LOCUS EU826582 1488 bp mRNA linear HUM 23-JUL-2008
DEFINITION Homo sapiens soluble RON variant 1 (RON) mRNA, complete cds,
alternatively spliced.
ACCESSION EU826582
VERSION EU826582.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1488)
AUTHORS Jin,P., Zhang,J., Sumariwalla,P.F., Ni,I., Jorgensen,B.,
Crawford,D., Phillips,S., Feldmann,M., Shepard,H.M. and
Paleolog,E.M.
TITLE Novel splice variants derived from the receptor tyrosine kinase
superfamily are potential therapeutics for rheumatoid arthritis
JOURNAL Arthritis Res. Ther. 10 (4), R73 (2008)
PUBMED 18593464
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 1488)
AUTHORS Jin,P., Zhang,J., Ni,I. and Shepard,H.M.
TITLE Direct Submission
JOURNAL Submitted (15-JUN-2008) Receptor Biologix, 3350 West Bayshore Road,
Ste. 150, Palo Alto, CA 94303, USA
FEATURES Location/Qualifiers
source 1..1488
/db_xref="H-InvDB:HIT000558167"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
gene 1..1488
/gene="RON"
CDS 1..1488
/gene="RON"
/note="alternatively spliced; extracellular domain"
/codon_start=1
/product="soluble RON variant 1"
/protein_id="ACF47618.1"
/translation="MELLPPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKY
VVPSFSAGGLVQAMVTYEGDRNESAVFVAIRNRLHVLGPDLKSVQSLATGPAGDPGCQ
TCAACGPGPHGPPGDTDTKVLVLDPALPALVSCGSSLQGRCFLHDLEPQGTAVHLAAP
ACLFSAHHNRPDDCPDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRSVSI
RRLKADASGFAPGFVALSVLPKHLVSYSIEYVHSFHTGAFVYFLTVQPASVTDDPSAL
HTRLARLSATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVLRVAHSAPVGAQLA
TELSIAEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDEGVERCCESPVHP
GLRRGLDFFQSPSFCPNPPGLEALSPNTSCRHFPLLVSSSFSRVDLFNGLLGPVQVTA
LYVTRLDNVTVAHMGTMDGRILQVGPHPHSPLALGPCLHPHFAHI"
BASE COUNT 248 a 495 c 428 g 317 t
ORIGIN
1 atggagctcc tcccgccgct gcctcagtcc ttcctgttgc tgctgctgtt gcctgccaag
61 cccgcggcgg gcgaggactg gcagtgcccg cgcaccccct acgcggcctc tcgcgacttt
121 gacgtgaagt acgtggtgcc cagcttctcc gccggaggcc tggtacaggc catggtgacc
181 tacgagggcg acagaaatga gagtgctgtg tttgtagcca tacgcaatcg cctgcatgtg
241 cttgggcctg acctgaagtc tgtccagagc ctggccacgg gccctgctgg agaccctggc
301 tgccagacgt gtgcagcctg tggcccagga ccccacggcc ctcccggtga cacagacaca
361 aaggtgctgg tgctggatcc cgcgctgcct gcgctggtca gttgtggctc cagcctgcag
421 ggccgctgct tcctgcatga cctagagccc caagggacag ccgtgcatct ggcagcgcca
481 gcctgcctct tctcagccca ccataaccgg cccgatgact gccccgactg tgtggccagc
541 ccattgggca cccgtgtaac tgtggttgag caaggccagg cctcctattt ctacgtggca
601 tcctcactgg acgcagccgt ggctgccagc ttcagcccac gctcagtgtc tatcaggcgt
661 ctcaaggctg acgcctcggg attcgcaccg ggctttgtgg cgttgtcagt gctgcccaag
721 catcttgtct cctacagtat tgaatacgtg cacagcttcc acacgggagc cttcgtatac
781 ttcctgactg tacagccggc cagcgtgaca gatgatccta gtgccctgca cacacgcctg
841 gcacggctta gcgccactga gccagagttg ggtgactatc gggagctggt cctcgactgc
901 agatttgctc caaaacgcag gcgccggggg gccccagaag gcggacagcc ctaccctgtg
961 ctgcgggtgg cccactccgc tccagtgggt gcccaacttg ccactgagct gagcatcgcc
1021 gagggccagg aagtactatt tggggtcttt gtgactggca aggatggtgg tcctggcgtg
1081 ggccccaact ctgtcgtctg tgccttcccc attgacctgc tggacacact aattgatgag
1141 ggtgtggagc gctgttgtga atccccagtc catccaggcc tccggcgagg cctcgacttc
1201 ttccagtcgc ccagtttttg ccccaacccg cctggcctgg aagccctcag ccccaacacc
1261 agctgccgcc acttccctct gctggtcagt agcagcttct cacgtgtgga cctattcaat
1321 gggctgttgg gaccagtaca ggtcactgca ttgtatgtga cacgccttga caacgtcaca
1381 gtggcacaca tgggcacaat ggatgggcgt atcctgcagg tgggtcctca tccccacagt
1441 cccctagccc tgggtccttg tctccatccc cattttgctc acatctga
//