LOCUS EU978936 1866 bp mRNA linear HUM 15-SEP-2008
DEFINITION Homo sapiens K2P5.1 potassium channel (KCNK5) mRNA, complete cds.
ACCESSION EU978936
VERSION EU978936.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1866)
AUTHORS Gierten,J., Ficker,E., Bloehs,R., Schlomer,K., Kathofer,S.,
Scholz,E., Zitron,E., Kiesecker,C., Bauer,A., Becker,R.,
Katus,H.A., Karle,C.A. and Thomas,D.
TITLE Regulation of two-pore-domain (K2P) potassium leak channels by the
tyrosine kinase inhibitor genistein
JOURNAL Br. J. Pharmacol. 154 (8), 1680-1690 (2008)
PUBMED 18516069
REFERENCE 2 (bases 1 to 1866)
AUTHORS Thomas,D.
TITLE Direct Submission
JOURNAL Submitted (04-AUG-2008) Department of Cardiology, Medical
University Hospital Heidelberg, Im Neuenheimer Feld 410, Heidelberg
D-69120, Germany
FEATURES Location/Qualifiers
source 1..1866
/db_xref="H-InvDB:HIT000558379"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
gene 1..1866
/gene="KCNK5"
/gene_synonym="TASK-2"
/gene_synonym="TASK2"
CDS 151..1650
/gene="KCNK5"
/gene_synonym="TASK-2"
/gene_synonym="TASK2"
/note="two-pore-domain potassium channel subunit;
TWIK-related acid-sensitive K+ channel 2; potassium
channel subfamily K member 5"
/codon_start=1
/product="K2P5.1 potassium channel"
/protein_id="ACH86095.1"
/translation="MVDRGPLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLH
LLKEFPCLGQEGLDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYG
NVAPKTPAGRLFCVFYGLFGVPLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQI
TCTVIFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSAN
YHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKA
LQVKGSTASKDVNIFSFLSKKEETYNDLIKQIGKKAMKTSGGGETGPGPGLGPQGGGL
PALPPSLVPLVVYSKNRVPTLEEVSQTLRSKGHVSRSPDEEAVARAPEDSSPAPEVFM
NQLDRISEECEPWDAQDYHPLIFQDASITFVNTEAGLSDEETSKSSLEDNLAGEESPQ
QGAEAKAPLNMGEFPSSSESTFTSTESELSVPYEQLMNEYNKANSPKGT"
BASE COUNT 384 a 557 c 573 g 352 t
ORIGIN
1 ggggagcggt gcttgcgggg ggtgagtacc gggcactgcg catgcggagc tccaaattca
61 aacagctgtt ttcagaggct ggagggcggg cggactggta gcagctgggg ctaggagagg
121 ctttctctag gaggcggccg ctcgggagcc atggtggacc ggggccctct gctcacctcg
181 gccatcatct tctacctggc catcggggcg gcgatcttcg aagtgctgga ggagccacac
241 tggaaggagg ccaagaaaaa ctactacaca cagaagctgc atctgctcaa ggagttcccg
301 tgcctgggtc aggagggcct ggacaagatc ctagaggtgg tatctgatgc tgcaggacag
361 ggtgtggcca tcacagggaa ccagaccttc aacaactgga actggcccaa tgcaatgatt
421 tttgcagcga ccgtcattac caccattgga tatggcaatg tggctcccaa gacccccgcc
481 ggtcgcctct tctgtgtttt ctatggtctc ttcggggtgc cgctctgcct gacgtggatc
541 agtgccctgg gcaagttctt cgggggacgt gccaagagac tagggcagtt ccttaccaag
601 agaggtgtga gtctgcggaa ggcgcagatc acgtgcacag tcatcttcat cgtgtggggc
661 gtcctagtcc acctggtgat cccacccttc gtattcatgg tgactgaggg gtggaactac
721 atcgagggcc tctactactc cttcatcacc atctccacca tcggcttcgg tgactttgtg
781 gccggtgtga accccagcgc caactaccac gccctgtacc gctacttcgt ggagctctgg
841 atctacttgg ggctggcctg gctgtccctt tttgtcaact ggaaggtgag catgtttgtg
901 gaagtccaca aagccattaa gaagcggcgg cggcgacgga aggagtcctt tgagagctcc
961 ccacactccc ggaaggccct gcaggtgaag gggagcacag cctccaagga cgtcaacatc
1021 ttcagctttc tttccaagaa ggaagagacc tacaacgacc tcatcaagca gatcgggaag
1081 aaggccatga agacaagcgg gggtggggag acgggcccgg gcccagggct ggggcctcaa
1141 ggcggtgggc tcccagcact gcccccttcc ctggtgcccc tggtagtcta ctccaagaac
1201 cgggtgccca ccttggaaga ggtgtcacag acactgagga gcaaaggcca cgtatcaagg
1261 tccccagatg aggaggctgt ggcacgggcc cctgaagaca gctcccctgc ccccgaggtg
1321 ttcatgaacc agctggaccg catcagcgag gaatgcgagc catgggacgc ccaggactac
1381 cacccactca tcttccagga cgccagcatc accttcgtga acacggaggc tggcctctca
1441 gacgaggaga cctccaagtc ctcgctagag gacaacttgg caggggagga gagcccccag
1501 cagggggctg aagccaaggc gcccctgaac atgggcgagt tcccctcctc ctccgagtcc
1561 accttcacca gcactgagtc tgagctctct gtgccttacg aacagctgat gaatgagtac
1621 aacaaggcta acagccccaa gggcacatga ggcagggccg gctccccacc ccacctttga
1681 tggcctcttc ccccctcacc ctagggtgtc ccgagatgac cgggacgcct ggcccctggt
1741 gggggggcag cctcggaact gggagtgggg ggccaggggc cttcctaacc ttccatcatc
1801 ctcagctaga tgtatgcccg ggacagggcc tctgttctcc agctgaacca taccctggct
1861 gtgggg
//