LOCUS FJ472844 1569 bp mRNA linear HUM 02-APR-2010
DEFINITION Homo sapiens plasticity-related protein 5 (PRG5) mRNA, complete
cds.
ACCESSION FJ472844
VERSION FJ472844.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1569)
AUTHORS Broggini,T., Nitsch,R. and Savaskan,N.E.
TITLE Plasticity-related gene 5 (PRG5) induces filopodia and neurite
growth and impedes lysophosphatidic acid- and nogo-A-mediated
axonal retraction
JOURNAL Mol. Biol. Cell 21 (4), 521-537 (2010)
PUBMED 20032306
REFERENCE 2 (bases 1 to 1569)
AUTHORS Broggini,T. and Savaskan,N.E.
TITLE Direct Submission
JOURNAL Submitted (20-NOV-2008) Molecular Biology, Brain Research
Institute, Winterthurerstrassse 190, Zurich, ZH CH-8057,
Switzerland
FEATURES Location/Qualifiers
source 1..1569
/db_xref="H-InvDB:HIT000558627"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
gene 1..1569
/gene="PRG5"
CDS 223..1188
/gene="PRG5"
/note="six transmembrane integral membrane protein; member
of the plasticity-related gene family which is part of the
lipid phosphate phosphatase/phosphotransferase (LPP/LPT)
superfamily; implicated in axon growth and neuronal
plasticity processes; similar to GenBank Accession Numbers
AY512657 and EU792473"
/codon_start=1
/product="plasticity-related protein 5"
/protein_id="ACJ60628.1"
/translation="MPLLPAALTSSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFF
CHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEK
TILTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYT
ALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKG
TRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKG
RQAENEHIHMDNLAQMPMISIPRVESPLEKVTSVQNHITAFAEVT"
BASE COUNT 392 a 419 c 355 g 403 t
ORIGIN
1 ggggctcgtc cgggggtagc cgcctcctct gcagcctgcc ggcgcctcga agcccggacc
61 tgcctccgcc tcttcctcca gcggctccat cccgcctccc gtgcctcgtc ctcccgccgc
121 ctccgccgcc gcgcccccgg tggctgcctc ggcggaccgg ggagggggcc caccgcgtcg
181 accgcccgct cggctcggct cggcccggcc cgggaggcgt gcatgcccct gctgcccgcg
241 gcgctcacca gcagcatgct ctatttccag atggtgatca tggcagggac ggtgatgctg
301 gcgtactact tcgagtatac ggacacgttc accgtgaacg tgcagggctt cttctgccac
361 gacagcgcct accgcaaacc ctacccgggc ccggaggaca gcagcgccgt gccccccgtg
421 ctcctctact cgctggccgc cggggtcccc gtgctcgtga taatagttgg agaaactgct
481 gtcttttgcc tacaactagc cacaagggat tttgaaaacc aggaaaaaac tattttaact
541 ggagactgtt gctatataaa cccgctggtg cgccgaactg tccgatttct tggaatttat
601 acatttggac tgtttgctac agatatcttt gtaaatgctg gacaagtagt cacaggaaat
661 ctggccccac atttccttgc cctgtgtaag cccaattata cagcacttgg atgtcagcag
721 tatacacaat tcatcagtgg ggaagaggcc tgtactggca acccagatct catcatgaga
781 gcccgaaaaa cctttccatc caaagaagca gctctcagtg tctatgcagc tatgtatctg
841 accatgtaca tcaccaacac aatcaaagcc aagggaacca gacttgctaa gccagttcta
901 tgcttgggct taatgtgttt ggcatttctt actggactca acagagtagc agaatatcga
961 aatcattggt cagatgttat agcaggcttt ctggttggaa tatctatagc agtatttctg
1021 gttgtgtgcg tggtgaataa tttcaaaggg agacaagcag aaaatgagca tatacacatg
1081 gataatctgg cacagatgcc aatgatcagc attcctcgag tagaaagtcc tttggaaaag
1141 gtaacatctg tacagaacca catcactgcc ttcgcagaag tcacatgata tcgaagcaga
1201 tggtttttca ctgcattgga catcatccct ttttaccatc cattcataac acccaaagtt
1261 tgtttgattg caagtgaagt ttataaagtt gtttaataat ttttataatt ttaaaatcaa
1321 tgtcaaccta tctgtttccc ccactagact gtgagctcct cgagggcagg attgtctttt
1381 tttttctgtg tccccagcac ttacaacaaa gcctagcaca aagtaggtgt tcaacaaaaa
1441 tgtgatgacc aaatgaacaa aattcttaaa taaaacattc actttagttt ctcacagaat
1501 cattgcaatt atgttaaaag aaatctctac ataaatcgta tttgtgtatg aaaaccttct
1561 attttgggc
//