LOCUS FJ416331 10597 bp mRNA linear HUM 14-NOV-2008
DEFINITION Homo sapiens spacemaker (EYS) mRNA, complete cds.
ACCESSION FJ416331
VERSION FJ416331.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10597)
AUTHORS Abd El-Aziz,M.M., Barragan,I., O'Driscoll,C.A., Goodstadt,L.,
Prigmore,E., Borrego,S., Mena,M., Pieras,J.I., El-Ashry,M.F.,
Safieh,L.A., Shah,A., Cheetham,M.E., Carter,N.P., Chakarova,C.,
Ponting,C.P., Bhattacharya,S.S. and Antinolo,G.
TITLE EYS, encoding an ortholog of Drosophila spacemaker, is mutated in
autosomal recessive retinitis pigmentosa
JOURNAL Nat. Genet. 40 (11), 1285-1287 (2008)
PUBMED 18836446
REFERENCE 2 (bases 1 to 10597)
AUTHORS Abd El-Aziz,M.M., Barragan,I., O'Driscoll,C.A., Goodstadt,L.,
Prigmore,E., Borrego,S., Mena,M., Pieras,J.I., El-Ashry,M.F., Abu
Safieh,L., Shah,A., Cheetham,M.E., Carter,N.P., Chakarova,C.,
Ponting,C.P., Bhattacharya,S.S. and Antinolo,G.
TITLE Direct Submission
JOURNAL Submitted (24-OCT-2008) Unidad Clinica de Genetica, Reproduccion y
Medicina Fetal, Hospitales Universitarios Virgen del Rocio, Avda.
Manuel Siurot s/n, Seville 41013, Spain
FEATURES Location/Qualifiers
source 1..10597
/db_xref="H-InvDB:HIT000558568"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q12"
gene 1..10597
/gene="EYS"
CDS 547..9981
/gene="EYS"
/note="SPAM; similar to Drosophila melanogaster eyes shut"
/codon_start=1
/product="spacemaker"
/protein_id="ACJ37365.1"
/translation="MTDKSIVILSLMVFHSSFINGKTCRRQLVEEWHPQPSSYVVNWT
LTENICLDFYRDCWFLGVNTKIDTSGNQAVPQICPLQIQLGDILVISSEPSLQFPEIN
LMNVSETSFVGCVQNTTTEDQLLFGCRLKGMHTVNSKWLSVGTHYFITVMASGPSPCP
LGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDACS
FKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSN
SFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVS
EFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDY
PCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKN
VYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCT
EDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLEN
TTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALS
HNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDI
DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILN
ACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECT
SGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLL
HNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRC
ICRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKI
SPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDC
KSGFFGTHCETNANDCLSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPC
MNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFD
CRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELECIP
NSCVHELCMENEPGSTCLCTPGFMTCSIGLLCGDEIRRITCLTPIFQRTDPISTQTYT
IPPSETLVSSFPSIKATRIPAIMDTYPVDQGPKQTGIVKHDILPTTGLATLRISTPLE
SYLLQELIVTRELSAKHSLLSSADVSSSRFLNFGIRDPAQIVQDKTSVSHMPIRTSAA
TLGFFFPDRRARTPFIMSSLMSDFIFPTQSLLFENCQTVALSATPTTSVIRSIPGADI
ELNRQSLLSRGFLLIAASISATPVVSRGAQEDIEEYSADSLISRREHWRLLSPSMSPI
FPAKVIISKQVTILNSSALHRFSTKAFNPSEYQAITEASSNQRLTNIKSQAADSLREL
SQTCATCSMTEIKSSREFSDQVLHSKQSHFYETFWMNSAILASWYALMGAQTITSGHS
FSSATEITPSVAFTEVPSLFPSKKSAKRTILSSSLEESITLSSNLDVNLCLDKTCLSI
VPSQTISSDLMNSDLTSKMTTDELSVSENILKLLKIRQYGITMGPTEVLNQESLLDME
KSKGSHTLFKLHPSDSSLDFELNLQIYPDVTLKTYSEITHANDFKNNLPPLTGSVPDF
SEVTTNVAFYTVSATPALSIQTSSSMSVIRPDWPYFTDYMTSLKKEVKTSSEWSKWEL
QPSVQYQEFPTASRHLPFTRSLTLSSLESILAPQRLMISDFSCVRYYGDSYLEFQNVA
LNPQNNISLEFQTFSSYGLLLYVKQDSNLVDGFFIQLFIENGTLKYHFYCPGEAKFKS
INTTVRVDNGQKYTLLIRQELDPCNAELTILGRNTQICESINHVLGKPLPKSGSVFIG
GFPDLHGKIQMPVPVKNFTGCIEVIEINNWRSFIPSKAVKNYHINNCRSQGFMLSPTA
SFVDASDVTQGVDTMWTSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPL
HFTGRFCEKDAGLFFPSFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILY
SNGNNCGKQFLHLFLVEGRPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVG
SPGVVCMIEMTADGKPPVQKKDTEISHASQAYFESMFLGHIPANVQIHKKAGPVYGFR
GCILDLQVNNKEFFIIDEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRL
YSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLCTDAINITQPRFSGTD
AFGYTSFLAYSRISDISFHYEFHLKFQLANNHSALQNNLIFFTGQKGHGLNGDDFLAV
GLLNGSVVYSYNLGSGIASIRSEPLNLSLGVHTVHLGKFFQEGWLKVDDHKNKSIIAP
GRLVGLNVFSQFYVGGYSEYTPDLLPNGADFKNGFQGCIFTLQVRTEKDGHFRGLGNP
EGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP
EHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASF
HVRKKTHIQLQFQPLAADGILFYAAQHLKAQSGDFLCISLVNSSVQLRYNLGDRTIIL
ETLQKVTINGSTWHIIKAGRVGAEGYLDLDGINVTEKASTKMSSLDTNTDFYIGGVSS
LNLVNPMAIENEPVGFQGCIRQVIINNQELQLTEFGAKGGSNVGDCDGTACGYNTCRN
GGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSCLCTLGWV
GRYCENKTSFSTAKFMGNSYIKYIDPNYRMRNLQFTTISLNFSTTKTEGLIVWMGIAQ
NEENDFLAIGLHNQTLKIAVNLGERISVPMSYNNGTFCCNKWHHVVVIQNQTLIKAYI
NNSLILSEDIDPHKNFVALNYDGICYLGGFEYGRKVNIVTQEIFKTNFVGKIKDVVFF
QEPKNIELIKLEGYNVYDGDEQNEVT"
BASE COUNT 3245 a 2088 c 2071 g 3193 t
ORIGIN
1 agaaacaaag tgatacacgc taggcatgtc cagacattaa ccgtaatcag aagcctccta
61 gggttgcaag cctccttggc taatggttgg gctttgtgcc tcactcttct cttacacctg
121 gggagtcaag tctggatcct ctgctccata tttatttagc aaataaaaca ctgatctcaa
181 acagcaacgg aacctgtgta cttgagtttt aaaggtgttt tttgaaaact aatcagaaga
241 ggaatgctta tctcccaaga aaattgaaac catctgtaaa agaatcttgg ctgtgctgtg
301 ttttgattag attgaagctt ggtgtaaaga gaaaacacaa aagaccgcag aatatttaca
361 acatttgaat tcctgtttct ccatcaaagc acattgtcat caaagctact ttgggtatag
421 aaaaaaggtc aattccaatt cccaggaatc cttaaccaca actttacttg gaaatttccg
481 gtaatactta aaacaccatt ttgcagcaat tctttatgat aaactgtaaa atacagctac
541 ccgaaaatga ctgacaaatc aatcgtcatt ctgagcctga tggtttttca cagctctttc
601 ataaatggaa aaacatgtag acggcaattg gtggaagaat ggcatccaca accctcatca
661 tatgtggtaa attggacact aacagaaaac atctgcttgg acttctacag agattgctgg
721 tttttgggtg taaacactaa aatagatact tcaggcaatc aagctgttcc ccagatttgc
781 cctttgcaaa ttcaattagg agatatcctt gtaatttctt ctgaaccatc tcttcaattt
841 ccagaaataa atttgatgaa tgtttctgaa acatctttcg ttggctgtgt gcaaaatacc
901 acaacggaag atcagttact ttttggctgc agactaaaag gaatgcacac tgttaattct
961 aagtggctga gtgttgggac acattatttt atcacagtta tggcaagtgg tccatcacct
1021 tgtccactgg gacttcgact aaatgtgaca gtgaaacagc agttctgcca ggaatctctg
1081 agttcagaat tttgctctgg tcatggtaaa tgtcttagtg aagcttggag caagacatat
1141 agctgccatt gccagcctcc attttctgga aaatactgcc aggaacttga tgcatgttct
1201 tttaaaccat gtaaaaataa tggcagttgc attaataaaa gagaaaattg ggatgagcaa
1261 gcatatgaat gtgtctgtca cccaccattt acaggaaaga attgctcaga aataattggc
1321 cagtgtcaac cacatgtctg tttccatgga aactgcagca atattacttc aaatagtttc
1381 atttgtgaat gtgatgagca attttcaggt ccattctgtg aggtgtcagc aaaaccttgt
1441 gtttctctgc ttttttggaa aagaggaatt tgcccaaata gcagttctgc ttatacttat
1501 gaatgcccaa aaggatcttc cagccaaaat ggtgaaactg atgtcagtga gttttcatta
1561 gtaccatgtc agaatggtac tgactgcatc aaaatatcaa atgatgttat gtgcatctgt
1621 tcaccaatat ttacagattt gctttgtaag agcattcaaa catcatgtga gtcatttcct
1681 ttgaggaata atgctacatg taagaaatgt gagaaagatt atccttgcag ctgtatatca
1741 ggatttactg aaaaaaactg tgagaaagca attgaccact gtaaactgct cagcatcaac
1801 tgtctgaatg aagaatggtg tttcaatata attggaagat tcaaatatgt atgcattcca
1861 gggtgcacaa aaaatccatg ttggtttttg aagaatgttt acctaattca tcaacacctc
1921 tgctactgtg gagtcacctt ccatggtatt tgccaagata aaggtcctgc tcaatttgaa
1981 tatgtgtggc aattgggatt tgcaggatct gaaggcgaaa agtgccaagg ggttattgat
2041 gcctatttct ttctggctgc aaactgcact gaagatgcaa cctatgtgaa cgatcctgaa
2101 gataataatt cttcatgttg gttcccacat gaaggcacaa aagagatttg tgcaaatgga
2161 tgcagttgtt tgagtgaaga agacagtcag gaatatcggt atctatgttt tctcagatgg
2221 gctggcaaca tgtatctgga aaatacaact gatgatcaag aaaatgagtg tcaacatgaa
2281 gctgtttgta aagatgaaat taatagaccc agatgcagct gttctcttag ttacattggc
2341 agattgtgtg ttgtcaatgt tgactattgc ttagggaacc acagtatatc agtgcatggc
2401 ctctgcctgg ccctttcgca caattgtaac tgtagcggtc tgcaaagata tgaaaggaac
2461 atctgtgaga tagatactga agactgcaaa tctgcgtcct gcaaaaatgg aacaactagt
2521 acacatttaa ggggatattt cttccgcaag tgtgtcccag gatttaaagg tacgcaatgt
2581 gaaattgata tagatgagtg tgcttcacat ccctgcaaaa atggagccac ctgcattgac
2641 caacctggta attacttctg ccagtgtgtg cctccattta aagtggttga tggcttttcc
2701 tgcttatgca atccaggcta tgttgggata agatgtgaac aggacattga tgactgcatc
2761 ctgaatgcct gtgagcacaa ttctacctgc aaagacctgc atctcagcta ccagtgtgtg
2821 tgcctatctg attgggaagg aaatttttgt gaacaagaat ccaatgagtg taaaatgaat
2881 ccttgcaaga acaattccac ctgtactgac ctttacaaaa gctatcgatg tgagtgtaca
2941 tctggatgga ctggacagaa ctgtagtgaa gaaataaatg aatgcgactc tgatccatgc
3001 atgaatggag gtctttgtca tgaatctacc atccctggac aatttgtatg tctgtgccca
3061 cccctttata ctggacaatt ttgccaccaa cgctataacc tttgtgacct acttcataac
3121 ccttgcagaa acaactcaac atgcttagct ttggtagacg caaatcagca ttgtatttgt
3181 agagaagaat ttgaaggtaa aaactgtgaa attgatgtga aagactgcct cttcctttcc
3241 tgccaggatt atggtgactg tgaagatatg gtcaacaatt tcaggtgtat ttgcagacct
3301 gggttttctg gatctctgtg tgaaattgaa attaatgaat gttcctctga accttgcaaa
3361 aataatggaa catgtgtgga tctgacaaac agattttttt gtaattgtga acctgagtac
3421 catgggccct tctgtgaact tgatgtaaat aaatgtaaaa tctcaccttg tctagatgaa
3481 gaaaattgtg tctacaggac tgatggatac aactgcctct gtgcccctgg ttatacaggc
3541 atcaactgtg aaataaatct agatgaatgc ctatcagagc cctgtctcca tgatggagtt
3601 tgtatcgatg gcatcaatca ttatacctgt gactgcaaga gtgggttttt tggaacacac
3661 tgtgaaacaa acgccaatga ttgcctttca aatccttgtc tacatggaag gtgcacagaa
3721 cttattaatg aatatccatg ttcatgtgat gcagatggga ctagcacaca atgtaagatc
3781 aaaattaatg actgcacatc aatcccttgt atgaatgaag gcttctgtca gaagtcagca
3841 catggattta cttgcatttg cccacgtgga tacactggtg catactgtga aaaaagcatt
3901 gataattgtg ctgagcctga acttaattca gtcatctgtc ttaatggagg gatctgtgtt
3961 gatgggcctg gacatacttt tgactgcaga tgtcttcctg gattttctgg tcaattttgt
4021 gaaattaata taaatgaatg ctcttcatca ccatgtctac atggtgcaga ctgtgaagat
4081 cacatcaatg gatatgtttg caaatgccaa ccaggatggt ctggacacca ctgtgagaat
4141 gagcttgagt gcattcccaa ctcatgtgtt catgaactct gcatggagaa tgaacctggc
4201 tcgacatgtt tatgcacacc tggatttatg acctgctcca ttgggcttct ttgtggtgat
4261 gaaataagga gaattacctg tttaactccc atctttcaaa gaacagatcc catttccaca
4321 cagacatata caattccccc ttctgagact ttggtcagca gctttccatc tataaaggct
4381 actagaatac cagccataat ggacacttac ccagttgatc aaggtccaaa acagacaggc
4441 attgtcaagc acgacattct cccaaccact ggtttggcaa cattaagaat tagcacaccc
4501 ttggaaagct acttactcca agaactgatt gtcactagag agctttcagc aaaacacagt
4561 cttctttctt ccgcagatgt ttcctcttct cgattcctga attttggtat tcgtgaccca
4621 gcacaaattg tccaggacaa aacatcggta tcacatatgc ctattcgaac ttcagcagcc
4681 acactaggtt tcttttttcc tgataggaga gcaaggaccc catttatcat gtcttcctta
4741 atgtcagatt ttatttttcc tacacaatct ttattatttg agaactgtca gactgttgct
4801 ttatctgcta ccccaacgac ttcagtaatt agaagcattc caggggctga tattgagcta
4861 aacaggcagt cattactctc ccgtggattc ctgcttatag ctgcctccat aagtgcaact
4921 ccagttgtct ctaggggggc tcaagaggat attgaagaat attcagctga ttctttaatt
4981 tcaagaagag agcactggag attgctcagc ccctcgatgt ctcccatttt tcctgctaag
5041 gtaattatat ctaaacaggt aaccatctta aactcatcag ctctgcaccg gttcagtaca
5101 aaagccttca atcccagtga atatcaggct attactgagg cttcaagcaa ccagagactc
5161 acaaacatca aatcacaggc tgctgattct ttaagagaat taagccaaac atgtgcaaca
5221 tgttctatga ctgaaataaa atcctctcgt gaattctcag atcaagtttt gcatagcaaa
5281 cagtcccact tttatgagac attctggatg aactcagcga tattagccag ctggtatgca
5341 ctaatgggag ctcaaactat cacttctggg cattcatttt cttctgctac tgaaataaca
5401 ccatcagtgg cattcacaga agtgccatct ttatttcctt ctaaaaagag tgcaaaaaga
5461 acaattttat cctcatcctt ggaagaatcc attaccctat caagtaattt ggatgttaat
5521 ttatgtttgg ataagacttg tttatccatt gtcccttcac aaactatctc ttcagacttg
5581 atgaattctg atttgacttc aaaaatgact actgatgaac tgtcagtatc agaaaacatt
5641 ttaaaactat tgaaaataag acaatatggc ataactatgg gacccactga ggtactaaat
5701 caagagagct tattggacat ggaaaaaagt aaaggatctc atacactgtt caaacttcac
5761 ccaagtgata gttctctgga ttttgagtta aacttacaaa tttatccgga tgttacttta
5821 aagacatatt cagaaattac acatgcaaat gacttcaaaa ataatctgcc accattgaca
5881 ggctcagtgc ctgatttttc agaagtcacc accaatgttg cattttatac agtttcagca
5941 actccagcac tttcaataca gacgtcttcc tccatgtctg taattaggcc agattggcca
6001 tattttacag attatatgac ctctcttaaa aaagaggtca agacttcttc agaatggtcc
6061 aaatgggaac ttcagcctag tgtgcaatat caggaatttc ccactgcaag ccggcatctt
6121 cccttcacta gatctcttac tttgtcttca ctggaatcca ttctggcacc tcaacggctg
6181 atgatttctg atttcagttg tgttcgttat tatggagatt cttatctaga atttcagaat
6241 gtggctttaa atccacaaaa taacatctcc ctagaatttc agaccttcag ctcctatgga
6301 cttctgctgt atgtcaagca agactcaaat ttagtagatg gattttttat tcaattgttt
6361 attgaaaatg gtactttaaa gtaccacttt tactgtcctg gtgaagcaaa atttaaaagc
6421 attaatacta ctgttagagt ggacaacggg caaaagtata cactgcttat caggcaagaa
6481 ttggatccat gtaacgctga gctgactatt ttagggagga atacacaaat atgcgaatct
6541 atcaatcatg tactcggaaa acccctgcca aaatcaggat ctgtcttcat tggtggattt
6601 ccagaccttc atgggaaaat ccagatgcct gtaccagtca agaattttac tggctgcata
6661 gaagttatag aaataaataa ctggagatct ttcattccat ccaaggcagt gaaaaactat
6721 cacattaaca attgcagatc ccagggattt atgctgtctc caacagcctc ctttgttgat
6781 gcttctgatg tgacacaagg ggttgatacc atgtggactt ctgtcagccc ctctgttgca
6841 gcaccctctg tgtgccagca ggatgtatgc cacaatggag gcacatgcca tgccatcttc
6901 ctctccagtg gcatagtgtc attccaatgt gactgtccac tacatttcac tggccgcttc
6961 tgtgaaaaag atgcaggttt attctttcca tctttcaatg ggaattccta tttagaactg
7021 ccctttttga agtttgtcct ggagaaggaa cataacagaa ctgttaccat ctacttgact
7081 ataaaaacaa acagtttaaa tggaactatt ctttacagta atgggaataa ttgtggaaag
7141 cagtttcttc atttatttct tgtggaagga aggccatcag ttaaatatgg gtgtggaaat
7201 tctcaaaata ttttgactgt ttctgctaat tacagcatta acacaaatgc attcacccct
7261 atcacaatac gctacacaac gcctgttggc agccctggag ttgtttgtat gattgaaatg
7321 actgcagatg gaaaacctcc agtacagaag aaagacacag agatttccca tgcctctcag
7381 gcatattttg aatcaatgtt ccttggccat attcctgcaa atgttcaaat tcataagaaa
7441 gcaggtcctg tttatgggtt caggggctgc attctagacc ttcaagtaaa caacaaagaa
7501 ttcttcatca tcgatgaagc acgacatgga aagaatattg agaactgcca cgtcccttgg
7561 tgtgctcatc atctgtgccg caacaatggc acctgcatca gtgataatga aaatctgttt
7621 tgtgagtgtc caaggctgta ttcaggcaag ctgtgccagt ttgcaagttg tgaaaacaac
7681 ccatgtggaa atggtgccac ctgtgttcca aaatccggaa cagatattgt ctgcctctgc
7741 ccatatggga ggtctggacc cctctgcact gatgctatta atattactca gccaaggttc
7801 agtggcacag atgcctttgg atacacctca ttcctggctt attcacggat ctcagacatc
7861 agcttccatt atgaattcca cctgaagttt cagctggcaa acaaccactc agcactgcaa
7921 aataacttga tattttttac tggacagaaa ggccatgggt tgaatggcga tgacttcctg
7981 gctgtgggcc tgctcaatgg cagtgtggtt tatagttata acctggggtc tggcatagca
8041 agcatcagga gcgagcccct caatctgagc cttggagtcc acactgttca tctgggcaag
8101 ttcttccaag agggctggct gaaggtagat gatcataaaa ataaatccat tatcgcccca
8161 ggaagactgg ttggtctcaa tgtcttcagt cagttttatg taggtggcta cagtgaatac
8221 actccagatc tcttaccaaa tggagcagat tttaaaaatg gttttcaagg ctgtattttc
8281 actcttcaag ttcgcactga gaaggatggc catttcagag gactgggaaa tcctgagggc
8341 cacccaaatg ctggacgcag tgttggccag tgtcatgctt ctccctgcag tttaatgaaa
8401 tgtggcaatg gtgggacatg catagagagt ggaactagtg tttactgcaa ttgtaccact
8461 gggtggaaag gatcattctg cacagagaca gtttctacct gtgatcctga acatgaccct
8521 ccacaccact gtagcagagg agcaacctgc atttcattac ctcatggata cacctgtttc
8581 tgtcctctag gaaccactgg aatctactgt gaacaagctt tatccataag tgatccatct
8641 ttcagaagca atgagttatc ctggatgtct tttgcttcct ttcatgttcg aaaaaagaca
8701 catattcaat tgcagtttca gcctctcgct gcagatggta tcctatttta tgctgcacaa
8761 cacttaaaag cccaatcagg tgatttttta tgcatctctt tagtaaatag ttccgttcaa
8821 cttcgctaca accttggcga cagaactatc attctagaaa ctctccaaaa agtaactata
8881 aacggaagta cttggcatat aataaaagca ggaagagttg gtgcagaagg ctacctggat
8941 ctagatggga taaatgtaac agaaaaggcc tccactaaaa tgagttctct ggacacaaat
9001 acagacttct atattggagg agtatcttct ttaaatcttg taaatcccat ggcaatagaa
9061 aatgaacctg taggttttca aggctgtatc cgacaagtta tcataaataa tcaagaatta
9121 caattaactg aatttggagc aaaaggtggc tcaaatgtag gtgactgtga tgggacagcc
9181 tgtgggtaca acacatgcag aaatggaggt gaatgtacag taaatggcac aactttttct
9241 tgcagatgtt tgccagattg ggctggaaat acatgtaacc agtctgtgtc ctgtttgaat
9301 aatctttgcc tccaccaatc tttatgtata cctgaccaat cattttctta cagttgcctg
9361 tgtactttgg gttgggtggg aaggtattgt gaaaacaaaa cttcattttc aactgcaaaa
9421 tttatgggta attcttacat taaatacatt gatccaaatt atagaatgag aaacctccag
9481 ttcactacta tatccttaaa tttcagtacc actaaaacag aaggtctaat tgtatggatg
9541 ggaatagctc aaaatgaaga aaatgatttt ctggcaattg gtctccataa tcagaccttg
9601 aaaatagcag ttaacttggg agaaagaatc tctgtgccta tgagctataa caatggcaca
9661 ttctgttgta ataaatggca ccatgtagtt gtaattcaaa atcagactct tatcaaggcc
9721 tacataaata acagtctaat tctttccgag gatattgatc cacataaaaa ctttgtggct
9781 ctaaactatg atggcatttg ttatctaggg ggctttgaat atggtagaaa ggtaaatatc
9841 gttactcaag agatttttaa aaccaatttt gttggcaaaa ttaaagatgt tgtatttttt
9901 caggaaccaa aaaacattga actaattaaa ttagaaggat acaatgttta tgatggagat
9961 gaacaaaatg aggttacata agttaacact agagatttta gtacacacta tacataaatg
10021 cagttatttt gatagttatt tctttgatac attgcttacg gggaatcaac tgtttactat
10081 attacctgaa atagtctaaa tgctaacata tctttttgat aagattgtaa aatgtcactg
10141 aaggttctga ttgtttttcc tacatctaat ttatctgtat atattttgat tcatgtttta
10201 actccattag ttcagtgctt attcacagaa tgtgcttatt cactttgctt attcactttt
10261 tacctatccc taatgcttac attttaaaat caacgtgtaa acacaatttt aaaaatcaat
10321 gtgtaagctg aactttaaaa tgtttaaaat tcagttggga atgaattagg gataggtaca
10381 aataagaaaa aaatcaagtt attaatcaaa ggaaaaataa aaattataca aagcaatgta
10441 accatattgt attacatggc ttagctacaa cttatttata tgattcaaca atgtaaaact
10501 tgaacataga tttaaaccaa aaattattgc atgaatgtag aaagagaagg tgagaggaga
10561 ggagaacagg ctggtaagag ctaaatcctt atctttt
//