccatg aagcacaaac ttgggggcgg tcagtatgga
901 gaggtttacg ttggcgtctg gaagaaatac agccttacag ttgctgtgaa aacattgaag
961 gaagatacca tggaggtaga agaattcctg aaagaagctg cagtaatgaa ggaaatcaag
1021 catcctaatc tggtacaact tttaggtgtg tgtactttgg agccaccatt ttacattgtg
1081 actgaataca tgccatacgg gaatttgctg gattacctcc gagaatgcaa ccgagaagag
1141 gtgactgcag ttgtgctgct ctacatggcc actcagattt cttctgcaat ggagtactta
1201 gagaagaaga atttcatcca tagagatctt gcagctcgta actgcctagt gggagaaaac
1261 catgtggtaa aagtggctga ctttggctta agtagattga tgactggaga cacttatact
1321 gctcatgctg gagccaaatt tcctattaag tggacagcac cagagagtct tgcctacaat
1381 accttctcaa ttaaatctga cgtctgggct tttggggtat tgttgtggga aattgctacc
1441 tatggaatgt caccatatcc aggtattgac ctgtctcagg tctatgacct actagaaaaa
1501 ggatatcgaa tggaacagcc tgagggatgc ccccctaagg tttatgaact tatgagagca
1561 tgctggaagt ggagccctgc cgataggccc tcttttgctg aaacacacca agcttttgaa
1621 accatgttcc atgactccag catttctgaa gaggtagctg aggagcttgg gagagccgcc
1681 tcctcgtcat ctgttgttcc atacctgccc cggctaccta tacttccttc caagactcgg
1741 acactgaaga aacaggtgga gaacaaggag aacattgaag gggcacaaga tgccacagaa
1801 aattctgctt ccagtttagc accagggttc atcagaggtg cacaggcctc tagtggatcc
1861 ccagcactgc ctcgaaagca aagagacaag tcacccagca gcctcttgga agatgccaaa
1921 gagacatgct tcaccaggga taggaagggg ggcttcttca gctccttcat gaagaagaga
1981 aatgctccta caccccccaa acgcagcagc tccttccgag aaatggagaa tcagccccat
2041 aagaaatacg aactcacggg gcttccagag caggatagga tggcaatgac ccttcccagg
2101 aactgccaga ggtccaaact ccagctggaa aggacagtgt ccacctcttc tcagccagaa
2161 gagaatgtgg acagggccaa tgacatgctt ccaaaaaaat cagaggaaag tgctgctcca
2221 agcagggaga gaccaaaagc caagttattg cccagaggag ccacagctct tcctctcaga
2281 acaccctctg gggatctagc cattacagag aaggaccctc caggggtggg agtggctgga
2341 gtggcagctg cccccaaggg taaagagaag aatggtgggg cacgacttgg gatggctgga
2401 gttccagagg atggagagca gccgggctgg ccttctccag ccaaggctgc ccccgtcctc
2461 ccaaccactc acaaccacaa agtgccagtc cttatctcac ccactctgaa acacactcca
2521 gctgacgtgc agctcattgg cacagactct caggggaata aattcaagct cttatctgag
2581 catcaggtca catcctctgg agacaaggac cgaccccgac gggtaaaacc aaagtgtgcc
2641 ccacccccac caccagtgat gagactactg cagcatccgt ccatctgctc agaccctaca
2701 gaagagccaa ctgccctaac tgcaggacag tccacatcag aaacacagga aggaggaaag
2761 aaggcagctc tgggcgcagt gcccatcagt gggaaagctg ggaggccagt gatgcctcca
2821 cctcaagtgc ctctgcccac atcttccatc tcgccagcca aaatggccaa tggcacagca
2881 ggtactaaag tggctctgag aaaaaccaaa caggccgctg agaaaatctc agcagacaaa
2941 atcagcaaag aggccctgct ggaatgtgct gacctactgt ccagtgcact cacggaacct
3001 gtgcccaaca gccagctggt agacactgga caccagctgc ttgactactg ctcaggctat
3061 gtggactgca tccctcaaac tcgcaacaaa tttgccttcc gagaggctgt gagcaaactg
3121 gaactcagcc tgcaggagct acaggtttct tcagcagctg ctggtgtgcc cgggacaaac
3181 cctgtcctta ataacttatt gtcatgtgta caggaaatca gtgatgtggt gcagaggtag
//