LOCUS FJ542283 3132 bp mRNA linear HUM 22-DEC-2008
DEFINITION Homo sapiens Abl2 isoform 1ASCTS mRNA, complete cds, alternatively
spliced.
ACCESSION FJ542283
VERSION FJ542283.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3132)
AUTHORS Perego,R.A., Corizzato,M., Bianchi,C., Eroini,B. and Bosari,S.
TITLE N- and C-terminal isoforms of Arg quantified by real-time PCR are
specifically expressed in human normal and neoplastic cells, in
neoplastic cell lines, and in HL-60 cell differentiation
JOURNAL Mol. Carcinog. 42 (4), 229-239 (2005)
PUBMED 15765532
REFERENCE 2 (bases 1 to 3132)
AUTHORS Bianchi,C., Torsello,B., Angeloni,V., Bombelli,S., Soldi,M.,
Invernizzi,L., Brambilla,P. and Perego,R.A.
TITLE Eight full-length abelson related gene (Arg) isoforms are
constitutively expressed in caki-1 cell line and cell distribution
of two isoforms has been analyzed after transfection
JOURNAL J. Cell. Biochem. 105 (5), 1219-1227 (2008)
PUBMED 18810762
REFERENCE 3 (bases 1 to 3132)
AUTHORS Perego,R., Bianchi,C., Torsello,B., Angeloni,V., Brambilla,P.,
Bombelli,S. and Invernizzi,L.
TITLE Direct Submission
JOURNAL Submitted (11-DEC-2008) Experimental Medicine, Milano-Bicocca
University, Via Cadore, 48, Monza, MI 20052, Italy
FEATURES Location/Qualifiers
source 1..3132
/db_xref="H-InvDB:HIT000558719"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q24-q25"
/cell_line="renal clear cell carcinoma Caki-1"
CDS 1..3132
/note="lacks the second exon (63 bp) and 309 bp in the 3'
end that involves the internal actin binding domain;
alternatively spliced; Arg isoform 1ASCTS"
/codon_start=1
/product="Abl2 isoform 1ASCTS"
/protein_id="ACK76601.1"
/translation="MVLGTVLLPPNTYGRDQDTSLCCLCTEASESALPDLTEALHRPY
GCDVEPQALNEAIRWSSKENLLGATESDPNLFVALYDFVASGDNTLSITKGEKLRVLG
YNQNGEWSEVRSKNGQGWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFL
VRESESSPGQLSISLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADG
LVTTLHYPAPKCNKPTVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSL
TVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLL
DYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADF
GLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPY
PGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWSPADRPSFAETHQAFETMFH
DSSISEEVAEELGRAASSSSVVPYLPRLPILPSKTRTLKKQVENKENIEGAQDATENS
ASSLAPGFIRGAQASSGSPALPRKQRDKSPSSLLEDAKETCFTRDRKGGFFSSFMKKR
NAPTPPKRSSSFREMENQPHKKYELTGLPEQDRMAMTLPRNCQRSKLQLERTVSTSSQ
PEENVDRANDMLPKKSEESAAPSRERPKAKLLPRGATALPLRTPSGDLAITEKDPPGV
GVAGVAAAPKGKEKNGGARLGMAGVPEDGEQPGWPSPAKAAPVLPTTHNHKVPVLISP
TLKHTPADVQLIGTDSQGNKFKLLSEHQVTSSGDKDRPRRVKPKCAPPPPPVMRLLQH
PSICSDPTEEPTALTAGQSTSETQEGGKKAALGAVPISGKAGRPVMPPPQVPLPTSSI
SPAKMANGTAGTKVALRKTKQAAEKISADKISKEALLECADLLSSALTEPVPNSQLVD
TGHQLLDYCSGYVDCIPQTRNKFAFREAVSKLELSLQELQVSSAAAGVPGTNPVLNNL
LSCVQEISDVVQR"
BASE COUNT 870 a 800 c 792 g 670 t
ORIGIN
1 atggtccttg ggacagttct ccttccacct aatacttatg gcagagatca ggacacttca
61 ctttgctgcc tgtgcactga ggcctcagaa tctgctctac ccgacttaac agaagctttg
121 catcgtccct atggttgtga tgttgaaccc caggcactaa atgaggctat caggtggagc
181 tccaaggaga acttgctcgg agccactgag agtgacccta atctcttcgt tgcactttat
241 gattttgtag caagtggtga taacacactc agcatcacta aaggtgaaaa gctacgagtc
301 cttggttaca accagaatgg tgagtggagt gaagttcgct ctaagaatgg gcagggctgg
361 gtgccaagca actacatcac cccagtgaac agcctggaaa aacactcctg gtaccatgga
421 cctgtgtcac gcagtgcagc tgagtatctg ctcagcagtc taatcaatgg cagcttcctg
481 gtgcgagaaa gtgagagtag ccctgggcag ctgtccatct cgctcaggta cgagggacgt
541 gtgtatcact acaggatcaa taccactgca gatggcaagg tgtatgtgac tgctgagagc
601 cgcttcagca ccttggcaga gcttgtacac catcactcca cagtggctga tgggctggtg
661 acaacattac actacccagc acccaagtgt aataagccta cagtctatgg tgtgtccccc
721 atccacgaca aatgggaaat ggagcgaaca gatattacca tgaagcacaa acttgggggc
781 ggtcagtatg gagaggttta cgttggcgtc tggaagaaat acagccttac agttgctgtg
841 aaaacattga aggaagatac catggaggta gaagaattcc tgaaagaagc tgcagtaatg
901 aaggaaatca agcatcctaa tctggtacaa cttttaggtg tgtgtacttt ggagccacca
961 ttttacattg tgactgaata catgccatac gggaatttgc tggattacct ccgagaatgc
1021 aaccgagaag aggtgactgc agttgtgctg ctctacatgg ccactcagat ttcttctgca
1081 atggagtact tagagaagaa gaatttcatc catagagatc ttgcagctcg taactgccta
1141 gtgggagaaa accatgtggt aaaagtggct gactttggct taagtagatt gatgactgga
1201 gacacttata ctgctcatgc tggagccaaa tttcctatta agtggacagc accagagagt
1261 cttgcctaca ataccttctc aattaaatct gacgtctggg cttttggggt attgttgtgg
1321 gaaattgcta cctatggaat gtcaccatat ccaggtattg acctgtctca ggtctatgac
1381 ctactagaaa aaggatatcg aatggaacag cctgagggat gcccccctaa ggtttatgaa
1441 cttatgagag catgctggaa gtggagccct gccgataggc cctcttttgc tgaaacacac
1501 caagcttttg aaaccatgtt ccatgactcc agcatttctg aagaggtagc tgaggagctt
1561 gggagagccg cctcctcgtc atctgttgtt ccatacctgc cccggctacc tatacttcct
1621 tccaagactc ggacactgaa gaaacaggtg gagaacaagg agaacattga aggggcacaa
1681 gatgccacag aaaattctgc ttccagttta gcaccagggt tcatcagagg tgcacaggcc
1741 tctagtggat ccccagcact gcctcgaaag caaagagaca agtcacccag cagcctcttg
1801 gaagatgcca aagagacatg cttcaccagg gataggaagg ggggcttctt cagctccttc
1861 atgaagaaga gaaatgctcc tacacccccc aaacgcagca gctccttccg agaaatggag
1921 aatcagcccc ataagaaata cgaactcacg gggcttccag agcaggatag gatggcaatg
1981 acccttccca ggaactgcca gaggtccaaa ctccagctgg aaaggacagt gtccacctct
2041 tctcagccag aagagaatgt ggacagggcc aatgacatgc ttccaaaaaa atcagaggaa
2101 agtgctgctc caagcaggga gagaccaaaa gccaagttat tgcccagagg agccacagct
2161 cttcctctca gaacaccctc tggggatcta gccattacag agaaggaccc tccaggggtg
2221 ggagtggctg gagtggcagc tgcccccaag ggtaaagaga agaatggtgg ggcacgactt
2281 gggatggctg gagttccaga ggatggagag cagccgggct ggccttctcc agccaaggct
2341 gcccccgtcc tcccaaccac tcacaaccac aaagtgccag tccttatctc acccactctg
2401 aaacacactc cagctgacgt gcagctcatt ggcacagact ctcaggggaa taaattcaag
2461 ctcttatctg agcatcaggt cacatcctct ggagacaagg accgaccccg acgggtaaaa
2521 ccaaagtgtg ccccaccccc accaccagtg atgagactac tgcagcatcc gtccatctgc
2581 tcagacccta cagaagagcc aactgcccta actgcaggac agtccacatc agaaacacag
2641 gaaggaggaa agaaggcagc tctgggcgca gtgcccatca gtgggaaagc tgggaggcca
2701 gtgatgcctc cacctcaagt gcctctgccc acatcttcca tctcgccagc caaaatggcc
2761 aatggcacag caggtactaa agtggctctg agaaaaacca aacaggccgc tgagaaaatc
2821 tcagcagaca aaatcagcaa agaggccctg ctggaatgtg ctgacctact gtccagtgca
2881 ctcacggaac ctgtgcccaa cagccagctg gtagacactg gacaccagct gcttgactac
2941 tgctcaggct atgtggactg catccctcaa actcgcaaca aatttgcctt ccgagaggct
3001 gtgagcaaac tggaactcag cctgcaggag ctacaggttt cttcagcagc tgctggtgtg
3061 cccgggacaa accctgtcct taataactta ttgtcatgtg tacaggaaat cagtgatgtg
3121 gtgcagaggt ag
//