LOCUS FJ462711 2966 bp mRNA linear HUM 01-JAN-2010
DEFINITION Homo sapiens mitochondrial aldehyde dehydrogenase 4 family member
A1 transcript variant ALDH4A1_v6 (ALDH4A1) mRNA, complete cds;
nuclear gene for mitochondrial product.
ACCESSION FJ462711
VERSION FJ462711.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2966)
AUTHORS Stagos,D. and Vasiliou,V.
TITLE A novel transcript variant of human ALDH4A1 gene
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2966)
AUTHORS Stagos,D. and Vasiliou,V.
TITLE Direct Submission
JOURNAL Submitted (14-NOV-2008) School of Pharmacy, University of Colorado
Denver, 12700 E 19th Ave, Aurora, CO 80045, USA
FEATURES Location/Qualifiers
source 1..2966
/db_xref="H-InvDB:HIT000646012"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p36"
/cell_type="endothelial cells"
gene 1..2966
/gene="ALDH4A1"
CDS 15..1553
/gene="ALDH4A1"
/EC_number="1.5.1.12"
/note="mitochondrial delta-1-pyrroline 5-carboxylate
dehydrogenase; P5C dehydrogenase"
/codon_start=1
/product="mitochondrial aldehyde dehydrogenase 4 family
member A1 transcript variant ALDH4A1_v6"
/protein_id="ACN89883.1"
/translation="MLLPAPALRRALLSRPWTGAGLRWKHTSSLKVANEPVLAFTQGS
PERDALQKALKDLKGRMEAIPCVVGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKSLL
NKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEI
DAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGGN
LAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSS
EHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSADVESVVS
GTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVI
DAKEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAA
GNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWSY
AYMQ"
BASE COUNT 540 a 905 c 899 g 622 t
ORIGIN
1 ggcacgaggc cgagatgctg ctgccggcgc ccgcgctccg ccgcgccctg ctgtcccgcc
61 cctggaccgg ggccggcctg cggtggaagc acacctcctc cctgaaggtg gccaacgagc
121 ccgtcttagc cttcacgcag ggcagccctg agcgagatgc cctgcaaaag gccttgaagg
181 acctgaaggg ccggatggaa gccatcccat gcgtggtggg ggatgaggag gtgtggacgt
241 cggacgtgca gtaccaagtg tcgcctttta accatggaca taaggtggcc aagttctgtt
301 atgcagacaa gagcctgctc aacaaagcca ttgaggctgc cctggctgcc cggaaagagt
361 gggacctgaa gcctattgca gaccgggccc agatcttcct gaaggcggca gacatgctga
421 gtgggccgcg cagggctgag atcctcgcca agaccatggt gggacagggt aagaccgtga
481 tccaagcgga gattgacgct gcagcggaac tcatcgactt cttccggttc aatgccaagt
541 atgcggtgga gctggagggg cagcagccca tcagcgtgcc cccgagcacc aacagcacgg
601 tgtaccgggg tctggagggc ttcgtggcgg ccatctcgcc ctttaacttc actgcaatcg
661 gcggcaacct ggcgggggca ccggccctga tgggcaacgt ggtcctatgg aagcccagtg
721 acactgccat gctggccagc tatgctgtct accgcatcct tcgggaggct ggcctgcccc
781 ccaacatcat ccagtttgtg ccagctgatg ggcccctatt tggggacact gtcaccagct
841 cagagcacct ctgtggcatc aacttcacag gcagtgtgcc caccttcaaa cacctgtgga
901 agcaggtggc ccagaacctg gaccggttcc acaccttccc acgcctggct ggagagtgcg
961 gcggaaagaa cttccacttc gtgcaccgct cggccgacgt ggagagcgtg gtgagcggga
1021 ccctccgctc agccttcgag tacggtggcc agaagtgttc cgcctgctcg cgtctctacg
1081 tgccgcactc gctgtggccg cagatcaaag ggcggctgct ggaggagcac agtcggatca
1141 aagtgggcga ccctgcagag gattttggga ccttcttctc tgcagtgatt gatgccaagg
1201 agatcttcgg gcctgtactg tctgtgtacg tctacccgga cgacaagtac aaggagacgc
1261 tgcagctggt tgacagcacc accagctatg gcctcacggg ggcagtgttc tcccaggata
1321 aggacgtcgt gcaggaggcc acaaaggtgc tgaggaatgc tgccggcaac ttctacatca
1381 acgacaagtc cactggctcg atagtgggcc agcagccctt tgggggggcc cgagcctctg
1441 gaaccaatga caagccaggg ggcccacact acatcctgcg ctggacgtcg ccgcaggtca
1501 tcaaggagac acataagccc ctgggggact ggagctacgc gtacatgcag tgagcccctc
1561 tcgggctcca ccgtccagct gtctgtccgt ccaggtggcc gacctcactg cacagacccc
1621 actccagccc ctccacccct tcttcatgca cagctgcctt tctataatcc gggcttgact
1681 cccttcttac cactgtattc tggcctctcc catgcctcag gctctggttt gagatcgtgc
1741 tggggaggaa catggccact accccttatc ccatcggcca tgtgggaggt atgaccctgg
1801 tgcctggcag gttctccctc tgccctccac tgggcccagt ggctcaggga cctggggaaa
1861 ggagatggag cagctcttgg gatcctttgg ggaaaaggag gccattctgg gccccttggc
1921 aaacctcacc actcacagag gctcctggcc ttgatccctg cccctccagg tgtccagggt
1981 aaagtgtaac tcagactgac ctgtggggca cagggggcac cagctggcct tgccctctct
2041 ggtctgggct gtctaccttc ctcactgtat ctttgcccag acccacctgg gccagtagtc
2101 ccctgtcccc agccacacac cttagatgct ggcatgcctt actccaggtg cctgtgtttg
2161 gccgaggcct gtgtgattcc cggtctgcac cacatggcgg ggttgggggg ccgctggagg
2221 ccacctgcca aggcgtggga tgggatggtc ctgccggttt aggccgtgat tctggaaaac
2281 cttggatggg ccttcgtcct atgtcagcct tccctttgat cctcaggccc tacctgtaga
2341 gacctccact cctagagcca gtctcagggt ctgggatttc cctgcaggag ctcagccacc
2401 actgtgccat ggtgacacag gccaaggcag acattggccc tcccttctcc cagcccccag
2461 aggcctggcc ttgggttcgt cagcatgggc cgaggacgtt gcctgtagaa tcctcctctg
2521 cctgggagtg gctctgtgtg gaccagtccc tcactggccc attctttttt tgacgcagcc
2581 aatctgtgac cacgattcct cccacagatg cctcctgctt ggattctgag tggtcagaga
2641 tctgtaaagc atgactttca aggatggttc ttaggggact gtgaaagtgt tgggtcttcc
2701 tccaggatgc ctgcatggga ccccacccgg agctggtgtg gccattcccc aagtgccact
2761 ggcccatgga tgggggtggg tgctggtgcc agctgggctg ggtgtgggtt ctgtgtcctt
2821 ccaggatatg tgtcatttcc catgaggggc cggggcaggt ggctgggtgg gggcacaggc
2881 tggagtattc ttagttctac tggttctaca ctgtgaggtg gcaatgggat ttgctcagat
2941 gccacccaat aaaatgcctg ttactt
//